List of works - László Hackler

A novel pleiotropic effect of aspirin: Beneficial regulation of pro- and anti-inflammatory mechanisms in microglial cells

scientific article published on 17 May 2017

AUTEN-67, an autophagy-enhancing drug candidate with potent antiaging and neuroprotective effects

scientific article (publication date: 2016)

Achiral Mannich-Base Curcumin Analogs Induce Unfolded Protein Response and Mitochondrial Membrane Depolarization in PANC-1 Cells.

scientific article published on 7 October 2017

Alternative splicing of neuroligin and its protein distribution in the outer plexiform layer of the chicken retina.

scientific article

BEST1 expression in the retinal pigment epithelium is modulated by OTX family members

scientific article

Capsaicin-sensitive sensory neurons regulate myocardial function and gene expression pattern of rat hearts: a DNA microarray study

scientific article published on 8 November 2005

Cell-specific DNA methylation patterns of retina-specific genes

scientific article

Cholesterol diet-induced hyperlipidemia influences gene expression pattern of rat hearts: a DNA microarray study

scientific article published in March 2004

Cleavage of the human thyrotropin receptor by ADAM10 is regulated by thyrotropin.

scientific article published on September 2007

Combination of unsaturated fatty acids and ionizing radiation on human glioma cells: cellular, biochemical and gene expression analysis.

scientific article published on 2 September 2014

Computational analysis of tissue-specific gene networks: application to murine retinal functional studies.

scientific article

Development of chemically modified glass surfaces for nucleic acid, protein and small molecule microarrays

scientific article published on January 2003

Different mechanisms influencing permeation of PDGF-AA and PDGF-BB across the blood-brain barrier

scientific article published in October 2003

Dynamic usage of alternative splicing exons during mouse retina development

scientific article

Dynamics of regulatory networks in the developing mouse retina.

scientific article

Effect of classic preconditioning on the gene expression pattern of rat hearts: a DNA microarray study

scientific article published in February 2003

Enantioselective Synthesis of 8-Hydroxyquinoline Derivative, Q134 as a Hypoxic Adaptation Inducing Agent

scientific article published on 23 November 2019

Endomorphin analog analgesics with reduced abuse liability, respiratory depression, motor impairment, tolerance, and glial activation relative to morphine

scientific article (publication date: June 2016)

Functional genomic screening identifies dual leucine zipper kinase as a key mediator of retinal ganglion cell death

scientific article published on 19 February 2013

Gene and protein expression changes in response to normoxic perfusion in mouse hearts.

scientific article

Gene expression and molecular composition of phospholipids in rat brain in relation to dietary n-6 to n-3 fatty acid ratio.

scientific article

Gene expression dynamics in deer antler: mesenchymal differentiation toward chondrogenesis

scientific article published on 5 December 2006

Imidazo[1,2-]pyrazole-7-carboxamides Induce Apoptosis in Human Leukemia Cells at Nanomolar Concentrations

scientific article published in November 2018

Lipid droplet binding thalidomide analogs activate endoplasmic reticulum stress and suppress hepatocellular carcinoma in a chemically induced transgenic mouse model

scientific article

Lipidomic analysis reveals a radiosensitizing role of gamma-linolenic acid in glioma cells

scientific article

Mannich Curcuminoids as Potent Anticancer Agents.

scientific article published on 26 May 2017

MicroRNA profile of the developing mouse retina.

scientific article

Modification by docosahexaenoic acid of age-induced alterations in gene expression and molecular composition of rat brain phospholipids

scientific article

Mutation in the βA3/A1-crystallin gene impairs phagosome degradation in the retinal pigmented epithelium of the rat.

scientific article

N-arylurethane neighboring group participation during solvolysis of 3-methoxy-17-N-phenylcarbamoyloxy-16-p_tolylsulfonyloxymethylestra-1,3,5(10)-triene stereoisomers

Neighboring group participation. Part 15. Stereoselective synthesis of some steroidal tetrahydrooxazin-2-ones, as novel presumed inhibitors of human 5alpha-reductase

scientific article published in July 2004

New molecular methods for classification, diagnosis and therapy prediction of hematological malignancies

scientific article

New synthesis of steroidal tetrahydrooxazin-2-ones

Novel peptide-peptide cooperation may transform feeding behavior

scientific article published in December 2002

Novel real-time cell analysis platform for the dynamic monitoring of ionizing radiation effects on human tumor cell lines and primary fibroblasts

scientific article

RNA amplification results in reproducible microarray data with slight ratio bias

scientific article

Recovery of cyanine-dye nucleotide triphosphates

scientific article

Ring expansion of steroid oxethans into hihydrooxazines

Steroids. Part 43. Thermal decomposition of steroidal azidoformates

Synthesis and Cytoprotective Characterization of 8-Hydroxyquinoline Betti Products

scientific article published on 02 August 2018

Synthesis, cytotoxic characterization, and SAR study of imidazo[1,2-b]pyrazole-7-carboxamides

scientific article published on 10 June 2018

The Curcumin Analog C-150, Influencing NF-κB, UPR and Akt/Notch Pathways Has Potent Anticancer Activity In Vitro and In Vivo

scientific article

The proteasome inhibitor MG132 protects against acute pancreatitis.

scientific article

The role of n-3 polyunsaturated fatty acids in brain: modulation of rat brain gene expression by dietary n-3 fatty acids

scientific article

The small molecule AUTEN-99 (autophagy enhancer-99) prevents the progression of neurodegenerative symptoms.

scientific article

Transcript identification and profiling during salt stress and recovery of Populus euphratica.

