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List of works by Andrew Wellman

A Novel Model to Estimate Key OSA Endotypes from Standard Polysomnography and Clinical Data and Their Contribution to OSA Severity

scientific article published on 16 October 2020

A method for measuring and modeling the physiological traits causing obstructive sleep apnea ⬇️

scientific article published on March 24, 2011

A scalable method of determining physiological endotypes of sleep apnea from a polysomnographic sleep study

scientific article published on 15 September 2020

A simplified method for determining phenotypic traits in patients with obstructive sleep apnea.

scientific article published on 24 January 2013

Acetazolamide attenuates the ventilatory response to arousal in patients with obstructive sleep apnea

scientific article published on February 2013

Acetazolamide improves loop gain but not the other physiological traits causing obstructive sleep apnoea.

scientific article published on 4 January 2012

Airflow Shape Is Associated With the Pharyngeal Structure Causing OSA.

scientific article published on 23 June 2017

Airway dilator muscle activity and lung volume during stable breathing in obstructive sleep apnea

scientific article published on March 2009

An Integrative Model of Physiological Traits Can be Used to Predict Obstructive Sleep Apnea and Response to Non Positive Airway Pressure Therapy.

scientific article published on June 2015

An Official American Thoracic Society Workshop Report: Noninvasive Identification of Inspiratory Flow Limitation in Sleep Studies

scientific article

Apnea-Hypopnea Event Duration Predicts Mortality in Men and Women in the Sleep Heart Health Study

scientific article published on 01 April 2019

Arousal Intensity is a Distinct Pathophysiological Trait in Obstructive Sleep Apnea

scientific article published on 20 October 2016

Breath-holding as a means to estimate the loop gain contribution to obstructive sleep apnoea

scientific article published on 06 July 2018

Chemical control stability in the elderly

scientific article published on 22 February 2007

Clinical predictors of the respiratory arousal threshold in patients with obstructive sleep apnea.

scientific article

Complex sleep apnea: it isn't really a disease.

scientific article published in October 2008

CrossTalk opposing view: The human upper airway during sleep does not behave like a Starling resistor ⬇️

scientific article published on May 1, 2013

Defining phenotypic causes of obstructive sleep apnea. Identification of novel therapeutic targets.

scientific article published on October 2013

Desipramine Increases Genioglossus Activity and Reduces Upper Airway Collapsibility during Non-REM Sleep in Healthy Subjects

scientific article published on 11 March 2016

Desipramine improves upper airway collapsibility and reduces OSA severity in patients with minimal muscle compensation

scientific article published on 6 October 2016

Discriminating the severity of pharyngeal collapsibility (Pcrit) using anthropometric and polysomnographic indices

scientific article published on 22 May 2020

Effect of 4-Aminopyridine on Genioglossus Muscle Activity during Sleep in Healthy Adults

scientific article

Effect of Sleeping Position on Upper Airway Patency in Obstructive Sleep Apnea Is Determined by the Pharyngeal Structure Causing Collapse

scientific article

Effect of oxygen in obstructive sleep apnea: role of loop gain.

scientific article

Effects of Tiagabine on Slow Wave Sleep and Arousal Threshold in Patients With Obstructive Sleep Apnea

scientific article

Effects of hyperoxia and hypoxia on the physiological traits responsible for obstructive sleep apnoea

scientific article

Effects of the Combination of Atomoxetine and Oxybutynin on OSA Endotypic Traits

scientific article published on 30 January 2020

Endotypic Mechanisms of Successful Hypoglossal Nerve Stimulation for Obstructive Sleep Apnea

scientific article published on 24 September 2020

Enhanced upper-airway muscle responsiveness is a distinct feature of overweight/obese individuals without sleep apnea

scientific article

Estimation of Pharyngeal Collapsibility During Sleep by Peak Inspiratory Airflow

scientific article

Eszopiclone increases the respiratory arousal threshold and lowers the apnoea/hypopnoea index in obstructive sleep apnoea patients with a low arousal threshold ⬇️

scientific article published on June 1, 2011

Expiratory resistance increases end-expiratory lung volume during sleep

scientific article published on April 2012

Flow identified site of collapse during drug-induced sleep endoscopy: feasibility and preliminary results

scientific article published on 14 September 2020

Genioglossal muscle response to CO2 stimulation during NREM sleep

scientific article

Hypoxic burden captures sleep apnoea-specific nocturnal hypoxaemia

scientific article published on 01 September 2019

Identifying obstructive sleep apnoea patients responsive to supplemental oxygen therapy

scientific article published on 27 September 2018

Influence of pharyngeal muscle activity on inspiratory negative effort dependence in the human upper airway.

