List of works - Alison Pattie

A study of common Mendelian disease carriers across ageing British cohorts: meta-analyses reveal heterozygosity for alpha 1-antitrypsin deficiency increases respiratory capacity and height

scientific article published on February 2016

Age-dependent DNA methylation patterns on the Y chromosome in elderly males

scientific article published on 21 February 2019

Age-related gene expression changes, and transcriptome wide association study of physical and cognitive aging traits, in the Lothian Birth Cohort 1936.

scientific article published in December 2017

An epigenetic predictor of death captures multi-modal measures of brain health

scientific article published on 03 December 2019

Apolipoprotein E genotype does not moderate the associations of depressive symptoms, neuroticism and allostatic load with cognitive ability and cognitive aging in the Lothian Birth Cohort 1936.

scientific article published on 16 February 2018

Apolipoprotein e gene variability and cognitive functions at age 79: a follow-up of the Scottish mental survey of 1932.

scientific article published in June 2004

Archival sources for Sir Godfrey Hilton Thomson

scientific article

Associations between education and brain structure at age 73 years, adjusted for age 11 IQ.

scientific article published on 24 September 2016

Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits

article

Associations of autozygosity with a broad range of human phenotypes

scientific article published on 31 October 2019

Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function ⬇️

scientific article published on 01 May 2019

Beyond a bigger brain: Multivariable structural brain imaging and intelligence

scientific article

Brain Structural Differences Between 73- And 92-Year Olds Matched For Childhood Intelligence, Social Background, And Intracranial Volume

Brain cortical characteristics of lifetime cognitive ageing

scientific article published on 6 September 2017

Brain structural differences between 73- and 92-year olds matched for childhood intelligence, social background, and intracranial volume

scientific article

Brain volumetric changes and cognitive ageing during the eighth decade of life

scientific article published on 7 September 2015

Carotid disease at age 73 and cognitive change from age 70 to 76 years: A longitudinal cohort study

scientific article published on January 2016

Childhood intelligence in relation to major causes of death in 68 year follow-up: prospective population study

scientific article

Cognitive change and the APOE epsilon 4 allele

scientific article (publication date: 29 August 2002)

Cognitive consequences of overweight and obesity in the ninth decade of life?

scientific article published on 23 September 2014

Cohort Profile Update: The Lothian Birth Cohorts of 1921 and 1936.

scientific article published on 12 March 2018

Cohort profile for the STratifying Resilience and Depression Longitudinally (STRADL) study: A depression-focused investigation of Generation Scotland, using detailed clinical, cognitive, and neuroimaging assessments

scientific article published in 2019

Cohort profile: the Lothian Birth Cohorts of 1921 and 1936.

scientific article

Computational quantification of brain perivascular space morphologies: Associations with vascular risk factors and white matter hyperintensities. A study in the Lothian Birth Cohort 1936

scientific article published on 09 December 2019

Continued concern about nutritional supplements and cognitive function in the elderly

scientific article published on 01 March 2004

Correction: The complex genetics of gait speed: genome-wide meta-analysis approach

scientific article published on 7 July 2017

Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses

scientific article published on November 2016

Coupled changes in brain white matter microstructure and fluid intelligence in later life

scientific article published on June 2015

Coupled changes in hippocampal structure and cognitive ability in later life.

scientific article published on 4 January 2018

DNA methylation age of blood predicts all-cause mortality in later life

scientific article

Diffusion tensor and magnetization transfer MRI measurements of periventricular white matter hyperintensities in old age.

scientific article

Does cognitive ability predict mortality in the ninth decade? The Lothian Birth Cohort 1921

article by Catherine Murray et al published September 2012 in Intelligence

Does incipient dementia explain normal cognitive decline determinants? Lothian birth cohort 1921.

scientific article published on 10 May 2018

Early life characteristics and late life burden of cerebral small vessel disease in the Lothian Birth Cohort 1936.

scientific article published on 19 September 2016

Effect of smoking on physical and cognitive capability in later life: a multicohort study using observational and genetic approaches

scientific article

Erratum: Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms and neuroticism identified through genome-wide analyses

article

Exploratory analysis of age and sex dependent DNA methylation patterns on the X-chromosome in whole blood samples

scientific article published on 28 April 2020

Fluctuating asymmetry in brain structure and general intelligence in 73-year-olds

scientific article published on 01 January 2020

Fluid Intelligence Predicts Change in Depressive Symptoms in Later Life: The Lothian Birth Cohort 1936

scientific article published on 25 October 2018

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scientific article published on 17 September 2018

