List of works - Pierre Drapeau

A hybrid electrical/chemical circuit in the spinal cord generates a transient embryonic motor behavior.

scientific article

A novel hypomorphic Looptail allele at the planar cell polarity Vangl2 gene ⬇️

scientific article published on February 18, 2011

A simplified method for identifying early CRISPR-induced indels in zebrafish embryos using High Resolution Melting analysis

scientific article

Activation of embryonic red and white muscle fibers during fictive swimming in the developing zebrafish

scientific article published in March 2002

Als2 mRNA splicing variants detected in KO mice rescue severe motor dysfunction phenotype in Als2 knock-down zebrafish

scientific article published on 16 June 2008

Augmented quantal release of acetylcholine at the vertebrate neuromuscular junction following tdp-43 depletion

scientific article

Calcium Channel Agonists Protect against Neuromuscular Dysfunction in a Genetic Model of TDP-43 Mutation in ALS ⬇️

scientific article published on January 23, 2013

Conserved pharmacological rescue of hereditary spastic paraplegia-related phenotypes across model organisms

scientific article published on 6 January 2016

Corrigendum: The Dietary Flavonoid, Luteolin, Negatively Affects Neuronal Differentiation.

scientific article

De novo STXBP1 mutations in mental retardation and nonsyndromic epilepsy

scientific article published in June 2009

De novo mutations in FOXP1 in cases with intellectual disability, autism, and language impairment

scientific article

De novo mutations in the gene encoding the synaptic scaffolding protein SHANK3 in patients ascertained for schizophrenia

scientific article

De novo truncating mutation in Kinesin 17 associated with schizophrenia

scientific article published on 19 June 2010

Development of the locomotor network in zebrafish

scientific article

Direct measure of the de novo mutation rate in autism and schizophrenia cohorts

scientific article

Disruption of AP1S1, causing a novel neurocutaneous syndrome, perturbs development of the skin and spinal cord

scientific article published in December 2008

Disruption of CLPB is associated with congenital microcephaly, severe encephalopathy and 3-methylglutaconic aciduria

scientific article

Excess of de novo deleterious mutations in genes associated with glutamatergic systems in nonsyndromic intellectual disability

scientific journal article

Expression of C9orf72-related dipeptides impairs motor function in a vertebrate model.

scientific article published on 8 March 2018

FUS and TARDBP but not SOD1 interact in genetic models of amyotrophic lateral sclerosis

scientific article

Fishing for causes and cures of motor neuron disorders

scientific article published on July 2014

Functional variants of POC5 identified in patients with idiopathic scoliosis

scientific article

Gain and loss of function of ALS-related mutations of TARDBP (TDP-43) cause motor deficits in vivo

scientific article

Glycine Promotes the Survival of a Subpopulation of Neural Stem Cells

scientific article published on 11 July 2018

Glycine Regulates Neural Stem Cell Proliferation During Development Lnx1-Dependent Notch Signaling

article published in 2019

Glycine decarboxylase deficiency-induced motor dysfunction in zebrafish is rescued by counterbalancing glycine synaptic level

scientific article published on 02 November 2018

Glycine receptors regulate interneuron differentiation during spinal network development

scholarly article

Homology Directed Knockin of Point Mutations in the Zebrafish tardbp and fus Genes in ALS Using the CRISPR/Cas9 System

scientific article

IRSSD 2014 Meeting Abstracts

Identification and characterization of novel rare mutations in the planar cell polarity gene PRICKLE1 in human neural tube defects

scientific article

In the swim of things: recent insights to neurogenetic disorders from zebrafish

scientific article published on 25 June 2010

Individual knock out of glycine receptor alpha subunits identifies a specific requirement of glra1 for motor function in zebrafish

scientific article published on 02 May 2019

Interaction between hindbrain and spinal networks during the development of locomotion in zebrafish

scientific article

Interpericyte tunnelling nanotubes regulate neurovascular coupling

scientific article published on 12 August 2020

Investigating the contribution of VAPB/ALS8 loss of function in amyotrophic lateral sclerosis

scientific article published on 26 February 2013

Itch is required for lateral line development in zebrafish

scientific article

Loss and gain of FUS function impair neuromuscular synaptic transmission in a genetic model of ALS.

