List of works - Detlev Ganten

151 years Berliner Klinische Wochenschrift and the 20th anniversary of the Journal of Molecular Medicine

scientific article published on 11 August 2015

2-[N-[(S)-1-ethoxycarbonyl-3-phenylpropyl]-L-alanyl]-(1S,3S,5S)-2- azabicyclo[3.3.0]octane-3-carboxylic acid (Hoe 498): antihypertensive action and persistent inhibition of tissue converting enzyme activity in spontaneously hypertensive rats

scientific article published on January 1, 1984

A Novel Orally Active Converting-Enzyme Inhibitor Ys 980: Effects on Blood Pressure in Spontaneously Hypertensive Rats ⬇️

scientific article published on December 1, 1979

A SNP map of the rat genome generated from cDNA sequences

scientific article

A micromethod for the measurement of renin in brain nuclei: Its application in spontaneously hypertensive rats ⬇️

scientific article published on May 1, 1982

A transgenic rat expressing human APP with the Swedish Alzheimer's disease mutation

scientific article

Academic medicine must take its global role: the M8 Alliance of Academic Health Centers and Medical Universities ⬇️

scientific article published on October 9, 2010

Actions of angiotensin and lisinopril on thalamic somatosensory neurons in normotensive, non-transgenic and hypertensive, transgenic rats

scientific article published in October 1997

Activation of the renin-angiotensin system in heart failure and hypertrophy--studies in human hearts and transgenic rats

scientific article

Acute effects of cyclooxygenase-2 inhibition on renal function in heterozygous ren-2-transgenic rats on normal or low sodium intake

scientific article

Acute sino-aortic denervation in rats produces a selective increase of adrenaline turnover in the dorsal midline area of the caudal medulla oblongata and a reduction of adrenaline levels in the anterior and posterior hypothalamus

scientific article published on January 1981

Adrenal renin is released into the circulation of the hypertensive transgenic rat TGR (mRen-2)27

scientific article published on 01 January 1992

Alpha atrial natriuretic peptide concentrations in plasma of children with congenital heart and pulmonary diseases.

scientific article

Alterations in blood pressure and heart rate variability in transgenic rats with low brain angiotensinogen

scientific article published in February 2001

Alterations in sympathetic ganglionic transmission in response to angiotensin II in (mRen2)27 transgenic rats

scientific article published on 19 January 2004

Alterations of cardiac alpha- and beta-adrenoceptors and inotropic responsiveness in hypertensive transgenic rats harbouring the mouse renin gene (TGR(mREN2)27)

scientific article published on 01 May 1995

Alterations of the renin-angiotensin system at the RVLM of transgenic rats with low brain angiotensinogen

scientific article

Altered angiotensinogen amino acid sequence and plasma angiotensin II levels in genetically hypertensive rats. A study on cause and effect

scientific article published on 01 August 1995

Altered neuropeptide concentrations in spontaneously hypertensive rats: cause or consequence?

scientific article

Alternative splicing of the mRNA coding for the human endothelial angiotensin-converting enzyme: a new mechanism for solubilization

scientific article published in June 1998

Aminergic and peptidergic pathways in the nervous system with special reference to the hypothalamus

scientific article published on January 1, 1978

An old couple: the renin–angiotensin system (RAS) and the Journal of Molecular Medicine (JMolMed)

Androgen dependence and tissue specificity of renin messenger RNA expression in mice

scientific article published on 01 January 1990

Angiotensin I converting enzyme and chymase in cardiovascular tissues.

scientific article

Angiotensin II (AT(1)) receptor blockade reduces vascular tissue factor in angiotensin II-induced cardiac vasculopathy

scientific article published on July 2000

Angiotensin II AT1-receptor blockade inhibits monocyte activation and adherence in transgenic (mRen2)27 rats

scientific article published on 01 March 1999

Angiotensin II controls angiotensinogen secretion at a pretranslational level

scientific article published in December 1988

Angiotensin II immunoreactive pathways in the central nervous system of the rat: evidence for a projection from the subfornical organ to the paraventricular nucleus of the hypothalamus

scientific article published on 01 January 1984

Angiotensin II immunoreactivity in the neural afferents and efferents of the subfornical organ of the rat.

scientific article published in November 1984

Angiotensin II induced inflammation in the kidney and in the heart of double transgenic rats

scientific article

Angiotensin II induces connective tissue growth factor gene expression via calcineurin-dependent pathways

scientific article published on July 2003

Angiotensin II receptor blockade in TGR(mREN2)27: effects of renin-angiotensin-system gene expression and cardiovascular functions

article

Angiotensin and cell growth: a link to cardiovascular hypertrophy?

scientific article published on 01 January 1991

Angiotensin biosynthesis and concentrations in brain of normotensive and hypertensive rats

scientific article published on January 1, 1984

Angiotensin formation in the isolated rat hindlimb

scientific article published on 01 October 1989

Angiotensin peptides acting at rostral ventrolateral medulla contribute to hypertension of TGR(mREN2)27 rats

article

Angiotensin stimulates oxytocin release ⬇️

scientific article published on 01 October 1981

Angiotensin stimulates oxytocin release: impaired response in rats with genetic hypothalamic diabetes insipidus

scientific article published on 01 January 1982

Angiotensin stimulates oxytocin release: imparied response in rats with genetic hypothalamic diabetes insipidus

scientific article published on 01 September 1982

Angiotensin stimulates β-endorphin release from anterior pituitary gland cell cultures of rats ⬇️

scientific article published on April 20, 1984

Angiotensin synthesis in the brain and increased turnover in hypertensive rats

scientific article published in August 1983

Angiotensin-(1-7) and baroreflex function in nucleus tractus solitarii of (mRen2)27 transgenic rats

scientific article published on June 2008

Angiotensin-converting enzyme inhibition and AT1 receptor blockade modify the pressure-natriuresis relationship by additive mechanisms in rats with human renin and angiotensinogen genes.

