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List of works by Tsutomu Chiba

A Marker for Dormant Cancer Stem Cells in Human Hepatocellular Carcinoma ⬇️

scientific article published on February 24, 2011

A case of autoimmune pancreatitis associated with sclerosing cholangitis, retroperitoneal fibrosis and Sjögren's syndrome

scientific article published on 16 March 2005

A case of erythropoietic protoporphyria with severe liver dysfunction

scientific article published in May 2011

A case of esophageal ulcer caused by alendronate sodium tablets ⬇️

scientific article published on 01 May 2011

A case of ileal heterotopic pancreas with repeated melena

scientific article published on 20 September 2006

A case of long-term survival of metastatic desmoplastic small round cell tumor treated with multimodal therapy

scientific article

A cleaved form of MAGE-A4 binds to Miz-1 and induces apoptosis in human cells

scientific article

A coordinated cytotoxic effect of IFN-gamma and cross-reactive antibodies in the pathogenesis of Helicobacter pylori gastritis

scientific article published on August 2003

A liver abscess deprived a healthy adult of eyesight: endogenous endophthalmitis associated with a pyogenic liver abscess caused by serotype K1 Klebsiella pneumonia

scientific article published on 15 April 2013

A liver tolerates a portal antigen by generating CD11c+ cells, which select Fas ligand+ Th2 cells via apoptosis

scientific article published on 01 August 2003

A model of liver carcinogenesis originating from hepatic progenitor cells with accumulation of genetic alterations ⬇️

scientific article published on September 16, 2013

A multi-institution phase II study of gemcitabine/S-1 combination chemotherapy for patients with advanced biliary tract cancer ⬇️

scientific article published on September 2, 2010

A novel mechanism for H. pylori-induced cell damage--induction of gene mutation by AID

scientific article published in December 2009

A novel mechanism for inflammation-associated carcinogenesis; an important role of activation-induced cytidine deaminase (AID) in mutation induction

scientific article published on October 2009

A phase I study investigating the safety and pharmacokinetics of highly bioavailable curcumin (Theracurmin®) in cancer patients ⬇️

scientific article published on March 30, 2013

A phase I/II study of gemcitabine-based chemotherapy plus curcumin for patients with gemcitabine-resistant pancreatic cancer ⬇️

scientific article published on September 22, 2010

A retrospective analysis on the utility and complications of upper arm ports in 433 cases at a single institute

scientific article published on 27 October 2015

A role of Helicobacter pylori infection in the development of duodenal ulcer after adult living-related liver transplantation

scientific article

A tumor stem cell-specific marker identified by lineage tracing in the intestine

scientific article

ARID1A Maintains Differentiation of Pancreatic Ductal Cells and Inhibits Development of Pancreatic Ductal Adenocarcinoma in Mice

scientific article published on 28 March 2018

Aberrant expansion of segmented filamentous bacteria in IgA-deficient gut

scientific journal article

Aberrant expression of EZH2 is associated with a poor outcome and P53 alteration in squamous cell carcinoma of the esophagus.

scientific article

Accumulation of somatic mutations in TP53 in gastric epithelium with Helicobacter pylori infection ⬇️

scientific article published on 29 April 2014

Acquisition of Genetic Aberrations by Activation-Induced Cytidine Deaminase (AID) during Inflammation-Associated Carcinogenesis

scientific article published on 22 June 2011

Activation and differentiation of autoreactive B-1 cells by interleukin 10 induce autoimmune hemolytic anemia in Fas-deficient antierythrocyte immunoglobulin transgenic mice

scientific article

Activation of TNF-α-AID axis and co-inhibitory signals in coordination with Th1-type immunity in a mouse model recapitulating hepatitis B.

scientific article published on 4 January 2017

Activation of type I IFN signaling by NOD1 mediates mucosal host defense against Helicobacter pylori infection

scientific article published on January 2011

Activation-Induced Cytidine Deaminase Contributes to Pancreatic Tumorigenesis by Inducing Tumor-Related Gene Mutations.

scientific article published on 25 June 2015

Activation-induced cytidine deaminase links between inflammation and the development of colitis-associated colorectal cancers

scientific article published on 18 July 2008

Activation-induced cytidine deaminase links bile duct inflammation to human cholangiocarcinoma

scientific article

Acute Epstein-Barr virus infection presenting as severe gastroenteritis without infectious mononucleosis-like manifestations

scientific article

Acute airway obstruction in a patient with achalasia

scientific article

Acute cerebral infarction during combination chemotherapy with s-1 and cisplatin for a young patient with a mucin-producing adenocarcinoma of the stomach

scientific article published on 16 October 2006

Acute graft-versus-host disease in the small intestine

scientific article published on 01 May 2002

Adenomyoma of the minor duodenal papilla

scientific article published on 01 March 2005

Administration of an antigen at a high dose generates regulatory CD4+ T cells expressing CD95 ligand and secreting IL-4 in the liver

scientific article published on 01 March 2002

Adminstration of PEG-Interferon to a Patient with Ulcerative Colitis and Chronic Hepatitis C Correlated with Reduced Colonic Inflammation and Reversal of Peripheral Th1/Th2 Ratios ⬇️

scientific article published on December 21, 2007

Age and immunoglobulin G4-associated autoimmune hepatitis: author's response

Alteration of CXCR4 expression and Th1/Th2 balance of peripheral CD4-positive T cells can be a biomarker for leukocytapheresis therapy for patients with refractory ulcerative colitis

scientific article published on 01 July 2009

Analysis of K-ras mutations and expression of cyclooxygenase-2 and gastrin protein in laterally spreading tumors.

scientific article

Analysis of humoral immune response in experimental autoimmune pancreatitis in mice.

scientific article published in March 2010

Anti-viral protein APOBEC3G is induced by interferon-alpha stimulation in human hepatocytes.

scientific article published on 10 January 2006

Antibody to hepatitis B core antigen and risk for hepatitis C-related hepatocellular carcinoma: a prospective study

scientific article published on 01 May 2007

Antibody to hepatitis B core antigen as a screening test for occult hepatitis B virus infection in Egyptian chronic hepatitis C patients

scientific article

Are immunoglobulin G4-positive multiorgan lymphoproliferative syndrome and autoimmune pancreatitis different manifestations of a common clinicopathologic entity?

scientific article published on 21 December 2009

Are prophylactic antibiotics really ineffective in reducing the risk of pancreatic necrosis?

scientific article published on 01 August 2008

Arid1a is essential for intestinal stem cells through Sox9 regulation

scientific article published on 11 January 2019

Asia-Pacific consensus guidelines on gastric cancer prevention

scientific article published on March 2008

Associations between glutathione S-transferase pi Ile105Val and glyoxylate aminotransferase Pro11Leu and Ile340Met polymorphisms and early-onset oxaliplatin-induced neuropathy.

scientific article published on 21 March 2010

Attenuation of proteolysis-mediated cyclin E regulation by alternatively spliced Parkin in human colorectal cancers

scientific article

Autoimmune pancreatitis exhibiting multiple mass lesions

scientific article published on 10 September 2011

Benign gastric carcinoid tumor with hypergastrinemia followed up for 12 years

scientific article published on 01 December 2000

Bifid tail of the pancreas with localized acute pancreatitis.

scientific article published on 29 October 2013

Bile acid-induced expression of activation-induced cytidine deaminase during the development of Barrett’s oesophageal adenocarcinoma ⬇️

scientific article published on September 1, 2011

Biliary complications after a right-lobe living donor liver transplantation

scientific article

Biliary complications in donors for living donor liver transplantation

scientific article published on 28 May 2008

Bioactive insulin-like growth factors as a possible molecular target for non-islet cell tumor hypoglycemia.

scientific article published on January 2014

Biodegradable microspheres targeting mucosal immune-regulating cells: new approach for treatment of inflammatory bowel disease

scientific article published on March 1, 2003

Blockade of CXCL12/CXCR4 Axis Ameliorates Murine Experimental Colitis

scientific article published on 20 August 2008

Blockade of paracrine supply of insulin-like growth factors using neutralizing antibodies suppresses the liver metastasis of human colorectal cancers

scientific article

Bmi1 marks gastric stem cells located in the isthmus in mice

scientific article published on 20 February 2019

Brg1 plays an essential role in development and homeostasis of the duodenum through regulation of Notch signaling

scientific article

CD4+CD25+ T cells regulate colonic localization of CD4 T cells reactive to a microbial antigen.