scientific article published on 13 June 2013

Membrane properties related to the firing behavior of zebrafish motoneurons

scientific article

Methylene blue protects against TDP-43 and FUS neuronal toxicity in C. elegans and D. rerio

scientific article (publication date: 2012)

Mutant TDP-43 and FUS cause age-dependent paralysis and neurodegeneration in C. elegans

scientific article

Mutations in CAPN1 Cause Autosomal-Recessive Hereditary Spastic Paraplegia

scientific article published on May 2016

Mutations in CAPN1 Cause Autosomal-Recessive Hereditary Spastic Paraplegia

scientific article published on June 2016

Mutations in SYNGAP1 in autosomal nonsyndromic mental retardation

scientific article

Mutations in VANGL1 associated with neural-tube defects

scientific article

Mutations in the KIAA0196 gene at the SPG8 locus cause hereditary spastic paraplegia

scientific article

Mutations in the calcium-related gene IL1RAPL1 are associated with autism

scientific article published on 18 September 2008

Neurogenic role of the depolarizing chloride gradient revealed by global overexpression of KCC2 from the onset of development.

scientific article

Neuroleptics as therapeutic compounds stabilizing neuromuscular transmission in amyotrophic lateral sclerosis.

scientific article

Neuromuscular junction abnormalities in a zebrafish loss-of-function model of TDP-43

scientific article published on 21 November 2018

Neuronal labeling patterns in the spinal cord of adult transgenic Zebrafish

scientific article published on 26 September 2015

No association between SRGAP3/MEGAP haploinsufficiency and mental retardation.

scientific article published in May 2009

Non-canonical mTOR-Independent Role of DEPDC5 in Regulating GABAergic Network Development

article

Novel de novo SHANK3 mutation in autistic patients

scientific article

Pharmacological reduction of ER stress protects against TDP-43 neuronal toxicity in vivo.

scientific article published on 5 April 2013

RNA-Sequencing Reveals Unique Transcriptional Signatures of Running and Running-Independent Environmental Enrichment in the Adult Mouse Dentate Gyrus.

scientific article published on 13 April 2018

Regulation of spinal interneuron differentiation by the paracrine action of glycine ⬇️

scientific article published on February 1, 2012

Restrictions on the Importation of Zebrafish into Canada Associated with Spring Viremia of Carp Virus

scientific article published on June 2016

Rhythmic motor activity evoked by NMDA in the spinal zebrafish larva

scientific article

Role of Chd7 in Zebrafish: A Model for CHARGE Syndrome ⬇️

scientific article published on February 20, 2012

Role of the planar cell polarity gene Protein tyrosine kinase 7 in neural tube defects in humans

scientific article published on 14 September 2015

Sensory gating of an embryonic zebrafish interneuron during spontaneous motor behaviors

scientific article

Serotonin patterns locomotor network activity in the developing zebrafish by modulating quiescent periods ⬇️

scientific article published on December 1, 2003

Serotoninergic modulation of chloride homeostasis during maturation of the locomotor network in zebrafish.

scientific article

Simple animal models for amyotrophic lateral sclerosis drug discovery

scientific article published on June 2016

Single and Synergistic Effects of Cannabidiol and Δ-9-Tetrahydrocannabinol on Zebrafish Models of Neuro-Hyperactivity

Spontaneous glycine-induced calcium transients in spinal cord progenitors promote neurogenesis

scientific article published on 17 October 2012

Steps during the development of the zebrafish locomotor network

scientific article published on January 2003

Synaptic scaling and the development of a motor network

scientific article published in June 2010

The Dietary Flavonoid, Luteolin, Negatively Affects Neuronal Differentiation

The Novel Small Molecule TRVA242 Stabilizes Neuromuscular Junction Defects in Multiple Animal Models of Amyotrophic Lateral Sclerosis

scientific article published on 01 October 2019

The larvicide pyriproxyfen blamed during the Zika virus outbreak does not cause microcephaly in zebrafish embryos

scientific article

The vesicular integral protein-like gene is essential for development of a mechanosensory system in zebrafish

scientific article published in October 2008

Transcriptomic Analysis of Purified Embryonic Neural Stem Cells from Zebrafish Embryos Reveals Signaling Pathways Involved in Glycine-Dependent Neurogenesis

scientific article published on 31 March 2016

Transcriptomic Analysis of Zebrafish TDP-43 Transgenic Lines

Truncating mutations in NRXN2 and NRXN1 in autism spectrum disorders and schizophrenia

scientific article

VANGL1 rare variants associated with neural tube defects affect convergent extension in zebrafish.

