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List of works by Jude E. Uzonna

Altered proinflammatory cytokine production and enhanced resistance to Trypanosoma congolense infection in lymphotoxin beta-deficient mice

scientific article published in August 2009

CD4+CD25+ regulatory T cells attenuate lipopolysaccharide-induced systemic inflammatory responses and promotes survival in murine Escherichia coli infection

scientific article published in July 2013

CD8+ T cells are preferentially activated during primary low dose leishmania major infection but are completely dispensable during secondary anti-Leishmania immunity

scientific article

Control of New World cutaneous leishmaniasis is IL-12 independent but STAT4 dependent

scientific article published in November 2002

Deficiency of CD40 Reveals an Important Role for LIGHT in Anti-Leishmania Immunity

scientific article published on 29 May 2015

Deficiency of Leishmania phosphoglycans influences the magnitude but does not affect the quality of secondary (memory) anti-Leishmania immunity

scientific article

Deficiency of Phosphatidylinositol 3-Kinase δ Signaling Leads to Diminished Numbers of Regulatory T Cells and Increased Neutrophil Activity Resulting in Mortality Due to Endotoxic Shock

scientific article

Deficiency of p110δ isoform of the phosphoinositide 3 kinase leads to enhanced resistance to Leishmania donovani

scientific article (publication date: June 2014)

Deficiency of prolactin-inducible protein leads to impaired Th1 immune response and susceptibility to Leishmania major in mice

scientific article published on 12 February 2015

Diminazene Aceturate (Berenil) Modulates the Host Cellular and Inflammatory Responses to Trypanosoma congolense Infection ⬇️

scientific article published on November 7, 2012

Diminazene aceturate (Berenil), a new use for an old compound?

scientific article published on 02 June 2014

Elevated antigen-driven IL-9 responses are prominent in peanut allergic humans

scientific article

Hepatic stellate cells regulate liver immunity to visceral leishmaniasis through P110δ-dependent induction and expansion of regulatory T cells in mice.

scientific article published on 20 August 2015

Host Intracellular Signaling Events and Pro-inflammatory Cytokine Production in African Trypanosomiasis

scientific article

Identification of broadly conserved cross-species protective Leishmania antigen and its responding CD4+ T cells.

scientific article

Immunity to visceral leishmaniasis: implications for immunotherapy

scientific article

Immunization with persistent attenuated Delta lpg2 Leishmania major parasites requires adjuvant to provide protective immunity in C57BL/6 mice

scientific article

Immunotherapy as a strategy for treatment of leishmaniasis: a review of the literature.

scientific article published on September 2009

In Search of a Cure for Sepsis: Taming the Monster in Critical Care Medicine.

scientific article

Infection with arginase-deficient Leishmania major reveals a parasite number-dependent and cytokine-independent regulation of host cellular arginase activity and disease pathogenesis

scientific article

Inoculation of killed Leishmania major into immune mice rapidly disrupts immunity to a secondary challenge via IL-10-mediated process.

scientific article published on 06 August 2009

Interaction of Macrophage Antigen 1 and CD40 Ligand Leads to IL-12 Production and Resistance in CD40-Deficient Mice Infected with Leishmania major.

scientific article published on 24 August 2015

Interleukin-17-Mediated Control of Parasitemia in Experimental Trypanosoma congolense Infection in Mice ⬇️

scientific article published on September 20, 2010

Invariant NKT cells preferentially modulate the function of CD8 alpha+ dendritic cell subset in inducing type 1 immunity against infection

scientific article published on 20 January 2010

LIGHT Is critical for IL-12 production by dendritic cells, optimal CD4+ Th1 cell response, and resistance to Leishmania major

scientific journal article

Leishmania major phosphoglycans influence the host early immune response by modulating dendritic cell functions

scientific article published on June 2009

Low dose Leishmania major promotes a transient T helper cell type 2 response that is down-regulated by interferon gamma-producing CD8+ T cells

scientific article

Low-dose intradermal infection with trypanosoma congolense leads to expansion of regulatory T cells and enhanced susceptibility to reinfection

scientific article published on 16 December 2013

Molecular regulation of Trypanosoma congolense-induced nitric oxide production in macrophages

scientific article

Parasite-derived arginase influences secondary anti-Leishmania immunity by regulating programmed cell death-1-mediated CD4+ T cell exhaustion.

scientific article published on 04 March 2013

Pathways leading to interleukin-12 production and protective immunity in cutaneous leishmaniasis

scientific article published on 29 June 2016

Persistent parasites and immunologic memory in cutaneous leishmaniasis: implications for vaccine designs and vaccination strategies.

scientific article published on January 2008

Pharmacological inhibition of p110δ subunit of PI3K confers protection against experimental leishmaniasis

scientific article published on 20 December 2016

Prolactin-Inducible Protein: From Breast Cancer Biomarker to Immune Modulator-Novel Insights from Knockout Mice

scientific article published on 7 September 2016

Protective immunity and vaccination against cutaneous leishmaniasis.

scientific article published on 29 May 2012

Qualitative differences in the early immune response to live and killed Leishmania major: Implications for vaccination strategies against Leishmaniasis

scientific article

Regulatory T cells enhance susceptibility to experimental Trypanosoma congolense infection independent of mouse genetic background

scientific article

Regulatory T cells restrain CD4+ T cells from causing unregulated immune activation and hypersensitivity to lipopolysaccharide challenge

scientific article

Semaphorin 3E Alleviates Hallmarks of House Dust Mite-Induced Allergic Airway Disease

scientific article published on July 2017

Semaphorin 3E Regulates the Response of Macrophages to Lipopolysaccharide-Induced Systemic Inflammation

scientific article published on 27 November 2019

Social and Economic Burden of Human Leishmaniasis

scientific article published on 19 January 2016

The B cell adaptor molecule Bam32 is critically important for optimal antibody response and resistance to Trypanosoma congolense infection in mice

scientific article

The development of effector and memory T cells in cutaneous leishmaniasis: the implications for vaccine development.

scientific article published in October 2004

The early interaction of Leishmania with macrophages and dendritic cells and its influence on the host immune response

scientific article

The human breast cancer-associated protein, the prolactin-inducible protein (PIP), regulates intracellular signaling events and cytokine production by macrophages.

scientific article

The p110 delta isoform of phosphatidylinositol 3-kinase controls the quality of secondary anti-Leishmania immunity by regulating expansion and effector function of memory T cell subsets

scientific article published on 12 February 2010

Vaccines and vaccination strategies against human cutaneous leishmaniasis

scientific article published on 12 May 2009

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