scientific article

COX-2 inhibition alters the phenotype of tumor-associated macrophages from M2 to M1 in ApcMin/+ mouse polyps

scientific article published on 05 July 2011

CXCR4 in tumor epithelial cells mediates desmoplastic reaction in pancreatic ductal adenocarcinoma

scientific article published on 30 June 2020

Caecal cancer associated with longstanding Crohn's disease

scientific article published on 01 November 2006

Candidate markers for stem and early progenitor cells, Musashi-1 and Hes1, are expressed in crypt base columnar cells of mouse small intestine

scientific article

Card15 Polymorphisms in the Immunopathogenesis of Crohn's Disease and Mycobacterial Infectious Diseases ⬇️

scientific article published on October 20, 2010

Case of IgG4-associated sclerosing cholangitis with normal serum IgG4 concentration, diagnosed by anti-laminin 511-E8 antibody: a novel autoantibody in patients with autoimmune pancreatitis

scientific article published on 13 February 2019

Case of chronic pancreatitis involving an autoimmune mechanism that extended to retroperitoneal fibrosis.

scientific article published in January 2003

Case-control study on the association of upper gastrointestinal bleeding and nonsteroidal anti-inflammatory drugs in Japan

scientific article (publication date: September 2006)

Catheter US probe EUS evaluation of gastric cardia and perigastric vascular structures to predict esophageal variceal recurrence

scientific article published in February 2002

Cecal ameboma

scientific article published on 01 September 2005

Cecal necrosis due to ischemic colitis mimicking an abscess on sonography

scientific article published in March 2006

Cerebral air embolism caused by chemoradiotherapy for esophageal cancer

scientific article published on 23 July 2012

Characteristics of Japanese patients with chronic gastritis and comparison with functional dyspepsia defined by ROME III criteria: based on the large-scale survey, FUTURE study

scientific article

Characteristics of gastric B-cell lymphoma of mucosa-associated lymphoid tissue type involving multiple organs.

scientific article

Characteristics of hepatocellular carcinoma with stem/progenitor cell phenotypes.

scientific article

Characterization of mesendoderm: a diverging point of the definitive endoderm and mesoderm in embryonic stem cell differentiation culture

scientific article published on September 2005

Chemokine CXCL16 mediates acinar cell necrosis in cerulein induced acute pancreatitis in mice.

scientific article

Chronic inflammation and gastric cancer development

scientific article published on 01 October 2012

Chronic rejection associated with antiviral therapy for recurrent hepatitis C after living-donor liver transplantation.

scientific article published on February 2014

Circulating antibody to hepatitis B core antigen does NOT always reflect the latent hepatitis B virus infection in the liver tissue

scientific article published in February 2003

Cirp protects against tumor necrosis factor-alpha-induced apoptosis via activation of extracellular signal-regulated kinase

scientific article published on 20 March 2006

Clinical Challenges and Images in GI. Unique gastrointestinal involvement in a patient with Henoch-Schonlein purpura

scientific article published on 01 October 2007

Clinical Characteristics of Non-B Non-C Hepatocellular Carcinoma: A Single-Center Retrospective Study

Clinical Features, Response to Treatment, and Outcomes of IgG4-Related Sclerosing Cholangitis

scientific article published on 19 January 2017

Clinical challenges and images in GI. Image 4. Transplant-associated thrombotic microangiopathy of the colon accompanied by graft-versus-host disease

scientific article

Clinical challenges and images in GI. Meckel's diverticulum with an enterolith.

scientific article published in August 2006

Clinical characteristics of Japanese patients with eosinophilic esophagitis and eosinophilic gastroenteritis ⬇️

scientific article published on July 31, 2012

Clinical course of type 1 autoimmune pancreatitis patients without steroid treatment: a Japanese multicenter study of 97 patients

scientific article published on 12 February 2018

Clinical features of Japanese patients with colonic angiodysplasia

scientific article published on 27 August 2007

Clinical outcome of gemcitabine/S-1 combination therapy for advanced pancreatic cancer

scientific article

Clinical practice guidelines for IgG4-related sclerosing cholangitis

scientific article published on 18 January 2019

Clinical significance of serum diamine oxidase activity in inflammatory bowel disease: Importance of evaluation of small intestinal permeability

scientific article published on 16 December 2010

Clinical significance of serum thioredoxin 1 levels in patients with acute pancreatitis

scientific article published on 01 April 2006

Colonic polyposis associated with autoimmune pancreatitis

scientific article published on 01 October 2009

Colonoscopic classification of internal hemorrhoids: usefulness in endoscopic band ligation

scientific article published in January 2005

Colonoscopic removal of a denture migrated in the appendix

scientific article published in November 2017

Colorectal advanced neoplasms occur through dual carcinogenesis pathways in individuals with coexisting serrated polyps

scientific article

Combination of ADH1B*2/ALDH2*2 polymorphisms alters acetaldehyde‐derived DNA damage in the blood of Japanese alcoholics ⬇️

scientific article published on July 24, 2012

Combination of Endoscopic Resection and Heat Ablation Is a Promising Endoscopic Therapy for Adenoma-Like Dysplastic Lesion in Chronic Ulcerative Colitis

scientific article published on 29 April 2009

Comparative outcomes between initially unresectable and recurrent cases of advanced pancreatic cancer following palliative chemotherapy

scientific article published on 01 April 2014

Composite regulation of ERK activity dynamics underlying tumour-specific traits in the intestine.

scientific article

Comprehensive diagnostic criteria for IgG4-related disease (IgG4-RD), 2011

scientific article published on 05 January 2012

Concomitant Case of Intraductal Papillary Mucinous Neoplasm of the Pancreas and Functioning Pancreatic Neuroendocrine Tumor (Vasoactive Intestinal Polypeptide-Producing Tumor): First Report

scientific article published in July 2016

Conversion from latent to symptomatic Sheehan's syndrome by pegylated interferon therapy for chronic hepatitis C.

scientific article published on 15 May 2008

Correction: Pretransplant Serum Hepatitis C Virus RNA Levels Predict Response to Antiviral Treatment after Living Donor Liver Transplantation.

scientific article published on 13 November 2013

Crane-neck deformity after right lobe living donor liver transplantation

scientific article published on 19 May 2006

Cross-primed CD8+ cytotoxic T cells induce severe Helicobacter-associated gastritis in the absence of CD4+ T cells

scientific article published on 01 October 2007

Current approach to the diagnosis of IgG4-related disease - Combination of comprehensive diagnostic and organ-specific criteria

scientific article published on 6 February 2017

Cyclooxygenase 2- and prostaglandin E(2) receptor EP(2)-dependent angiogenesis in Apc(Delta716) mouse intestinal polyps

scientific journal article

Cyclooxygenase-2 expression and angiogenesis in gastric hyperplastic polyp--association with polyp size

scientific article published on 01 January 2003

Cytomegalovirus infection in patients with ulcerative colitis diagnosed by quantitative real-time PCR analysis.

scientific article

DMBT1 is a novel gene induced by IL-22 in ulcerative colitis ⬇️

scientific article published on September 7, 2010

Dclk1 distinguishes between tumor and normal stem cells in the intestine

scientific article published on 2 December 2012

De novo activation of HBV with escape mutations from hepatitis B surface antibody after living donor liver transplantation

scientific article

De novo hepatitis B virus infection in hepatocellular carcinoma following eradication of hepatitis C virus by interferon therapy.

scientific article published in June 2010

Decrease in alpha-fetoprotein levels predicts reduced incidence of hepatocellular carcinoma in patients with hepatitis C virus infection receiving interferon therapy: a single center study.

scientific article published on 23 November 2011

Defective interleukin-10 signaling in human inflammatory bowel disease

scientific article published on 19 March 2010

Deletion of nardilysin prevents the development of steatohepatitis and liver fibrotic changes

scientific article

Diagnosis and treatment of obscure GI bleeding at double balloon endoscopy

scientific article published in September 2007

Diagnosis and treatment of obscure GI bleeding with double balloon endoscopy

scientific article published in September 2007

Diagnosis and treatment of small-bowel stricture by double balloon endoscopy

scientific article published in September 2007

Diagnostic performance of a new endoscopic scraper for malignant biliary strictures: a multicenter prospective study

scientific article

Differences of image enhancement in image-enhanced endoscopy: narrow band imaging versus flexible spectral imaging color enhancement

scientific article published on 26 May 2011

Differential localization of colitogenic Th1 and Th2 cells monospecific to a microflora-associated antigen in mice.