scientific article

Influence of wakefulness on pharyngeal airway muscle activity

scientific article

Interhemispheric sleep depth coherence predicts driving safety in sleep apnea

scientific article published on 22 May 2020

Loop gain in REM versus non-REM sleep using CPAP manipulation: A pilot study

scientific article published on 18 June 2019

Mandibular Advancement Device Treatment Efficacy is Associated with Polysomnographic Endotypes

scientific article published on 18 September 2020

Mechanisms used to restore ventilation after partial upper airway collapse during sleep in humans

scientific article published on 5 April 2007

Mild Airflow Limitation during N2 Sleep Increases K-complex Frequency and Slows Electroencephalographic Activity.

scientific article published on 19 November 2015

Model-based characterization of ventilatory stability using spontaneous breathing.

scientific article

Model-based estimation of loop gain using spontaneous breathing: a validation study.

scientific article

NREM Apnea and Hypopnea Duration Varies Across Population Groups and Physiologic Traits

scientific article published on 07 December 2020

New insights into the timing and potential mechanisms of respiratory-induced cortical arousals in obstructive sleep apnea

scientific article published on 01 November 2018

Obstructive sleep apnea in older adults is a distinctly different physiological phenotype

scientific article

PSGs: more than just the AHI.

scientific article published on 15 June 2013

Palatal prolapse as a signature of expiratory flow limitation and inspiratory palatal collapse in patients with obstructive sleep apnoea.

scientific article published on 14 February 2018

Phenotyping Pharyngeal Pathophysiology Using Polysomnography in Patients with Obstructive Sleep Apnea

scientific article published on 12 January 2018

Physiological Traits and Adherence to Obstructive Sleep Apnea Treatment in Patients with Stroke

scientific article published on 21 February 2020

Polysomnographic Endotyping to Select Patients with Obstructive Sleep Apnea for Oral Appliances

scientific article published on 01 November 2019

Predicting epiglottic collapse in patients with obstructive sleep apnoea.

scientific article

Predicting sleep apnea responses to oral appliance therapy using polysomnographic airflow

scientific article published on 10 February 2020

Prevalence, Associated Clinical Features, and Impact on Continuous Positive Airway Pressure Use of a Low Respiratory Arousal Threshold Among Male United States Veterans With Obstructive Sleep Apnea

scientific article published on 15 May 2018

Prolonged Circulation Time is Associated with Mortality Among Older Men with Sleep Disordered Breathing

scientific article published on 15 October 2020

Quantifying the Arousal Threshold using Polysomnography in Obstructive Sleep Apnea

scientific article published on 9 November 2017

Quantifying the magnitude of pharyngeal obstruction during sleep using airflow shape

scientific article published on 04 July 2019

Quantifying the ventilatory control contribution to sleep apnoea using polysomnography

scientific article

Reboxetine and hyoscine butylbromide improve upper airway function during nonrapid eye movement and suppress rapid eye movement sleep in healthy individuals

scientific article published on 01 April 2019

Rebuttal from James P. Butler, Robert L. Owens, Atul Malhotra and Andrew Wellman ⬇️

scientific article published on May 1, 2013

Reply to Patel and Althouse: Robust Methods Are Needed to Evaluate the Pharmacologic Treatment of Obstructive Sleep Apnea

article by Luigi Taranto-Montemurro et al published 15 May 2019 in American Journal of Respiratory and Critical Care Medicine

Reply: Arousal threshold in obstructive sleep apnea

scientific article published on February 2014

Reply: Is the Muscle the Only Potential Target of Desipramine in Obstructive Sleep Apnea Syndrome?

