List of works - Willard Lew - Paulina

List of works by Willard Lew

2-Aminobenzimidazoles as potent Aurora kinase inhibitors.

scientific article

Design and synthesis of 2-amino-isoxazolopyridines as Polo-like kinase inhibitors

scientific article

Design and synthesis of 2-amino-pyrazolopyridines as Polo-like kinase 1 inhibitors

scientific article

Discovery and Synthesis of a Phosphoramidate Prodrug of a Pyrrolo[2,1-f][triazin-4-amino] Adenine C-Nucleoside (GS-5734) for the Treatment of Ebola and Emerging Viruses

scientific article published on 26 January 2017

Discovery of GS-9669, a Thumb Site II Non-Nucleoside Inhibitor of NS5B for the Treatment of Genotype 1 Chronic Hepatitis C Infection ⬇️

scientific article published on November 6, 2013

Discovery of a 2'-fluoro-2'-C-methyl C-nucleotide HCV polymerase inhibitor and a phosphoramidate prodrug with favorable properties

scientific article published on 20 February 2017

Discovery of a potent and selective aurora kinase inhibitor

scientific article

Discovery of the first C-nucleoside HCV polymerase inhibitor (GS-6620) with demonstrated antiviral response in HCV infected patients.

scientific article

Identification of potent and novel small-molecule inhibitors of caspase-3

scientific article published on 01 November 2003

Identification of potent and selective small-molecule inhibitors of caspase-3 through the use of extended tethering and structure-based drug design

scientific article published in November 2002

Practical Total Synthesis of the Anti-Influenza Drug GS-4104

scientific article (publication date: June 1998)

Preclinical characterization of GS-9669, a thumb site II inhibitor of the hepatitis C virus NS5B polymerase

scientific article published on 26 November 2012

Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys

scientific article

Water-soluble prodrugs of an Aurora kinase inhibitor

scientific article published on 19 January 2009

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