scientific article

Differentiation-inducing factor-1 (DIF-1) inhibits STAT3 activity involved in gastric cancer cell proliferation via MEK-ERK-dependent pathway

scientific article

Diffuse colon cancer with tumor thrombus in the portal vein

scientific article published on 01 February 2002

Diffuse hepatoid adenocarcinoma in the peritoneal cavity

scientific article published in November 2006

Disease severity is linked to an increase in autoantibody diversity in IgG4-related disease: comment on the article by Liu H et al

scientific article published on 10 June 2020

Distinct Roles of HES1 in Normal Stem Cells and Tumor Stem-like Cells of the Intestine.

scientific article published on 23 May 2017

Distinct effects of EGFR inhibitors on epithelial- and mesenchymal-like esophageal squamous cell carcinoma cells.

scientific article

Diverse p53 gene aberration in hepatocellular carcinoma detected by dual-color fluorescence in situ hybridization

scientific article published on 01 September 2004

Dose-escalation and pharmacokinetic study of nanoparticle curcumin, a potential anticancer agent with improved bioavailability, in healthy human volunteers ⬇️

scientific article published on May 21, 2011

Down-regulation of RUNX1, RUNX3 and CBFbeta in hepatocellular carcinomas in an early stage of hepatocarcinogenesis.

scientific article published on September 2006

Dual roles of CagA protein in Helicobacter pylori-induced chronic gastritis in mice ⬇️

scientific article published on July 28, 2011

Dynamics of defective hepatitis C virus clones in reinfected liver grafts in liver transplant recipients: ultradeep sequencing analysis.

scientific article published on 28 August 2013

Dynamics of hepatitis B virus quasispecies in association with nucleos(t)ide analogue treatment determined by ultra-deep sequencing

scientific article

Dysregulated Generation of Follicular Helper T Cells in the Spleen Triggers Fatal Autoimmune Hepatitis in Mice ⬇️

scientific article published on January 13, 2011

EP4 Receptor-Associated Protein in Macrophages Ameliorates Colitis and Colitis-Associated Tumorigenesis

scientific article published on 6 October 2015

Early Detection of 5-FU-induced Acute Leukoencephalopathy on Diffusion-Weighted MRI ⬇️

scientific article published on October 6, 2010

Early diagnosis of pancreatic necrosis based on perfusion CT to predict the severity of acute pancreatitis.

scientific article published on 3 April 2017

Ectopic pancreas at the jejunum

scientific article published on 31 May 2010

Ectopic pancreas formation in Hes1 -knockout mice reveals plasticity of endodermal progenitors of the gut, bile duct, and pancreas.

scientific article

Effect and Safety of Granulocyte-Monocyte Adsorption Apheresis for Patients with Ulcerative Colitis Positive for Cytomegalovirus in Comparison with Immunosuppressants ⬇️

scientific article published on 09 February 2011

Effect of EP4 agonist (ONO-4819CD) for patients with mild to moderate ulcerative colitis refractory to 5-aminosalicylates: a randomized phase II, placebo-controlled trial.

scientific article published in May 2010

Effect of immunosuppressants on inflammatory bowel disease: tacrolimus and cyclosporine

scientific article published on 01 February 2012

Effect of infliximab on inflammatory bowel disease with Takayasu arteritis: case series and review of the literature

scientific article published on 10 May 2013

Effective treatment for de novo hepatitis B with nucleotide analogue in patients with hematological malignancies

scientific article

Effects of Helicobacter pylori infection on the link between regenerating gene expression and serum gastrin levels in Mongolian gerbils

scientific article published in December 2003

Effects of obstructive sleep apnea syndrome on serum aminotransferase levels in obese patients ⬇️

scientific article published on April 1, 2003

Efficacy and safety of granulocyte and monocyte adsorption apheresis for ulcerative colitis: a meta-analysis

scientific article published on 21 November 2013

Efficacy and safety of infliximab as rescue therapy for ulcerative colitis refractory to tacrolimus

scientific article published in May 2010

Efficacy and safety of omeprazole in Japanese patients with nonerosive reflux disease

scientific article

Efficacy and safety of prophylaxis with entecavir and hepatitis B immunoglobulin in preventing hepatitis B recurrence after living-donor liver transplantation

scientific article published in May 2012

Efficacy of oral tacrolimus on intestinal Behcet's disease.

scientific article

Efficacy of preventive endoscopic balloon dilation for esophageal stricture after endoscopic resection

scientific article published in March 2011

Efficacy of surveillance and molecular markers for detection of ulcerative colitis-associated colorectal neoplasia

scientific article published on January 2003

Elimination of local macrophages in intestine prevents chronic colitis in interleukin-10-deficient mice

scientific article published in February 2003

Endoscopic evaluation of low-dose aspirin-induced gastric and duodenal ulcers during prophylaxis with lansoprazole

scientific article published on March 11, 2013

Endoscopic intraluminal cutting technique for indwelling devices using a lithotripter handle and guidewire

scientific article published on 22 June 2015

Endoscopic management is an accepted first-line therapy for biliary complications after adult living donor liver transplantation

scientific article published in June 2007

Endoscopic management of biliary stricture after right-lobe living-donor liver transplantation with biliary anastomosis

scientific article published on 01 October 2006

Endoscopic management of biliary strictures after duct-to-duct biliary reconstruction in right-lobe living-donor liver transplantation ⬇️

scientific article published on September 15, 2003

Endoscopic management of postoperative biliary complications in donors for living donor liver transplantation

scientific article published in May 2003

Endoscopic retrieval of broken external biliary stents from the bile duct after right-lobe living-donor liver transplantation

scientific article published on 01 April 2003

Endoscopic stent placement above the intact sphincter of Oddi for biliary strictures after living donor liver transplantation ⬇️

scientific article published on January 17, 2013

Endoscopic treatment of biliary complications after right-lobe living-donor liver transplantation with duct-to-duct biliary anastomosis

scientific article published on 30 November 2006

Endoscopic ultrasonograph evaluation of vascular structures in the gastric cardia predicts esophageal variceal recurrence following endoscopic treatment.

scientific article published in January 2006

Endoscopically resected long giant polypoidal lesion caused by arteriovenous malformation

scientific article published on 22 April 2018

Enhanced cytokine responses to Toll-like and NOD-like receptor ligands in primary biliary cirrhosis-CREST overlap syndrome

scientific article published on 12 April 2010

Enhanced expression of activation-induced cytidine deaminase in human gastric mucosa infected by Helicobacter pylori and its decrease following eradication ⬇️

scientific article published on April 18, 2013

Epstein-Barr virus-associated lymphoma developed shortly after immunosuppressive treatment for ulcerative colitis

scientific article

Erratum to: Early diagnosis of pancreatic necrosis based on perfusion CT to predict the severity of acute pancreatitis.

scientific article published on 26 April 2017

Esophageal intramural pseudodiverticulosis

scientific article published on 01 May 2004

Essential role of Peyer's patches in the development of Helicobacter-induced gastritis

scientific article published on 20 February 2007

Establishment of a Quick and Highly Accurate Breath Test for ALDH2 Genotyping

scientific article

Establishment of a novel mouse model of ulcerative colitis with concomitant cytomegalovirus infection: in vivo identification of cytomegalovirus persistent infected cells

scientific article published on August 2013

Excessive activity of apolipoprotein B mRNA editing enzyme catalytic polypeptide 2 (APOBEC2) contributes to liver and lung tumorigenesis.

scientific article

Experimental immune-mediated pancreatitis in neonatally thymectomized mice immunized with carbonic anhydrase II and lactoferrin

scientific article published on 01 April 2002

Exposure-toxicity relationship of sorafenib in Japanese patients with renal cell carcinoma and hepatocellular carcinoma

scientific article

Expression of APOBEC2 is transcriptionally regulated by NF-kappaB in human hepatocytes.

scientific article published on 3 January 2006

Expression of Reg family genes in the gastrointestinal tract of mice treated with indomethacin

scientific article published on 6 March 2015

Expression of activation-induced cytidine deaminase in human hepatocytes during hepatocarcinogenesis.

