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List of works by Carlos A Zarate Jr

A Randomized Trial of a Low-Trapping Nonselective N-Methyl-D-Aspartate Channel Blocker in Major Depression ⬇️

scientific article published on August 15, 2013

A Randomized, placebo-controlled, crossover pilot trial of the oral selective NR2B antagonist MK-0657 in patients with treatment-resistant major depressive disorder

scientific article

A randomized add-on trial of an N-methyl-D-aspartate antagonist in treatment-resistant bipolar depression

scientific article

A randomized, placebo-controlled pilot trial of the delta opioid receptor agonist AZD2327 in anxious depression.

scientific article published on 04 January 2016

A single infusion of ketamine improves depression scores in patients with anxious bipolar depression

scientific article published on 14 November 2014

Abnormal hippocampal functioning and impaired spatial navigation in depressed individuals: evidence from whole-head magnetoencephalography

scientific article

Acute stress symptoms do not worsen in posttraumatic stress disorder and abuse with a single subanesthetic dose of ketamine

scientific article published on 13 December 2012

Amygdala volume in depressed patients with bipolar disorder assessed using high resolution 3T MRI: the impact of medication

scientific article

An investigation of amino-acid neurotransmitters as potential predictors of clinical improvement to ketamine in depression

scientific article published in November 2011

An open-label trial of riluzole in patients with treatment-resistant major depression

scientific article

Anhedonia as a clinical correlate of suicidal thoughts in clinical ketamine trials.

scientific article published on 25 April 2017

Assessing measures of suicidal ideation in clinical trials with a rapid-acting antidepressant.

scientific article published on 16 June 2015

Baseline delta sleep ratio predicts acute ketamine mood response in major depressive disorder ⬇️

scientific article published on August 5, 2012

Baseline working memory activation deficits in dimensional anxious depression as detected by magnetoencephalography ⬇️

scientific article published on 20 January 2015

Biomarkers in mood disorders research: developing new and improved therapeutics

scientific article published on January 2014

Brain-derived neurotrophic factor Val66Met polymorphism and antidepressant efficacy of ketamine in depressed patients.

scientific article published on 06 July 2012

Brain-derived neurotrophic factor and initial antidepressant response to an N-methyl-D-aspartate antagonist.

scientific article

Clinical predictors of ketamine response in treatment-resistant major depression

scientific article

Concomitant BDNF and sleep slow wave changes indicate ketamine-induced plasticity in major depressive disorder

scientific article

Course of improvement in depressive symptoms to a single intravenous infusion of ketamine vs add-on riluzole: results from a 4-week, double-blind, placebo-controlled study

scientific article published in February 2012

D-serine plasma concentration is a potential biomarker of (R,S)-ketamine antidepressant response in subjects with treatment-resistant depression

scientific article

Default Mode Connectivity in Major Depressive Disorder Measured Up to 10 Days After Ketamine Administration

scholarly article by Jennifer W Evans et al published 15 October 2018 in Biological Psychiatry

Defining anxious depression: a review of the literature.

scientific article published on 14 March 2013

Developing biomarkers in mood disorders research through the use of rapid-acting antidepressants

scientific article

Do the dissociative side effects of ketamine mediate its antidepressant effects?

scientific article

Effect of baseline anxious depression on initial and sustained antidepressant response to ketamine.

scientific article published on September 2014

Efficacy of a protein kinase C inhibitor (tamoxifen) in the treatment of acute mania: a pilot study

scientific article

Family history of alcohol dependence and antidepressant response to an N‐methyl‐D‐aspartate antagonist in bipolar depression ⬇️

scientific article published on September 14, 2012

Family history of alcohol dependence and initial antidepressant response to an N-methyl-D-aspartate antagonist

scientific article

Features of dissociation differentially predict antidepressant response to ketamine in treatment-resistant depression.

scientific article published on 17 February 2018

Glutamate and its receptors in the pathophysiology and treatment of major depressive disorder

scientific article

Glutamatergic modulators: the future of treating mood disorders?

