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List of works by Takeshi Yasumoto

A rapid microplate fluorescence method to detect yessotoxins based on their capacity to activate phosphodiesterases

scientific article published in March 2004

Absolute configuration at C14 and C85 in prymnesin-2, a potent hemolytic and ichthyotoxic glycoside isolated from the red tide algaPrymnesium parvum

scholarly article by Akio Morohashi et al published 2001 in Chirality

Amphidinol, a polyhydroxy-polyene antifungal agent with an unprecedented structure, from a marine dinoflagellate, Amphidinium klebsii

scientific article published on 19 March 2005

Azaspiracid-1, a potent, nonapoptotic new phycotoxin with several cell targets.

scientific article

Azaspiracid-4 inhibits Ca2+ entry by stored operated channels in human T lymphocytes.

scientific article published on 20 April 2005

Brevetoxin B3, a new brevetoxin analog isolated from the greenshell mussel perna canaliculus involved in neurotoxic shellfish poisoning in new zealand

article

Brevetoxin B4 isolated from greenshell musselsPerna canaliculus, the major toxin involved in neurotoxic shellfish poisoning in New Zealand

article

Characterization of F-actin depolymerization as a major toxic event induced by pectenotoxin-6 in neuroblastoma cells

scientific article published in June 2002

Chemical, molecular, and eco-toxicological investigation of Ostreopsis sp. from Cyprus Island: structural insights into four new ovatoxins by LC-HRMS/MS.

scientific article published on 25 November 2015

Chronic effects in mice caused by oral administration of sublethal doses of azaspiracid, a new marine toxin isolated from mussels ⬇️

scientific article published on 01 February 2002

Cytotoxic and cytoskeletal effects of azaspiracid-1 on mammalian cell lines

scientific article

Effects of Azaspiracids 2 and 3 on intracellular cAMP, [Ca2+], and pH.

scientific article

Effects of a synthetic analog of polycavernoside A on human neuroblastoma cells.

scientific article published on January 2007

Feasibility of using a surface plasmon resonance-based biosensor to detect and quantify yessotoxin

scientific article published on 15 January 2008

Gambieric acids: unprecedented potent antifungal substances isolated from cultures of a marine dinoflagellate Gambierdiscus toxicus

scientific article published on 18 March 2005

Gambierol: a new toxic polyether compound isolated from the marine dinoflagellate Gambierdiscus toxicus

scientific article published on 18 March 2005

Gymnocin-A, a cytotoxic polyether from the notorious red tide dinoflagellate, Gymnodinium mikimotoi

scientific article published on 26 March 2003

Gymnocin-B with the largest contiguous polyether rings from the red tide dinoflagellate, Karenia (formerly Gymnodinium) mikimotoi

scientific article published on 7 April 2005

Gymnodimine, a new marine toxin of unprecedented structure isolated from New Zealand oysters and the dinoflagellate, Gymnodinium sp.

scientific article published on 25 July 2002

Identification of polycavernoside A as the causative agent of the fatal food poisoning resulting from ingestion of the red Alga Gracilaria edulis in the Philippines

scientific article published in September 2004

Impact of the pectenotoxin C-43 oxidation degree on its cytotoxic effect on rat hepatocytes

scientific article

Induction of actin cytoskeleton rearrangement by methyl okadaate--comparison with okadaic acid.

scientific article published on 19 January 2008

Inhibition of brevetoxin binding to the voltage-gated sodium channel by gambierol and gambieric acid-A.

scientific article published in March 2003

Investigation of toxin profile of Mediterranean and Atlantic strains of Ostreopsis cf. siamensis (Dinophyceae) by liquid chromatography–high resolution mass spectrometry

Kinetic analysis of the interaction between yessotoxin and analogues and immobilized phosphodiesterases using a resonant mirror optical biosensor

scientific article published in July 2005

Lactone ring of pectenotoxins: a key factor for their activity on cytoskeletal dynamics

scientific article

Mutual binding inhibition of tetrodotoxin and saxitoxin to their binding protein from the plasma of the puffer fish, Fugu pardalis

scientific article published in November 2002

New insights on cytological and metabolic features of Ostreopsis cf. ovata Fukuyo (Dinophyceae): a multidisciplinary approach

scientific article

New saxitoxin analogues from the freshwater filamentous cyanobacterium Lyngbya wollei

scientific article published on January 1, 1997

Ostreocin-D impact on globular actin of intact cells.

scientific article

Palytoxin analogs from the dinoflagellate Ostreopsis siamensis

scientific article published on 18 March 2005

Polycavernoside A: a novel glycosidic macrolide from the red alga Polycavernosa tsudai (Gracilaria edulis)

scientific article published on 19 March 2005

Production of functionally active palytoxin-like compounds by Mediterranean Ostreopsis cf. siamensis.

scientific article

Prymnesin-2: A Potent Ichthyotoxic and Hemolytic Glycoside Isolated from the Red Tide Alga Prymnesium parvum

article by Tomoji Igarashi et al published January 1996 in Journal of the American Chemical Society

Quantification of yessotoxin using the fluorescence polarization technique and study of the adequate extraction procedure

scientific article published in September 2005

Relative configuration of yessotoxin and isolation of two new analogs from toxic scallops

scientific article published on 26 July 2002

Resonant mirror biosensor detection method based on yessotoxin-phosphodiesterase interactions.

scientific article published in December 2004

Structures and Partial Stereochemical Assignments for Prymnesin-1 and Prymnesin-2: Potent Hemolytic and Ichthyotoxic Glycosides Isolated from the Red Tide Alga Prymnesium parvum

scientific article published on 26 July 2002

Structures of New Pectenotoxin Analogs, Pectenotoxin-2 Seco Acid and 7-epi-Pectenotoxin-2 Seco Acid, Isolated from a Dinoflagellate and Greenshell Mussels

scientific article

Structure−Activity Relationships of Yessotoxins in Cultured Cells

scientific article published on 01 September 2004

Study of the interaction between different phosphodiesterases and yessotoxin using a resonant mirror biosensor

scientific article published in June 2006

Synthesis of the CDE/FG ring models of prymnesins: reassignment of the relative configuration of the E/F ring juncture

scientific article published in April 2004

Teratogenic effects of azaspiracid-1 identified by microinjection of Japanese medaka (Oryzias latipes) embryos

scientific article

The Absolute Configuration of Gambieric Acids A–D, Potent Antifungal Polyethers, Isolated from the Marine Dinoflagellate Gambierdiscus toxicus

scientific article published on 25 July 2002

The cytoskeleton, a structure that is susceptible to the toxic mechanism activated by palytoxins in human excitable cells.

scientific article

The methyl ester of okadaic acid is more potent than okadaic acid in disrupting the actin cytoskeleton and metabolism of primary cultured hepatocytes

scientific article

The sodium channel of human excitable cells is a target for gambierol.

scientific article published on 20 June 2006

Yessotoxin, a novel phycotoxin, activates phosphodiesterase activity. Effect of yessotoxin on cAMP levels in human lymphocytes.

scientific article

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