List of works - René Lutter

A randomised controlled trial on the effect of inhaled hypertonic saline on quality of life in primary ciliary dyskinesia

scientific article published on 23 February 2017

Activation of the granzyme pathway in children with severe respiratory syncytial virus infection

scientific article published in June 2008

Addressing unmet needs in understanding asthma mechanisms: From the European Asthma Research and Innovation Partnership (EARIP) Work Package (WP)2 collaborators

scientific article

Age-Dependent Changes in the Pulmonary Renin-Angiotensin System Are Associated With Severity of Lung Injury in a Model of Acute Lung Injury in Rats

scientific article

Airway inflammation and mannitol challenge test in COPD.

scientific article

Arginine deficiency augments inflammatory mediator production by airway epithelial cells in vitro

scientific article

Bench-to-bedside review: bacterial pneumonia with influenza - pathogenesis and clinical implications

scientific article

Differential cytokine expression in skin after single and repeated irritation by sodium lauryl sulphate

scientific article

E1A expression dysregulates IL-8 production and suppresses IL-6 production by lung epithelial cells

scientific article

Effect of HIV and Chlamydia Infection on Rectal Inflammation and Cytokine Concentrations in Men Who Have Sex with Men ⬇️

scientific article published on July 31, 2013

Effect of dexamethasone on tracheal viral load and interleukin-8 tracheal concentration in children with respiratory syncytial virus infection

scientific article published in August 2003

Effect of oxidative stress on respiratory epithelium from children with Down syndrome ⬇️

scientific article published on November 22, 2012

Epithelial dysregulation in obese severe asthmatics with gastro-oesophageal reflux

scientific article published on 27 June 2019

Evaluation of coagulation activation after rhinovirus infection in patients with asthma and healthy control subjects: an observational study.

scientific article published on 07 February 2014

Expression of inhibitory regulators of innate immunity in patients with active tuberculosis

scientific article

Filaggrin loss-of-function mutations are associated with enhanced expression of IL-1 cytokines in the stratum corneum of patients with atopic dermatitis and in a murine model of filaggrin deficiency.

scientific article published on 8 February 2012

Glucocorticoid-induced changes in gene expression of airway smooth muscle in patients with asthma

scientific article

Granzyme A- and B-cluster deficiency delays acute lung injury in pneumovirus-infected mice

scientific article

HIV infection rather than concurrent opportunistic infections drives most systemic procoagulant, vascular and damage responses - a prospective cohort study in central Africa

scientific article published on 5 January 2017

Hemostatic Changes Associated With Increased Mortality Rates in Hospitalized Patients With HIV-Associated Tuberculosis: A Prospective Cohort Study

scientific article

IL-10 is an important mediator of the enhanced susceptibility to pneumococcal pneumonia after influenza infection

scientific article published in June 2004

IL-12 deficiency transiently improves viral clearance during the late phase of respiratory tract infection with influenza A virus in mice

scientific article published on 9 February 2006

IL-17 attenuates degradation of ARE-mRNAs by changing the cooperation between AU-binding proteins and microRNA16.

scientific article

Imbalance between pulmonary angiotensin-converting enzyme and angiotensin-converting enzyme 2 activity in acute respiratory distress syndrome

scientific article published on November 2013

Impact of HIV infection on the presentation, outcome and host response in patients admitted to the intensive care unit with sepsis; a case control study

scientific article published on 10 October 2016

Inflammation aggravates disease severity in Marfan syndrome patients.

scientific article

Inflammation and repeated infections in CGD: two sides of a coin

scientific article published on 15 November 2011

Influenza-induced expression of indoleamine 2,3-dioxygenase enhances interleukin-10 production and bacterial outgrowth during secondary pneumococcal pneumonia

scientific article published on 14 December 2005

Involvement of the platelet-activating factor receptor in host defense against Streptococcus pneumoniae during postinfluenza pneumonia

scientific article

Large-Scale Label-Free Quantitative Mapping of the Sputum Proteome

scientific article published on 8 May 2018

Mechanisms that potentially underlie virus-induced exaggerated inflammatory responses by airway epithelial cells.