scientific article published on February 2007

Expression of cytokeratin 7 predicts survival in stage I/IIA/IIB squamous cell carcinoma of the esophagus

scientific article published on 01 November 2008

Expression of reg I alpha protein in human gastric cancers.

scientific article published on 27 May 2004

Expression of the REG IV gene in ulcerative colitis

scientific article

Expression profile of REG family proteins REG Ialpha and REG IV in advanced gastric cancer: comparison with mucin phenotype and prognostic markers

scientific article published on 27 March 2009

Factors contributing to the development of gastric cancer due to Helicobacter pylori infection

scientific article

Factors in glucocorticoid regimens associated with treatment response and relapses of IgG4-related disease: a multicentre study

scientific article published on 06 July 2018

Fatal autoimmune hepatitis induced by concurrent loss of naturally arising regulatory T cells and PD-1-mediated signaling

scientific article published on 25 June 2008

Frequent downregulation of the runt domain transcription factors RUNX1, RUNX3 and their cofactor CBFB in gastric cancer.

scientific article

Frequent loss of RUNX3 gene expression in human bile duct and pancreatic cancer cell lines

scientific article published in March 2004

Frequent mutations that converge on the NFKBIZ pathway in ulcerative colitis

scientific article published on 18 December 2019

Future for basic and clinical studies on peptic ulcer disease

scientific article published in March 2004

Gastric MALT lymphomas are divided into three groups based on responsiveness to Helicobacter Pylori eradication and detection of API2-MALT1 fusion.

scientific article published in December 2004

Gastric ulcer and gastroenteritis caused by Epstein-Barr virus during immunosuppressive therapy for a child with systemic juvenile idiopathic arthritis

scientific article published on 15 May 2012

Gastrin stimulates the growth of gastric pit cell precursors by inducing its own receptors

scientific article published on February 2002

Gastroesophageal reflux disease symptoms and dietary behaviors are significant correlates of short sleep duration in the general population: the Nagahama Study

scientific article

Gastrointestinal follicular lymphoma: review of the literature

scientific article published on 20 January 2010

Gastrointestinal manifestation of immunoglobulin G4-related disease: clarification through a multicenter survey.

scientific article

Gene expression profile of Dclk1+ cells in intestinal tumors

scientific article published on 22 June 2018

Generation of pluripotent stem cells from adult mouse liver and stomach cells

scientific article

Genetic alterations leading to the development of colitis-associated colorectal cancers

scientific article published on 01 February 2012

Genetic analysis of a case of Helicobacter pylori-uninfected intramucosal gastric cancer in a family with hereditary diffuse gastric cancer

scientific article published on 12 December 2018

Genetic heterogeneity of hepatitis C virus in association with antiviral therapy determined by ultra-deep sequencing

scientific article

Glycosylation and palmitoylation of Wnt-3a are coupled to produce an active form of Wnt-3a

scientific article published on April 2007

Growth arrest-specific gene 6 and Axl signaling enhances gastric cancer cell survival via Akt pathway

scientific article published on February 2007

Growth promoting effect of thioredoxin on intestinal epithelial cells.

scientific article

Harmonic gray scale 3D contrast imaging of the liver

scientific article published on 01 May 2002

Heat shock protein 47 can be a new target molecule for intestinal fibrosis related to inflammatory bowel disease

scientific article published on 01 December 2010

Helicobacter felis-induced gastritis was suppressed in mice overexpressing thioredoxin-1.

scientific article published in September 2005

Helicobacter pylori immunology and vaccines.

scientific article published on October 2008

Helicobacter pylori in solid-organ transplant recipient.

scientific article published on December 2008

Helicobacter pylori infection triggers aberrant expression of activation-induced cytidine deaminase in gastric epithelium

scientific article published on 01 April 2007

Helicobacter pylori promotes the production of thymic stromal lymphopoietin by gastric epithelial cells and induces dendritic cell-mediated inflammatory Th2 responses

scientific article

Helicobacter pylori-Mediated Genetic Instability and Gastric Carcinogenesis

scientific article published on January 2017

Helicobacter pylori-induced activation-induced cytidine deaminase expression and carcinogenesis ⬇️

scientific article published on August 1, 2010

Helper CD4+ T cells for IgE response to a dietary antigen develop in the liver

scientific article published on 01 June 2003

Hemobilia: another complication associated with anti-thrombotic therapy

scientific article published on 18 December 2010

Heparan sulfate on intestinal epithelial cells plays a critical role in intestinal crypt homeostasis via Wnt/β-catenin signaling

scientific article published on 06 June 2013

Hepatic arterial perfusion increases in the early stage of severe acute pancreatitis patients: Evaluation by perfusion computed tomography ⬇️

scientific article published on November 30, 2010

Hepatic inflammation facilitates transcription-associated mutagenesis via AID activity and enhances liver tumorigenesis

scientific article published on 12 May 2015

Hepatitis B Virus Genotype E Infection among Egyptian Health Care Workers

scientific article published on 30 June 2017

Hepatitis B virus infection in lymphatic tissues in inactive hepatitis B carriers.

scientific article

Hepatitis C virus core protein induces homotolerance and cross-tolerance to Toll-like receptor ligands by activation of Toll-like receptor 2.

scientific article published on September 2010

Hes1 is essential in proliferating ductal cell-mediated development of intrahepatic cholangiocarcinoma

scientific article published on 16 October 2020

Hes1 plays an essential role in Kras-driven pancreatic tumorigenesis

scientific article published on 31 January 2019

Hes1-deficient mice show precocious differentiation of Paneth cells in the small intestine

scientific article published on 01 March 2005

High level of endothelial cell-specific gene expression by a combination of the 5' flanking region and the 5' half of the first intron of the VE-cadherin gene

scientific article published on 3 March 2005

High prevalence of autoantibodies against carbonic anhydrase II and lactoferrin in type 1 diabetes: concept of autoimmune exocrinopathy and endocrinopathy of the pancreas

scientific article published on 01 July 2003

Histology of symptomatic gastroesophageal reflux disease: is it predictive of response to proton pump inhibitors?

scientific article published on March 2013

Host factors are important in determining clinical outcomes of Helicobacter pylori infection.

scientific article

How to diagnose IgG4-related disease

scientific article published on 10 March 2017

Human thioredoxin-1 ameliorates experimental murine colitis in association with suppressed macrophage inhibitory factor production.

scientific article published on 9 August 2006

IFN-γ is reciprocally involved in the concurrent development of organ-specific autoimmunity in the liver and stomach

scientific article published on 13 October 2011

IL-7 produced by thymic epithelial cells plays a major role in the development of thymocytes and TCRγδ+ intraepithelial lymphocytes

scientific article published on 17 May 2013

Identification and characterization of IgG4-associated autoimmune hepatitis

scientific article published on 24 July 2009

Identification of Adipophilin as a Potential Plasma Biomarker for Colorectal Cancer Using Label-Free Quantitative Mass Spectrometry and Protein Microarray ⬇️

scientific article (publication date: October 2011)

Identification of GM-CSF in Paneth cells using single-cell RT-PCR.

scientific article

Identification of a novel autoantibody against pancreatic secretory trypsin inhibitor in patients with autoimmune pancreatitis

scientific article published on 01 July 2006

Identification of a novel enhancer that binds Sp1 and contributes to induction of cold-inducible RNA-binding protein (cirp) expression in mammalian cells ⬇️

scientific article published on October 10, 2012

Identification of a predictive biomarker for hematologic toxicities of gemcitabine

scientific article

IgG4-related autoimmune pancreatitis involving the colonic mucosa

scientific article

Immunogenetic analysis of gastric MALT lymphoma-like lesions induced by Helicobacter pylori infection in neonatally thymectomized mice.

scientific article published in April 2004

Immunoglobulin G4-related gastrointestinal diseases, are they immunoglobulin G4-related diseases?

scientific article

Immunoglobulin VH gene analysis in gastric MALT lymphomas

scientific article

Immunohistochemical analysis of REG Iα expression in ulcerative colitis-associated neoplastic lesions

scientific article published on 21 January 2011

Immunological and molecular analysis of B lymphocytes in low-grade MALT lymphoma of the stomach. Are there any useful markers for predicting outcome after Helicobacter pylori eradication?

scientific article published on 01 January 2002

Immunosuppressive effects of tacrolimus on macrophages ameliorate experimental colitis ⬇️

scientific article published on December 1, 2010

Impact of EUS-FNA for preoperative para-aortic lymph node staging in patients with pancreatobiliary cancer.

