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List of works by Dora Dias-Santagata

A Platform for Rapid Detection of Multiple Oncogenic Mutations With Relevance to Targeted Therapy in Non–Small-Cell Lung Cancer ⬇️

scientific article published on December 23, 2010

A potential role for targeted therapy in a subset of metastasizing adnexal carcinomas ⬇️

scientific article published on March 18, 2011

ALK Rearrangements Are Mutually Exclusive with Mutations in EGFR or KRAS: An Analysis of 1,683 Patients with Non–Small Cell Lung Cancer ⬇️

scientific article published on May 31, 2013

Acquired Resistance to Crizotinib in NSCLC with MET Exon 14 Skipping

scientific article published on 22 June 2016

Activation of PI3K Signaling in Merkel Cell Carcinoma ⬇️

scientific article published on January 18, 2012

Apocrine-Eccrine Carcinomas: Molecular and Immunohistochemical Analyses ⬇️

scientific article published on October 9, 2012

BIM expression in treatment-naive cancers predicts responsiveness to kinase inhibitors.

scientific article published on 22 July 2011

BRAF V600E Mutation Identifies a Subset of Low-Grade Diffusely Infiltrating Gliomas in Adults ⬇️

scientific article published on May 10, 2013

BRAF V600E mutations are common in pleomorphic xanthoastrocytoma: diagnostic and therapeutic implications

scientific article

BRAF gene amplification can promote acquired resistance to MEK inhibitors in cancer cells harboring the BRAF V600E mutation ⬇️

scientific article published on November 23, 2010

Characteristics of lung cancers harboring NRAS mutations

scientific article (publication date: May 2013)

Clinical Acquired Resistance to RAF Inhibitor Combinations in BRAF-Mutant Colorectal Cancer through MAPK Pathway Alterations

scientific article

Colorectal cancer in Crohn's colitis is comparable to sporadic colorectal cancer.

scientific article published on 30 March 2016

Cytological, molecular, and clinical features of noninvasive follicular thyroid neoplasm with papillary-like nuclear features versus invasive forms of follicular variant of papillary thyroid carcinoma.

scientific article

De novo ALK kinase domain mutations are uncommon in kinase inhibitor-naïve ALK rearranged lung cancers

scientific article

Decreased survival in EGFR gene amplified vulvar carcinoma

scientific article published on 3 September 2008

Detection of Dual IDH1 and IDH2 Mutations by Targeted Next-Generation Sequencing in Acute Myeloid Leukemia and Myelodysplastic Syndromes.

scientific article

Detection of novel actionable genetic changes in salivary duct carcinoma helps direct patient treatment

scientific article

EGFR-Mediated Reactivation of MAPK Signaling Contributes to Insensitivity of BRAF-Mutant Colorectal Cancers to RAF Inhibition with Vemurafenib ⬇️

scientific article published on January 16, 2012

Elevated CRAF as a potential mechanism of acquired resistance to BRAF inhibition in melanoma

scientific article

Exome sequencing identifies BRAF mutations in papillary craniopharyngiomas

scientific article

Frequent Mutation of Isocitrate Dehydrogenase (IDH)1 and IDH2 in Cholangiocarcinoma Identified Through Broad-Based Tumor Genotyping ⬇️

scientific article published on December 16, 2011

Genomic and immunohistochemical analysis in human adrenal cortical neoplasia reveal beta-catenin mutations as potential prognostic biomarker

scientific article

Genotypic and histological evolution of lung cancers acquiring resistance to EGFR inhibitors

scientific article

Heterogeneity Underlies the Emergence of EGFRT790 Wild-Type Clones Following Treatment of T790M-Positive Cancers with a Third-Generation EGFR Inhibitor

scientific article published on May 2015

Histologic and cytomorphologic features of ALK-rearranged lung adenocarcinomas ⬇️

scientific article published on June 29, 2012

Hobnail variant of papillary thyroid carcinoma: an institutional case series and molecular profile

scientific article

Identification of insertions in PTEN and TP53 in anaplastic thyroid carcinoma with angiogenic brain metastasis.

scientific article

Identification of mutations in CUL7 in 3-M syndrome

scientific article

Identification of oncogenic mutations and gene fusions in the follicular variant of papillary thyroid carcinoma.

scientific article

Inactivation of the tumor suppressor WTX in a subset of pediatric tumors

scientific article published on 05 November 2013

Intraoperative mass spectrometry mapping of an onco-metabolite to guide brain tumor surgery

scientific article

Lung cancers with acquired resistance to EGFR inhibitors occasionally harbor BRAF gene mutations but lack mutations in KRAS, NRAS, or MEK1.

scientific article

Malignant neurocristic hamartoma: a tumor distinct from conventional melanoma and malignant blue nevus

scientific article published on October 2011

Merkel Cell Carcinoma: 30-Year Experience from a Single Institution ⬇️

scientific article published on December 1, 2012

Metastasis-associated MCL1 and P16 copy number alterations dictate resistance to vemurafenib in a BRAFV600E patient-derived papillary thyroid carcinoma preclinical model.

scientific article published on 30 November 2015

Multi-institutional Oncogenic Driver Mutation Analysis in Lung Adenocarcinoma: The Lung Cancer Mutation Consortium Experience

scientific article published on May 2015

Mutational analysis and clinical correlation of metastatic colorectal cancer

scientific article

NRAS mutations are rare in colorectal cancer

scientific article

Oncogenic PI3K mutations are as common as AKT1 and SMO mutations in meningioma

scientific article published on 28 January 2016

Preexistence and clonal selection of MET amplification in EGFR mutant NSCLC.

scientific article

Primary Benign and Malignant Thyroid Neoplasms With Signet Ring Cells: Cytologic, Histologic, and Molecular Features.

scientific article

Prospective, high-throughput molecular profiling of human gliomas ⬇️

scientific article published on July 22, 2012

Pulmonary adenocarcinoma mutation profile in smokers with smoking-related interstitial fibrosis

scientific article

Rapid targeted mutational analysis of human tumours: a clinical platform to guide personalized cancer medicine

scientific article published on May 2010

Routine multiplex mutational profiling of melanomas enables enrollment in genotype-driven therapeutic trials

scientific article (publication date: 2012)

Standardized decision support in next generation sequencing reports of somatic cancer variants

scientific article published on 04 April 2014

Synthetic lethal interaction of combined BCL-XL and MEK inhibition promotes tumor regressions in KRAS mutant cancer models

scientific article

Targetable signaling pathway mutations are associated with malignant phenotype in IDH-mutant gliomas.

scientific article

Tau phosphorylation sites work in concert to promote neurotoxicity in vivo

scientific article

The CUL7 E3 ubiquitin ligase targets insulin receptor substrate 1 for ubiquitin-dependent degradation

scientific article

The dichotomy in carcinogenesis of the distal esophagus and esophagogastric junction: intestinal-type vs cardiac-type mucosa-associated adenocarcinoma.

scientific article published on 13 May 2011

The reprogramming of tumor stroma by HSF1 is a potent enabler of malignancy

scientific article

Tumor islands in resected early-stage lung adenocarcinomas are associated with unique clinicopathologic and molecular characteristics and worse prognosis

scientific article published on February 2013

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