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List of works by Erik J. Tokar

14. Metal Ions in Human Cancer Development

article

Aberrant cytokeratin expression during arsenic-induced acquired malignant phenotype in human HaCaT keratinocytes consistent with epidermal carcinogenesis

scientific article published on 12 June 2009

Aberrant microRNA expression likely controls RAS oncogene activation during malignant transformation of human prostate epithelial and stem cells by arsenic

scientific article published on 15 January 2014

Agglomerates of aberrant DNA methylation are associated with toxicant-induced malignant transformation

scientific article

Arsenic Alters Exosome Quantity and Cargo to Mediate Stem Cell Recruitment Into a Cancer Stem Cell-Like Phenotype

scientific article published on 01 September 2018

Arsenic and Environmental Health: State of the Science and Future Research Opportunities

scientific article

Arsenic exposure in utero and nonepidermal proliferative response in adulthood in Tg.AC mice

scientific article published in May 2010

Arsenic exposure in utero exacerbates skin cancer response in adulthood with contemporaneous distortion of tumor stem cell dynamics

scientific article

Arsenic exposure transforms human epithelial stem/progenitor cells into a cancer stem-like phenotype

scientific article

Arsenic, Stem Cells, and the Developmental Basis of Adult Cancer ⬇️

scientific article published on November 11, 2010

Arsenic-induced aberrant gene expression in fetal mouse primary liver-cell cultures

scientific article published on October 2008

Arsenic-induced cancer cell phenotype in human breast epithelia is estrogen receptor-independent but involves aromatase activation

scientific article published on 26 September 2013

Arsenic-specific stem cell selection during malignant transformation

scientific article

Arsenic-transformed malignant prostate epithelia can convert noncontiguous normal stem cells into an oncogenic phenotype

scientific article

Arsenite malignantly transforms human prostate epithelial cells in vitro by gene amplification of mutated KRAS

article

Cadmium Exposure and Ovarian Reserve in Women Ages 35-49 Years: The Impact on Results of Creatinine Adjustment Approach to Correct for Urinary Dilution

scientific article published on 03 April 2020

Cadmium Induces p53-Dependent Apoptosis in Human Prostate Epithelial Cells ⬇️

scientific article published on March 20, 2012

Cadmium malignantly transforms normal human breast epithelial cells into a basal-like phenotype

scientific article

Cancer in experimental animals exposed to arsenic and arsenic compounds ⬇️

scientific article published on November 1, 2010

Carcinogenic Effects of “Whole-Life” Exposure to Inorganic Arsenic in CD1 Mice ⬇️

scientific article published on October 11, 2010

Chemoprevention of prostate cancer by cholecalciferol (vitamin D3): 25-hydroxylase (CYP27A1) in human prostate epithelial cells

scientific article published on January 2005

Cholecalciferol (vitamin D3) and the retinoid N-(4-hydroxyphenyl)retinamide (4-HPR) are synergistic for chemoprevention of prostate cancer.

scientific article published on January 2006

Cholecalciferol (vitamin D3) inhibits growth and invasion by up-regulating nuclear receptors and 25-hydroxylase (CYP27A1) in human prostate cancer cells

scientific article published on January 2005

Chronic administration of 2-acetylaminofluorene alters the cellular iron metabolism in rat liver

scientific article

Chronic cadmium exposure in vitro causes acquisition of multiple tumor cell characteristics in human pancreatic epithelial cells.

scientific article

Chronic cadmium exposure in vitro induces cancer cell characteristics in human lung cells.

scientific article published on 26 June 2013

Chronic exposure of renal stem cells to inorganic arsenic induces a cancer phenotype

scientific article

Chronic inorganic arsenic exposure in vitro induces a cancer cell phenotype in human peripheral lung epithelial cells

scientific article

Coordinate H3K9 and DNA methylation silencing of ZNFs in toxicant-induced malignant transformation

scientific article published on 06 August 2013

Depot Medroxyprogesterone Acetate Use and Blood Lead Levels in a Cohort of Young Women

scientific article published on 18 November 2020

Differential DNA methylation profile of key genes in malignant prostate epithelial cells transformed by inorganic arsenic or cadmium

scientific article published on 25 April 2015

Early life inorganic lead exposure induces testicular teratoma and renal and urinary bladder preneoplasia in adult metallothionein-knockout mice but not in wild type mice

scientific article published on 23 June 2010

Elucidation of Mechanisms of Topotecan-Induced Cell Death in Human Breast MCF-7 Cancer Cells by Gene Expression Analysis

