List of works - Heimo Mairbäurl

Acute changes in pulmonary artery pressures due to exercise and exposure to high altitude do not cause left ventricular diastolic dysfunction

article published in 2007

Acute in vitro hypoxia and high-altitude (4,559 m) exposure decreases leukocyte oxygen consumption

scientific article published on 20 October 2010

Altered ion transporter expression in bronchial epithelium in mountaineers with high-altitude pulmonary edema

scientific article published in November 2003

Alveolar but not intravenous S-ketamine inhibits alveolar sodium transport and lung fluid clearance in rats

scientific article published on 2 June 2010

Alveolar flooding at high altitude: failure of reabsorption?

scientific article

Beta2-adrenergic stimulation blunts inhibition of epithelial ion transport by hypoxia of rat alveolar epithelial cells

scientific article published on 22 December 2009

Both tadalafil and dexamethasone may reduce the incidence of high-altitude pulmonary edema: a randomized trial

scientific article

Con: Corticosteroids Are Useful in the Management of HAPE

scientific article published on 25 August 2015

Dexamethasone but not tadalafil improves exercise capacity in adults prone to high-altitude pulmonary edema.

scientific article

Dexamethasone prevents transport inhibition by hypoxia in rat lung and alveolar epithelial cells by stimulating activity and expression of Na+-K+-ATPase and epithelial Na+ channels.

scientific article

Does High Alveolar Fluid Reabsorption Prevent HAPE in Individuals with Exaggerated Pulmonary Hypertension in Hypoxia?

scientific article published on 10 August 2015

Downregulation of the TGFβ Pseudoreceptor BAMBI in Non-Small Cell Lung Cancer Enhances TGFβ Signaling and Invasion.

scientific article

Effects of Lumacaftor/Ivacaftor Therapy on CFTR Function in Phe508del Homozygous Patients with Cystic Fibrosis.

scientific article published on 12 January 2018

Effects of high altitude exposure on cerebral hemodynamics in normal subjects

scientific article

Exercise-induced pulmonary artery hypertension a rare finding?

scientific article published on 01 January 2008

Extreme Terrestrial Environments: Life in Thermal Stress and Hypoxia. A Narrative Review.

scientific article

FXYD1 negatively regulates Na(+)/K(+)-ATPase activity in lung alveolar epithelial cells

scientific article published on 24 September 2015

Factor inhibiting HIF-1 (FIH-1) modulates protein interactions of apoptosis-stimulating p53 binding protein 2 (ASPP2).

scientific article published on 19 April 2013

Genetic Predisposition to High-Altitude Pulmonary Edema

scientific article published on 23 January 2020

HED

scholarly article

High altitude pulmonary edema: a pressure-induced leak

scientific article

High altitude pulmonary oedema.

scientific article published in July 2003

High-Mobility Group Box-1 in Ischemia-Reperfusion Injury of the Heart

article

High-altitude pulmonary hypertension is associated with a free radical-mediated reduction in pulmonary nitric oxide bioavailability ⬇️

scientific article published on September 27, 2010

Hypoxia decreases active Na transport across primary rat alveolar epithelial cell monolayers

scientific article published in April 2002

Hypoxia decreases cellular ATP demand and inhibits mitochondrial respiration of a549 cells

scientific article published on 23 September 2004

Hypoxia-induced inhibition of whole cell membrane currents and ion transport of A549 cells

scientific article published on 16 January 2004

Impairment of left atrial mechanics does not contribute to the reduction in stroke volume after active ascent to 4559 m

scientific article published on 08 November 2018

In Vitro Erythropoiesis at Different pO<sub>2</sub> Induces Adaptations That Are Independent of Prior Systemic Exposure to Hypoxia

scientific article published on 23 March 2022

In vitro hypoxia impairs beta2-adrenergic receptor signaling in primary rat alveolar epithelial cells

scientific journal article

Increased hepcidin levels in high-altitude pulmonary edema

scientific article published on 18 December 2014

Inhaled Budesonide Does Not Affect Hypoxic Pulmonary Vasoconstriction at 4559 Meter of Altitude

scientific article published on 3 January 2018

Inhaled budesonide does not prevent acute mountain sickness after rapid ascent to 4559 m

scientific article

Inhibition of alveolar Na transport and LPS causes hypoxemia and pulmonary arterial vasoconstriction in ventilated rats

scientific article published on September 2016

Intravenous S-ketamine does not inhibit alveolar fluid clearance in a septic rat model

scientific article

Iron metabolism in high altitude residents

scientific article published on 27 August 2020

K+ channel activation with minoxidil stimulates nasal-epithelial ion transport and blunts exaggerated hypoxic pulmonary hypertension

Loss or silencing of the PHD1 prolyl hydroxylase protects livers of mice against ischemia/reperfusion injury

scientific article published on 8 October 2009

MicroRNA-20a inhibits stress-induced cardiomyocyte apoptosis involving its novel target Egln3/PHD3.