scientific article

Histone deacetylases and mood disorders: epigenetic programming in gene-environment interactions

scientific article

Improvement in suicidal ideation after ketamine infusion: relationship to reductions in depression and anxiety.

scientific article

Increased fear-potentiated startle in major depressive disorder patients with lifetime history of suicide attempt

scientific article

Ketamine's antidepressant efficacy is extended for at least four weeks in subjects with a family history of an alcohol use disorder.

scientific article

Lithium and Valproate Levels Do Not Correlate with Ketamine's Antidepressant Efficacy in Treatment-Resistant Bipolar Depression

scientific article published on 7 June 2015

Major depression is not associated with blunting of aversive responses; evidence for enhanced anxious anticipation

scientific article

Motor-Activity Markers of Circadian Timekeeping Are Related to Ketamine's Rapid Antidepressant Properties

scientific article published on 28 March 2017

NEUROBIOLOGICAL ASPECTS OF SUICIDE AND SUICIDE ATTEMPTS IN BIPOLAR DISORDER.

scientific article published on June 2013

Neural correlates of rapid antidepressant response to ketamine in bipolar disorder.

scientific article published on 18 September 2013

Neural correlates of rapid antidepressant response to ketamine in treatment-resistant unipolar depression: a preliminary positron emission tomography study.

scientific article published on 27 March 2013

Neurobiology of anxious depression: a review

scientific article

New therapeutic targets for mood disorders

scientific article (publication date: 13 April 2010)

Novel glutamatergic agents for major depressive disorder and bipolar disorder

scientific article published on 25 September 2011

Novel insights into lithium's mechanism of action: neurotrophic and neuroprotective effects

scientific article

Pharmacologic treatment of dimensional anxious depression: a review

scientific article

Pramipexole for bipolar II depression: a placebo-controlled proof of concept study

scientific article

Protein kinase C inhibitors: rationale for use and potential in the treatment of bipolar disorder

scientific article

Rapid antidepressant changes with sleep deprivation in major depressive disorder are associated with changes in vascular endothelial growth factor (VEGF): a pilot study

scientific article

Rapid decrease in depressive symptoms with an N-methyl-d-aspartate antagonist in ECT-resistant major depression

scientific article

Rapid resolution of suicidal ideation after a single infusion of an N-methyl-D-aspartate antagonist in patients with treatment-resistant major depressive disorder

scientific article

Rating depression over brief time intervals with the Hamilton Depression Rating Scale: standard vs. abbreviated scales

scientific article

Recognition of emotional facial expressions in anxious and nonanxious depression.

scientific article published on 14 June 2016

Relationship of ketamine's plasma metabolites with response, diagnosis, and side effects in major depression

scientific article

Replication of ketamine's antidepressant efficacy in bipolar depression: a randomized controlled add-on trial

scientific article

Riluzole likely lacks antidepressant efficacy in ketamine non-responders.

scientific article

Second messenger/signal transduction pathways in major mood disorders: moving from membrane to mechanism of action, part I: major depressive disorder.

scientific article published on 05 March 2013

Second messenger/signal transduction pathways in major mood disorders: moving from membrane to mechanism of action, part II: bipolar disorder

scientific article

Simultaneous population pharmacokinetic modelling of ketamine and three major metabolites in patients with treatment-resistant bipolar depression

scientific article published on August 2012

Subanesthetic dose ketamine does not induce an affective switch in three independent samples of treatment-resistant major depression

scientific article published on 28 May 2013

Synaptic Potentiation Is Critical for Rapid Antidepressant Response to Ketamine in Treatment-Resistant Major Depression ⬇️

scientific article published on April 21, 2012

Targeting glutamatergic signaling for the development of novel therapeutics for mood disorders

scientific article published on January 2009

The McLean-Harvard First-Episode Mania Study: Prediction of Recovery and First Recurrence

scientific article

The Neurobiology of the Switch Process in Bipolar Disorder

scientific article

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