scientific article published on 17 July 2020

Fetal arsenic exposure appears to facilitate endocrine disruption by postnatal diethylstilbestrol in neonatal mouse adrenal

scientific article published on 7 August 2009

Fluorescent proteins such as eGFP lead to catalytic oxidative stress in cells

scientific article published on 10 March 2017

Gene expression profiling for nitric oxide prodrug JS-K to kill HL-60 myeloid leukemia cells

scientific article

Haploinsufficiency of SIRT1 Enhances Glutamine Metabolism and Promotes Cancer Development

scientific article published on 31 January 2017

Intercellular communication and human prostate carcinogenesis

scientific article

KRAS-retroviral fusion transcripts and gene amplification in arsenic-transformed, human prostate CAsE-PE cancer cells

scientific article published on 25 April 2020

Leptin is key to peroxynitrite-mediated oxidative stress and Kupffer cell activation in experimental non-alcoholic steatohepatitis

scientific article published on December 2012

Lung tumors in mice induced by "whole-life" inorganic arsenic exposure at human-relevant doses

scientific article

Mechanisms Underlying Latent Disease Risk Associated with Early-Life Arsenic Exposure: Current Research Trends and Scientific Gaps.

scientific article published on 26 June 2015

Metal ions in human cancer development

scientific article published on January 1, 2011

Methylarsonous acid causes oxidative DNA damage in cells independent of the ability to biomethylate inorganic arsenic

scientific article

MicroRNAs: small molecules with big effects.

scientific article published in December 2016

Mitigation of arsenic-induced acquired cancer phenotype in prostate cancer stem cells by miR-143 restoration

scientific article published on 22 December 2015

NTP Research Report on Absence of Formaldehyde-Induced Neoplasia in Trp53 Haploinsufficient Mice Exposed by Inhalation: Research Report 3

scientific article published on 18 July 2018

Nitric Oxide Down-Regulates Topoisomerase I and Induces Camptothecin Resistance in Human Breast MCF-7 Tumor Cells

scientific article

Nitric oxide inhibits topoisomerase II activity and induces resistance to topoisomerase II-poisons in human tumor cells

scientific article published on 16 April 2016

Opportunities and Challenges for Dietary Arsenic Intervention

scientific article published on 01 August 2018

Overabundance of Putative Cancer Stem Cells in Human Skin Keratinocyte Cells Malignantly Transformed by Arsenic ⬇️

scientific article published on October 19, 2011

Oxidative DNA damage after acute exposure to arsenite and monomethylarsonous acid in biomethylation-deficient human cells

scientific article published on 6 February 2013

Pluripotent Stem Cells in Developmental Toxicity Testing: A Review of Methodological Advances

scientific article published on 01 September 2018

Proinflammatory adipokine leptin mediates disinfection byproduct bromodichloromethane-induced early steatohepatitic injury in obesity

scientific article published on 22 February 2013

Recruitment of normal stem cells to an oncogenic phenotype by noncontiguous carcinogen-transformed epithelia depends on the transforming carcinogen.

scientific article published on 17 May 2013

Regulatory role of KEAP1 and NRF2 in PPARγ expression and chemoresistance in human non-small-cell lung carcinoma cells

scientific article

Renal, hepatic, pulmonary and adrenal tumors induced by prenatal inorganic arsenic followed by dimethylarsinic acid in adulthood in CD1 mice

scientific article

Requirement of arsenic biomethylation for oxidative DNA damage

scientific article published on December 2009

Response to letter to the editor by Cohen et al. (2014) "Re: Waalkes et al.: Lung tumors in mice induced by "whole-life" inorganic arsenic exposure at human-relevant doses, Arch Toxicol, 2014".

scientific article published on 25 September 2014

Selection of cell lines with enhanced invasive phenotype from xenografts of the human prostate cancer cell line WPE1-NB26.

scientific article published on January 2005

Silencing KRAS Overexpression in Cadmium-Transformed Prostate Epithelial Cells Mitigates Malignant Phenotype

scientific article published on 11 August 2016

Silencing KRAS overexpression in arsenic-transformed prostate epithelial and stem cells partially mitigates malignant phenotype

scientific article

Stem/progenitor and intermediate cell types and the origin of human prostate cancer

scientific article published on December 2005

Tumors and proliferative lesions in adult offspring after maternal exposure to methylarsonous acid during gestation in CD1 mice ⬇️

scientific article published on March 8, 2012

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