scientific article published in August 1999

Angiotensin-converting enzyme-independent pathways of angiotensin II formation in human tissues and cardiovascular diseases

scientific article published on January 1996

Angiotensin-forming enzyme in brain tissue

scientific article published in July 1971

Angiotensin-induced hypertension in the rat. Sympathetic nerve activity and prostaglandins

scientific article

Angiotensin-like activity in resistance vessels. Immunocytochemical study in Chinese hamsters.

scientific article

Angiotensinogen concentrations and renin clearance : implications for blood pressure regulation

scientific article published on 01 March 2000

Angiotensinogen gene expression in extrahepatic rat tissues: application of a solution hybridization assay

scientific article published on 01 September 1988

Angiotensinogen is cleaved to angiotensin in isolated rat blood vessels

scientific article published on 01 June 1993

Angiotensinogen mRNA and pressor reactions to angiotensin in brain stem areas of spontaneously hypertensive rats

scientific article published in July 1993

Angiotensinogen messenger RNA stabilization by angiotensin II.

scientific article

Antihypertensive Effects of the Novel Converting-Enzyme Inhibitor YS 980 in Spontaneously Hypertensive Rats ⬇️

scientific article published on January 1, 1981

Antihypertensive action and inhibition of tissue conversion enzyme by ramipril, perindopril and enalapril in the spontaneously hypertensive rat (SHRSP)

scientific article published on June 1986

Antihypertensive action and inhibition of tissue converting enzyme (CE) by three prodrug CE inhibitors, enalapril, ramipril and perindopril in stroke-prone spontaneously hypertensive rats

scientific article published on October 1986

Antihypertensive action of the converting enzyme inhibitor perindopril (S9490-3) in spontaneously hypertensive rats: comparison with enalapril (MK421) and ramipril (Hoe498).

scientific article published in March 1986

Antihypertensive effect of the GABA receptor agonist muscimol in spontaneously hypertensive rats. Role of the sympathoadrenal axis

scientific article published in January 1984

Antisense oligonucleotide to c-fos induces ipsilateral rotational behaviour to d-amphetamine.

scientific article published in December 1993

Aspects of molecular biology and biochemistry of the cardiac renin-angiotensin system

scientific article published on January 1989

Aspirin inhibits NF-kappaB and protects from angiotensin II-induced organ damage

scientific article (publication date: August 2001)

Assignment of the kinin receptor B1 and B2 genes (Bdkrb1 and Bdkrb2) to rat chromosome 6q3.2 by FISH and radiation hybrid mapping

article

Association and cosegregation of stroke with impaired endothelium-dependent vasorelaxation in stroke prone, spontaneously hypertensive rats.

scientific article published on July 1996

Atrial natriuretic factor determinations and chronic sodium homeostasis

scientific article published on 01 May 1986

Atrial natriuretic factor in sodium-sensitive and sodium-resistant Dahl rats

scientific article published on February 1987

Atrial natriuretic factor—a circulating hormone stimulated by volume loading

scientific article published in Nature

Atrial natriuretic peptide and volume changes in children

scientific article published on 01 January 1986

Atrial natriuretic peptide: a new factor in blood pressure control

scientific article

Atrial natriuretic peptides in brain nuclei of rats with inherited diabetes insipidus (Brattleboro rats).

scientific article published in June 1990

Atriopeptin III kinetics and pharmacodynamics in normal and anephric rats

scientific article published on 01 February 1986

Augmented agonist-induced Ca(2+)-sensitization of coronary artery contraction in genetically hypertensive rats. Evidence for altered signal transduction in the coronary smooth muscle cells

scientific article published on October 1994

Autoradiographic localization of mas proto-oncogene mRNA in adult rat brain using in situ hybridization

scientific article published in July 1990

Baroreceptor reflex regulation in anesthetized transgenic rats with low glia-derived angiotensinogen

scientific article published on 3 November 2006

Basic fibroblast growth factor expression and tenascin C immunoreactivity after partial unilateral hemitransection of the rat brain

scientific article published in August 1996

Basic methodology in the molecular characterization of genes

scientific article

Beta-adrenergic neuroeffector mechanisms in cardiac hypertrophy of renin transgenic rats

scientific article published on 01 December 1994

Blockade of endothelin receptors attenuates end-organ damage in homozygous hypertensive ren-2 transgenic rats

scientific article

Blood Pressure Effects of Endogenous Brain Angiotensin in Rats are Increased by Inhibition of Prostaglandin Biosynthesis ⬇️

scientific article published on December 1, 1979

Blood Pressure and Heart Rate Responses to Centrally Administered Substance P Are Increased in Spontaneously Hypertensive Rats ⬇️

scientific article published on 01 December 1980

Blood pressure reduction and diabetes insipidus in transgenic rats deficient in brain angiotensinogen

scientific article

Blood pressure, electrolyte and adrenal responses in swim-trained hypertensive rats

scientific article published on 01 April 1987

Blood pressure-independent effects in rats with human renin and angiotensinogen genes.

scientific article

Brain angiotensin II stimulates release of pituitary hormones, plasma catecholamines and increases blood pressure in dogs

scientific article published on 01 December 1980

Brain angiotensin II: localization and possible functions

scientific article published on January 1987

Brain angiotensin: on the way to becoming a well-studied neuropeptide system ⬇️

scientific article published on November 15, 1984

Brain angiotensin: pathways and pharmacology

scientific article published on June 1988

Brain converting enzyme inhibition: a possible mechanism for the antihypertensive action of captopril in spontaneously hypertensive rats

scientific article published on 01 April 1981

Brain peptides and blood pressure control.