scientific article published on 11 December 2011

Nasal epithelium potential difference at high altitude (4,559 m): evidence for secretion

scientific article

Neocytolysis: How to Get Rid of the Extra Erythrocytes Formed by Stress Erythropoiesis Upon Descent From High Altitude.

scientific article

No Correlation between Plasma Levels of Vascular Endothelial Growth Factor or its Soluble Receptor and Acute Mountain Sickness ⬇️

scientific article published on January 1, 2011

Oxygen transport by hemoglobin

scientific article published on April 2012

Pathogenesis of high-altitude pulmonary edema: inflammation is not an etiologic factor

scientific article

Physiological aspects of high-altitude pulmonary edema

scientific article

Preserved right ventricular function but increased right atrial contractile demand in altitude-induced pulmonary hypertension

scientific article published on 09 March 2020

Pulmonary extravascular fluid accumulation in climbers

Rapid Ascent to 4559 m Is Associated with Increased Plasma Components of the Vascular Endothelial Glycocalyx and May Be Associated with Acute Mountain Sickness

scientific article published on 17 March 2020

Rebuttal to the PRO Statement

scientific article published on 25 August 2015

Red blood cells in sports: effects of exercise and training on oxygen supply by red blood cells

scientific article

Reliability of echocardiographic speckle-tracking derived bi-atrial strain assessment under different hemodynamic conditions

scientific article published on 12 May 2017

Remote ischemic preconditioning delays the onset of acute mountain sickness in normobaric hypoxia

scientific article

Remote ischemic preconditioning does not prevent acute mountain sickness after rapid ascent to 3,450 m.

scientific article

Remote ischemic preconditioning for prevention of high-altitude diseases: fact or fiction?

scientific article published on 18 June 2015

Response to the letter: role of remote ischemic preconditioning against acute mountain sickness during early phase by Sikri and Chawla

scientific article published in August 2015

Role of Hemolysis in Red Cell Adenosine Triphosphate Release in Simulated Exercise Conditions In Vitro ⬇️

scientific article published on October 1, 2013

Role of alveolar epithelial sodium transport in high altitude pulmonary edema (HAPE).

scientific article

Salmeterol for the prevention of high-altitude pulmonary edema

The HMGB1 protein induces a metabolic type of tumour cell death by blocking aerobic respiration

scientific article published on 7 March 2016

The Hen or the Egg: Impaired Alveolar Oxygen Diffusion and Acute High-altitude Illness? ⬇️

scientific article published on 22 August 2019

The effect of endothelin-1 on alveolar fluid clearance and pulmonary edema formation in the rat.

scientific article

The geographical ancestry affects normal hemoglobin values in high-altitude residents

scientific article published on 01 October 2020

The increase in hemoglobin concentration with altitude varies among human populations

scientific article published on 30 June 2019

The role of hypoxia-induced modulation of alveolar epithelial Na+- transport in hypoxemia at high altitude

scientific article published on 01 July 2020

Transpulmonary Plasma Catecholamines in Acute High-Altitude Pulmonary Hypertension ⬇️

scientific article published on November 25, 2010

Transpulmonary plasma ET-1 and nitrite differences in high altitude pulmonary hypertension

β2-Adrenergics in hypoxia desensitize receptors but blunt inhibition of reabsorption in rat lungs

scientific journal article

List of works by Heimo Mairbäurl

Acute changes in pulmonary artery pressures due to exercise and exposure to high altitude do not cause left ventricular diastolic dysfunction

Acute in vitro hypoxia and high-altitude (4,559 m) exposure decreases leukocyte oxygen consumption

Altered ion transporter expression in bronchial epithelium in mountaineers with high-altitude pulmonary edema

Alveolar but not intravenous S-ketamine inhibits alveolar sodium transport and lung fluid clearance in rats

Alveolar flooding at high altitude: failure of reabsorption?

Beta2-adrenergic stimulation blunts inhibition of epithelial ion transport by hypoxia of rat alveolar epithelial cells

Both tadalafil and dexamethasone may reduce the incidence of high-altitude pulmonary edema: a randomized trial

Con: Corticosteroids Are Useful in the Management of HAPE

Dexamethasone but not tadalafil improves exercise capacity in adults prone to high-altitude pulmonary edema.

Dexamethasone prevents transport inhibition by hypoxia in rat lung and alveolar epithelial cells by stimulating activity and expression of Na+-K+-ATPase and epithelial Na+ channels.

Does High Alveolar Fluid Reabsorption Prevent HAPE in Individuals with Exaggerated Pulmonary Hypertension in Hypoxia?

Downregulation of the TGFβ Pseudoreceptor BAMBI in Non-Small Cell Lung Cancer Enhances TGFβ Signaling and Invasion.

Effects of Lumacaftor/Ivacaftor Therapy on CFTR Function in Phe508del Homozygous Patients with Cystic Fibrosis.

Effects of high altitude exposure on cerebral hemodynamics in normal subjects

Exercise-induced pulmonary artery hypertension a rare finding?

