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List of works by Susanna Nikolaus

A case-only study of gene-environment interaction between genetic susceptibility variants in NOD2 and cigarette smoking in Crohn's disease aetiology.

scientific article

A comparison of oligonucleotide and cDNA-based microarray systems

scientific article published on 13 February 2004

A functional EXO1 promoter variant is associated with prolonged life expectancy in centenarians

scientific article published on 19 August 2009

A genome-wide association study confirms APOE as the major gene influencing survival in long-lived individuals

article

Abdominal malrotation overlooked at extensive cross-sectional imaging and leading to life-threatening gastrointestinal bleeding

scientific article published on 29 December 2015

Anti-TNF-α antibodies improve intestinal barrier function in Crohn's disease

article

Association between variants of PRDM1 and NDP52 and Crohn's disease, based on exome sequencing and functional studies

scientific article published on 25 April 2013

Association of FOXO3A variation with human longevity confirmed in German centenarians

scientific article

Association of NOD2 (CARD 15) genotype with clinical course of Crohn's disease: a cohort study

scientific article

Combination therapy with vedolizumab and etanercept in a patient with pouchitis and spondylarthritis

scientific article published on 8 February 2017

Combined analysis of genome-wide association studies for Crohn disease and psoriasis identifies seven shared susceptibility loci

scientific journal article

Comparison of two exploratory dietary patterns in association with the metabolic syndrome in a Northern German population.

scientific article published in October 2014

Decreased sigmoidal ABCB1 (P-glycoprotein) expression in ulcerative colitis is associated with disease activity.

scientific article

Depletion of potential A2M risk haplotype for Alzheimer's disease in long-lived individuals

scientific article

Diagnosing fatty liver disease: a comparative evaluation of metabolic markers, phenotypes, genotypes and established biomarkers

scientific article

Diagnostics of inflammatory bowel disease

scientific article published on November 2007

Differential activity and expression of mitogen-activated protein kinases in inflammatory bowel disease

Differential p38 mitogen-activated protein kinase target phosphorylation in responders and nonresponders to infliximab

scientific article published on 01 August 2003

Dissection of the inflammatory bowel disease transcriptome using genome-wide cDNA microarrays

scientific article

Evaluation of interleukin-6 and its soluble receptor components sIL-6R and sgp130 as markers of inflammation in inflammatory bowel diseases.

scientific article

Evidence of transmission ratio distortion of DLG5 R30Q variant in general and implication of an association with Crohn disease in men

article

G protein-coupled receptor 43 is essential for neutrophil recruitment during intestinal inflammation

scientific article published on 16 November 2009

Genetic Variation in the CYP2C Monooxygenase Enzyme Subfamily Shows No Association With Longevity in a German Population

scientific article published on July 27, 2011

Genetic variation in DLG5 is associated with inflammatory bowel disease

scientific article

Genome-wide association analysis for chronic venous disease identifies EFEMP1 and KCNH8 as susceptibility loci

scientific article published on 04 April 2017

Genome-wide association analysis in sarcoidosis and Crohn's disease unravels a common susceptibility locus on 10p12.2.

scientific article

Genome-wide association study for Crohn's disease in the Quebec Founder Population identifies multiple validated disease loci

scientific article

Genome-wide association study for ulcerative colitis identifies risk loci at 7q22 and 22q13 (IL17REL).

scientific article

Haplotype structure and association to Crohn's disease of CARD15 mutations in two ethnically divergent populations.

scientific article published in January 2003

Heritability of chronic venous disease

scientific article

Improvement of arthritis and arthralgia after treatment with infliximab (Remicade) in a German prospective, open-label, multicenter trial in refractory Crohn's disease

scientific article published on 01 October 2002

Increased Tryptophan Metabolism Is Associated With Activity of Inflammatory Bowel Diseases

scientific article

Increased response and remission rates in short-duration Crohn's disease with subcutaneous certolizumab pegol: an analysis of PRECiSE 2 randomized maintenance trial data

scientific article

Low level of the mtDNA(4977) deletion in blood of exceptionally old individuals

scientific article

Metabolic Functions of Gut Microbes Associate With Efficacy of Tumor Necrosis Factor Antagonists in Patients With Inflammatory Bowel Diseases

scientific article published on 18 July 2019

Microbial pattern recognition causes distinct functional micro-RNA signatures in primary human monocytes

scientific article (publication date: 2012)

Mucus Detachment by Host Metalloprotease Meprin β Requires Shedding of Its Inactive Pro-form, which Is Abrogated by the Pathogenic Protease RgpB.

scientific article published in November 2017

No association between microsomal triglyceride transfer protein (MTP) haplotype and longevity in humans

scientific article

PopGen: population-based recruitment of patients and controls for the analysis of complex genotype-phenotype relationships

scientific article

Regulation of DMBT1 via NOD2 and TLR4 in intestinal epithelial cells modulates bacterial recognition and invasion

scientific article

Replication of signals from recent studies of Crohn's disease identifies previously unknown disease loci for ulcerative colitis

scientific article published on 27 April 2008

Reply

scientific article published on 8 May 2018

Response to infliximab treatment in Crohn's disease is not associated with mutations in the CARD15 (NOD2) gene: an analysis in 534 patients from two multicenter, prospective GCP-level trials

article

Role of the toll-like receptor 4 polymorphism Asp299Gly in longevity and myocardial infarction in German men

scientific article published on 07 April 2007

Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility

scientific article published on 5 October 2008

Sirtuin 1 (SIRT1) sequence variation is not associated with exceptional human longevity

scientific article published on 27 October 2005

Uncoupling of mucosal gene regulation, mRNA splicing and adherent microbiota signatures in inflammatory bowel disease.

scientific article

Vedolizumab is associated with changes in innate rather than adaptive immunity in patients with inflammatory bowel disease

scientific article published on 05 May 2018

[Genetic factors in longevity. Healthy living into old age--what role do genes play?]

scientific article published on 01 December 2005

mTNF reverse signalling induced by TNFα antagonists involves a GDF-1 dependent pathway: implications for Crohn's disease.

scientific article

p38 mitogen-activated protein kinase is activated and linked to TNF-alpha signaling in inflammatory bowel disease

scientific article published on 01 May 2002