scientific article published in January 1987

Brain peptides and the regulation of blood pressure

scientific article published on 01 July 1983

Building Bridges through Science.

scientific article published in November 2017

Cardiac angiotensin II formation: the angiotensin-I converting enzyme and human chymase.

scientific article published on November 1993

Cardiac angiotensin II receptors: studies on functional coupling in Sprague-Dawley rats and TGR(αMHC-hAT1) transgenic rats ⬇️

scientific article published on 01 July 1997

Cardiac angiotensinogen and its local activation in the isolated perfused beating heart

scientific article published on 01 September 1990

Cardiac renin-angiotensin system

scientific article

Cardiorenal consequences of dual angiotensin converting enzyme and neutral endopeptidase 24.11 inhibition in transgenic rats with an extra renin gene

scientific article published on 01 September 1996

Cardiovascular and renal effects of atrial natriuretic factor

scientific article

Catecholamine turnover changes in hypothalamus and dorsal midline area of the caudal medulla oblongata of spontaneously hypertensive rats

scientific article published on 01 December 1979

Cellular expression of angiotensin type-1 receptor mRNA in the kidney

scientific article published on 01 August 1993

Cellular localization of angiotensin type 1 receptor and angiotensinogen mRNAs in the subfornical organ of the rat brain

scientific article published in February 1993

Central blood pressure effects of substance P and angiotensin II: role of the sympathetic nervous system and vasopressin

scientific article published on 01 April 1981

Central catecholamine-neuropeptide Y interactions at the pre- and postsynaptic level in cardiovascular centers

scientific article published in January 1987

Central depletion of angiotensinogen is associated with elevated AT1 receptors in the SFO and PVN

scientific article published on 01 January 2004

Central peptidergic stimulation in blood pressure control: role of enkephalins in rats

scientific article published on 01 December 1981

Central pressor actions of angiotensin II.

scientific article published in January 1976

Cerivastatin prevents angiotensin II-induced renal injury independent of blood pressure- and cholesterol-lowering effects

Changes in the central ANF-system of renovascular hypertensive rats

scientific article published on 01 January 1991

Changes of blood pressure and aortic strip contractile responses to ET-1 of heterozygous female transgenic rats, TGR(mRen2)27.

scientific article published in March 1998

Characterization of rat intestinal anglotensin II receptors ⬇️

scientific article published on 01 November 1991

Chromosomal mapping of quantitative trait loci contributing to stroke in a rat model of complex human disease

scientific article published on August 1996

Chronic dexamethasone treatment suppresses hypertension development in the transgenic rat TGR(mREN2)27

article

Chronic endothelin receptor blockade reduces end-organ damage independently of blood pressure effects in salt-loaded heterozygous Ren-2 transgenic rats

scientific article published in January 2004

Chronic estrogen treatment in female transgenic (mRen2)27 hypertensive rats augments endothelium-derived nitric oxide release

scientific article published on 01 June 1997

Chronic hypertension changes myosin isoenzyme pattern and decreases myosin phosphorylation in the rat heart

scientific article published on 01 October 1988

Chronic immunoneutralization of brain angiotensin-(1-12) lowers blood pressure in transgenic (mRen2)27 hypertensive rats

scientific article published on 29 April 2009

Chymase-dependent angiotensin II forming systems in humans

scientific article

Circadian blood pressure variation in transgenic hypertensive rats

scientific article published on 01 July 1993

Coexistence of renin and angiotensin II in epitheloid cell secretory granules of rat kidney

scientific article published on 01 January 1984

Combined high-performance liquid chromatography-radioimmunoassay for the characterization and quantitative measurement of neuropeptides

scientific article published on 01 November 1984

Comparison between PMSG- and FSH-induced superovulation for the generation of transgenic rats.

scientific article published in October 2002

Comparison of angiotensin II staining in rat brain using affinity purified and crude antisera

scientific article published in January 1987

Comparisons of effects of Hoe-498 and enalapril in isolated guinea pig hearts and rat myocardium

scientific article published in June 1985

Components of the renin-angiotensin system in the cerebrospinal fluid of rats and dogs with special consideration of the origin and the fate of angiotensin II

scientific article published on 01 November 1980

Congenic strains confirm the presence of salt-sensitivity QTLs on chromosome 1 in the Sabra rat model of hypertension

scientific article published on 15 January 2003

Congenic substitution mapping excludes Sa as a candidate gene locus for a blood pressure quantitative trait locus on rat chromosome 1.

scientific article published in October 1999

Conserved synteny in rat and mouse for a blood pressure QTL on human chromosome 17

scientific article published on 01 June 2002

Contribution of a 12 kDa protein to the angiotensin II-induced stabilization of angiotensinogen mRNA: interaction with the 3' untranslated mRNA

scientific article published on 01 April 1995

Contribution of local renin-angiotensin system to cardiac hypertrophy, phenotypic modulation, and remodeling in TGR (mRen2)27 transgenic rats

scientific article published on 01 August 1996

Converting enzyme inhibition specifically prevents the development and induces regression of cardiac hypertrophy in rats

scientific article

Converting enzyme inhibitors and their effects on the renin-angiotensin system of the blood vessel wall

scientific article published on January 1989

Converting enzyme inhibitors differentially affect expression of genes of the renin-angiotensin system

scientific article published on 01 April 1995

Converting-enzyme in the choroid plexus, brain, and kidney: Immunocytochemical and biochemical studies in rats ⬇️

scientific article published on March 10, 1981

Cyclosporin A protects against angiotensin II-induced end-organ damage in double transgenic rats harboring human renin and angiotensinogen genes

scientific article published on 01 January 2000

DNA fingerprinting of spontaneously hypertensive and Wistar-Kyoto rats: implications for hypertension research

scientific article published on 01 October 1989

Decreased renal haemodynamic response to inhibition of nitric oxide synthase in subtotally nephrectomized rats.

