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List of works by Rena Pawlick

A novel redox-active metalloporphyrin reduces reactive oxygen species and inflammatory markers but does not improve marginal mass engraftment in a murine donation after circulatory death islet transplantation model

scientific article published on 24 May 2016

A prevascularized subcutaneous device-less site for islet and cellular transplantation.

scientific article

AEB071 (sotrastaurin) does not exhibit toxic effects on human islets in vitro, nor after transplantation into immunodeficient mice.

scientific article published in November 2011

Antiaging Glycopeptide Protects Human Islets Against Tacrolimus-Related Injury and Facilitates Engraftment in Mice.

scientific article published on 18 November 2015

BMX-001, a novel redox-active metalloporphyrin, improves islet function and engraftment in a murine transplant model.

scientific article published on 21 February 2018

Bioengineered human pseudoislets form efficiently from donated tissue, compare favourably with native islets in vitro and restore normoglycaemia in mice

scientific article published on 03 July 2018

Bioengineered stem cells as an alternative for islet cell transplantation

scientific article

Caspase inhibitor IDN6556 facilitates marginal mass islet engraftment in a porcine islet autotransplant model

scientific article published in July 2012

Caspase inhibitor therapy synergizes with costimulation blockade to promote indefinite islet allograft survival

scientific article

Clinical islet isolation outcomes with a highly purified neutral protease for pancreas dissociation

scientific article

Comparison of human islet isolation outcomes using a new mammalian tissue-free enzyme versus collagenase NB-1.

scientific article published on August 2010

Costimulation blockade of both inducible costimulator and CD40 ligand induces dominant tolerance to islet allografts and prevents spontaneous autoimmune diabetes in the NOD mouse

scientific article published on 01 January 2006

Detecting rejection after mouse Islet transplantation utilizing islet protein-stimulated ELISPOT

Diabetes Is Reversed in a Murine Model by Marginal Mass Syngeneic Islet Transplantation Using a Subcutaneous Cell Pouch Device

scientific article

Effect of different induction strategies on effector, regulatory and memory lymphocyte sub-populations in clinical islet transplantation.

scientific article published on 15 August 2008

Engraftment Site and Effectiveness of the Pan-Caspase Inhibitor F573 to Improve Engraftment in Mouse and Human Islet Transplantation in Mice

scientific article published on 9 January 2017

Ferroptosis-inducing agents compromise in vitro human islet viability and function.

scientific article

Glutathione ethyl ester supplementation during pancreatic islet isolation improves viability and transplant outcomes in a murine marginal islet mass model

scientific article

Harnessing the Foreign Body Reaction in Marginal Mass Device-less Subcutaneous Islet Transplantation in Mice

scientific article published on 29 April 2016

Histopaque provides optimal mouse islet purification kinetics: comparison study with Ficoll, iodixanol and dextran

scientific article published on 01 July 2011

Improved islet recovery and efficacy through co-culture and co-transplantation of islets with human adipose-derived mesenchymal stem cells

scientific article published in PLoS ONE

Liraglutide, a long-acting human glucagon-like peptide 1 analogue, improves human islet survival in culture

scientific article published on 12 October 2009

Long-term function and optimization of mouse and human islet transplantation in the subcutaneous device-less site

scientific article published on 7 November 2016

Low energy X-ray (grenz ray) treatment of purified islets prior to allotransplant markedly decreases passenger leukocyte populations

scientific article published on 10 July 2017

Lung-Derived Microscaffolds Facilitate Diabetes Reversal after Mouse and Human Intraperitoneal Islet Transplantation

scientific article

Multiple combination therapies involving blockade of ICOS/B7RP-1 costimulation facilitate long-term islet allograft survival.

scientific article published in April 2004

Nonsimultaneous administration of pancreas dissociation enzymes during islet isolation

scientific article

Pan-caspase inhibitor F573 mitigates liver ischemia reperfusion injury in a murine model

scientific article published on 26 November 2019

Photoacoustic imaging of angiogenesis in a subcutaneous islet transplant site in a murine model

scientific article published in June 2016

Porcine marginal mass islet autografts resist metabolic failure over time and are enhanced by early treatment with liraglutide.

scientific article published on 8 January 2009

Posttransplant Characterization of Long-term Functional hESC-Derived Pancreatic Endoderm Grafts

scientific article published on 19 November 2018

Progress in Translational Regulatory T Cell Therapies for Type 1 Diabetes and Islet Transplantation

scientific article published on 28 November 2020

Protein kinase C inhibitor, AEB-071, acts complementarily with cyclosporine to prevent islet rejection in rats

scientific article published in January 2009

Reparixin, a CXCR1/2 inhibitor in islet allotransplantation

scientific article published on 21 June 2016

Resveratrol fails to improve marginal mass engraftment of transplanted islets of Langerhans in mice

scientific article published on 01 September 2011

Robust tolerance to fully allogeneic islet transplants achieved by chimerism with minimal conditioning

scientific article published in August 2005

The caspase inhibitor IDN-6556 (PF3491390) improves marginal mass engraftment after islet transplantation in mice

scientific article published on 18 May 2011

The caspase selective inhibitor EP1013 augments human islet graft function and longevity in marginal mass islet transplantation in mice.

scientific article

The use of an approved biodegradable polymer scaffold as a solid support system for improvement of islet engraftment.

scientific article published in December 2008

Transplantation of Human Pancreatic Endoderm Cells Reverses Diabetes Post Transplantation in a Prevascularized Subcutaneous Site.

scientific article

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