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List of works by Martijn Fenaux

A Cyclic Phosphoramidate Prodrug of 2'-deoxy-2'-fluoro-2'-C-methylguanosine for the Treatment of Dengue Infection

scientific article published on 21 September 2020

Active viremia in rotavirus-infected mice.

scientific article

Antiviral Nucleotide Incorporation by Recombinant Human Mitochondrial RNA Polymerase Is Predictive of Increased In Vivo Mitochondrial Toxicity Risk.

scientific article published on 19 September 2016

Discovery of GS-9669, a thumb site II non-nucleoside inhibitor of NS5B for the treatment of genotype 1 chronic hepatitis C infection

scientific article published on 6 November 2013

Discovery of a 2'-fluoro-2'-C-methyl C-nucleotide HCV polymerase inhibitor and a phosphoramidate prodrug with favorable properties

scientific article published on 20 February 2017

Discovery of the first C-nucleoside HCV polymerase inhibitor (GS-6620) with demonstrated antiviral response in HCV infected patients.

scientific article

Inhibition of hepatitis C virus replication by GS-6620, a potent C-nucleoside monophosphate prodrug.

scientific article published on 13 January 2014

Mechanistic characterization of GS-9190 (Tegobuvir), a novel nonnucleoside inhibitor of hepatitis C virus NS5B polymerase

scientific article

Novel mutations in a tissue culture-adapted hepatitis C virus strain improve infectious-virus stability and markedly enhance infection kinetics

scientific article published on 2 February 2011

Nucleotide Prodrug Containing a Nonproteinogenic Amino Acid To Improve Oral Delivery of a Hepatitis C Virus Treatment

scholarly article by Joy Y Feng et al published August 2018 in Antimicrobial Agents and Chemotherapy

Preclinical characterization of GS-9669, a thumb site II inhibitor of the hepatitis C virus NS5B polymerase

scientific article published on 26 November 2012

Preparation and biological evaluation of 1'-cyano-2'-C-methyl pyrimidine nucleosides as HCV NS5B polymerase inhibitors

scientific article published on 22 May 2014

Quantitative Evaluation of Rotaviral Antigenemia in Children with Acute Rotaviral Diarrhea

scientific article published in 2006

Selective Thyroid Hormone Receptor β Agonists with Oxadiazolone Acid Isosteres

scientific article published on 05 August 2020

Structural and regulatory elements of HCV NS5B polymerase--β-loop and C-terminal tail--are required for activity of allosteric thumb site II inhibitors

scientific article published on 9 January 2014

Structure-activity relationship of uridine-based nucleoside phosphoramidate prodrugs for inhibition of dengue virus RNA-dependent RNA polymerase

scholarly article by Gang Wang et al published 15 July 2018 in Bioorganic & Medicinal Chemistry Letters

Synthesis and characterization of 1'-C-cyano-2'-fluoro-2'-C-methyl pyrimidine nucleosides as HCV polymerase inhibitors.

scientific article

The Race to Bash NASH: Emerging Targets and Drug Development in a Complex Liver Disease

scientific article published on 29 January 2020

Tri-substituted acylhydrazines as tertiary amide bioisosteres: HCV NS5B polymerase inhibitors ⬇️

scientific article published on May 17, 2012

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