List of works - Hiroshi Ikeda

5-Azacytidine, a DNA methyltransferase inhibitor, induces ATR-mediated DNA double-strand break responses, apoptosis, and synergistic cytotoxicity with doxorubicin and bortezomib against multiple myeloma cells.

scientific article

A Multicenter Retrospective Study of Mogamulizumab Efficacy in Adult T-Cell Leukemia/Lymphoma

scientific article published on 17 September 2016

A case of adult T cell leukemia/lymphoma presenting as severe tracheal stenosis

scientific article published on 01 November 2011

A case of primary mediastinal (Thymic) B-cell lymphoma successfully treated with the DA-EPOCH-R Regimen

scientific article published in January 2015

A novel Aurora-A kinase inhibitor MLN8237 induces cytotoxicity and cell-cycle arrest in multiple myeloma

scientific article

A proto-oncogene BCL6 is up-regulated in the bone marrow microenvironment in multiple myeloma cells

scientific article

Allogeneic bone marrow transplantation in a patient with primary hepatic diffuse large B-cell lymphoma that relapsed after autologous stem cell transplantation

scientific article published on 01 September 2014

Assessment of prognosis in immunoglobulin light chain amyloidosis patients with severe heart failure: a predictive value of right ventricular function

scientific article published on 26 September 2019

Autologous stem cell transplantation for AL amyloidosis: adjustment of melphalan dose by factors including BNP.

scientific article published on 4 October 2014

BCL9 promotes tumor progression by conferring enhanced proliferative, metastatic, and angiogenic properties to cancer cells

scientific article

BIRB 796 enhances cytotoxicity triggered by bortezomib, heat shock protein (Hsp) 90 inhibitor, and dexamethasone via inhibition of p38 mitogen-activated protein kinase/Hsp27 pathway in multiple myeloma cell lines and inhibits paracrine tumour growth

scientific article published on 14 December 2006

Biologic sequelae of I{kappa}B kinase (IKK) inhibition in multiple myeloma: therapeutic implications

scientific article published on 06 March 2009

Blockade of XBP1 splicing by inhibition of IRE1α is a promising therapeutic option in multiple myeloma

scientific article

Bortezomib induces canonical nuclear factor-kappaB activation in multiple myeloma cells

scientific article published on 12 May 2009

Bortezomib plus dexamethasone treatment followed by reduced-intensity allogeneic stem cell transplantation for multiple myeloma refractory to high-dose chemotherapy with autologous transplantation

scientific article published on 01 March 2011

Cardiac Light Chain Deposition Disease Mimicking Immunoglobulin Light Chain Amyloidosis: Two Branches of the Same Tree

scientific article published on 02 September 2020

Coadministration of tenofovir decreased atazanavir plasma concentration after unilateral nephrectomy ⬇️

scientific article published on 05 October 2012

Correction: Genomic vulnerability to LINE-1 hypomethylation is a potential determinant of the clinicogenetic features of multiple myeloma

scientific article

DOT1L inhibition blocks multiple myeloma cell proliferation by suppressing IRF4-MYC signaling

scholarly article by Kazuya Ishiguro et al published January 2019 in Haematologica

Decrease of B-type natriuretic peptide to less than 200 pg/mL predicts longer survival in cardiac immunoglobulin light chain amyloidosis

scientific article published on 28 May 2015

Dual inhibition of akt/mammalian target of rapamycin pathway by nanoparticle albumin-bound-rapamycin and perifosine induces antitumor activity in multiple myeloma.

scientific article published on 6 April 2010

EPO-R+ myelodysplastic cells with ring sideroblasts produce high erythroferrone levels to reduce hepcidin expression in hepatic cells

scientific article published on 30 April 2019

Effective combination therapy of bortezomib and dexamethasone for two patients with refractory multiple myeloma

scientific article

Elevation of Plasmin-α2-plasmin Inhibitor Complex Predicts the Diagnosis of Systemic AL Amyloidosis in Patients with Monoclonal Protein

scientific article

Exceptionally rapid response to pembrolizumab in a SMARCA4-deficient thoracic sarcoma overexpressing PD-L1: A case report

scientific article published on 16 October 2019

Fatty acid synthase is a novel therapeutic target in multiple myeloma

scientific article published on 10 April 2008

Genomic vulnerability to LINE-1 hypomethylation is a potential determinant of the clinicogenetic features of multiple myeloma.