scientific article published in June 1995

Defective suppression of the aldosterone biosynthesis during stroke permissive diet in the stroke-prone phenotype of the spontaneously hypertensive rat

scientific article published on 01 April 2000

Demonstration of renin mRNA, angiotensinogen mRNA, and angiotensin converting enzyme mRNA expression in the human eye: evidence for an intraocular renin-angiotensin system

scientific article published on February 1996

Depressor role of angiotensin AT2 receptors in the (mRen-2)27 transgenic rat

scientific article published on 01 March 1998

Detection of vasopressin mRNA in the neurointermediate lobe of the rat pituitary

scientific article published in October 1990

Development of a new strain of spontaneously hypertensive rats homozygous for hypothalamic diabetes insipidus

scientific article published on 01 March 1983

Development of parthenogenetic rat embryos

scientific article published in March 2003

Development, genotype and phenotype of a new colony of the Sabra hypertension prone (SBH/y) and resistant (SBN/y) rat model of salt sensitivity and resistance

scientific article published on 01 October 1996

Dietary salt excess unmasks blunted aldosterone suppression and sodium retention in the stroke-prone phenotype of the spontaneously hypertensive rat

scientific article published on 01 August 1993

Differences in Rat Kidney Morphology between Males, Females and Testosterone-Treated Females ⬇️

scientific article published on May 1, 1991

Different antagonist potency of saralasin in acute and chronic angiotensin-dependent hypertension

scientific article published on 01 September 1983

Differential Gene Expression of Renin and Angiotensinogen in the TGR(mREN-2)27 Transgenic Rat

article

Differential actions of neuronal and hormonal vasopressin on blood pressure and baroreceptor reflex sensitivity in rats

scientific article published in January 1986

Differential effects of angiotensin II and angiotensin-(1-7) at the nucleus tractus solitarii of transgenic rats with low brain angiotensinogen

scientific article

Differential effects of central angiotensin II and substance P on sympathetic nerve activity in conscious rats. Implications for cardiovascular adaptation to behavioral responses

scientific article published in April 1985

Differential modulation of the baroreceptor reflex by brain and plasma vasopressin

scientific article published on June 1986

Differential regulation of beta-endorphin in the anterior pituitary, intermediate lobe, hypothalamus and brain stem

scientific article published in January 1983

Differential regulation of central vasopressin in transgenic rats harboring the mouse Ren-2 gene

scientific article published on 01 September 1994

Differential regulation of central vasopressin receptors in transgenic rats with low brain angiotensinogen

scientific article

Differential regulation of vascular angiotensin I-converting enzyme in hypertension.

scientific article published in September 1994

Dissection of a quantitative trait locus for genetic hypertension on rat chromosome 10.

scientific article

Dissociation between in vivo and in vitro measurements of converting enzyme activity after chronic oral treatment with captopril in rats ⬇️

scientific article published on April 21, 1982

Distribution of neuropeptide immunoreactive nerve terminals within the subnuclei of the nucleus of the tractus solitarius of the rat ⬇️

scientific article published on January 20, 1984

Distribution of neurophysin II immunoreactive nerve fibers within the subnuclei of the nucleus of the tractus solitarius of the rat.

scientific article published on October 1984

Distribution of neurophysins in rat brain: radioimmunological measurement and characterization

scientific article published in June 1982

Dose effects of human renin in rats transgenic for human angiotensinogen

scientific article published on 01 April 1997

Dual pathway for angiotensin II formation in human internal mammary arteries

scientific article

Dual peroxidase and colloidal gold-labeling study of angiotensin converting enzyme and angiotensin-like immunoreactivity in the rat subfornical organ

scientific article

Effect of Saralasin and atropine on thirst induced by water deprivation

scientific article published on January 1, 1977

Effect of adrenal arterial infusion of different Mg 2+ concentrations on the spontaneous release of catecholamines in the anesthetized dog.

scientific article published in May 1973

Effect of atrial natriuretic peptide (ANP) on the renal kallikrein-kinin system in normotensive and spontaneously hypertensive rats

scientific article published on 01 January 1988

Effect of beta-adrenoceptor blockade on the cardiovascular and hyperglycaemic actions of diazoxide ⬇️

scientific article published on May 1, 1978

Effect of bosentan on NF-kappaB, inflammation, and tissue factor in angiotensin II-induced end-organ damage

scientific article published on 01 August 2000

Effect of converting enzyme inhibitors on tissue converting enzyme and angiotensin II: therapeutic implications

scientific article published on 01 April 1987

Effect of denervation on the leucine-enkephalin content of the adrenal gland of spontaneously hypertensive rats (SHRSP)

scientific article published on 01 January 1984

Effect of estrogen on neprilysin expression in uterus and kidney of Sprague-Dawley normotensive and heterozygous (mRen2)27-transgenic hypertensive rats.

scientific article published on 4 August 2006

Effect of hemorrhagic shock on the concomitant release of endorphin and enkephalin-like peptides from the pituitary and adrenal gland in the dog.

