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List of works by Arjen Scholten

A Proteomics Approach to Identify New Putative Cardiac Intercalated Disk Proteins

scientific article

A chemical proteomics based enrichment technique targeting the interactome of the PDE5 inhibitor PF-4540124.

scientific article published on 13 March 2009

A multi-angular mass spectrometric view at cyclic nucleotide dependent protein kinases: in vivo characterization and structure/function relationships

scientific article published on July 2008

A small novel A-kinase anchoring protein (AKAP) that localizes specifically protein kinase A-regulatory subunit I (PKA-RI) to the plasma membrane.

scientific article

A systematic evaluation of protein kinase A-A-kinase anchoring protein interaction motifs.

scientific article

A tissue based chemical proteomics screen to identify novel G-kinase associated proteins (GKAPs)

article published in 2013

Alterations in the cerebellar (Phospho)proteome of a cyclic guanosine monophosphate (cGMP)-dependent protein kinase knockout mouse

scientific article

Anchored protein kinase A signalling in cardiac cellular electrophysiology

scientific article published on 12 September 2014

Applications of stable isotope dimethyl labeling in quantitative proteomics

scientific article published on 27 May 2012

Charting the interactome of PDE3A in human cells using an IBMX based chemical proteomics approach.

scientific article published on 24 July 2015

Collagen stimulation of platelets induces a rapid spatial response of cAMP and cGMP signaling scaffolds.

scientific article

Combining Deep Sequencing, Proteomics, Phosphoproteomics, and Functional Screens To Discover Novel Regulators of Sphingolipid Homeostasis

scientific article published on 29 November 2016

Deciphering the molecular mechanisms underlying sea urchin reversible adhesion: A quantitative proteomics approach

scientific article published on 26 February 2016

Deep Proteome Profiling of Circulating Granulocytes Reveals Bactericidal/Permeability-Increasing Protein as a Biomarker for Severe Atherosclerotic Coronary Stenosis

Defining the molecular targets of cerebellar PKG by quantitative (phospho)proteomics in a knock-out mouse model.

scientific article published on 29 August 2013

Determining protein concentrations of the human ventricular proteome

scientific article published in January 2013

HUPO 2011: The new Cardiovascular Initiative - integrating proteomics and cardiovascular biology in health and disease

scientific article published on March 2012

High precision platelet releasate definition by quantitative reversed protein profiling--brief report

scientific article published on 2 May 2013

Human CD62Ldim neutrophils identified as a separate subset by proteome profiling and in vivo pulse-chase labeling.

scientific article published on 17 May 2017

Huntingtin-associated protein 1 (HAP1) is a cGMP-dependent kinase anchoring protein (GKAP) specific for the cGMP-dependent protein kinase Iβ isoform.

scientific article

Identification of enriched PTM crosstalk motifs from large-scale experimental data sets.

scientific article

In-depth quantitative cardiac proteomics combining electron transfer dissociation and the metalloendopeptidase Lys-N with the SILAC mouse

scientific article

Integrated Proteomics Unveils Nuclear PDE3A2 as a Regulator of Cardiac Myocyte Hypertrophy

Interrogating cAMP-dependent kinase signaling in Jurkat T cells via a protein kinase A targeted immune-precipitation phosphoproteomics approach.

scientific article

Phosphoproteomics study based on in vivo inhibition reveals sites of calmodulin-dependent protein kinase II regulation in the heart

scientific article published on 7 August 2013

Probing the specificity of protein-protein interactions by quantitative chemical proteomics

scientific article published in January 2012

Protease bias in absolute protein quantitation.

scientific article published on 30 May 2012

Proteome-wide protein concentrations in the human heart.

scientific article

Proteomic dataset of the sea urchin Paracentrotus lividus adhesive organs and secreted adhesive

scientific article

Quantitative proteomics analysis reveals similar release profiles following specific PAR-1 or PAR-4 stimulation of platelets

article

Reorganized PKA-AKAP associations in the failing human heart.

scientific article

Revealing promiscuous drug-target interactions by chemical proteomics.

scientific article published on 23 July 2009

Selectivity in enrichment of cAMP-dependent protein kinase regulatory subunits type I and type II and their interactors using modified cAMP affinity resins.

scientific article published on 31 December 2008

Separation of PKA and PKG signaling nodes by chemical proteomics.

scientific article published on January 2015

Simultaneous assessment of kinetic, site-specific, and structural aspects of enzymatic protein phosphorylation.

scientific article published on 9 July 2014

Spatial Organization in Protein Kinase A Signaling Emerged at the Base of Animal Evolution.

scientific article

Sphingosine kinase interacting protein is an A-kinase anchoring protein specific for type I cAMP-dependent protein kinase

scientific article

Structure of smAKAP and its regulation by PKA-mediated phosphorylation.

scientific article published on 30 March 2016

Targeted phosphotyrosine profiling of glycoprotein VI signaling implicates oligophrenin-1 in platelet filopodia formation

scientific article published on 25 April 2013

cGMP-binding prepares PKG for substrate binding by disclosing the C-terminal domain.

scientific article

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