List of works - Nancy E Brutsche

A Randomized, placebo-controlled, crossover pilot trial of the oral selective NR2B antagonist MK-0657 in patients with treatment-resistant major depressive disorder

scientific article

A randomized add-on trial of an N-methyl-D-aspartate antagonist in treatment-resistant bipolar depression

scientific article

A randomized trial of a low-trapping nonselective N-methyl-D-aspartate channel blocker in major depression

scientific article

Acute stress symptoms do not worsen in posttraumatic stress disorder and abuse with a single subanesthetic dose of ketamine

scientific article published on 13 December 2012

Anhedonia as a clinical correlate of suicidal thoughts in clinical ketamine trials.

scientific article published on 25 April 2017

Are 24-hour motor activity patterns associated with continued rapid response to ketamine?

scientific article published on 16 October 2018

Assessing measures of suicidal ideation in clinical trials with a rapid-acting antidepressant.

scientific article published on 16 June 2015

Baseline delta sleep ratio predicts acute ketamine mood response in major depressive disorder ⬇️

scientific article published on August 5, 2012

Brain-derived neurotrophic factor Val66Met polymorphism and antidepressant efficacy of ketamine in depressed patients.

scientific article published on 06 July 2012

Brain-derived neurotrophic factor and initial antidepressant response to an N-methyl-D-aspartate antagonist.

scientific article

Clinical predictors of ketamine response in treatment-resistant major depression

scientific article

Concomitant BDNF and sleep slow wave changes indicate ketamine-induced plasticity in major depressive disorder

scientific article

Course of improvement in depressive symptoms to a single intravenous infusion of ketamine vs add-on riluzole: results from a 4-week, double-blind, placebo-controlled study

scientific article published in February 2012

D-serine plasma concentration is a potential biomarker of (R,S)-ketamine antidepressant response in subjects with treatment-resistant depression

scientific article

Do the dissociative side effects of ketamine mediate its antidepressant effects?

scientific article

Effect of baseline anxious depression on initial and sustained antidepressant response to ketamine.

scientific article published on September 2014

Family history of alcohol dependence and antidepressant response to an N‐methyl‐D‐aspartate antagonist in bipolar depression ⬇️

scientific article published on September 14, 2012

Family history of alcohol dependence and initial antidepressant response to an N-methyl-D-aspartate antagonist

scientific article

Features of dissociation differentially predict antidepressant response to ketamine in treatment-resistant depression.

scientific article published on 17 February 2018

Improvement in suicidal ideation after ketamine infusion: relationship to reductions in depression and anxiety.

scientific article

Ketamine has distinct electrophysiological and behavioral effects in depressed and healthy subjects

scientific article published on 27 February 2018

Ketamine's antidepressant efficacy is extended for at least four weeks in subjects with a family history of an alcohol use disorder.

scientific article

Lithium and Valproate Levels Do Not Correlate with Ketamine's Antidepressant Efficacy in Treatment-Resistant Bipolar Depression

scientific article published on 7 June 2015

Motor-Activity Markers of Circadian Timekeeping Are Related to Ketamine's Rapid Antidepressant Properties

scientific article published on 28 March 2017

Neural correlates of rapid antidepressant response to ketamine in bipolar disorder.

scientific article published on 18 September 2013

Neural correlates of rapid antidepressant response to ketamine in treatment-resistant unipolar depression: a preliminary positron emission tomography study.

scientific article published on 27 March 2013

Rapid resolution of suicidal ideation after a single infusion of an N-methyl-D-aspartate antagonist in patients with treatment-resistant major depressive disorder

scientific article

Rating depression over brief time intervals with the Hamilton Depression Rating Scale: standard vs. abbreviated scales

scientific article

Relationship of ketamine's plasma metabolites with response, diagnosis, and side effects in major depression

scientific article

Replication of ketamine's antidepressant efficacy in bipolar depression: a randomized controlled add-on trial

scientific article

Riluzole likely lacks antidepressant efficacy in ketamine non-responders.

