List of works by John W. Huggins

Adjuvant-enhanced antibody responses to recombinant proteins correlates with protection of mice and monkeys to orthopoxvirus challenges

scientific article

An orally bioavailable antipoxvirus compound (ST-246) inhibits extracellular virus formation and protects mice from lethal orthopoxvirus Challenge

scientific article

Characterization of wild-type and cidofovir-resistant strains of camelpox, cowpox, monkeypox, and vaccinia viruses

scientific article

Comparative whole genome sequence analysis of wild-type and cidofovir-resistant monkeypoxvirus

scientific article published on 28 May 2010

Cynomolgus macaque as an animal model for severe acute respiratory syndrome

scientific article

Differentiation of Variola major and Variola minor variants by MGB-Eclipse probe melt curves and genotyping analysis.

scientific article published on 5 April 2009

Dual-probe real-time PCR assay for detection of variola or other orthopoxviruses with dried reagents

scientific article published on 10 September 2008

Experience with intravenous ribavirin in the treatment of hemorrhagic fever with renal syndrome in Korea.

scientific article published on 31 October 2008

Exploring the potential of variola virus infection of cynomolgus macaques as a model for human smallpox

scientific article

Generation of eGFP expressing recombinant Zaire ebolavirus for analysis of early pathogenesis events and high-throughput antiviral drug screening

scientific article published on February 2005

Genomic variability of monkeypox virus among humans, Democratic Republic of the Congo

scientific article published on February 2014

Immunogenicity of a highly attenuated MVA smallpox vaccine and protection against monkeypox

scientific article published on March 2004

Inhibition of Monkeypox virus replication by RNAi

scientific article published on 07 June 2021

Inhibition of monkeypox virus replication by RNA interference

scientific article

Interferon alfacon1 is an inhibitor of SARS-corona virus in cell-based models

scientific article published on 15 February 2005

Interferon-beta 1a and SARS coronavirus replication

scientific article published on February 2004

Maternal and Fetal Outcomes Among Pregnant Women With Human Monkeypox Infection in the Democratic Republic of Congo

scientific article published on 6 October 2017

Monkeypox virus detection in rodents using real-time 3'-minor groove binder TaqMan assays on the Roche LightCycler

scientific article published in September 2004

N-(3,3a,4,4a,5,5a,6,6a-Octahydro-1,3-dioxo-4,6- ethenocycloprop[f]isoindol-2-(1H)-yl)carboxamides: Identification of novel orthopoxvirus egress inhibitors

scientific article

Nonhuman primates are protected from smallpox virus or monkeypox virus challenges by the antiviral drug ST-246.

scientific article published on 06 April 2009

Potential antiviral therapeutics for smallpox, monkeypox and other orthopoxvirus infections

scientific article published on January 2003

Practical Synthesis of <scp>d</scp>- and <scp>l</scp>-2-Cyclopentenone and Their Utility for the Synthesis of Carbocyclic Antiviral Nucleosides against Orthopox Viruses (Smallpox, Monkeypox, and Cowpox Virus).

scientific article published on 30 December 2004

Practical Synthesis of d- and l-2-Cyclopentenone and Their Utility for the Synthesis of Carbocyclic Antiviral Nucleosides against Orthopox Viruses (Smallpox, Monkeypox, and Cowpox Virus) ⬇️

scientific article published on November 14, 2003

Progression of pathogenic events in cynomolgus macaques infected with variola virus

scientific article

Recombinant modified vaccinia virus Ankara provides durable protection against disease caused by an immunodeficiency virus as well as long-term immunity to an orthopoxvirus in a non-human primate

scientific article

ST-246 antiviral efficacy in a nonhuman primate monkeypox model: determination of the minimal effective dose and human dose justification

scientific article published on 17 February 2009

Smallpox and pan-orthopox virus detection by real-time 3'-minor groove binder TaqMan assays on the roche LightCycler and the Cepheid smart Cycler platforms

scientific article published on February 2004

Smallpox research activities: U.S. interagency collaboration, 2001

scientific article published on July 2002

Smallpox vaccine does not protect macaques with AIDS from a lethal monkeypox virus challenge

scientific article

Smallpox vaccine, ACAM2000: Sites and duration of viral shedding and effect of povidone iodine on scarification site shedding and immune response.

scientific article published on 27 April 2015

Susceptibility of Marmosets (Callithrix jacchus) to Monkeypox Virus: A Low Dose Prospective Model for Monkeypox and Smallpox Disease

scientific article published on 6 July 2015

The cyanobacterial lectin scytovirin displays potent in vitro and in vivo activity against Zaire Ebola virus

scientific article

The host response to smallpox: analysis of the gene expression program in peripheral blood cells in a nonhuman primate model

scholarly article

Validation of a pan-orthopox real-time PCR assay for the detection and quantification of viral genomes from nonhuman primate blood

scientific article published on 3 November 2017

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