scientific article published in January 1982

Effect of high calcium diet on magnesium, catecholamines, and blood pressure of stroke-prone spontaneously hypertensive rats

scientific article

Effect of intraventricular perfusion of angiotensin II in conscious normal rats and in rats with hereditary hypothalamic diabetes insipidus

scientific article published on December 1, 1976

Effect of losartan on right ventricular hypertrophy and cardiac angiotensin I-converting enzyme activity in pulmonary hypertensive rats

scientific article published on January 1996

Effect of sodium chloride and sodium bicarbonate on blood pressure in stroke-prone spontaneously hypertensive rats

scientific article

Effect of urapidil, clonidine, and prazosin on sympathetic tone in conscious rats

scientific article published on April 1986

Effects of AT1 receptor blockade on blood pressure and the renin-angiotensin system in spontaneously hypertensive rats of the stroke prone strain

scientific article published on February 1998

Effects of Enkephalins on Arterial Blood Pressure are Reduced by Propranolol ⬇️

scientific article published on December 1, 1978

Effects of Human Renin in the Vasculature of Rats Transgenic for Human Angiotensinogen

scientific article published on 01 August 1995

Effects of [D-Ala2]-methionine-enkephalin on blood pressure, heart rate, and baroreceptor reflex sensitivity in conscious cats ⬇️

scientific article published on 01 September 1981

Effects of an Orally Active Converting-Enzyme Inhibitor, SQ 14225, on Pressor Responses to Angiotensin Administered into the Brain Ventricles of Spontaneously Hypertensive Rats ⬇️

scientific article published on January 1, 1979

Effects of angiotensin II and angiotensin II antagonist saralasin on cell growth and renin in 3T3 and SV3T3 cells ⬇️

scientific article published on March 1, 1979

Effects of angiotensin II and of an angiotensin II receptor antagonist on simian virus 40-induced tumor growth in vivo

scientific article published in April 1980

Effects of angiotensin-converting enzyme inhibitors on tissue renin-angiotensin systems

scientific article

Effects of atrial natriuretic factor in rats with renal insufficiency

scientific article published on 01 July 1987

Effects of central and peripheral angiotensin blockade in hypertensive rats ⬇️

scientific article published on May 1, 1978

Effects of chronic sino-aortic denervation in male rats on regional catecholamine levels and turnover and on neuroendocrine function

scientific article published on 01 January 1983

Effects of converting enzyme inhibitors: ramipril and enalapril on peptide action and sympathetic neurotransmission in the isolated heart

scientific article published in July 1985

Effects of hydrochlorothiazide on water, cation, and norepinephrine contents of cardiovascular tissues of renovascular hypertensive dogs

scientific article published on 01 December 1974

Effects of lesions in the paraventricular nucleus of the hypothalamus on vasopressin and oxytocin contents in brainstem and spinal cord of rat

scientific article published on 01 February 1983

Effects of nephrectomy and adrenalectomy on the renin-angiotensin system of transgenic rats TGR(mRen2)27

scientific article published on 01 January 1994

Effects of sodium restriction and cyclooxygenase-2 inhibition on the course of hypertension, proteinuria and cardiac hypertrophy in Ren-2 transgenic rats

scientific article

Effects of sympathetic nerve stimulation are attenuated by the converting enzyme inhibitor Hoe 498 in isolated rabbit hearts

scientific article published on 01 January 1984

Efficiency of transgenic rat production is independent of transgene-construct and overnight embryo culture

article

Emergence and evolution of the renin-angiotensin-aldosterone system ⬇️

scientific article (publication date: May 2012)

Emotional stress and arterial hypertension.

scientific article published on October 1982

Enalapril and renal function in hypertensive rats transgenic for mouse renin gene.

scientific article

Endogenous brain angiotensin II disrupts passive avoidance behavior in rats ⬇️

scientific article published on September 1, 1979

Endogenous tissue renin-angiotensin systems. From molecular biology to therapy

scientific article published on March 1988

Endothelial dysfunction and xanthine oxidoreductase activity in rats with human renin and angiotensinogen genes

scientific article

Endothelial injury in transgenic (mRen-2)27 hypertensive rats

scientific article published on 01 January 1997

Enhanced adrenal renin and aldosterone biosynthesis during sodium restriction in TGR (mREN2)27

scientific article published on 01 October 1994

Enhanced blood pressure buffering role of the brain nitrergic system in renin transgenic rats

scientific article published in September 1999

Enkephalin effects on blood pressure, heart rate, and baroreceptor reflex

scientific article published on 01 July 1980

Entsalzen oder Pökeln?

Estrogen augments the contribution of nitric oxide to blood pressure regulation in transgenic hypertensive rats expressing the mouse Ren-2 gene

scientific article published on 01 July 1994

Estrogen protects transgenic hypertensive rats by shifting the vasoconstrictor-vasodilator balance of RAS

scientific article published on 01 December 1997

Estrogen, nitric oxide, and hypertension differentially modulate agonist-induced contractile responses in female transgenic (mRen2)27 hypertensive rats

scientific article

Evidence against co-storage of enkephalins with noradrenaline in bovine adrenal medullary granules

scientific article published on 01 December 1982

Evidence for a differential modulation of the alpha-2 adrenoceptors by angiotensin II in the nucleus tractus solitarii of the spontaneously hypertensive and the Wistar-Kyoto normotensive rats

scientific article published on 01 May 1995

Evidence for a selective reduction of adrenaline turnover in the dorsal midline area of the caudal medulla oblongata of young spontaneous hypertensive rats ⬇️

scientific article published on 01 December 1979

Evidence for an endogenous brain renin-angiotensin system

scientific article published on August 1, 1979

Evidence for differential localization of angiotensin-l converting enzyme and renin in the corpus striatum of rat ⬇️

scientific article published on 01 November 1980

Evidence for local angiotensin formation in brain of nephrectomized rats

scientific article published in December 1976

Evidence for primary genetic determination of heart rate regulation: chromosomal mapping of a genetic locus in the rat

scientific article published on 01 August 1997

Evidence for the existence of angiotensin II like immunoreactivity in subpopulations of tyrosine hydroxylase immunoreactive neurons in the A1 and C1 area of the ventral medulla of the male rat.