scientific article published on 4 January 2010

WNK1/HSN2 mutation in human peripheral neuropathy deregulates KCC2 expression and posterior lateral line development in zebrafish (Danio rerio)

scientific article

Whole-cell patch-clamp recordings from identified spinal neurons in the zebrafish embryo

scientific article

Zebrafish Make It to Hollywood! ⬇️

scientific article published on September 1, 2012

Zebrafish models for the functional genomics of neurogenetic disorders ⬇️

scientific article published on September 29, 2010

γ-Aminobutyric acid receptor alpha 1 subunit loss of function causes genetic generalized epilepsy by impairing inhibitory network neurodevelopment

scientific article published on 15 October 2018

List of works by Pierre Drapeau

A hybrid electrical/chemical circuit in the spinal cord generates a transient embryonic motor behavior.

A novel hypomorphic Looptail allele at the planar cell polarity Vangl2 gene ⬇️

A simplified method for identifying early CRISPR-induced indels in zebrafish embryos using High Resolution Melting analysis

Activation of embryonic red and white muscle fibers during fictive swimming in the developing zebrafish

Als2 mRNA splicing variants detected in KO mice rescue severe motor dysfunction phenotype in Als2 knock-down zebrafish

Augmented quantal release of acetylcholine at the vertebrate neuromuscular junction following tdp-43 depletion

Calcium Channel Agonists Protect against Neuromuscular Dysfunction in a Genetic Model of TDP-43 Mutation in ALS ⬇️

Conserved pharmacological rescue of hereditary spastic paraplegia-related phenotypes across model organisms

Corrigendum: The Dietary Flavonoid, Luteolin, Negatively Affects Neuronal Differentiation.

De novo STXBP1 mutations in mental retardation and nonsyndromic epilepsy

De novo mutations in FOXP1 in cases with intellectual disability, autism, and language impairment

De novo mutations in the gene encoding the synaptic scaffolding protein SHANK3 in patients ascertained for schizophrenia

De novo truncating mutation in Kinesin 17 associated with schizophrenia

Development of the locomotor network in zebrafish

Direct measure of the de novo mutation rate in autism and schizophrenia cohorts

Disruption of AP1S1, causing a novel neurocutaneous syndrome, perturbs development of the skin and spinal cord

Disruption of CLPB is associated with congenital microcephaly, severe encephalopathy and 3-methylglutaconic aciduria

Excess of de novo deleterious mutations in genes associated with glutamatergic systems in nonsyndromic intellectual disability

Expression of C9orf72-related dipeptides impairs motor function in a vertebrate model.

FUS and TARDBP but not SOD1 interact in genetic models of amyotrophic lateral sclerosis

Fishing for causes and cures of motor neuron disorders

Functional variants of POC5 identified in patients with idiopathic scoliosis

Gain and loss of function of ALS-related mutations of TARDBP (TDP-43) cause motor deficits in vivo

Glycine Promotes the Survival of a Subpopulation of Neural Stem Cells

Glycine Regulates Neural Stem Cell Proliferation During Development Lnx1-Dependent Notch Signaling

Glycine decarboxylase deficiency-induced motor dysfunction in zebrafish is rescued by counterbalancing glycine synaptic level

Glycine receptors regulate interneuron differentiation during spinal network development

Homology Directed Knockin of Point Mutations in the Zebrafish tardbp and fus Genes in ALS Using the CRISPR/Cas9 System

IRSSD 2014 Meeting Abstracts

Identification and characterization of novel rare mutations in the planar cell polarity gene PRICKLE1 in human neural tube defects

In the swim of things: recent insights to neurogenetic disorders from zebrafish

Individual knock out of glycine receptor alpha subunits identifies a specific requirement of glra1 for motor function in zebrafish

Interaction between hindbrain and spinal networks during the development of locomotion in zebrafish

Interpericyte tunnelling nanotubes regulate neurovascular coupling

Investigating the contribution of VAPB/ALS8 loss of function in amyotrophic lateral sclerosis

Itch is required for lateral line development in zebrafish

Loss and gain of FUS function impair neuromuscular synaptic transmission in a genetic model of ALS.