Genetic analysis of over one million people identifies 535 novel loci for blood pressure

Genetic and environmental exposures constrain epigenetic drift over the human life course

scientific article

Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses

scientific article published on 18 April 2016

Genome-wide analysis identifies 12 loci influencing human reproductive behavior

scientific article

Genome-wide studies of verbal declarative memory in nondemented older people: the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium

scientific article

Harmonization of Neuroticism and Extraversion phenotypes across inventories and cohorts in the Genetics of Personality Consortium: an application of Item Response Theory

scientific article published on 15 May 2014

Height and intelligence in the Lothian Birth Cohort 1921: a longitudinal study

scientific article published on 11 January 2010

Impact of small vessel disease in the brain on gait and balance

scientific article published on 30 January 2017

Interaction of APOE e4 and poor glycemic control predicts white matter hyperintensity growth from 73 to 76

scientific article

Lack of association between polymorphisms in angiotensin-converting-enzyme and methylenetetrahydrofolate reductase genes and normal cognitive ageing in humans

scientific article published in August 2003

Life long changes in cognitive ability are associated with prescribed medications in old age.

scientific article published on April 2004

Life review in Scottish ninety year olds from the Lothian birth cohort 1921: Developing qualitative methodology in a longitudinal study

scientific article published in 2012

Life review in advanced age: qualitative research on the 'start in life' of 90-year-olds in the Lothian Birth Cohort 1921.

scientific article

Lifecourse Activity Participation From Early, Mid, and Later Adulthood as Determinants of Cognitive Aging: The Lothian Birth Cohort 1921.

scientific article published on 07 October 2016

Lifetime intellectual function and satisfaction with life in old age: longitudinal cohort study.

scientific article

Longitudinal telomere length shortening and cognitive and physical decline in later life: The Lothian Birth Cohorts 1936 and 1921.

scientific article published on 10 February 2016

Losing one's grip: a bivariate growth curve model of grip strength and nonverbal reasoning from age 79 to 87 years in the Lothian Birth Cohort 1921.

scientific article published on 9 July 2011

Mental ability in childhood and cognitive aging

scientific article

More intelligent, more dependable children live longer: a 55-year longitudinal study of a representative sample of the Scottish nation

scientific article published on 01 September 2008

Neurology-related protein biomarkers are associated with cognitive ability and brain volume in older age

scientific article published on 10 February 2020

Ninety-nine independent genetic loci influencing general cognitive function include genes associated with brain health and structure (N = 280,360)

Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney

scientific article

Oxidative stress, telomere length and biomarkers of physical aging in a cohort aged 79 years from the 1932 Scottish Mental Survey

scientific article published on 14 October 2008

Personality Polygenes, Positive Affect, and Life Satisfaction

scientific article published on 22 August 2016

Polygenic predictors of age-related decline in cognitive ability

scientific article published on 13 February 2019

Predictors of ageing-related decline across multiple cognitive functions

scientific article

Predictors of gait speed and its change over three years in community-dwelling older people

scientific article

Predictors of tooth loss in the 1921 Lothian Birth Cohort

scientific article published on 21 November 2007

Progression of White Matter Disease and Cortical Thinning Are Not Related in Older Community-Dwelling Subjects

scientific article published on 22 December 2015

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 22 December 2017

Psychosocial factors and health as determinants of quality of life in community-dwelling older adults

scientific article published on 26 June 2011

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scholarly article published in Nature Genetics

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

erratum

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 16 March 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 01 July 2019

Rare and low-frequency coding variants alter human adult height

scientific article (publication date: February 2017)

Retinal microvascular network geometry and cognitive abilities in community-dwelling older people: The Lothian Birth Cohort 1936 study.

scientific article published on 17 October 2016

Retinal vascular image analysis as a potential screening tool for cerebrovascular disease: a rationale based on homology between cerebral and retinal microvasculatures.

scientific article

Risk and protective factors for structural brain ageing in the eighth decade of life.