scientific article published in July 1990

Evidence for the existence of angiotensinogen mRNA in magnocellular paraventricular hypothalamic neurons

scientific article published in April 1988

Evidence for the presence of enkephalins in the heart

scientific article

Evidence of renin release or production in splanchnic territory

scientific article

Evolutionary molecular medicine

scientific article published on 29 April 2012

Expression of cytochrome P45011B1 mRNA in the brain of normal and hypertensive transgenic rats

scientific article published in September 1996

Expression of the mouse and rat mas proto-oncogene in the brain and peripheral tissues

scientific journal article

Expression of the mouse ren-2 gene in the small intestine is regulated by food intake

article

Extra-hepatic transcription of plasma prekallikrein gene in human and rat tissues

scientific article

Fast and widespread increase of basic fibroblast growth factor messenger RNA and protein in the forebrain after kainate-induced seizures

scientific article published on 01 December 1993

Fostering trust-- Mol Med's scientific integrity policy

scientific article published on 01 January 2009

Friedrich Cameron Luft turns 60: bridging the New and the Old World

scientific article published on 26 March 2002

From genomics to public health

scientific article

Fulminant hypertension in transgenic rats harbouring the mouse Ren-2 gene

scientific article published in Nature

Gabaergic stimulation inhibits central actions of angiotensin II: pressor responses, drinking and release of vasopressin

scientific article published on 01 May 1983

Gap junction protein connexin40 is preferentially expressed in vascular endothelium and conductive bundles of rat myocardium and is increased under hypertensive conditions

scientific article published on 01 December 1993

Gene expression of brain nitric oxide synthase and soluble guanylyl cyclase in hypothalamus and medulla of two-kidney, one clip hypertensive rats

scientific article published on July 1995

Gene regulation of beta-1-adrenergic receptor in genetically hypertensive rats

scientific article published on 01 December 1993

Genetic basis of hypertension. The renin-angiotensin paradigm

scientific article

Genetic linkage of the ACE gene to plasma angiotensin-converting enzyme activity but not to blood pressure. A quantitative trait locus confers identical complex phenotypes in human and rat hypertension

scientific journal article

Genetic mapping of a gene causing hypertension in the stroke-prone spontaneously hypertensive rat ⬇️

scientific article published on October 4, 1991

Genetic variation in hypertensive and 'control' strains. What are we controlling for anyway?

scientific article published on 01 May 1992

Genetics in arterial hypertension--clinical and experimental aspects.

scientific article published on October 1995

Genetics of primary hypertension

scientific article published on 01 January 1994

Genome sequence of the Brown Norway rat yields insights into mammalian evolution

scientific article

Genome-wide linkage reveals a locus for human essential (primary) hypertension on chromosome 12p

scientific article published on 01 June 2003

Glial angiotensinogen regulates brain angiotensin II receptors in transgenic rats TGR(ASrAOGEN).

scientific article

Gluco- and mineralocorticoid receptor-mediated regulation of neurotrophic factor gene expression in the dorsal hippocampus and the neocortex of the rat.

scientific article published in August 2000

Glucocorticoid- and estrogen-responsive elements in the 5'-flanking region of the rat angiotensinogen gene

scientific article published on November 1991

Gonadectomy and hormonal replacement changes systolic blood pressure and ventricular myosin isoenzyme pattern of spontaneously hypertensive rats

scientific article

Growth, metabolism, and blood pressure disturbances during aging in transgenic rats with altered brain renin-angiotensin systems

scientific article published on 30 August 2005

Health co-benefits of policies to tackle climate change ⬇️

scientific article published on November 27, 2010

Hearing loss: a global health issue

scientific article published on 3 March 2015

High blood pressure in transgenic mice carrying the rat angiotensinogen gene ⬇️

scientific article published on March 1, 1992

High blood pressure maintenance in transgenic mRen-2 vs. Lyon genetically hypertensive rats

scientific article published on 01 July 1993

High human renin hypertension in transgenic rats.

scientific article

High levels of human chymase expression in the pineal and pituitary glands

scientific article published in March 1997

High-throughput scanning of the rat genome using interspersed repetitive sequence-PCR markers

scientific article

How to deal with scientific controversy?

scientific article published on 01 December 2002

Human angiotensinogen is highly expressed in astrocytes in human cortical grafts

scientific article

Human renin-dependent hypertension in rats transgenic for human angiotensinogen

scientific article

Humoral and neurohormonal aspects of blood pressure regulation: Focus on angiotensin ⬇️

scientific article published on January 1, 1978

Hypertension transmitted by kidneys from stroke-prone spontaneously hypertensive rats

scientific article published on 01 August 1989

Hypothalamic substance P release. Attenuated angiotensin responses in mRen2(27) transgenic rats

scientific article published in January 1997

Identification of hypertension-related genes through an integrated genomic-transcriptomic approach

scientific article published on 24 February 2005

Immobilization stress induces vasodepressor and altered neuroendocrine responses in the adult stroke-prone spontaneously hypertensive male rat

scientific article published on 01 December 1993

Immunohistochemical evidence for the existence of angiotensin II-containing nerve terminals in the brain and spinal cord in the rat.

