List of works - Laurence Game

Changes in macrophage transcriptome associate with systemic sclerosis and mediate GSDMA contribution to disease risk

scientific article published on 17 January 2018

Combined ChIP-Seq and transcriptome analysis identifies AP-1/JunD as a primary regulator of oxidative stress and IL-1β synthesis in macrophages

scientific article

Exploring the use of internal and externalcontrols for assessing microarray technical performance

scientific article

Functionally Conserved Noncoding Regulators of Cardiomyocyte Proliferation and Regeneration in Mouse and Human

scientific article published on 01 February 2018

Genetic analysis of the cardiac methylome at single nucleotide resolution in a model of human cardiovascular disease

scientific article

Genetic basis of transcriptome differences between the founder strains of the rat HXB/BXH recombinant inbred panel.

scientific article published on 27 April 2012

Genome sequencing reveals loci under artificial selection that underlie disease phenotypes in the laboratory rat

scientific article published on 25 July 2013

Genomic pathology of SLE-associated copy-number variation at the FCGR2C/FCGR3B/FCGR2B locus

scientific article

Identification and biochemical analysis of a novel APOB mutation that causes autosomal dominant hypercholesterolemia

scientific article published on 13 June 2013

Integrated transcriptional profiling and linkage analysis for identification of genes underlying disease.

scientific article published on 13 February 2005

Jund is a determinant of macrophage activation and is associated with glomerulonephritis susceptibility

scientific article published on May 2008

Kcnn4 is a regulator of macrophage multinucleation in bone homeostasis and inflammatory disease

scientific article published on 14 August 2014

MiMiR--an integrated platform for microarray data sharing, mining and analysis

scientific article (publication date: 18 September 2008)

Optimisation of laboratory methods for whole transcriptomic RNA analyses in human left ventricular biopsies and blood samples of clinical relevance

scientific article published on 14 March 2019

Repeatability of published microarray gene expression analyses

scientific article

Single nucleotide analysis of cytosine methylation by whole-genome shotgun bisulfite sequencing

scientific article

Systems genetics identifies a macrophage cholesterol network associated with physiological wound healing

article

Target enrichment and high-throughput sequencing of 80 ribosomal protein genes to identify mutations associated with Diamond-Blackfan anaemia.

scientific article

Targeted genetic testing for familial hypercholesterolaemia using next generation sequencing: a population-based study

scientific article

Temporal regulation of expression of immediate early and second phase transcripts by endothelin-1 in cardiomyocytes

scientific article

The use of next-generation sequencing in clinical diagnosis of familial hypercholesterolemia

scientific article

List of works by Laurence Game

Changes in macrophage transcriptome associate with systemic sclerosis and mediate GSDMA contribution to disease risk

Combined ChIP-Seq and transcriptome analysis identifies AP-1/JunD as a primary regulator of oxidative stress and IL-1β synthesis in macrophages

Exploring the use of internal and externalcontrols for assessing microarray technical performance

Functionally Conserved Noncoding Regulators of Cardiomyocyte Proliferation and Regeneration in Mouse and Human

Genetic analysis of the cardiac methylome at single nucleotide resolution in a model of human cardiovascular disease

Genetic basis of transcriptome differences between the founder strains of the rat HXB/BXH recombinant inbred panel.

Genome sequencing reveals loci under artificial selection that underlie disease phenotypes in the laboratory rat

Genomic pathology of SLE-associated copy-number variation at the FCGR2C/FCGR3B/FCGR2B locus

Identification and biochemical analysis of a novel APOB mutation that causes autosomal dominant hypercholesterolemia

Integrated transcriptional profiling and linkage analysis for identification of genes underlying disease.

Jund is a determinant of macrophage activation and is associated with glomerulonephritis susceptibility

Kcnn4 is a regulator of macrophage multinucleation in bone homeostasis and inflammatory disease

MiMiR--an integrated platform for microarray data sharing, mining and analysis

Optimisation of laboratory methods for whole transcriptomic RNA analyses in human left ventricular biopsies and blood samples of clinical relevance

Repeatability of published microarray gene expression analyses

Single nucleotide analysis of cytosine methylation by whole-genome shotgun bisulfite sequencing

Systems genetics identifies a macrophage cholesterol network associated with physiological wound healing

Target enrichment and high-throughput sequencing of 80 ribosomal protein genes to identify mutations associated with Diamond-Blackfan anaemia.

Targeted genetic testing for familial hypercholesterolaemia using next generation sequencing: a population-based study

Temporal regulation of expression of immediate early and second phase transcripts by endothelin-1 in cardiomyocytes

The use of next-generation sequencing in clinical diagnosis of familial hypercholesterolemia