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List of works by Timur M. Yusufzai

Annealing helicase 2 (AH2), a DNA-rewinding motor with an HNH motif

scientific article published on November 15, 2010

Annealing helicase HARP closes RPA-stabilized DNA bubbles non-processively

scientific article

Biochemical analysis of histone deacetylase-independent transcriptional repression by MeCP2

scientific article published on 24 January 2013

Both CTCF-dependent and -independent insulators are found between the mouse T cell receptor alpha and Dad1 genes

scientific article

Branching out with DNA helicases

scientific article published on February 15, 2011

CTCF tethers an insulator to subnuclear sites, suggesting shared insulator mechanisms across species

scientific article (publication date: 30 January 2004)

HARP is an ATP-driven annealing helicase

scientific article

HARP preferentially co-purifies with RPA bound to DNA-PK and blocks RPA phosphorylation

scientific article

HMGN proteins act in opposition to ATP-dependent chromatin remodeling factors to restrict nucleosome mobility.

scientific article published on June 2009

Homologous-recombination-deficient tumours are dependent on Polθ-mediated repair

scientific article

Human CHD1 is required for early DNA-damage signaling and is uniquely regulated by its N terminus.

scientific article published on 26 February 2018

Human CHD2 is a chromatin assembly ATPase regulated by its chromo- and DNA-binding domains

scientific article

Inhibiting the oncogenic translation program is an effective therapeutic strategy in multiple myeloma.

scientific article

Introducing rare diseases

scientific article published on 18 April 2013

NEIL3 Repairs Telomere Damage during S Phase to Secure Chromosome Segregation at Mitosis

scientific article published on August 2017

The 5'-HS4 chicken beta-globin insulator is a CTCF-dependent nuclear matrix-associated element

scholarly article

The ATP-dependent chromatin remodeling enzymes CHD6, CHD7, and CHD8 exhibit distinct nucleosome binding and remodeling activities

scientific article

The annealing helicase HARP is recruited to DNA repair sites via an interaction with RPA

scientific article

The chromatin remodeling factor CHD5 is a transcriptional repressor of WEE1.

scientific article

The tumor suppressor chromodomain helicase DNA-binding protein 5 (CHD5) remodels nucleosomes by unwrapping

scientific article

USF1 recruits histone modification complexes and is critical for maintenance of a chromatin barrier

scientific article

USP1 Is Required for Replication Fork Protection in BRCA1-Deficient Tumors

scientific article published on 01 December 2018