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List of works by Leon H F Mullenders

32nd annual meeting of European Environmental Mutagen Society. DNA damage and repair fundamental aspects and contribution to human disorders

scientific article published in June 2003

3rd US-EU workshop: systems level understanding of DNA damage responses

scientific article

A PALB2-interacting domain in RNF168 couples homologous recombination to DNA break-induced chromatin ubiquitylation.

scientific article published on 27 February 2017

Antimony impairs nucleotide excision repair: XPA and XPE as potential molecular targets

scientific article

Blockage of transcription as a trigger for p53 accumulation by 2-acetylaminofluorene DNA-adducts

scientific article

Cellular concentrations of DDB2 regulate dynamic binding of DDB1 at UV-induced DNA damage

scientific article published on 20 October 2008

Clusters of transcription-coupled repair in the human genome

scientific article

Cockayne syndrome A and B proteins differentially regulate recruitment of chromatin remodeling and repair factors to stalled RNA polymerase II in vivo

scientific article

DDB2 promotes chromatin decondensation at UV-induced DNA damage

scientific article published on 9 April 2012

DNA damage response and transcription

scientific article

Deficient global genome repair of UV-induced cyclobutane pyrimidine dimers in terminally differentiated myocytes and proliferating fibroblasts from the rat heart

scientific article

Differential activity of UV-DDB in mouse keratinocytes and fibroblasts: impact on DNA repair and UV-induced skin cancer.

scientific article

Differential repair of the two major UV-induced photolesions in trichothiodystrophy fibroblasts.

scientific article published in February 2004

Dynamic in vivo interaction of DDB2 E3 ubiquitin ligase with UV-damaged DNA is independent of damage-recognition protein XPC.

scientific article

Elimination of keratinocytes stagnant in s-phase through epidermal turnover instead of in situ apoptosis

scientific article

Enhanced Nucleotide Excision Repair in Human Fibroblasts Pre‐exposed to Ionizing Radiation ⬇️

scientific article published on November 17, 2011

Epidermal stem and progenitor cells in murine epidermis accumulate UV damage despite NER proficiency

scientific article

Epidermal transit of replication-arrested, undifferentiated keratinocytes in UV-exposed XPC mice: an alternative to in situ apoptosis

scholarly article

Genotoxicity of soluble and particulate cadmium compounds: impact on oxidative DNA damage and nucleotide excision repair

scientific article

Global phosphoproteome profiling reveals unanticipated networks responsive to cisplatin treatment of embryonic stem cells

scientific article published on 17 October 2011

Heterochromatin protein 1 is recruited to various types of DNA damage.

scientific article published on May 2009

Impact of arsenic on nucleotide excision repair: XPC function, protein level, and gene expression

scientific article

Impaired repair of ionizing radiation-induced DNA damage in Cockayne syndrome cells

scientific article published on 07 February 2011

Increased DNA damage sensitivity of Cornelia de Lange syndrome cells: evidence for impaired recombinational repair

scientific article

Induction of nevi and skin tumors in Ink4a/Arf Xpa knockout mice by neonatal, intermittent, or chronic UVB exposures

scientific article published in March 2006

Insight in the multilevel regulation of NER.

scientific article

Lig4 and rad54 are required for repair of DNA double-strand breaks induced by P-element excision in Drosophila

scientific article

Microarray analysis of gene expression profiles of cardiac myocytes and fibroblasts after mechanical stress, ionising or ultraviolet radiation

scientific article

Mismatch repair protein Msh2 contributes to UVB-induced cell cycle arrest in epidermal and cultured mouse keratinocytes

scientific journal article

Molecular profiling of cutaneous squamous cell carcinomas and actinic keratoses from organ transplant recipients.

scientific article

Nucleotide excision repair and its interplay with transcription ⬇️

scientific article published on November 15, 2003

Nucleotide excision repair in differentiated cells

scientific article published on August 2006

Nucleotide excision repair of oxidised genomic DNA is not a source of urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine

scientific article

PARP1 promotes nucleotide excision repair through DDB2 stabilization and recruitment of ALC1

scientific article

Persistent transcription-blocking DNA lesions trigger somatic growth attenuation associated with longevity

scientific article published on 12 April 2009

Persistently stalled replication forks inhibit nucleotide excision repair in trans by sequestering Replication protein A.

scientific article

Pre-exposure to low doses: modulation of X-ray-induced dna damage and repair?

scientific article published in October 2005

Proteins of nucleotide and base excision repair pathways interact in mitochondria to protect from loss of subcutaneous fat, a hallmark of aging

scientific article

Reduced methylation-induced mutagenesis in rat splenocytes in vivo by sub-chronic low dose exposure to N-metyl-N-nitrosourea

scientific article

Repair characteristics and differentiation propensity of long-term cultures of epidermal keratinocytes derived from normal and NER-deficient mice

scientific article published on 22 September 2005

Repair of DNA lesions in chromosomal DNA impact of chromatin structure and Cockayne syndrome proteins

scientific article

Replication factor C recruits DNA polymerase delta to sites of nucleotide excision repair but is not required for PCNA recruitment

scientific article

Replication protein A safeguards genome integrity by controlling NER incision events ⬇️

scientific article published on 31 January 2011

Sealing of chromosomal DNA nicks during nucleotide excision repair requires XRCC1 and DNA ligase III alpha in a cell-cycle-specific manner

scientific article

Selective DNA damage responses in murine Xpa-/-, Xpc-/- and Csb-/- keratinocyte cultures

scientific article published on 22 September 2005

Separate domains of Rev1 mediate two modes of DNA damage bypass in mammalian cells

scientific article published on 30 March 2009

Site-specific analysis of UV-induced cyclobutane pyrimidine dimers in nucleotide excision repair-proficient and -deficient hamster cells: Lack of correlation with mutational spectra.

scientific article

Systems biology approach identifies the kinase Csnk1a1 as a regulator of the DNA damage response in embryonic stem cells

scientific article published on 22 January 2013

TRiC controls transcription resumption after UV damage by regulating Cockayne syndrome protein A.

scientific article published on 12 March 2018

The Drosophila melanogaster DNA Ligase IV gene plays a crucial role in the repair of radiation-induced DNA double-strand breaks and acts synergistically with Rad54

scientific article

The E3 ubiquitin ligase ARIH1 protects against genotoxic stress by initiating a 4EHP-mediated mRNA translation arrest.

scientific article

The UV-damaged DNA binding protein mediates efficient targeting of the nucleotide excision repair complex to UV-induced photo lesions.

scientific article

The cell-surface marker MTS24 identifies a novel population of follicular keratinocytes with characteristics of progenitor cells

scientific article

The core spliceosome as target and effector of non-canonical ATM signalling.

scientific article

The role of XPC: implications in cancer and oxidative DNA damage

scientific article

Three DNA polymerases, recruited by different mechanisms, carry out NER repair synthesis in human cells

scientific article

Touching base with PARPs: moonlighting in the repair of UV lesions and double-strand breaks

scientific article published on 04 April 2013

Transcription-coupled nucleotide excision repair in mammalian cells: molecular mechanisms and biological effects

scientific article published on January 2008

Transcription-coupled repair: impact on UV-induced mutagenesis in cultured rodent cells and mouse skin tumors

scientific article

Transcription-dependent cytosine deamination is a novel mechanism in ultraviolet light-induced mutagenesis

scientific article

UV-induced photolesions elicit ATR-kinase-dependent signaling in non-cycling cells through nucleotide excision repair-dependent and -independent pathways ⬇️

scientific article published on January 11, 2011

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