Extreme Terrestrial Environments: Life in Thermal Stress and Hypoxia. A Narrative Review.

FXYD1 negatively regulates Na(+)/K(+)-ATPase activity in lung alveolar epithelial cells

Factor inhibiting HIF-1 (FIH-1) modulates protein interactions of apoptosis-stimulating p53 binding protein 2 (ASPP2).

Genetic Predisposition to High-Altitude Pulmonary Edema

HED

High altitude pulmonary edema: a pressure-induced leak

High altitude pulmonary oedema.

High-Mobility Group Box-1 in Ischemia-Reperfusion Injury of the Heart

High-altitude pulmonary hypertension is associated with a free radical-mediated reduction in pulmonary nitric oxide bioavailability ⬇️

Hypoxia decreases active Na transport across primary rat alveolar epithelial cell monolayers

Hypoxia decreases cellular ATP demand and inhibits mitochondrial respiration of a549 cells

Hypoxia-induced inhibition of whole cell membrane currents and ion transport of A549 cells

Impairment of left atrial mechanics does not contribute to the reduction in stroke volume after active ascent to 4559 m

In Vitro Erythropoiesis at Different pO<sub>2</sub> Induces Adaptations That Are Independent of Prior Systemic Exposure to Hypoxia

In vitro hypoxia impairs beta2-adrenergic receptor signaling in primary rat alveolar epithelial cells

Increased hepcidin levels in high-altitude pulmonary edema

Inhaled Budesonide Does Not Affect Hypoxic Pulmonary Vasoconstriction at 4559 Meter of Altitude

Inhaled budesonide does not prevent acute mountain sickness after rapid ascent to 4559 m

Inhibition of alveolar Na transport and LPS causes hypoxemia and pulmonary arterial vasoconstriction in ventilated rats

Intravenous S-ketamine does not inhibit alveolar fluid clearance in a septic rat model

Iron metabolism in high altitude residents

K+ channel activation with minoxidil stimulates nasal-epithelial ion transport and blunts exaggerated hypoxic pulmonary hypertension

Loss or silencing of the PHD1 prolyl hydroxylase protects livers of mice against ischemia/reperfusion injury

MicroRNA-20a inhibits stress-induced cardiomyocyte apoptosis involving its novel target Egln3/PHD3.

Nasal epithelium potential difference at high altitude (4,559 m): evidence for secretion

Neocytolysis: How to Get Rid of the Extra Erythrocytes Formed by Stress Erythropoiesis Upon Descent From High Altitude.

No Correlation between Plasma Levels of Vascular Endothelial Growth Factor or its Soluble Receptor and Acute Mountain Sickness ⬇️

Oxygen transport by hemoglobin

Pathogenesis of high-altitude pulmonary edema: inflammation is not an etiologic factor

Physiological aspects of high-altitude pulmonary edema

Preserved right ventricular function but increased right atrial contractile demand in altitude-induced pulmonary hypertension

Pulmonary extravascular fluid accumulation in climbers

Rapid Ascent to 4559 m Is Associated with Increased Plasma Components of the Vascular Endothelial Glycocalyx and May Be Associated with Acute Mountain Sickness

Rebuttal to the PRO Statement

Red blood cells in sports: effects of exercise and training on oxygen supply by red blood cells

Reliability of echocardiographic speckle-tracking derived bi-atrial strain assessment under different hemodynamic conditions

Remote ischemic preconditioning delays the onset of acute mountain sickness in normobaric hypoxia

Remote ischemic preconditioning does not prevent acute mountain sickness after rapid ascent to 3,450 m.

Remote ischemic preconditioning for prevention of high-altitude diseases: fact or fiction?

Response to the letter: role of remote ischemic preconditioning against acute mountain sickness during early phase by Sikri and Chawla

Role of Hemolysis in Red Cell Adenosine Triphosphate Release in Simulated Exercise Conditions In Vitro ⬇️

Role of alveolar epithelial sodium transport in high altitude pulmonary edema (HAPE).

Salmeterol for the prevention of high-altitude pulmonary edema

The HMGB1 protein induces a metabolic type of tumour cell death by blocking aerobic respiration

The Hen or the Egg: Impaired Alveolar Oxygen Diffusion and Acute High-altitude Illness? ⬇️

The effect of endothelin-1 on alveolar fluid clearance and pulmonary edema formation in the rat.

The geographical ancestry affects normal hemoglobin values in high-altitude residents

The increase in hemoglobin concentration with altitude varies among human populations

The role of hypoxia-induced modulation of alveolar epithelial Na+- transport in hypoxemia at high altitude

Transpulmonary Plasma Catecholamines in Acute High-Altitude Pulmonary Hypertension ⬇️

Transpulmonary plasma ET-1 and nitrite differences in high altitude pulmonary hypertension

β2-Adrenergics in hypoxia desensitize receptors but blunt inhibition of reabsorption in rat lungs