scientific article

Resonance as the Mechanism of Daytime Periodic Breathing in Patients with Heart Failure.

scientific article

Respiratory control stability and upper airway collapsibility in men and women with obstructive sleep apnea

scientific article

Respiratory system loop gain in normal men and women measured with proportional-assist ventilation

scientific article published on 20 September 2002

Response to a combination of oxygen and a hypnotic as treatment for obstructive sleep apnoea is predicted by a patient's therapeutic CPAP requirement

scientific article published on 13 April 2017

Retropalatal and retroglossal airway compliance in patients with obstructive sleep apnea

scientific article published on 18 June 2018

Stable Breathing in Patients With Obstructive Sleep Apnea Is Associated With Increased Effort but Not Lowered Metabolic Rate.

scientific article

Structure and severity of pharyngeal obstruction determine oral appliance efficacy in sleep apnoea

scientific article published on 01 October 2019

Targeting Endotypic Traits with Medications for the Pharmacological Treatment of Obstructive Sleep Apnea. A Review of the Current Literature

scientific article published on 02 November 2019

Termination of Respiratory Events with and without Cortical Arousal in Obstructive Sleep Apnea ⬇️

scientific article published on August 11, 2011

Test of the Starling resistor model in the human upper airway during sleep

scientific article

The Combination of Atomoxetine and Oxybutynin Greatly Reduces Obstructive Sleep Apnea Severity: A Randomized, Placebo-Controlled, Double-Blind Crossover Trial

scientific article published on 01 May 2019

The Combination of Supplemental Oxygen and a Hypnotic Markedly Improves Obstructive Sleep Apnea in Patients with a Mild to Moderate Upper Airway Collapsibility.

scientific article published on 09 September 2016

The Effect of Body Position on Physiological Factors that Contribute to Obstructive Sleep Apnea.

scientific article

The chicken-or-egg debate in OSA pathogenesis.

scientific article published on October 2009

The classical Starling resistor model often does not predict inspiratory airflow patterns in the human upper airway

scientific article

The hypoxic burden of sleep apnoea predicts cardiovascular disease-related mortality: the Osteoporotic Fractures in Men Study and the Sleep Heart Health Study

article

The hypoxic burden: a novel sleep apnoea severity metric and a predictor of cardiovascular mortality-Reply to 'The hypoxic burden: also known as the desaturation severity parameter'

scientific article published on 01 September 2019

The influence of aging on pharyngeal collapsibility during sleep.

scientific article published on 5 April 2007

The pharyngeal airway: is bigger really better?

scientific article published in June 2012

The sleep apnea-specific hypoxic burden predicts incident heart failure

scientific article published on 13 April 2020

Therapeutic CPAP Level Predicts Upper Airway Collapsibility in Patients With Obstructive Sleep Apnea

scientific article published on 13 April 2017

Trazodone Effects on Obstructive Sleep Apnea and Non-REM Arousal Threshold.

scientific article published on May 2015

Trazodone increases the respiratory arousal threshold in patients with obstructive sleep apnea and a low arousal threshold

scientific article

Tube Law of the Pharyngeal Airway in Sleeping Patients with Obstructive Sleep Apnea

scientific article

Upper Airway Collapsibility (Pcrit) and Pharyngeal Dilator Muscle Activity are Sleep Stage Dependent

scientific article published on 19 November 2015

Upper airway collapsibility and patterns of flow limitation at constant end-expiratory lung volume

scientific article

Upper-Airway Collapsibility and Loop Gain Predict the Response to Oral Appliance Therapy in Patients with Obstructive Sleep Apnea.

scientific article published on 15 May 2016

Validating an Algorithm for Automatic Scoring of Inspiratory Flow Limitation Within a Range of Recording Settings

scientific article published on 01 July 2018

Ventilatory control and airway anatomy in obstructive sleep apnea

scientific article

When CPAP is stopped: what are the "on switches" of sleep apnoea?

scientific article

Which OSA Patients Might Respond to Nasal Valves? ⬇️

scientific article published on February 15, 2011

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