scientific article published on 9 March 2016

Impact of Obstructive Sleep Apnea on Liver Fat Accumulation According to Sex and Visceral Obesity

scientific article published on 15 June 2015

Impaired expression of innate immunity-related genes in IgG4-related disease: A possible mechanism in the pathogenesis of IgG4-RD

scientific article published on 11 July 2019

Impairment of aldehyde dehydrogenase 2 increases accumulation of acetaldehyde-derived DNA damage in the esophagus after ethanol ingestion

scientific article

Importance of CXCL16 as a biomarker for granulocytapheresis in patients with Crohnʼs disease ⬇️

scientific article published on 09 March 2011

Importance of diagnosis of concomitant cytomegalovirus infection in patients with intestinal Behçet's disease

scientific article published on 01 June 2008

Importance of early detection of cytomegalovirus infection in refractory inflammatory bowel disease.

scientific article

Improvement of collateral vessels in the vicinity of gastric cardia after endoscopic variceal ligation therapy for esophageal varices.

scientific article published in May 2004

Increased Susceptibility to Autoimmune Gastritis in Thymic Stromal Lymphopoietin Receptor-Deficient Mice ⬇️

scientific article published on November 28, 2011

Indigenous clostridium species regulate systemic immune responses by induction of colonic regulatory T cells

scientific article published on 24 July 2011

Individualized extension of pegylated interferon plus ribavirin therapy for recurrent hepatitis C genotype 1b after living-donor liver transplantation

scientific article published in September 2010

Induction and monitoring of definitive and visceral endoderm differentiation of mouse ES cells

scientific article published on 27 November 2005

Inflammation-associated cancer development in digestive organs: mechanisms and roles for genetic and epigenetic modulation

scientific article published on 13 July 2012

Inflammation‐mediated genomic instability: roles of activation‐induced cytidine deaminase in carcinogenesis ⬇️

scientific article published on May 11, 2012

Inhibitory effects of etodolac, a selective COX-2 inhibitor, on the occurrence of tumors in colitis-induced tumorigenesis model in rats

scientific article

Inhibitory role of Gas6 in intestinal tumorigenesis.

scientific article published on 20 February 2013

Instability of IGF-IGFBP complex as a cause of the different performance of serum and EDTA-plasma after storage: EDTA-plasma is preferable for evaluating bioactive IGF especially in the mouse

scientific article published on 2 July 2015

Interaction of Helicobacter pylori-induced follicular gastritis and autoimmune gastritis in BALB/c mice with post-thymectomy autoimmune gastritis.

scientific article

Interleukin‐21 and tumor necrosis factor‐α are critical for the development of autoimmune gastritis in mice ⬇️

scientific article published on June 1, 2013

Intestinal drug delivery systems with biodegradable microspheres targeting mucosal immune-regulating cells for chronic inflammatory colitis

scientific article

Intestinal epithelial cell-derived IL-15 determines local maintenance and maturation of intraepithelial lymphocytes in the intestine

scientific article published on 26 December 2019

Intragraft expression of recipient-type ABO blood group antigens: long-term follow-up and histological features after liver transplantation

scientific article published on 01 May 2005

Introducing the Professionalism Mini-Evaluation Exercise (P-MEX) in Japan: results from a multicenter, cross-sectional study

scientific article

Investigation of pretreatment prediction of proton pump inhibitor (PPI)-resistant patients with gastroesophageal reflux disease and the dose escalation challenge of PPIs-TORNADO study: a multicenter prospective study by the Acid-Related Symptom Rese

scientific article published on August 24, 2011

Involvement of activation of Toll-like receptors and nucleotide-binding oligomerization domain-like receptors in enhanced IgG4 responses in autoimmune pancreatitis

article

Involvement of activation-induced cytidine deaminase in the development of colitis-associated colorectal cancers ⬇️

scientific article published on September 28, 2010

Involvement of cyclooxygenase-2 in gastric mucosal hypertrophy in gastrin transgenic mice.

scientific article

Involvement of cytomegalovirus infection in the ileal lesions of the patient with Behçet's disease

scientific article published on 01 June 2007

Involvement of gene abnormalities in the development of digestive diseases

scientific article published on January 2016

Involvement of interleukin-17A-induced expression of heat shock protein 47 in intestinal fibrosis in Crohn's disease.

scientific article published on 17 February 2014

Involvement of lupus enteritis in a patient with lupus cystitis and nephritis

scientific article published on 16 September 2009

Involvement of mycobacterium avium subspecies paratuberculosis in TNF-α production from macrophage: Possible link between MAP and immune response in Crohnʼs disease

scientific article

Involvement of myeloid dendritic cells in the development of gastric secondary lymphoid follicles in Helicobacter pylori-infected neonatally thymectomized BALB/c mice.

scientific article

Involvement of the IL-22/REG Ialpha axis in ulcerative colitis

scientific article

It is possible to classify non-erosive reflux disease (NERD) patients into endoscopically normal groups and minimal change groups by subjective symptoms and responsiveness to rabeprazole -- a report from a study with Japanese patients

scientific article published on 9 May 2008

Key molecules in metaplastic gastritis: sequential analysis of CDX1/2 homeobox gene expression

scientific article published on 01 January 2002

Laminin 511 is a target antigen in autoimmune pancreatitis

scientific article published on 01 August 2018

Landscape of Genetic Aberrations Detected in Human Colorectal Cancers ⬇️

scientific article published on July 25, 2013

Lansoprazole for secondary prevention of gastric or duodenal ulcers associated with long-term low-dose aspirin therapy: results of a prospective, multicenter, double-blind, randomized, double-dummy, active-controlled trial ⬇️

scientific article published on April 16, 2011

Large-Scale Identification of Effector Genes That Mediate the Type I Interferon Antiviral Response ⬇️

scientific article published on November 19, 2011

Late-onset acetaminophen-induced allergic hepatitis with progression to chronicity

scientific article published on 02 September 2014

Lens culinaris agglutinin-A-reactive alpha-fetoprotein as a marker for liver atrophy in fulminant hepatic failure

scientific article published on 01 June 2003

Leptin receptor somatic mutations are frequent in HCV-infected cirrhotic liver and associated with hepatocellular carcinoma.

scientific article

Ligand-specific antibodies to insulin-like growth factors suppress intestinal polyp formation in Apc+/- mice

scientific article

Limited benefit of biochemical response to combination therapy for patients with recurrent hepatitis C after living-donor liver transplantation

scientific article published in March 2008

Lineage tracing and targeting of IL17RB+ tuft cell-like human colorectal cancer stem cells

scientific article published on 10 June 2019

Liver targeting of human interferon-beta with pullulan based on metal coordination

scientific article published in September 2002

Localization of calcitonin gene-related peptide receptors in rat gastric mucosa

scientific article published in May 2002

Localized cytomegalovirus reactivation after radiotherapy for high-grade gastric lymphoma

scientific article published on 01 March 2007

Long-term efficacy of hepatitis B vaccination as post-transplant prophylaxis in hepatitis B surface antigen (HBsAg) positive recipients and HBsAg negative recipients of anti-hepatitis B core positive grafts

scientific article published on 8 September 2015

Long-term outcome of transoral organ-preserving pharyngeal endoscopic resection for superficial pharyngeal cancer.

scientific article published on 25 June 2011

Loss of RUNX3 expression by histone deacetylation is associated with biliary tract carcinogenesis ⬇️

scientific article published on February 10, 2011

Loss of function of the candidate tumor suppressor prox1 by RNA mutation in human cancer cells

scientific article published on December 2006

Loss of the major duodenal papilla results in brown pigment biliary stone formation in pdx1 null mice

scientific article published in March 2006

Low prevalence of CMV infection in patients with Crohn's disease in comparison with ulcerative colitis: effect of different immune response on prevalence of CMV infection

scientific article published on 01 May 2010

Low-dose maintenance steroid treatment could reduce the relapse rate in patients with type 1 autoimmune pancreatitis: a long-term Japanese multicenter analysis of 510 patients

scientific article published on 6 January 2017

MCAF mediates MBD1-dependent transcriptional repression

scientific article

MSH2 Dysregulation Is Triggered by Proinflammatory Cytokine Stimulation and Is Associated with Liver Cancer Development

scientific article published on 3 June 2016

Magnified endoscopic view of primary follicular lymphoma at the duodenal papilla

scientific article published on 01 February 2007

Magnifying narrow-band imaging versus magnifying white-light imaging for the differential diagnosis of gastric small depressive lesions: a prospective study

scientific article published on 01 March 2010

Management and clinical outcomes of type I gastric carcinoid patients: retrospective, multicenter study in Japan

scientific article published on 05 November 2013

Massive jejunal bleeding due to Heyde syndrome successfully treated with double balloon endoscopy

scientific article published on 19 March 2009

Matrix metalloproteinase-7 degrades all insulin-like growth factor binding proteins and facilitates insulin-like growth factor bioavailability

scientific article published on August 2005

Matrix metalloproteinase-7 facilitates insulin-like growth factor bioavailability through its proteinase activity on insulin-like growth factor binding protein 3.