scientific article published on March 2004

Triosephosphate isomerase deficiency: consequences of an inherited mutation at mRNA, protein and metabolic levels

scientific article published on December 2005

Tyramide Signal Amplification for Antibody-Overlay Lectin Microarray: A Strategy to Improve the Sensitivity of Targeted Glycan Profiling ⬇️

scientific article published on January 4, 2011

Use of laser capture microdissection for analysis of retinal mRNA/miRNA expression and DNA methylation

scientific article

betaA3/A1-crystallin in astroglial cells regulates retinal vascular remodeling during development

scientific journal article

List of works by László Hackler

A novel pleiotropic effect of aspirin: Beneficial regulation of pro- and anti-inflammatory mechanisms in microglial cells

AUTEN-67, an autophagy-enhancing drug candidate with potent antiaging and neuroprotective effects

Achiral Mannich-Base Curcumin Analogs Induce Unfolded Protein Response and Mitochondrial Membrane Depolarization in PANC-1 Cells.

Alternative splicing of neuroligin and its protein distribution in the outer plexiform layer of the chicken retina.

BEST1 expression in the retinal pigment epithelium is modulated by OTX family members

Capsaicin-sensitive sensory neurons regulate myocardial function and gene expression pattern of rat hearts: a DNA microarray study

Cell-specific DNA methylation patterns of retina-specific genes

Cholesterol diet-induced hyperlipidemia influences gene expression pattern of rat hearts: a DNA microarray study

Cleavage of the human thyrotropin receptor by ADAM10 is regulated by thyrotropin.

Combination of unsaturated fatty acids and ionizing radiation on human glioma cells: cellular, biochemical and gene expression analysis.

Computational analysis of tissue-specific gene networks: application to murine retinal functional studies.

Development of chemically modified glass surfaces for nucleic acid, protein and small molecule microarrays

Different mechanisms influencing permeation of PDGF-AA and PDGF-BB across the blood-brain barrier

Dynamic usage of alternative splicing exons during mouse retina development

Dynamics of regulatory networks in the developing mouse retina.

Effect of classic preconditioning on the gene expression pattern of rat hearts: a DNA microarray study

Enantioselective Synthesis of 8-Hydroxyquinoline Derivative, Q134 as a Hypoxic Adaptation Inducing Agent

Endomorphin analog analgesics with reduced abuse liability, respiratory depression, motor impairment, tolerance, and glial activation relative to morphine

Functional genomic screening identifies dual leucine zipper kinase as a key mediator of retinal ganglion cell death

Gene and protein expression changes in response to normoxic perfusion in mouse hearts.

Gene expression and molecular composition of phospholipids in rat brain in relation to dietary n-6 to n-3 fatty acid ratio.

Gene expression dynamics in deer antler: mesenchymal differentiation toward chondrogenesis

Imidazo[1,2-]pyrazole-7-carboxamides Induce Apoptosis in Human Leukemia Cells at Nanomolar Concentrations

Lipid droplet binding thalidomide analogs activate endoplasmic reticulum stress and suppress hepatocellular carcinoma in a chemically induced transgenic mouse model

Lipidomic analysis reveals a radiosensitizing role of gamma-linolenic acid in glioma cells

Mannich Curcuminoids as Potent Anticancer Agents.

MicroRNA profile of the developing mouse retina.

Modification by docosahexaenoic acid of age-induced alterations in gene expression and molecular composition of rat brain phospholipids

Mutation in the βA3/A1-crystallin gene impairs phagosome degradation in the retinal pigmented epithelium of the rat.

N-arylurethane neighboring group participation during solvolysis of 3-methoxy-17-N-phenylcarbamoyloxy-16-p_tolylsulfonyloxymethylestra-1,3,5(10)-triene stereoisomers

Neighboring group participation. Part 15. Stereoselective synthesis of some steroidal tetrahydrooxazin-2-ones, as novel presumed inhibitors of human 5alpha-reductase

New molecular methods for classification, diagnosis and therapy prediction of hematological malignancies

New synthesis of steroidal tetrahydrooxazin-2-ones

Novel peptide-peptide cooperation may transform feeding behavior

Novel real-time cell analysis platform for the dynamic monitoring of ionizing radiation effects on human tumor cell lines and primary fibroblasts

RNA amplification results in reproducible microarray data with slight ratio bias

Recovery of cyanine-dye nucleotide triphosphates

Ring expansion of steroid oxethans into hihydrooxazines

Steroids. Part 43. Thermal decomposition of steroidal azidoformates

Synthesis and Cytoprotective Characterization of 8-Hydroxyquinoline Betti Products

Synthesis, cytotoxic characterization, and SAR study of imidazo[1,2-b]pyrazole-7-carboxamides

The Curcumin Analog C-150, Influencing NF-κB, UPR and Akt/Notch Pathways Has Potent Anticancer Activity In Vitro and In Vivo

The proteasome inhibitor MG132 protects against acute pancreatitis.

The role of n-3 polyunsaturated fatty acids in brain: modulation of rat brain gene expression by dietary n-3 fatty acids

The small molecule AUTEN-99 (autophagy enhancer-99) prevents the progression of neurodegenerative symptoms.

Transcript identification and profiling during salt stress and recovery of Populus euphratica.

Triosephosphate isomerase deficiency: consequences of an inherited mutation at mRNA, protein and metabolic levels

Tyramide Signal Amplification for Antibody-Overlay Lectin Microarray: A Strategy to Improve the Sensitivity of Targeted Glycan Profiling ⬇️

Use of laser capture microdissection for analysis of retinal mRNA/miRNA expression and DNA methylation

betaA3/A1-crystallin in astroglial cells regulates retinal vascular remodeling during development