scientific article published on 19 April 2017

Shared genetic aetiology between cognitive ability and cardiovascular disease risk factors: Generation Scotland's Scottish family health study

article

Sleep and brain morphological changes in the eighth decade of life

scientific article published on 24 July 2019

Social class, gender and secondary education in Scotland in the 1950s

article

Stability and change in intelligence from age 11 to ages 70, 79, and 87: The Lothian Birth Cohorts of 1921 and 1936

article

Structural Brain Asymmetry and General Intelligence in 73-Year-Olds

Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function ⬇️

scientific article published on 29 May 2018

Supplementation and the elderly: dramatic results?

scientific article published on 01 April 2002

Symmetric faces are a sign of successful cognitive aging

article

THE LONG ARMS OF CHILDHOOD INTELLIGENCE AND EDUCATION ON TERMINAL DECLINE: EVIDENCE FROM LOTHIAN BIRTH COHORT 1921

scholarly article in Innovation in Aging, vol. 3, Suppl 1, November 2019

The Influence of Dyslexia Candidate Genes on Reading Skill in Old Age

article

The association between retinal vascular network geometry and cognitive ability in an elderly population

scientific article published in May 2007

The cognitive cost of being a twin: two whole-population surveys

scientific article published in August 2005

The complex genetics of gait speed: genome-wide meta-analysis approach

scientific article published on 10 January 2017

The epigenetic clock is correlated with physical and cognitive fitness in the Lothian Birth Cohort 1936

scientific article

The stability of intelligence from age 11 to age 90 years: the Lothian birth cohort of 1921.

scientific article

Vascular risk factors and progression of white matter hyperintensities in the Lothian Birth Cohort 1936

scientific article

Vision and intelligence at age 83 in the Lothian Birth Cohort 1921

Weighted gene co-regulation network analysis (WGCNA) of promoter DNA methylation on all-cause mortality in old-aged birth cohorts finds modules of high-risk associated biomarkers

scientific article published on 10 March 2020

List of works by Alison Pattie

A study of common Mendelian disease carriers across ageing British cohorts: meta-analyses reveal heterozygosity for alpha 1-antitrypsin deficiency increases respiratory capacity and height

Age-dependent DNA methylation patterns on the Y chromosome in elderly males

Age-related gene expression changes, and transcriptome wide association study of physical and cognitive aging traits, in the Lothian Birth Cohort 1936.

An epigenetic predictor of death captures multi-modal measures of brain health

Apolipoprotein E genotype does not moderate the associations of depressive symptoms, neuroticism and allostatic load with cognitive ability and cognitive aging in the Lothian Birth Cohort 1936.

Apolipoprotein e gene variability and cognitive functions at age 79: a follow-up of the Scottish mental survey of 1932.

Archival sources for Sir Godfrey Hilton Thomson

Associations between education and brain structure at age 73 years, adjusted for age 11 IQ.

Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits

Associations of autozygosity with a broad range of human phenotypes

Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function ⬇️

Beyond a bigger brain: Multivariable structural brain imaging and intelligence

Brain Structural Differences Between 73- And 92-Year Olds Matched For Childhood Intelligence, Social Background, And Intracranial Volume

Brain cortical characteristics of lifetime cognitive ageing

Brain structural differences between 73- and 92-year olds matched for childhood intelligence, social background, and intracranial volume

Brain volumetric changes and cognitive ageing during the eighth decade of life

Carotid disease at age 73 and cognitive change from age 70 to 76 years: A longitudinal cohort study

Childhood intelligence in relation to major causes of death in 68 year follow-up: prospective population study

Cognitive change and the APOE epsilon 4 allele

Cognitive consequences of overweight and obesity in the ninth decade of life?

Cohort Profile Update: The Lothian Birth Cohorts of 1921 and 1936.

Cohort profile for the STratifying Resilience and Depression Longitudinally (STRADL) study: A depression-focused investigation of Generation Scotland, using detailed clinical, cognitive, and neuroimaging assessments

Cohort profile: the Lothian Birth Cohorts of 1921 and 1936.