scientific article

High dose of Zoledronic acid inhibits both osteoclasts and osteoblasts in an In Vivo mouse model

High-dose zoledronic acid impacts bone remodeling with effects on osteoblastic lineage and bone mechanical properties

scientific article

IKKβ inhibitor in combination with bortezomib induces cytotoxicity in breast cancer cells

scientific article published on 23 January 2014

Inhibition of Akt induces significant downregulation of survivin and cytotoxicity in human multiple myeloma cells

scientific article published on September 2007

Long-term prognosis of patients with HHV-6 reactivation following allogeneic HSCT.

scientific article published on 14 March 2018

MLN3897, a novel CCR1 inhibitor, impairs osteoclastogenesis and inhibits the interaction of multiple myeloma cells and osteoclasts.

scientific article

Model of translational cancer research in multiple myeloma ⬇️

scientific article published on August 17, 2012

Molecular diagnostics of a single drug-resistant multiple myeloma case using targeted next-generation sequencing.

scientific article published on 5 October 2015

Nifuroxazide inhibits survival of multiple myeloma cells by directly inhibiting STAT3.

scientific article

Occurrence of the African subgroup (Ia) of BK polyomavirus in younger Japanese children

scientific article published in June 2009

Other Iatrogenic Immunodeficiency-associated Lymphoproliferative Disorder Presenting as Primary Bone Lymphoma in a Patient with Rheumatoid Arthritis.

scientific article

PI3K/p110{delta} is a novel therapeutic target in multiple myeloma

scientific article

Plasma tenofovir trough concentrations are associated with renal dysfunction in Japanese patients with HIV infection: a retrospective cohort study

scientific article published on 22 September 2016

Pneumothorax as an Adverse Event in Patients with Lung Metastasis of Soft Tissue Sarcoma under Eribulin Treatment

scientific article published on 27 June 2019

Possible clinical outcomes using early enteral nutrition in individuals with allogeneic hematopoietic stem cell transplantation: A single-center retrospective study

scientific article published on 23 November 2020

Quantification of BK polyoma viruria in Japanese children and adults with hemorrhagic cystitis complicating stem cell transplantation

scientific article published on 01 December 2008

Quantification of adenovirus species B and C viremia by real-time PCR in adults and children undergoing stem cell transplantation.

scientific article published on March 2007

SNX-2112, a selective Hsp90 inhibitor, potently inhibits tumor cell growth, angiogenesis, and osteoclastogenesis in multiple myeloma and other hematologic tumors by abrogating signaling via Akt and ERK

scientific article published on 23 October 2008

Severe adverse events by tyrosine kinase inhibitors decrease survival rates in patients with newly diagnosed chronic phase chronic myeloid leukemia.

scientific article published on 16 April 2018

Small molecule CP-31398 induces reactive oxygen species-dependent apoptosis in human multiple myeloma

scientific article published on 22 July 2017

Sustained complete molecular remission after cessation of imatinib mesylate treatment in a patient with relapsed chronic myelogenous leukemia after allogeneic stem cell transplantation

scientific article published on 01 February 2012

The monoclonal antibody nBT062 conjugated to cytotoxic Maytansinoids has selective cytotoxicity against CD138-positive multiple myeloma cells in vitro and in vivo

scientific article

The role of T-fimbrin in the response to DNA damage: silencing of T-fimbrin by small interfering RNA sensitizes human liver cancer cells to DNA-damaging agents

scientific article

Usefulness of serum free light-chain assay for evaluation of therapeutic efficacy in non-secretory multiple myeloma

