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List of works by Rebecca Roberts

6-thioguanine nucleotides and thiopurine methyltransferase activity: important factors determining response to treatment and incidence of adverse effects from azathioprine and 6-MP.

scientific article published in July 2003

A human leukocyte antigen locus haplotype confers risk for allopurinol-related adverse effects in Caucasian patients with gout

scientific article published in August 2015

A multiplexed allele-specific polymerase chain reaction assay for the detection of common thiopurine S-methyltransferase (TPMT) mutations

scientific article published in March 2004

ABCG2 rs2231142 (Q141K) and oxypurinol concentrations in people with gout receiving allopurinol

scientific article published on 18 September 2018

Adenosine receptor expression in rheumatoid synovium: a basis for methotrexate action

scientific article

Allele frequency differences of cytochrome P450 polymorphisms in a sample of New Zealand Māori.

scientific article published on 18 April 2008

Allopurinol-thiopurine combination therapy in inflammatory bowel disease: are there genetic clues to this puzzle?

scientific article published on November 2010

An envirogenomic signature is associated with risk of IBD-related surgery in a population-based Crohn's disease cohort

scientific article published on 2 July 2013

Association between ABCG2 rs2231142 and poor response to allopurinol: replication and meta-analysis

scientific article published on 12 January 2018

Association between cytochrome P450 2D6 genotype and harm avoidance

scientific article published in May 2004

Association of Crohn's disease-related chromosome 1q32 with ankylosing spondylitis is independent of bowel symptoms and faecal calprotectin

scientific article

Association of FcgR2a, but not FcgR3a, with inflammatory bowel diseases across three Caucasian populations†

scientific article published on 1 December 2010

Association of higher DEFB4 genomic copy number with Crohn's disease

scientific article published on 6 October 2009

Association of the HLA locus and TNF with type I autoimmune hepatitis susceptibility in New Zealand Caucasians

scientific article published on 30 July 2013

Association of the protein-tyrosine phosphatase nonreceptor type substrate 1 (PTPNS1) gene with inflammatory bowel disease

scientific article

Beyond TPMT: genetic influences on thiopurine drug responses in inflammatory bowel disease

article

Caspase Recruitment Domain-Containing Protein 15 Mutations in Patients with Colorectal Cancer

scientific article published on 01 March 2006

Comment: Breast-feeding during maternal use of azathioprine

scientific article published on 27 March 2007

Consolidation of Evidence for Association of the KIAA1109-TENR-IL2-IL21 rs6822844 Variant With Crohn's Disease

scientific article published in May 2010

Correlation between trough plasma dabigatran concentrations and estimates of glomerular filtration rate based on creatinine and cystatin C

scientific article

Correlation of CYP2D6 genotype with perhexiline phenotypic metabolizer status

scientific article published in October 2003

Current relevance of pharmacogenetics in immunomodulation treatment for Crohn's disease

scientific article published on October 2012

Cytochrome P450 2D6 genotype does not predict SSRI (fluoxetine or paroxetine) induced hyponatraemia

scientific article published in June 2002

Differential association of two PTPN22 coding variants with Crohn's disease and ulcerative colitis

scientific article published in February 2011

Effect of Genetic Polymorphisms in the Folate Pathway on Methotrexate Therapy in Rheumatic Diseases ⬇️

scientific article published on October 1, 2011

Effect of inflammatory bowel disease classification changes on NOD2 genotype–phenotype associations in a population-based cohort

scientific article published on 01 October 2007

Erratum: Corrigendum: Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

scholarly article published in Nature Genetics

Exposure to thiopurine drugs through breast milk is low based on metabolite concentrations in mother-infant pairs

scientific article

Frequency of CYP2C9 polymorphisms in Polynesian people and potential relevance to management of gout with benzbromarone

scientific article published on 7 August 2013

Genetic susceptibility in IBD: overlap between ulcerative colitis and Crohn's disease

scientific article published in February 2013

Genome-wide association study identifies distinct genetic contributions to prognosis and susceptibility in Crohn's disease.