scientific article published on January 2004

Matrix metalloproteinase-7 triggers the matricrine action of insulin-like growth factor-II via proteinase activity on insulin-like growth factor binding protein 2 in the extracellular matrix.

scientific article published on 14 March 2007

Measurement of canine pancreatic perfusion using dynamic computed tomography: influence of input-output vessels on deconvolution and maximum slope methods.

scientific article published on 18 July 2009

Mechanism for gastric cancer development by Helicobacter pylori infection.

scientific article published on 10 June 2008

Mediterranean mimicker ⬇️

scientific article published on December 8, 2012

Metastatic thyroid lymphoma

scientific article published on 01 October 2004

Methyl-CpG binding domain 1 (MBD1) interacts with the Suv39h1-HP1 heterochromatic complex for DNA methylation-based transcriptional repression

scientific article

Modulation of Th1/Th2 balance by infliximab rescues postoperative occurrence of small-intestinal inflammation associated with ulcerative colitis

scientific article published on 12 August 2009

Modulation of VEGFR-2-mediated endothelial-cell activity by VEGF-C/VEGFR-3.

scientific article published on 10 October 2002

Modulation of the Th1/Th2 balance by infliximab improves hyperthyroidism associated with a flare-up of ulcerative colitis

scientific article published on 01 July 2009

Molecular Pathogenesis of Helicobacter pylori-Related Gastric Cancer

scientific article published on 07 July 2015

Molecular changes leading to gastric cancer: a suggestion from rare-type gastric tumors with GNAS mutations

scientific article published on 25 March 2014

Molecular mechanisms of portal vein tolerance

Mouse models of hepatitis B virus infection comprising host-virus immunologic interactions

scientific article

Mucocele of the appendix due to endometriosis: a rare case report

scientific article published on August 2013

Multinational, double-blind, randomised, placebo-controlled, prospective study of esomeprazole in the prevention of recurrent peptic ulcer in low-dose acetylsalicylic acid users: the LAVENDER study.

scientific article published on 10 December 2013

Multiple roles of SIM2 in esophageal squamous cell carcinoma and its clinical implications.

scientific article published on 10 February 2018

NOD1 contributes to mouse host defense against Helicobacter pylori via induction of type I IFN and activation of the ISGF3 signaling pathway

scientific article

NOD1-Mediated Mucosal Host Defense against Helicobacter pylori ⬇️

scientific article published on July 15, 2010

Nardilysin and ADAM proteases promote gastric cancer cell growth by activating intrinsic cytokine signalling via enhanced ectodomain shedding of TNF-α.

scientific article

Nardilysin controls intestinal tumorigenesis through HDAC1/p53-dependent transcriptional regulation.

scientific article published on 19 April 2018

Nardilysin inhibits pancreatitis and suppresses pancreatic ductal adenocarcinoma initiation in mice

article published in 2018

Nardilysin inhibits pancreatitis and suppresses pancreatic ductal adenocarcinoma initiation in mice

Nardilysin regulates inflammation, metaplasia, and tumors in murine stomach

scientific article

Narrow-band imaging of the gastrointestinal tract.

scientific article published on 22 January 2009

Neutrophil-to-lymphocyte ratio for predicting palliative chemotherapy outcomes in advanced pancreatic cancer patients

scientific article

New cytokine delivery system using gelatin microspheres containing interleukin-10 for experimental inflammatory bowel disease

scientific article published on 01 April 2002

Novel 5-fluorouracil-resistant human esophageal squamous cell carcinoma cells with dihydropyrimidine dehydrogenase overexpression.

scientific article

Novel EGFR-targeted strategy with hybrid peptide against oesophageal squamous cell carcinoma.

scientific article published on 09 March 2016

Novel genetic mutations specific for intraductal papillary neoplasm of the pancreas

scientific article published on 25 April 2012

Novel interleukin-4 and interleukin-1 receptor antagonist gene variations associated with non-cardia gastric cancer in Japan: comprehensive analysis of 207 polymorphisms of 11 cytokine genes

scientific article published on 01 May 2007

Novel mouse models of hepatocarcinogenesis with stepwise accumulation of genetic alterations

scientific article

Nuclear beta-catenin accumulation as a prognostic factor in Dukes' D human colorectal cancers

scientific article published on August 2004

Open label trial of clarithromycin therapy in Japanese patients with Crohn's disease

scientific article published on 01 July 2007

Organ-specific profiles of genetic changes in cancers caused by activation-induced cytidine deaminase expression

scientific article

Osteopontin Deficiency Accelerates Spontaneous Colitis in Mice with Disrupted Gut Microbiota and Macrophage Phagocytic Activity

scientific article published on 14 August 2015

Overexpression of redox-active protein thioredoxin-1 prevents development of chronic pancreatitis in mice

scientific article published on 01 September 2006

Overexpression of regenerating gene Iα appears to reflect aberration of crypt cell compartmentalization in sessile serrated adenoma/polyps of the colon

scientific article

Oxaliplatin-Free Interval as a Risk Factor for Hypersensitivity Reaction among Colorectal Cancer Patients Treated with FOLFOX ⬇️

scientific article published on December 8, 2010

Pathogenicity of IgG in patients with IgG4-related disease.

scientific article published on 10 March 2016

Perfusion CT is superior to angiography in predicting pancreatic necrosis in patients with severe acute pancreatitis

scientific article published on 13 July 2010

Perfusion computed tomography findings of autoimmune pancreatitis

scientific article published in November 2011

Perfusion computerized tomography can predict pancreatic necrosis in early stages of severe acute pancreatitis

scientific article published on 22 October 2007

Perfusion in the tissue surrounding pancreatic cancer and the patient's prognosis.

scientific article

Periportal and sinusoidal liver dendritic cells suppressing T helper type 1-mediated hepatitis

scientific article published on October 2007

Perivascular epithelioid cell tumor (PEComa) of the liver diagnosed by contrast-enhanced ultrasonography.

scientific article

Pharmacokinetics of oxaliplatin in a hemodialytic patient treated with modified FOLFOX-6 plus bevacizumab therapy

scientific article published on 16 April 2011

Phenotyping of IgG4-related diseases based on affected organ pattern: A multicenter cohort study using cluster analysis

scientific article published on 04 January 2020

Plasma cell hepatitis induced by the termination of antiviral therapy for recurrent hepatitis C after living donor liver transplantation

scientific article published on 25 November 2013

Plasmacytoid Dendritic Cell Activation and IFN-α Production Are Prominent Features of Murine Autoimmune Pancreatitis and Human IgG4-Related Autoimmune Pancreatitis.

scientific article published on 21 August 2015

Platelet Plays a Role in the Pathogenesis of Hepatitis B Virus–Related Hepatocellular Carcinoma ⬇️

scientific article published on March 22, 2013

Positive finding of colonic polymerase chain reaction for cytomegalovirus DNA is not false positive but a warning for treating patients with ulcerative colitis refractory to immunosuppressive therapies.

scientific article

Possible involvement of RUNX3 silencing in the peritoneal metastases of gastric cancers

scientific article

Possible involvement of T helper type 2 responses to Toll-like receptor ligands in IgG4-related sclerosing disease

article

Possible link between ulcerative colitis and in situ adenocarcinoma of an appendiceal mucocele: importance of inflammation in the appendiceal orifice related to UC

scientific article published on 01 June 2008

Preclinical validation of talaporfin sodium-mediated photodynamic therapy for esophageal squamous cell carcinoma.