scientific article published on January 1, 2013

[Diffuse large B cell lymphoma with HIV infection presented with disseminated thromboembolism during antiretroviral therapy]

scientific article published on 01 January 2020

[Long-term survival after autologous peripheral blood stem cell transplantation in a patient with primary AL amyloidosis complicating congestive heart failure]

scientific article published on 01 November 2007

[Successful treatment with thalidomide-combined therapy in an amyloidosis-complicated multiple myeloma patient refractory to bortezomib, lenalidomide, and pomalidomide]

scientific article published on 01 January 2018

[Treatment of POEMS syndrome with lenalidomide and dexamethasone]

scientific article published on 01 January 2019

miR-7977 inhibits the Hippo-YAP signaling pathway in bone marrow mesenchymal stromal cells

scientific article published on 05 March 2019

List of works by Hiroshi Ikeda

5-Azacytidine, a DNA methyltransferase inhibitor, induces ATR-mediated DNA double-strand break responses, apoptosis, and synergistic cytotoxicity with doxorubicin and bortezomib against multiple myeloma cells.

A Multicenter Retrospective Study of Mogamulizumab Efficacy in Adult T-Cell Leukemia/Lymphoma

A case of adult T cell leukemia/lymphoma presenting as severe tracheal stenosis

A case of primary mediastinal (Thymic) B-cell lymphoma successfully treated with the DA-EPOCH-R Regimen

A novel Aurora-A kinase inhibitor MLN8237 induces cytotoxicity and cell-cycle arrest in multiple myeloma

A proto-oncogene BCL6 is up-regulated in the bone marrow microenvironment in multiple myeloma cells

Allogeneic bone marrow transplantation in a patient with primary hepatic diffuse large B-cell lymphoma that relapsed after autologous stem cell transplantation

Assessment of prognosis in immunoglobulin light chain amyloidosis patients with severe heart failure: a predictive value of right ventricular function

Autologous stem cell transplantation for AL amyloidosis: adjustment of melphalan dose by factors including BNP.

BCL9 promotes tumor progression by conferring enhanced proliferative, metastatic, and angiogenic properties to cancer cells

BIRB 796 enhances cytotoxicity triggered by bortezomib, heat shock protein (Hsp) 90 inhibitor, and dexamethasone via inhibition of p38 mitogen-activated protein kinase/Hsp27 pathway in multiple myeloma cell lines and inhibits paracrine tumour growth

Biologic sequelae of I{kappa}B kinase (IKK) inhibition in multiple myeloma: therapeutic implications

Blockade of XBP1 splicing by inhibition of IRE1α is a promising therapeutic option in multiple myeloma

Bortezomib induces canonical nuclear factor-kappaB activation in multiple myeloma cells

Bortezomib plus dexamethasone treatment followed by reduced-intensity allogeneic stem cell transplantation for multiple myeloma refractory to high-dose chemotherapy with autologous transplantation

Cardiac Light Chain Deposition Disease Mimicking Immunoglobulin Light Chain Amyloidosis: Two Branches of the Same Tree

Coadministration of tenofovir decreased atazanavir plasma concentration after unilateral nephrectomy ⬇️

Correction: Genomic vulnerability to LINE-1 hypomethylation is a potential determinant of the clinicogenetic features of multiple myeloma

DOT1L inhibition blocks multiple myeloma cell proliferation by suppressing IRF4-MYC signaling

Decrease of B-type natriuretic peptide to less than 200 pg/mL predicts longer survival in cardiac immunoglobulin light chain amyloidosis

Dual inhibition of akt/mammalian target of rapamycin pathway by nanoparticle albumin-bound-rapamycin and perifosine induces antitumor activity in multiple myeloma.