scientific article

Simultaneous population pharmacokinetic modelling of ketamine and three major metabolites in patients with treatment-resistant bipolar depression

scientific article published on August 2012

Synaptic Potentiation Is Critical for Rapid Antidepressant Response to Ketamine in Treatment-Resistant Major Depression ⬇️

scientific article published on April 21, 2012

The antidepressant efficacy of subanesthetic-dose ketamine does not correlate with baseline subcortical volumes in a replication sample with major depressive disorder.

scientific article

List of works by Nancy E Brutsche

A Randomized, placebo-controlled, crossover pilot trial of the oral selective NR2B antagonist MK-0657 in patients with treatment-resistant major depressive disorder

A randomized add-on trial of an N-methyl-D-aspartate antagonist in treatment-resistant bipolar depression

A randomized trial of a low-trapping nonselective N-methyl-D-aspartate channel blocker in major depression

Acute stress symptoms do not worsen in posttraumatic stress disorder and abuse with a single subanesthetic dose of ketamine

Anhedonia as a clinical correlate of suicidal thoughts in clinical ketamine trials.

Are 24-hour motor activity patterns associated with continued rapid response to ketamine?

Assessing measures of suicidal ideation in clinical trials with a rapid-acting antidepressant.

Baseline delta sleep ratio predicts acute ketamine mood response in major depressive disorder ⬇️

Brain-derived neurotrophic factor Val66Met polymorphism and antidepressant efficacy of ketamine in depressed patients.

Brain-derived neurotrophic factor and initial antidepressant response to an N-methyl-D-aspartate antagonist.

Clinical predictors of ketamine response in treatment-resistant major depression

Concomitant BDNF and sleep slow wave changes indicate ketamine-induced plasticity in major depressive disorder

Course of improvement in depressive symptoms to a single intravenous infusion of ketamine vs add-on riluzole: results from a 4-week, double-blind, placebo-controlled study

D-serine plasma concentration is a potential biomarker of (R,S)-ketamine antidepressant response in subjects with treatment-resistant depression

Do the dissociative side effects of ketamine mediate its antidepressant effects?

Effect of baseline anxious depression on initial and sustained antidepressant response to ketamine.

Family history of alcohol dependence and antidepressant response to an N‐methyl‐D‐aspartate antagonist in bipolar depression ⬇️

Family history of alcohol dependence and initial antidepressant response to an N-methyl-D-aspartate antagonist

Features of dissociation differentially predict antidepressant response to ketamine in treatment-resistant depression.

Improvement in suicidal ideation after ketamine infusion: relationship to reductions in depression and anxiety.

Ketamine has distinct electrophysiological and behavioral effects in depressed and healthy subjects

Ketamine's antidepressant efficacy is extended for at least four weeks in subjects with a family history of an alcohol use disorder.

Lithium and Valproate Levels Do Not Correlate with Ketamine's Antidepressant Efficacy in Treatment-Resistant Bipolar Depression

Motor-Activity Markers of Circadian Timekeeping Are Related to Ketamine's Rapid Antidepressant Properties

Neural correlates of rapid antidepressant response to ketamine in bipolar disorder.

Neural correlates of rapid antidepressant response to ketamine in treatment-resistant unipolar depression: a preliminary positron emission tomography study.

Rapid resolution of suicidal ideation after a single infusion of an N-methyl-D-aspartate antagonist in patients with treatment-resistant major depressive disorder

Rating depression over brief time intervals with the Hamilton Depression Rating Scale: standard vs. abbreviated scales

Relationship of ketamine's plasma metabolites with response, diagnosis, and side effects in major depression

Replication of ketamine's antidepressant efficacy in bipolar depression: a randomized controlled add-on trial

Riluzole likely lacks antidepressant efficacy in ketamine non-responders.

Simultaneous population pharmacokinetic modelling of ketamine and three major metabolites in patients with treatment-resistant bipolar depression

Synaptic Potentiation Is Critical for Rapid Antidepressant Response to Ketamine in Treatment-Resistant Major Depression ⬇️

The antidepressant efficacy of subanesthetic-dose ketamine does not correlate with baseline subcortical volumes in a replication sample with major depressive disorder.