scientific article published in June 1976

Immunohistochemistry of the Renin-Angiotensin-System in the kidney ⬇️

scientific article published on January 1, 1983

Impaired vasorelaxant responses to natriuretic peptides in the stroke-prone phenotype of spontaneously hypertensive rats

scientific article published in February 1998

Impermeability of the blood-cerebrospinal fluid barrier for angiotensin II in rats

scientific article published on December 1, 1976

Implementing the Proclamation of Stroke and Potentially Preventable Dementias

scientific article published on 01 October 2018

Implementing the proclamation of stroke and potentially preventable dementias

scientific article published on 09 October 2018

Importance of extrarenal renin systems in the pathogenesis of arterial hypertension

scientific article published on 01 January 1991

Improved immunohistochemical staining of angiotensin II in rat brain using affinity purified antibodies

scientific article

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Lipoic acid supplementation prevents angiotensin II-induced renal injury

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Plasma atrial natriuretic peptide values in cardiac disease

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Renin increases blood-pressure ⬇️

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SA446, a new orally active converting enzyme inhibitor: Antihypertensive action and comparison with captopril in stroke-prone spontaneously hypertensive rats ⬇️

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The central pressor actions of substance P are inhibited by GABA

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The iso-renin angiotensin systems in extrarenal tissue

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The localization of converting enzyme in kidney vessels of the rat ⬇️

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The renin and iso-renin-angiotensin system in rats with experimental pitutary tumors (38585) ⬇️

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Unlike human hypertension, blood pressure in a hereditary hypertensive rat strain shows no linkage to the angiotensinogen locus

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Worse than pulp fiction: fraud in science.

scientific article published in October 1997

Zona glomerulosa of the adrenal gland in a transgenic strain of rat: a morphologic and functional study

scientific article

Zonal distribution and regulation of adrenal renin in a transgenic model of hypertension in the rat

scientific article published on 01 October 1992

[A simple sensitive micromethod for measurement of human plasma renin concentration].

scientific article published in September 1972

[Development of a model of human renin hypertension in rats]

scientific article published on 01 August 1996

[Diagnosis and therapy of mild hypertension]

scientific article published on 01 November 1983

[Dopamine in the kidney: a further natriuretic hormone?]

scientific article published on 01 April 1985

[Genes and hypertension. Genetic analysis instead of fasting?]

scientific article published in April 1990

[Primary hyperreninemia. An unusual cause of secondary arterial hypertension]

scientific article published on 01 August 1993

[Renin-Angiotensin-System (RAS) and COVID-19 - On The Prescription of RAS Blockers]

scientific article published on 22 April 2020

[Some new aspects of the renin-angiotensin system]

scientific article published on 01 April 1973

List of works by Detlev Ganten

151 years Berliner Klinische Wochenschrift and the 20th anniversary of the Journal of Molecular Medicine

2-[N-[(S)-1-ethoxycarbonyl-3-phenylpropyl]-L-alanyl]-(1S,3S,5S)-2- azabicyclo[3.3.0]octane-3-carboxylic acid (Hoe 498): antihypertensive action and persistent inhibition of tissue converting enzyme activity in spontaneously hypertensive rats

A Novel Orally Active Converting-Enzyme Inhibitor Ys 980: Effects on Blood Pressure in Spontaneously Hypertensive Rats ⬇️

A SNP map of the rat genome generated from cDNA sequences

A micromethod for the measurement of renin in brain nuclei: Its application in spontaneously hypertensive rats ⬇️

A transgenic rat expressing human APP with the Swedish Alzheimer's disease mutation

Academic medicine must take its global role: the M8 Alliance of Academic Health Centers and Medical Universities ⬇️

Actions of angiotensin and lisinopril on thalamic somatosensory neurons in normotensive, non-transgenic and hypertensive, transgenic rats

Activation of the renin-angiotensin system in heart failure and hypertrophy--studies in human hearts and transgenic rats

Acute effects of cyclooxygenase-2 inhibition on renal function in heterozygous ren-2-transgenic rats on normal or low sodium intake

Acute sino-aortic denervation in rats produces a selective increase of adrenaline turnover in the dorsal midline area of the caudal medulla oblongata and a reduction of adrenaline levels in the anterior and posterior hypothalamus

Adrenal renin is released into the circulation of the hypertensive transgenic rat TGR (mRen-2)27

Alpha atrial natriuretic peptide concentrations in plasma of children with congenital heart and pulmonary diseases.

Alterations in blood pressure and heart rate variability in transgenic rats with low brain angiotensinogen

Alterations in sympathetic ganglionic transmission in response to angiotensin II in (mRen2)27 transgenic rats

Alterations of cardiac alpha- and beta-adrenoceptors and inotropic responsiveness in hypertensive transgenic rats harbouring the mouse renin gene (TGR(mREN2)27)

Alterations of the renin-angiotensin system at the RVLM of transgenic rats with low brain angiotensinogen

Altered angiotensinogen amino acid sequence and plasma angiotensin II levels in genetically hypertensive rats. A study on cause and effect

Altered neuropeptide concentrations in spontaneously hypertensive rats: cause or consequence?

Alternative splicing of the mRNA coding for the human endothelial angiotensin-converting enzyme: a new mechanism for solubilization

Aminergic and peptidergic pathways in the nervous system with special reference to the hypothalamus

An old couple: the renin–angiotensin system (RAS) and the Journal of Molecular Medicine (JMolMed)

Androgen dependence and tissue specificity of renin messenger RNA expression in mice

Angiotensin I converting enzyme and chymase in cardiovascular tissues.

