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List of works by Michael Mertzman

Discovery of GS-9256: A novel phosphinic acid derived inhibitor of the hepatitis C virus NS3/4A protease with potent clinical activity ⬇️

scientific article published on December 13, 2011

Discovery of GS-9669, a thumb site II non-nucleoside inhibitor of NS5B for the treatment of genotype 1 chronic hepatitis C infection

scientific article published on 6 November 2013

Discovery of a JAK1/3 Inhibitor and Use of a Prodrug To Demonstrate Efficacy in a Model of Rheumatoid Arthritis ⬇️

scientific article published on 13 February 2019

Identification of N-Methyl Nicotinamide and N-Methyl Pyridazine-3-Carboxamide Pseudokinase Domain Ligands as Highly Selective Allosteric Inhibitors of Tyrosine Kinase 2 (TYK2)

scientific article published on 17 July 2019

Identification of RIPK3 Type II Inhibitors Using High-Throughput Mechanistic Studies in Hit Triage

scientific article published on 06 May 2019

Novel, potent, and orally bioavailable phosphinic acid inhibitors of the hepatitis C virus NS3 protease ⬇️

scientific article published on May 3, 2011

Optimization of Pharmacokinetics through Manipulation of Physicochemical Properties in a Series of HCV Inhibitors

scientific article published on 8 August 2011

Organic chemistry. Practical olefin hydroamination with nitroarenes

scientific article

Preclinical characterization of GS-9669, a thumb site II inhibitor of the hepatitis C virus NS5B polymerase

scientific article published on 26 November 2012

Use of benzofuran for concomitant protection of aldehyde and phenol groups in the preparation of mycophenolic acid analogues

scientific article

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