scientific article

Mental quality of life is related to a cytokine genetic pathway

scientific article

Neutrophil extracellular traps cause airway obstruction during respiratory syncytial virus disease

scientific article published on 15 October 2015

Oxidative Stress: Promoter of Allergic Sensitization to Protease Allergens?

scientific article published on 23 May 2017

Pathway discovery using transcriptomic profiles in adult-onset severe asthma

scientific article

Plasma CC16 levels are associated with development of ALI/ARDS in patients with ventilator-associated pneumonia: a retrospective observational study

scientific article

Pneumovirus-Induced Lung Disease in Mice Is Independent of Neutrophil-Driven Inflammation

scientific article

Potential role of soluble TRAIL in epithelial injury in children with severe RSV infection.

scientific article

Publication bias in laboratory animal research: a survey on magnitude, drivers, consequences and potential solutions

scientific article

Pulmonary tuberculosis induces a systemic hypercoagulable state

scientific article published on 29 October 2014

Sputum proteomics and airway cell transcripts of current and ex-smokers with severe asthma in U-BIOPRED: an exploratory analysis.

scientific article published on 12 April 2018

Sputum transcriptomics reveal upregulation of IL-1 receptor family members in patients with severe asthma.

scientific article published on 17 May 2017

Stratification of asthma phenotypes by airway proteomic signatures

scientific article published on 28 March 2019

T-helper cell type 2 (Th2) and non-Th2 molecular phenotypes of asthma using sputum transcriptomics in U-BIOPRED.

scientific article

The Host Response in Patients with Sepsis Developing Intensive Care Unit-acquired Secondary Infections

scientific article published on 20 January 2017

The caspase inhibitor zVAD increases lung inflammation in pneumovirus infection in mice

scientific article

The effect of TIP on pneumovirus-induced pulmonary edema in mice

scientific article

Toll-like receptor 4 is not involved in host defense against respiratory tract infection with Sendai virus

scientific article published in October 2003

Tryptophan catabolism restricts IFN-γ-expressing neutrophils and Clostridium difficile immunopathology

scientific article

Twelve-Month Antiretroviral Therapy Suppresses Plasma and Genital Viral Loads but Fails to Alter Genital Levels of Cytokines, in a Cohort of HIV-Infected Rwandan Women

scientific article published on 26 May 2015

U-BIOPRED clinical adult asthma clusters linked to a subset of sputum omics

scientific article

Ventilator-induced inflammatory response in lipopolysaccharide-exposed rat lung is mediated by angiotensin-converting enzyme

scientific journal article

List of works by René Lutter

A randomised controlled trial on the effect of inhaled hypertonic saline on quality of life in primary ciliary dyskinesia

Activation of the granzyme pathway in children with severe respiratory syncytial virus infection

Addressing unmet needs in understanding asthma mechanisms: From the European Asthma Research and Innovation Partnership (EARIP) Work Package (WP)2 collaborators

Age-Dependent Changes in the Pulmonary Renin-Angiotensin System Are Associated With Severity of Lung Injury in a Model of Acute Lung Injury in Rats

Airway inflammation and mannitol challenge test in COPD.

Arginine deficiency augments inflammatory mediator production by airway epithelial cells in vitro

Bench-to-bedside review: bacterial pneumonia with influenza - pathogenesis and clinical implications

Differential cytokine expression in skin after single and repeated irritation by sodium lauryl sulphate

E1A expression dysregulates IL-8 production and suppresses IL-6 production by lung epithelial cells

Effect of HIV and Chlamydia Infection on Rectal Inflammation and Cytokine Concentrations in Men Who Have Sex with Men ⬇️

Effect of dexamethasone on tracheal viral load and interleukin-8 tracheal concentration in children with respiratory syncytial virus infection

Effect of oxidative stress on respiratory epithelium from children with Down syndrome ⬇️

Epithelial dysregulation in obese severe asthmatics with gastro-oesophageal reflux

Evaluation of coagulation activation after rhinovirus infection in patients with asthma and healthy control subjects: an observational study.