Angiotensin II (AT(1)) receptor blockade reduces vascular tissue factor in angiotensin II-induced cardiac vasculopathy

Angiotensin II AT1-receptor blockade inhibits monocyte activation and adherence in transgenic (mRen2)27 rats

Angiotensin II controls angiotensinogen secretion at a pretranslational level

Angiotensin II immunoreactive pathways in the central nervous system of the rat: evidence for a projection from the subfornical organ to the paraventricular nucleus of the hypothalamus

Angiotensin II immunoreactivity in the neural afferents and efferents of the subfornical organ of the rat.

Angiotensin II induced inflammation in the kidney and in the heart of double transgenic rats

Angiotensin II induces connective tissue growth factor gene expression via calcineurin-dependent pathways

Angiotensin II receptor blockade in TGR(mREN2)27: effects of renin-angiotensin-system gene expression and cardiovascular functions

Angiotensin and cell growth: a link to cardiovascular hypertrophy?

Angiotensin biosynthesis and concentrations in brain of normotensive and hypertensive rats

Angiotensin formation in the isolated rat hindlimb

Angiotensin peptides acting at rostral ventrolateral medulla contribute to hypertension of TGR(mREN2)27 rats

Angiotensin stimulates oxytocin release ⬇️

Angiotensin stimulates oxytocin release: impaired response in rats with genetic hypothalamic diabetes insipidus

Angiotensin stimulates oxytocin release: imparied response in rats with genetic hypothalamic diabetes insipidus

Angiotensin stimulates β-endorphin release from anterior pituitary gland cell cultures of rats ⬇️

Angiotensin synthesis in the brain and increased turnover in hypertensive rats

Angiotensin-(1-7) and baroreflex function in nucleus tractus solitarii of (mRen2)27 transgenic rats

Angiotensin-converting enzyme inhibition and AT1 receptor blockade modify the pressure-natriuresis relationship by additive mechanisms in rats with human renin and angiotensinogen genes.

Angiotensin-converting enzyme-independent pathways of angiotensin II formation in human tissues and cardiovascular diseases

Angiotensin-forming enzyme in brain tissue

Angiotensin-induced hypertension in the rat. Sympathetic nerve activity and prostaglandins

Angiotensin-like activity in resistance vessels. Immunocytochemical study in Chinese hamsters.

Angiotensinogen concentrations and renin clearance : implications for blood pressure regulation

Angiotensinogen gene expression in extrahepatic rat tissues: application of a solution hybridization assay

Angiotensinogen is cleaved to angiotensin in isolated rat blood vessels

Angiotensinogen mRNA and pressor reactions to angiotensin in brain stem areas of spontaneously hypertensive rats

Angiotensinogen messenger RNA stabilization by angiotensin II.

Antihypertensive Effects of the Novel Converting-Enzyme Inhibitor YS 980 in Spontaneously Hypertensive Rats ⬇️

Antihypertensive action and inhibition of tissue conversion enzyme by ramipril, perindopril and enalapril in the spontaneously hypertensive rat (SHRSP)

Antihypertensive action and inhibition of tissue converting enzyme (CE) by three prodrug CE inhibitors, enalapril, ramipril and perindopril in stroke-prone spontaneously hypertensive rats

Antihypertensive action of the converting enzyme inhibitor perindopril (S9490-3) in spontaneously hypertensive rats: comparison with enalapril (MK421) and ramipril (Hoe498).

Antihypertensive effect of the GABA receptor agonist muscimol in spontaneously hypertensive rats. Role of the sympathoadrenal axis

Antisense oligonucleotide to c-fos induces ipsilateral rotational behaviour to d-amphetamine.

Aspects of molecular biology and biochemistry of the cardiac renin-angiotensin system

Aspirin inhibits NF-kappaB and protects from angiotensin II-induced organ damage

Assignment of the kinin receptor B1 and B2 genes (Bdkrb1 and Bdkrb2) to rat chromosome 6q3.2 by FISH and radiation hybrid mapping

Association and cosegregation of stroke with impaired endothelium-dependent vasorelaxation in stroke prone, spontaneously hypertensive rats.

Atrial natriuretic factor determinations and chronic sodium homeostasis

Atrial natriuretic factor in sodium-sensitive and sodium-resistant Dahl rats

Atrial natriuretic factor—a circulating hormone stimulated by volume loading

Atrial natriuretic peptide and volume changes in children

Atrial natriuretic peptide: a new factor in blood pressure control

Atrial natriuretic peptides in brain nuclei of rats with inherited diabetes insipidus (Brattleboro rats).

Atriopeptin III kinetics and pharmacodynamics in normal and anephric rats

Augmented agonist-induced Ca(2+)-sensitization of coronary artery contraction in genetically hypertensive rats. Evidence for altered signal transduction in the coronary smooth muscle cells

Autoradiographic localization of mas proto-oncogene mRNA in adult rat brain using in situ hybridization

Baroreceptor reflex regulation in anesthetized transgenic rats with low glia-derived angiotensinogen

Basic fibroblast growth factor expression and tenascin C immunoreactivity after partial unilateral hemitransection of the rat brain

Basic methodology in the molecular characterization of genes

Beta-adrenergic neuroeffector mechanisms in cardiac hypertrophy of renin transgenic rats

Blockade of endothelin receptors attenuates end-organ damage in homozygous hypertensive ren-2 transgenic rats

Blood Pressure Effects of Endogenous Brain Angiotensin in Rats are Increased by Inhibition of Prostaglandin Biosynthesis ⬇️

Blood Pressure and Heart Rate Responses to Centrally Administered Substance P Are Increased in Spontaneously Hypertensive Rats ⬇️

Blood pressure reduction and diabetes insipidus in transgenic rats deficient in brain angiotensinogen