scientific article published on 9 January 2017

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

scientific article

How the pharmacogenetics of cytochrome P450 enzymes may affect prescribing

scientific article

Human SNP links differential outcomes in inflammatory and infectious disease to a FOXO3-regulated pathway

scientific article published on 12 September 2013

IL23R R381Q and ATG16L1 T300A Are Strongly Associated With Crohn's Disease in a Study of New Zealand Caucasians With Inflammatory Bowel Disease

article

Identification of a novel thiopurine S-methyltransferase allele (TPMT*37)

scientific article published in June 2014

Impaired response or insufficient dosage? Examining the potential causes of "inadequate response" to allopurinol in the treatment of gout

scientific article

Incidence of Mycobacterium avium subspecies paratuberculosis in a population-based cohort of patients with Crohn's disease and control subjects.

scientific article

Independent replication of an association of CNVR7113.6 with Crohn's disease in Caucasians.

scientific article published on 10 May 2011

Influence of Genotype on Warfarin Maintenance Dose Predictions Produced Using a Bayesian Dose Individualization Tool.

scientific article published on December 2016

Interaction of the inflammasome genes CARD8 and NLRP3 in abdominal aortic aneurysms

scientific article published in September 2011

Interactions among genes influencing bacterial recognition increase IBD risk in a population-based New Zealand cohort

scientific article published on 9 March 2009

KCNN4 gene variant is associated with ileal Crohn's Disease in the Australian and New Zealand population

scientific article published on 20 April 2010

Lack of association between the ITPA 94C>A polymorphism and adverse effects from azathioprine

scientific article published in November 2004

Linking pharmacovigilance with pharmacogenetics

scientific article published in January 2004

Macrophage migration inhibitory factor gene polymorphisms in inflammatory bowel disease: an association study in New Zealand Caucasians and meta-analysis

scientific article published on October 2013

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

scientific journal article

Methods for Predicting Warfarin Dose Requirements.

scientific article published on August 2015

NOD2 and ATG16L1 polymorphisms affect monocyte responses in Crohn's disease

scientific article

No evidence of increased adverse drug reactions in cytochrome P450 CYP2D6 poor metabolizers treated with fluoxetine or nortriptyline

scientific article

Nonsynonymous Polymorphism in Guanine Monophosphate Synthetase Is a Risk Factor for Unfavorable Thiopurine Metabolite Ratios in Patients With Inflammatory Bowel Disease

scientific article published on 01 November 2018

PACSIN2 does not influence thiopurine-related toxicity in patients with inflammatory bowel disease

scientific article published on 01 June 2014

Perianal disease combined with NOD2 genotype predicts need for IBD-related surgery in Crohn's disease patients from a population-based cohort.

scientific article published on March 2013

Pharmacogenetic considerations in the treatment of gout

scientific article published on 16 April 2015

Polymorphisms within the folate pathway predict folate concentrations but are not associated with disease activity in rheumatoid arthritis patients on methotrexate

scientific article published in June 2010

Prevalence of HLA-B27 in the New Zealand population: effect of age and ethnicity

scientific article published on 22 October 2013

Rapid Detection of Common CARD15 Variants in Patients with Inflammatory Bowel Disease

Rapid detection of common CARD15 variants in patients with inflammatory bowel disease.

scientific article published in January 2004

Rapid detection of common cytochrome P450 2D6 alleles in Caucasians

scientific article published on 20 December 2005

S1169 KCNN4 Gene Variant Is Associated with Ileal Crohn's Disease

article

SLC11A1 polymorphisms in inflammatory bowel disease and Mycobacterium avium subspecies paratuberculosis status

scientific article published on December 2010

Smoking behaviour modifiesIL23r-associated disease risk in patients with Crohn's disease

The pharmacokinetics and pharmacogenetics of the antiemetic cyclizine in palliative care patients

scientific article published on 30 December 2011

The use of low dose methotrexate in rheumatoid arthritis - are we entering a new era of therapeutic drug monitoring and pharmacogenomics?

scientific article published on 20 October 2006

Trinucleotide repeat variants in the promoter of the thiopurine S-methyltransferase gene of patients exhibiting ultra-high enzyme activity

scientific article published in May 2008

Update on thiopurine pharmacogenetics in inflammatory bowel disease

scientific article published on 12 June 2015

Vitamin D receptor polymorphisms in colorectal cancer in New Zealand: an association study

scientific article published on 8 June 2012

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