Computational quantification of brain perivascular space morphologies: Associations with vascular risk factors and white matter hyperintensities. A study in the Lothian Birth Cohort 1936

Continued concern about nutritional supplements and cognitive function in the elderly

Correction: The complex genetics of gait speed: genome-wide meta-analysis approach

Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses

Coupled changes in brain white matter microstructure and fluid intelligence in later life

Coupled changes in hippocampal structure and cognitive ability in later life.

DNA methylation age of blood predicts all-cause mortality in later life

Diffusion tensor and magnetization transfer MRI measurements of periventricular white matter hyperintensities in old age.

Does cognitive ability predict mortality in the ninth decade? The Lothian Birth Cohort 1921

Does incipient dementia explain normal cognitive decline determinants? Lothian birth cohort 1921.

Early life characteristics and late life burden of cerebral small vessel disease in the Lothian Birth Cohort 1936.

Effect of smoking on physical and cognitive capability in later life: a multicohort study using observational and genetic approaches

Erratum: Corrigendum: Genetic variants associated with subjective well-being, depressive symptoms and neuroticism identified through genome-wide analyses

Exploratory analysis of age and sex dependent DNA methylation patterns on the X-chromosome in whole blood samples

Fluctuating asymmetry in brain structure and general intelligence in 73-year-olds

Fluid Intelligence Predicts Change in Depressive Symptoms in Later Life: The Lothian Birth Cohort 1936

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

Genetic analysis of over one million people identifies 535 novel loci for blood pressure

Genetic and environmental exposures constrain epigenetic drift over the human life course

Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses

Genome-wide analysis identifies 12 loci influencing human reproductive behavior

Genome-wide studies of verbal declarative memory in nondemented older people: the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium

Harmonization of Neuroticism and Extraversion phenotypes across inventories and cohorts in the Genetics of Personality Consortium: an application of Item Response Theory

Height and intelligence in the Lothian Birth Cohort 1921: a longitudinal study

Impact of small vessel disease in the brain on gait and balance

Interaction of APOE e4 and poor glycemic control predicts white matter hyperintensity growth from 73 to 76

Lack of association between polymorphisms in angiotensin-converting-enzyme and methylenetetrahydrofolate reductase genes and normal cognitive ageing in humans

Life long changes in cognitive ability are associated with prescribed medications in old age.

Life review in Scottish ninety year olds from the Lothian birth cohort 1921: Developing qualitative methodology in a longitudinal study

Life review in advanced age: qualitative research on the 'start in life' of 90-year-olds in the Lothian Birth Cohort 1921.

Lifecourse Activity Participation From Early, Mid, and Later Adulthood as Determinants of Cognitive Aging: The Lothian Birth Cohort 1921.

Lifetime intellectual function and satisfaction with life in old age: longitudinal cohort study.

Longitudinal telomere length shortening and cognitive and physical decline in later life: The Lothian Birth Cohorts 1936 and 1921.

Losing one's grip: a bivariate growth curve model of grip strength and nonverbal reasoning from age 79 to 87 years in the Lothian Birth Cohort 1921.

Mental ability in childhood and cognitive aging

More intelligent, more dependable children live longer: a 55-year longitudinal study of a representative sample of the Scottish nation

Neurology-related protein biomarkers are associated with cognitive ability and brain volume in older age

Ninety-nine independent genetic loci influencing general cognitive function include genes associated with brain health and structure (N = 280,360)

Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney

Oxidative stress, telomere length and biomarkers of physical aging in a cohort aged 79 years from the 1932 Scottish Mental Survey

Personality Polygenes, Positive Affect, and Life Satisfaction

Polygenic predictors of age-related decline in cognitive ability

Predictors of ageing-related decline across multiple cognitive functions

Predictors of gait speed and its change over three years in community-dwelling older people

Predictors of tooth loss in the 1921 Lothian Birth Cohort

Progression of White Matter Disease and Cortical Thinning Are Not Related in Older Community-Dwelling Subjects

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

Psychosocial factors and health as determinants of quality of life in community-dwelling older adults

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

Rare and low-frequency coding variants alter human adult height

Retinal microvascular network geometry and cognitive abilities in community-dwelling older people: The Lothian Birth Cohort 1936 study.

Retinal vascular image analysis as a potential screening tool for cerebrovascular disease: a rationale based on homology between cerebral and retinal microvasculatures.