EPO-R+ myelodysplastic cells with ring sideroblasts produce high erythroferrone levels to reduce hepcidin expression in hepatic cells

Effective combination therapy of bortezomib and dexamethasone for two patients with refractory multiple myeloma

Elevation of Plasmin-α2-plasmin Inhibitor Complex Predicts the Diagnosis of Systemic AL Amyloidosis in Patients with Monoclonal Protein

Exceptionally rapid response to pembrolizumab in a SMARCA4-deficient thoracic sarcoma overexpressing PD-L1: A case report

Fatty acid synthase is a novel therapeutic target in multiple myeloma

Genomic vulnerability to LINE-1 hypomethylation is a potential determinant of the clinicogenetic features of multiple myeloma.

High dose of Zoledronic acid inhibits both osteoclasts and osteoblasts in an In Vivo mouse model

High-dose zoledronic acid impacts bone remodeling with effects on osteoblastic lineage and bone mechanical properties

IKKβ inhibitor in combination with bortezomib induces cytotoxicity in breast cancer cells

Inhibition of Akt induces significant downregulation of survivin and cytotoxicity in human multiple myeloma cells

Long-term prognosis of patients with HHV-6 reactivation following allogeneic HSCT.

MLN3897, a novel CCR1 inhibitor, impairs osteoclastogenesis and inhibits the interaction of multiple myeloma cells and osteoclasts.

Model of translational cancer research in multiple myeloma ⬇️

Molecular diagnostics of a single drug-resistant multiple myeloma case using targeted next-generation sequencing.

Nifuroxazide inhibits survival of multiple myeloma cells by directly inhibiting STAT3.

Occurrence of the African subgroup (Ia) of BK polyomavirus in younger Japanese children

Other Iatrogenic Immunodeficiency-associated Lymphoproliferative Disorder Presenting as Primary Bone Lymphoma in a Patient with Rheumatoid Arthritis.

PI3K/p110{delta} is a novel therapeutic target in multiple myeloma

Plasma tenofovir trough concentrations are associated with renal dysfunction in Japanese patients with HIV infection: a retrospective cohort study

Pneumothorax as an Adverse Event in Patients with Lung Metastasis of Soft Tissue Sarcoma under Eribulin Treatment

Possible clinical outcomes using early enteral nutrition in individuals with allogeneic hematopoietic stem cell transplantation: A single-center retrospective study

Quantification of BK polyoma viruria in Japanese children and adults with hemorrhagic cystitis complicating stem cell transplantation

Quantification of adenovirus species B and C viremia by real-time PCR in adults and children undergoing stem cell transplantation.

SNX-2112, a selective Hsp90 inhibitor, potently inhibits tumor cell growth, angiogenesis, and osteoclastogenesis in multiple myeloma and other hematologic tumors by abrogating signaling via Akt and ERK

Severe adverse events by tyrosine kinase inhibitors decrease survival rates in patients with newly diagnosed chronic phase chronic myeloid leukemia.

Small molecule CP-31398 induces reactive oxygen species-dependent apoptosis in human multiple myeloma

Sustained complete molecular remission after cessation of imatinib mesylate treatment in a patient with relapsed chronic myelogenous leukemia after allogeneic stem cell transplantation

The monoclonal antibody nBT062 conjugated to cytotoxic Maytansinoids has selective cytotoxicity against CD138-positive multiple myeloma cells in vitro and in vivo

The role of T-fimbrin in the response to DNA damage: silencing of T-fimbrin by small interfering RNA sensitizes human liver cancer cells to DNA-damaging agents

Usefulness of serum free light-chain assay for evaluation of therapeutic efficacy in non-secretory multiple myeloma

[Diffuse large B cell lymphoma with HIV infection presented with disseminated thromboembolism during antiretroviral therapy]

[Long-term survival after autologous peripheral blood stem cell transplantation in a patient with primary AL amyloidosis complicating congestive heart failure]

[Successful treatment with thalidomide-combined therapy in an amyloidosis-complicated multiple myeloma patient refractory to bortezomib, lenalidomide, and pomalidomide]

[Treatment of POEMS syndrome with lenalidomide and dexamethasone]

miR-7977 inhibits the Hippo-YAP signaling pathway in bone marrow mesenchymal stromal cells