scientific article

Predicting the efficacy of proton pump inhibitors in patients with non‐erosive reflux disease before therapy using dual‐channel 24‐h esophageal pH monitoring ⬇️

scientific article published on May 1, 2012

Pretransplant serum hepatitis C virus RNA levels predict response to antiviral treatment after living donor liver transplantation

scientific article

Prevalence of esophageal candidiasis among patients treated with inhaled fluticasone propionate

scientific article published in October 2003

Primary gastrointestinal follicular lymphoma involving the duodenal second portion is a distinct entity: a multicenter, retrospective analysis in Japan

scientific article published on 15 June 2011

Primary localized amyloidosis of the duodenum

scientific article published on 01 February 2007

Prior use of immunomodulatory drugs improves the clinical outcome of endoscopic balloon dilation for intestinal stricture in patients with Crohn's disease ⬇️

scientific article published on January 29, 2013

Prognostic model for survival based on readily available pretreatment factors in patients with advanced pancreatic cancer receiving palliative chemotherapy.

scientific article

Progression of autoimmune hepatitis is mediated by IL-18-producing dendritic cells and hepatic CXCL9 expression in mice

scientific article

Prohormone convertase furin has a role in gastric cancer cell proliferation with parathyroid hormone-related peptide in a reciprocal manner

scientific article published on December 2002

Proinflammatory Th2 cytokines induce production of thymic stromal lymphopoietin in human colonic epithelial cells

scientific article published on 16 September 2009

Proliferating EpCAM-Positive Ductal Cells in the Inflamed Liver Give Rise to Hepatocellular Carcinoma

scientific article published on 26 September 2017

Protective role of ALDH2 against acetaldehyde-derived DNA damage in oesophageal squamous epithelium

scientific article

Protective role of thioredoxin-1 in Helicobacter felis-induced gastritis

scientific article published in November 2005

Protective roles of redox-active protein thioredoxin-1 for severe acute pancreatitis

scientific article published in December 2005

Pseudo-Meigs' syndrome caused by a Krukenberg tumour of gastric cancer

scientific article published on 15 October 2015

Quantitative analysis of tumor-derived methylated RUNX3 sequences in the serum of gastric cancer patients.

scientific article

REG (regenerating gene) protein--roles of REG protein in H. pylori-induced gastritis and gastric cancers

scientific article

REG Ialpha protein may function as a trophic and/or anti-apoptotic factor in the development of gastric cancer.

scientific article

REG Ialpha protein mediates an anti-apoptotic effect of STAT3 signaling in gastric cancer cells

scientific article published on 16 November 2007

RUNX3 promoter methylation in colorectal cancer: its relationship with microsatellite instability and its suitability as a novel serum tumor marker

scientific article published on July 1, 2010

Rapid development of diffuse large B-Cell lymphoma after successful eradication of Helicobacter pylori for gastric MALT lymphoma

scientific article published on 06 October 2006

Rat gastric mucosal epithelial cell culture

scientific article

Rb and p53 execute distinct roles in the development of pancreatic neuroendocrine tumors

scientific article published on 26 June 2020

Reactivation from occult HBV carrier status is characterized by low genetic heterogeneity with the wild-type or G1896A variant prevalence

scientific article published on 4 May 2014

Recent advances in the immunopathogenesis of inflammatory bowel diseases

scientific article published on 01 February 2012

Rectal carcinoid tumor mimicking colonic adenomatous lesion

scientific article published on 01 December 2005

Recurrent somatic mutations in human gastric cancers identified by whole exome sequencing

scientific article published on 21 September 2012

Reduced Numbers and Proapoptotic Features of Mucosal-associated Invariant T Cells as a Characteristic Finding in Patients with Inflammatory Bowel Disease

scientific article published on July 2015

Reduced plasma level of CXC chemokine ligand 7 in patients with pancreatic cancer

scientific article published on 08 December 2010

Reduction of Ptf1a gene dosage causes pancreatic hypoplasia and diabetes in mice

scientific article published on 30 June 2008

Refractoriness of intestinal Behçet's disease with myelodysplastic syndrome involving trisomy 8 to medical therapies - our case experience and review of the literature

scientific article

Refractory enterovesical and duodenocolic fistulas in Crohn's disease successfully managed with tacrolimus

scientific article published in April 2005

Reg protein is a unique growth factor of gastric mucosal cells

scientific article published in June 2004

Reg protein is overexpressed in gastric cancer cells, where it activates a signal transduction pathway that converges on ERK1/2 to stimulate growth

scientific article published in October 2002

Regression of Hodgkin lymphoma in response to antiviral therapy for hepatitis C virus infection

scientific article published in October 2012

Regression of MALT lymphomas coexisting in the duodenal bulb and the stomach by eradication of Helicobacter pylori

scientific article published on 01 January 2002

Regular arrangement of collecting venules: Does patient age affect its accuracy?

scientific article

Relationship between pancreatic perfusion parameters and clinical complications of severe acute pancreatitis

scientific article published on 01 January 2013

Relationship between serum angiopoietin-2 level and perfusion CT parameters in severe acute pancreatitis

scientific article published in October 2011

Repeated administration of ghrelin to patients with functional dyspepsia: its effects on food intake and appetite.

scientific article published in April 2008

Rescue therapy with tacrolimus for a patient with severe ulcerative colitis refractory to combination leukocytapheresis and high-dose corticosteroid therapy

scientific article published on 01 June 2007

Resection for hepatocellular carcinoma with duodenal invasion: report of a case

scientific article published on 01 July 2003

Restoration of RUNX3 enhances transforming growth factor-beta-dependent p21 expression in a biliary tract cancer cell line.

scientific article published on June 2007

Retroflexed endoscopic multiple band ligation of symptomatic internal hemorrhoids

scientific article published in March 2004

Retrospective analysis of 27 consecutive patients treated with docetaxel/nedaplatin combination therapy as a second-line regimen for advanced esophageal cancer

scientific article

Risk Factors for Pancreatic Stone Formation in Type 1 Autoimmune Pancreatitis: A Long-term Japanese Multicenter Analysis of 624 Patients

scientific article published on 01 January 2019

Risk of cancer in patients with autoimmune pancreatitis

scientific article published on 15 January 2013

Role of Activation-Induced Cytidine Deaminase in Inflammation-Associated Cancer Development

scientific article published on January 1, 2011

Role of a novel oncogenic protein, gankyrin, in hepatocyte proliferation ⬇️

scientific article published on January 1, 2003

Role of heat shock protein 47 in intestinal fibrosis of experimental colitis ⬇️

scientific article published on December 6, 2010

SR-PSOX/CXCL16 plays a critical role in the progression of colonic inflammation ⬇️

scientific article published on 06 April 2011

STAT3 is constitutively activated and supports cell survival in association with survivin expression in gastric cancer cells.

scientific article published on June 2004

Safety and efficacy of modified FOLFOX6 for treatment of metastatic or locally advanced colorectal cancer. A single-institution outcome study.

scientific article

Safety and pharmacokinetics of recombinant human hepatocyte growth factor (rh-HGF) in patients with fulminant hepatitis: a phase I/II clinical trial, following preclinical studies to ensure safety.

scientific article

Scintigraphic study of regenerative nodules due to fulminant hepatic failure

scientific article published in January 2003

Second Asia-Pacific Consensus Guidelines for Helicobacter pylori infection

scientific article published on October 2009

Sensing of commensal organisms by the intracellular sensor NOD1 mediates experimental pancreatitis

scientific article

Serum miR-21, miR-29a, and miR-125b Are Promising Biomarkers for the Early Detection of Colorectal Neoplasia

scientific article

Serum soluble interleukin-2 receptor as a biomarker in immunoglobulin G4-related disease

scientific article published on 18 December 2017

Siah-1L, a novel transcript variant belonging to the human Siah family of proteins, regulates beta-catenin activity in a p53-dependent manner.

scientific article

Signal transducers and activators of transcription 3 activation is involved in nuclear accumulation of beta-catenin in colorectal cancer

scientific article published on March 2006

Simultaneous occurrence of inflammatory bowel disease and myelodysplastic syndrome due to chromosomal abnormalities in bone marrow cells

scientific article

Slow Progression of Poorly Differentiated Gastric Carcinoma Associated with Epstein-Barr Virus Infection: 12-year Follow-up

scientific article published on 15 June 2015

Small bowel anisakiasis with self-limiting clinical course

scientific article published on 15 December 2008

Small intestine Peyer's patches are major induction sites of the Helicobacter-induced host immune responses

scientific article published on 01 February 2008

Solitary rectal ulcer syndrome associated with ulcerative colitis.

