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List of works by Harry L.A. Janssen

Aberrant composition of the dendritic cell population in hepatic lymph nodes of patients with hepatocellular carcinoma

scientific article published in March 2006

Alpha-galactosylceramide in chronic hepatitis B infection: results from a randomized placebo-controlled Phase I/II trial.

scientific article published on January 2009

Analysis of intrahepatic HBV-specific cytotoxic T-cells during and after acute HBV infection in humans.

scientific article

Analysis of the transcriptome and immune function of monocytes during IFNα-based therapy in chronic HCV revealed induction of TLR7 responsiveness

scientific article published on 9 July 2014

Assessment of the effect of ribavirin on myeloid and plasmacytoid dendritic cells during interferon-based therapy of chronic hepatitis B patients

scientific article published on 20 July 2012

CD4+ CXCR5+ T cells in chronic HCV infection produce less IL-21, yet are efficient at supporting B cell responses

scientific article published on 2 October 2014

Clinical experience with α-galactosylceramide (KRN7000) in patients with advanced cancer and chronic hepatitis B/C infection.

scientific article published on 18 December 2010

Coarse vs. fine needle aspiration biopsy

Factors that predict response of patients with hepatitis B e antigen-positive chronic hepatitis B to peginterferon-alfa

scientific article published on 6 September 2009

Favorable effect of adefovir on the number and functionality of myeloid dendritic cells of patients with chronic HBV

scientific article published on 01 October 2006

Functional impairment of myeloid and plasmacytoid dendritic cells of patients with chronic hepatitis B.

scientific article published in September 2004

Gene expression profiling to predict and assess the consequences of therapy-induced virus eradication in chronic hepatitis C virus infection

scientific article

Hepatitis B Virus Lacks Immune Activating Capacity, but Actively Inhibits Plasmacytoid Dendritic Cell Function ⬇️

scientific article published on January 5, 2011

Hepatitis B Virus Surface Antigen Activates Myeloid Dendritic Cells via a Soluble CD14-Dependent Mechanism

scientific article published on 20 April 2016

Hepatitis B surface antigen quantification: why and how to use it in 2011 - a core group report

scientific article published on 28 June 2011

Hepatitis B virus surface antigen impairs myeloid dendritic cell function: a possible immune escape mechanism of hepatitis B virus

scientific article published on 28 June 2008

Human CD34-derived myeloid dendritic cell development requires intact phosphatidylinositol 3-kinase-protein kinase B-mammalian target of rapamycin signaling

scientific article published on 19 May 2010

Immunological Analysis During Interferon-Free Therapy for Chronic Hepatitis C Virus Infection Reveals Modulation of the Natural Killer Cell Compartment

scientific article published on 28 July 2015

Immunology of hepatitis B and hepatitis C virus infections.

scientific article published on January 2008

Induction of regulatory T-cells and interleukin-10-producing cells in non-responders to pegylated interferon-alpha therapy for chronic hepatitis B

scientific article published on 01 January 2007

Inflammatory monocytes recruited to the liver within 24 hours after virus-induced inflammation resemble Kupffer cells but are functionally distinct

scientific article

Inhibition of viral replication reduces regulatory T cells and enhances the antiviral immune response in chronic hepatitis B

scientific article published on 20 December 2006

Intrahepatic CD8 T-lymphocytes and HBV core expression in relation to response to antiviral therapy for chronic hepatitis B patients

scientific article published in February 2004

Intrahepatic CD8+ T-lymphocyte response is important for therapy-induced viral clearance in chronic hepatitis B infection

scientific article published on 25 April 2005

Intrahepatic natural killer cell activation, but not function, is associated with HBsAg levels in patients with HBeAg-negative chronic hepatitis B.

scientific article published on 25 July 2013

Intrahepatic regulatory T cells are phenotypically distinct from their peripheral counterparts in chronic HBV patients.

scientific article

Kupffer cells express a unique combination of phenotypic and functional characteristics compared with splenic and peritoneal macrophages.

scientific article

Kupffer cells interact with hepatitis B surface antigen in vivo and in vitro, leading to proinflammatory cytokine production and natural killer cell function.

scientific article published on 31 October 2014

Modulation of dendritic cell function by persistent viruses.

scientific article published on 25 September 2008

Monocytes from chronic HBV patients react in vitro to HBsAg and TLR by producing cytokines irrespective of stage of disease

scientific article

Natural killer cell activity and function in chronic HCV-infected patients during peg interferon and ribavirin: early effects of active substance use.

scientific article published on 2 January 2013

PI3K-PKB hyperactivation augments human plasmacytoid dendritic cell development and function.

scientific article

Polymorphisms Near IL28B and Serologic Response to Peginterferon in HBeAg-Positive Patients With Chronic Hepatitis B

article

Regulatory T cells contribute to the impaired immune response in patients with chronic hepatitis B virus infection.

scientific article published in April 2005

Response-guided peginterferon therapy in hepatitis B e antigen-positive chronic hepatitis B using serum hepatitis B surface antigen levels

scientific article published on 29 July 2013

Restoration of TLR3-activated myeloid dendritic cell activity leads to improved natural killer cell function in chronic hepatitis B virus infection

scientific article published on 8 February 2012

Similar frequencies, phenotype and activation status of intrahepatic NK cells in chronic HBV patients after long-term treatment with tenofovir disoproxil fumarate (TDF).

scientific article

The Effect of Chronic Hepatitis B Virus Infection on BDCA3+ Dendritic Cell Frequency and Function.

scientific article

The mannose receptor acts as hepatitis B virus surface antigen receptor mediating interaction with intrahepatic dendritic cells

scientific article

Tight Control of STAT5 Activity Determines Human CD34-Derived Interstitial Dendritic Cell and Langerhans Cell Development ⬇️

scientific article published on May 20, 2011

Tumor necrosis factor alpha inhibits the suppressive effect of regulatory T cells on the hepatitis B virus-specific immune response

scientific article

Unique intrahepatic transcriptomics profiles discriminate the clinical phases of a chronic HBV infection.

scientific article

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