Membrane properties related to the firing behavior of zebrafish motoneurons

Methylene blue protects against TDP-43 and FUS neuronal toxicity in C. elegans and D. rerio

Mutant TDP-43 and FUS cause age-dependent paralysis and neurodegeneration in C. elegans

Mutations in CAPN1 Cause Autosomal-Recessive Hereditary Spastic Paraplegia

Mutations in CAPN1 Cause Autosomal-Recessive Hereditary Spastic Paraplegia

Mutations in SYNGAP1 in autosomal nonsyndromic mental retardation

Mutations in VANGL1 associated with neural-tube defects

Mutations in the KIAA0196 gene at the SPG8 locus cause hereditary spastic paraplegia

Mutations in the calcium-related gene IL1RAPL1 are associated with autism

Neurogenic role of the depolarizing chloride gradient revealed by global overexpression of KCC2 from the onset of development.

Neuroleptics as therapeutic compounds stabilizing neuromuscular transmission in amyotrophic lateral sclerosis.

Neuromuscular junction abnormalities in a zebrafish loss-of-function model of TDP-43

Neuronal labeling patterns in the spinal cord of adult transgenic Zebrafish

No association between SRGAP3/MEGAP haploinsufficiency and mental retardation.

Non-canonical mTOR-Independent Role of DEPDC5 in Regulating GABAergic Network Development

Novel de novo SHANK3 mutation in autistic patients

Pharmacological reduction of ER stress protects against TDP-43 neuronal toxicity in vivo.

RNA-Sequencing Reveals Unique Transcriptional Signatures of Running and Running-Independent Environmental Enrichment in the Adult Mouse Dentate Gyrus.

Regulation of spinal interneuron differentiation by the paracrine action of glycine ⬇️

Restrictions on the Importation of Zebrafish into Canada Associated with Spring Viremia of Carp Virus

Rhythmic motor activity evoked by NMDA in the spinal zebrafish larva

Role of Chd7 in Zebrafish: A Model for CHARGE Syndrome ⬇️

Role of the planar cell polarity gene Protein tyrosine kinase 7 in neural tube defects in humans

Sensory gating of an embryonic zebrafish interneuron during spontaneous motor behaviors

Serotonin patterns locomotor network activity in the developing zebrafish by modulating quiescent periods ⬇️

Serotoninergic modulation of chloride homeostasis during maturation of the locomotor network in zebrafish.

Simple animal models for amyotrophic lateral sclerosis drug discovery

Single and Synergistic Effects of Cannabidiol and Δ-9-Tetrahydrocannabinol on Zebrafish Models of Neuro-Hyperactivity

Spontaneous glycine-induced calcium transients in spinal cord progenitors promote neurogenesis

Steps during the development of the zebrafish locomotor network

Synaptic scaling and the development of a motor network

The Dietary Flavonoid, Luteolin, Negatively Affects Neuronal Differentiation

The Novel Small Molecule TRVA242 Stabilizes Neuromuscular Junction Defects in Multiple Animal Models of Amyotrophic Lateral Sclerosis

The larvicide pyriproxyfen blamed during the Zika virus outbreak does not cause microcephaly in zebrafish embryos

The vesicular integral protein-like gene is essential for development of a mechanosensory system in zebrafish

Transcriptomic Analysis of Purified Embryonic Neural Stem Cells from Zebrafish Embryos Reveals Signaling Pathways Involved in Glycine-Dependent Neurogenesis

Transcriptomic Analysis of Zebrafish TDP-43 Transgenic Lines

Truncating mutations in NRXN2 and NRXN1 in autism spectrum disorders and schizophrenia

VANGL1 rare variants associated with neural tube defects affect convergent extension in zebrafish.

WNK1/HSN2 mutation in human peripheral neuropathy deregulates KCC2 expression and posterior lateral line development in zebrafish (Danio rerio)

Whole-cell patch-clamp recordings from identified spinal neurons in the zebrafish embryo

Zebrafish Make It to Hollywood! ⬇️