Expression of inhibitory regulators of innate immunity in patients with active tuberculosis

Filaggrin loss-of-function mutations are associated with enhanced expression of IL-1 cytokines in the stratum corneum of patients with atopic dermatitis and in a murine model of filaggrin deficiency.

Glucocorticoid-induced changes in gene expression of airway smooth muscle in patients with asthma

Granzyme A- and B-cluster deficiency delays acute lung injury in pneumovirus-infected mice

HIV infection rather than concurrent opportunistic infections drives most systemic procoagulant, vascular and damage responses - a prospective cohort study in central Africa

Hemostatic Changes Associated With Increased Mortality Rates in Hospitalized Patients With HIV-Associated Tuberculosis: A Prospective Cohort Study

IL-10 is an important mediator of the enhanced susceptibility to pneumococcal pneumonia after influenza infection

IL-12 deficiency transiently improves viral clearance during the late phase of respiratory tract infection with influenza A virus in mice

IL-17 attenuates degradation of ARE-mRNAs by changing the cooperation between AU-binding proteins and microRNA16.

Imbalance between pulmonary angiotensin-converting enzyme and angiotensin-converting enzyme 2 activity in acute respiratory distress syndrome

Impact of HIV infection on the presentation, outcome and host response in patients admitted to the intensive care unit with sepsis; a case control study

Inflammation aggravates disease severity in Marfan syndrome patients.

Inflammation and repeated infections in CGD: two sides of a coin

Influenza-induced expression of indoleamine 2,3-dioxygenase enhances interleukin-10 production and bacterial outgrowth during secondary pneumococcal pneumonia

Involvement of the platelet-activating factor receptor in host defense against Streptococcus pneumoniae during postinfluenza pneumonia

Large-Scale Label-Free Quantitative Mapping of the Sputum Proteome

Mechanisms that potentially underlie virus-induced exaggerated inflammatory responses by airway epithelial cells.

Mental quality of life is related to a cytokine genetic pathway

Neutrophil extracellular traps cause airway obstruction during respiratory syncytial virus disease

Oxidative Stress: Promoter of Allergic Sensitization to Protease Allergens?

Pathway discovery using transcriptomic profiles in adult-onset severe asthma

Plasma CC16 levels are associated with development of ALI/ARDS in patients with ventilator-associated pneumonia: a retrospective observational study

Pneumovirus-Induced Lung Disease in Mice Is Independent of Neutrophil-Driven Inflammation

Potential role of soluble TRAIL in epithelial injury in children with severe RSV infection.

Publication bias in laboratory animal research: a survey on magnitude, drivers, consequences and potential solutions

Pulmonary tuberculosis induces a systemic hypercoagulable state

Sputum proteomics and airway cell transcripts of current and ex-smokers with severe asthma in U-BIOPRED: an exploratory analysis.

Sputum transcriptomics reveal upregulation of IL-1 receptor family members in patients with severe asthma.

Stratification of asthma phenotypes by airway proteomic signatures

T-helper cell type 2 (Th2) and non-Th2 molecular phenotypes of asthma using sputum transcriptomics in U-BIOPRED.

The Host Response in Patients with Sepsis Developing Intensive Care Unit-acquired Secondary Infections

The caspase inhibitor zVAD increases lung inflammation in pneumovirus infection in mice

The effect of TIP on pneumovirus-induced pulmonary edema in mice

Toll-like receptor 4 is not involved in host defense against respiratory tract infection with Sendai virus

Tryptophan catabolism restricts IFN-γ-expressing neutrophils and Clostridium difficile immunopathology

Twelve-Month Antiretroviral Therapy Suppresses Plasma and Genital Viral Loads but Fails to Alter Genital Levels of Cytokines, in a Cohort of HIV-Infected Rwandan Women

U-BIOPRED clinical adult asthma clusters linked to a subset of sputum omics

Ventilator-induced inflammatory response in lipopolysaccharide-exposed rat lung is mediated by angiotensin-converting enzyme