scientific article

Sox9-dependent acinar-to-ductal reprogramming is critical for pancreatic intraepithelial neoplasia formation

scientific article

Specific antibodies against recombinant protein of insertion element 900 of Mycobacterium avium subspecies paratuberculosis in Japanese patients with Crohn's disease

scientific article published in January 2006

Splenectomy Prolongs the Effects of Corticosteroids in Mouse Models of Autoimmune Hepatitis ⬇️

scientific article published on March 19, 2013

Spontaneous regression of Epstein-Barr virus-associated T-cell lymphoma of the stomach.

scientific article

Spontaneous rupture of a biliary diverticulum in the distal common bile duct, with formation of a retroperitoneal biloma

scientific article published in May 2005

Spontaneous rupture of liver plasmacytoma mimicking hepatocellular carcinoma

scientific article published on 01 April 2010

Stability of acetaldehyde-derived DNA adduct in vitro ⬇️

scientific article published on June 5, 2012

Strategies for improving outcomes for gastric cancer

scientific article published on 01 July 2007

Successful telaprevir treatment in combination of cyclosporine against recurrence of hepatitis C in the Japanese liver transplant patients

scientific article published on 26 December 2013

Survival prediction for pancreatic cancer patients receiving gemcitabine treatment

scientific article

Sustained abdominal discomfort in a 57-year-old woman. Idiopathic mesenteric phlebosclerosis

scientific article published on 01 May 2010

Systematic review: cytomegalovirus infection in inflammatory bowel disease

scientific article published on 29 October 2008

TERT promoter mutations and chromosome 8p loss are characteristic of nonalcoholic fatty liver disease-related hepatocellular carcinoma

scientific article published on 11 August 2016

TNF-alpha is an important pathogenic factor contributing to reactivation of cytomegalovirus in inflamed mucosa of colon in patients with ulcerative colitis: lesson from clinical experience.

scientific article

TNF-α is essential in the induction of fatal autoimmune hepatitis in mice through upregulation of hepatic CCL20 expression ⬇️

scientific article published on November 7, 2012

Tacrolimus Therapy as an Alternative to Thiopurines for Maintaining Remission in Patients With Refractory Ulcerative Colitis ⬇️

scientific article published on 01 July 2011

Th response to Helicobacter pylori differs between patients with gastric ulcer and duodenal ulcer

scientific article published on 01 June 2005

The "scarf-ring sign" of ball valve syndrome

scientific article published on 01 April 2002

The BRG1/SOX9 axis is critical for acinar cell-derived pancreatic tumorigenesis

article by Motoyuki Tsuda et al published 1 August 2018 in Journal of Clinical Investigation

The aryl hydrocarbon receptor nuclear transporter is modulated by the SUMO-1 conjugation system

scientific article

The cutting-edge of medicine; inflammation and development of gastrointestinal cancers ⬇️

scientific article published on August 10, 2011

The effect of medical treatment on patients with fistulizing Crohn's disease: a retrospective study

scientific article published on 15 February 2008

The effect of tacrolimus (FK-506) on Japanese patients with refractory Crohn's disease.

scientific article published on 29 October 2008

The implications of myelodysplastic syndrome - associated chromosomal abnormalities in the development of graft-versus-host disease

article

The radiological exposure of pancreatic perfusion computed tomography

scientific article published on 01 May 2010

The role of Hes genes in intestinal development, homeostasis and tumor formation.

scientific article published on 8 February 2012

The role of innate immunity in the pathogenesis of experimental autoimmune pancreatitis in mice.

scientific article published in January 2011

The role of notch signaling in the development of intrahepatic bile ducts

scientific article

Therapeutic effects of famotidine on chronic symptomatic gastritis: subgroup analysis from FUTURE study ⬇️

scientific article published on December 21, 2011

Therapeutic effects of rectal administration of basic fibroblast growth factor on experimental murine colitis.

scientific article published in April 2005

Therapeutic efficacy of infliximab on patients with short duration of Crohn's disease: a Japanese multicenter survey

scientific article published on 06 March 2008

Tissue Damage in the Canine Normal Esophagus by Photoactivation with Talaporfin Sodium (Laserphyrin): A Preclinical Study ⬇️

scientific article published on June 13, 2012

Toll-like receptor activation in basophils contributes to the development of IgG4-related disease

scientific article published on 29 June 2012

Training of medical team

scientific article published on April 1, 2013

Transgenic overexpression of Reg protein caused gastric cell proliferation and differentiation along parietal cell and chief cell lineages

scientific article

Translational research on HGF: A phase I/II study of recombinant human HGF for the treatment of fulminant hepatic failure

scientific article published on 01 November 2008

Transpapillary biliary biopsy for early stage cholangiocarcinoma of the distal common bile duct

scientific article published on 01 July 2006

Treatment of advanced tumors with agonistic anti-GITR mAb and its effects on tumor-infiltrating Foxp3+CD25+CD4+ regulatory T cells.

scientific article

Treatment of advanced tumors with agonistic anti-GITR mAb and its effects on tumor-infiltrating Foxp3CD25CD4 regulatory T cells

scientific article published in February 2012

Tumor thrombi in the portal vein system originating from gastrointestinal tract cancer

scientific article published on 01 January 2002

Tumors of the biliary tract and pancreas

scientific article published on 01 August 2010

Ultrasound exposure enhances the biological action of interferon in the liver

Up-regulation of activation-induced cytidine deaminase causes genetic aberrations at the CDKN2b-CDKN2a in gastric cancer

scientific article published on 14 July 2010

Upregulation of T-bet and tight junction molecules by Bifidobactrium longum improves colonic inflammation of ulcerative colitis

scientific article published on 01 November 2009

Usefulness of endoscopic radial incision and cutting method for refractory esophagogastric anastomotic stricture (with video).

scientific article published in May 2012

Usefulness of quantitative real-time PCR assay for early detection of cytomegalovirus infection in patients with ulcerative colitis refractory to immunosuppressive therapies

scientific article published on 01 December 2007

Validity of endoscopic classification of nonerosive reflux disease

scientific article published on 29 June 2007

Visualization of stem cell activity in pancreatic cancer expansion by direct lineage tracing with live imaging

scientific article published on 04 January 2021

What are the real roles of different erbB proteins in Barrett's Esophagus

scientific article published on 16 September 2004

What is responsible for the development of the distinctive pattern of gastritis induced by Helicobacter pylori infection?

scientific article published in January 2004

Wnt/beta-catenin signaling suppresses apoptosis in low serum medium and induces morphologic change in rodent fibroblasts

scientific article published on June 2002

[Diagnosis and treatment for superficial cancer in the oropharynx and hypopharynx: new strategy of early detection and minimally invasive treatment]

scientific article published on 01 September 2009

[Diagnosis and treatment of gastric MALT lymphoma]

scientific article published on 01 May 2003

[Epidemiology of peptic ulcer]

scientific article published on 01 February 2002

[Etiopathogenesis and aggravating factors in ulcerative colitis]

scientific article published on 01 May 2005

[Evaluation of the safety and efficacy of endoscopic treatment for early gastric cancers in patients aged over 80 years]

scientific article published on 01 January 2018

[Histopathology of peptic ulcers]

scientific article published on 01 February 2002

[Non-epithelial tumors of the small intestine]

scientific article published on 01 January 2011

[PPI treatment for gastric ulcer patients in the elderly]

scientific article published on 01 November 2010

[Pathogenesis of gastric and duodenal ulcer in the elderly]

scientific article published on 01 August 2002

[Prevention and treatment of nonsteroidal anti-inflammatory drug-induced gastric ulcers with proton pump inhibitor]

scientific article published on 01 October 2007

[The cutting-edge of medicine; clinical features and diagnosis of IgG4-related disease (IgG4-RD)]

scientific article published on 01 October 2012

[The definition of Barrett's esophagus]

scientific article published on 01 August 2005

[The involvement of cytomegalovirus infection in the patient with intestinal Behçet's disease]

scientific article published on 01 December 2008

[Treatment for peptic ulcer disease in the elderly patients--from new guideline for treatment of gastric ulcer based on EBM]

scientific article published on 01 September 2004

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