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List of works by Attallah Kappas

A Microassay for Uroporphyrinogen I Synthase, One of Three Abnormal Enzyme Activities in Acute Intermittent Porphyria, and its Application to the Study of the Genetics of this Disease ⬇️

scientific article published on March 1, 1974

A comparative study of heme degradation by NADPH-cytochrome c reductase alone and by the complete heme oxygenase system. Distinctive aspects of heme degradation by NADPH-cytochrome c reductase

scientific article published on 01 July 1982

A comparison of the utility of Dowex resin and polybenzimidazole Aurorez resin in the determination of urinary porphobilinogen concentrations

scientific article published on 01 April 1987

A defect of steroid hormone metabolism in acute intermittent porphyria.

scientific article published in July 1972

A gonadotropin releasing hormone analogue prevents cyclical attacks of porphyria

scientific article published on 01 July 1990

A heat-inducible nuclear factor that binds to the heat-shock element of the human haem oxygenase gene

scientific article

A method for interdicting the development of severe jaundice in newborns by inhibiting the production of bilirubin

scientific article

A significant role for the heme oxygenase-1 gene in endothelial cell cycle progression

scientific article published in February 2002

A single dose of Sn-mesoporphyrin prevents development of severe hyperbilirubinemia in glucose-6-phosphate dehydrogenase-deficient newborns

scientific article

Ablation of adipose-HO-1 expression increases white fat over beige fat through inhibition of mitochondrial fusion and of PGC1α in female mice

scientific article

Acetaminophen metabolism in subjects fed charcoal-broiled beef

scientific article published on 01 September 1983

Activation of heme oxygenase and heat shock protein 70 genes by stress in human hepatoma cells

scientific article published on February 1990

Acute intermittent porphyria

scientific article published on 01 December 1981

Additive effect of erythropoietin and heme on murine hematopoietic recovery after azidothymidine treatment.

scientific article

Adenoviral vector-mediated transfer of human heme oxygenase in rats decreases renal heme-dependent arachidonic acid epoxygenase activity

Adenovirus-mediated heme oxygenase-1 gene transfer into rabbit ocular tissues

scientific article published on 01 October 1995

Adipocyte heme oxygenase-1 induction attenuates metabolic syndrome in both male and female obese mice

scientific article

Adrenalectomy enhances the induction of heme oxygenase and the degradation of cytochrome P-450 in liver.

scientific article published on December 1980

Alterations in drug metabolism in workers exposed to polychlorinated biphenyls

scientific article published on August 1, 1977

An experimental model of postnatal jaundice in the suckling rat. Suppression of induced hyperbilirubinemia by Sn-protoporphyrin

scientific article

Apo A1 Mimetic Rescues the Diabetic Phenotype of HO-2 Knockout Mice via an Increase in HO-1 Adiponectin and LKBI Signaling Pathway ⬇️

scientific article published on April 4, 2012

Assays for Porphyrins, δ-Aminolevulinic-Acid Dehydratase, and Porphyrinogen Synthetase in Microliter Samples of Whole Blood: Applications to Metabolic Defects Involving the Heme Pathway ⬇️

scientific article published on September 1, 1972

Biochemical and Clinical Aspects of The Porphyrias1

scientific article

Characterization of a 142-bp fragment of the murine c-fos oncogene promoter upstream of the SIF-binding element

scientific article published on May 1994

Chemoprevention of neonatal jaundice: potency of tin-protoporphyrin in an animal model

scientific article published on 01 September 1982

Chemoprevention of severe neonatal hyperbilirubinemia

scientific article

Chloro-substituent sites and probability of co-planarity in polychlorinated biphenyls in determining uroporphyrin formation in cultured liver cells

scientific article published on December 1986

Cigarette smoking and chlorpromazine disposition and actions

scientific article published on 01 April 1982

Circulating endothelial cells are elevated in patients with type 2 diabetes mellitus independently of HbA(1)c

scientific article published on 20 January 2005

Cloning and expression of the defective genes from a patient with delta-aminolevulinate dehydratase porphyria ⬇️

scientific article published on May 1, 1992

Cloning and expression of the defective genes in delta-aminolevulinate dehydratase porphyria: compound heterozygosity in this hereditary liver disease

scientific article published on 01 January 1992

Cobalt Protoporphyrin Regulates Body Weight in Beagle Dogs: Induction of Weight Loss in Normal Animals of Stable Adult Weight ⬇️

scientific article published on January 1, 1991

Cobalt-protoporphyrin suppresses expression of genetic obesity in homozygous (fa/fa) Zucker rats

scientific article

Cobalt-protoporphyrin suppresses thyroid and testicular hormone concentrations in rat serum: a novel action of this synthetic heme analogue

scientific article published on 01 January 1987

Coexpression of erythropoietin and heme oxygenase genes in Hep3B cells

scientific article published on 01 May 1993

Comparative effects of heme and metalloporphyrins on interferon-gamma-mediated pathways in monocytic cells (THP-1).

scientific article published on April 1993

Comparative pharmacology of zinc mesoporphyrin and tin mesoporphyrin: toxic actions of zinc mesoporphyrin on hematopoiesis and progenitor cell mobilization

scientific article published on 01 January 1999

Comparative photoactivity of tin and zinc porphyrin inhibitors of heme oxygenase: pronounced photolability of the zinc compounds

scientific article

Control of Hyperbilirubinemia in Glucose-6-Phosphate Dehydrogenase-deficient Newborns Using an Inhibitor of Bilirubin Production, Sn-Mesoporphyrin ⬇️

scientific article published on May 1, 1998

Control of bilirubin production by synthetic heme analogs: pharmacologic and toxicologic considerations.

scientific article published on May 1996

Control of heme and cytochrome P-450 metabolism by inorganic metals, organometals and synthetic metalloporphyrins

scientific article

Control of heme metabolism with synthetic metalloporphyrins

scientific article

Control of heme oxygenase and plasma levels of bilirubin by a synthetic heme analogue, tin-protoporphyrin

scientific article published on 01 March 1984

Control of jaundice in preterm newborns by an inhibitor of bilirubin production: studies with tin-mesoporphyrin.

scientific article published in January 1994

Control of severe hyperbilirubinemia in full-term newborns with the inhibitor of bilirubin production Sn-mesoporphyrin

scientific article published in January 1999

Cytochrome P-450C-M/F, a new constitutive form of microsomal cytochrome P-450 in male and female rat liver with estrogen 2- and 16 alpha-hydroxylase activity

scientific article published on 01 January 1988

Cytochrome P450CMF cDNA: nucleotide sequence of P450CMF1b

scientific article

Deficient induction of uroporphyrinogen-I synthase activity in mitogen-stimulated lymphocytes from patients with acute intermittent porphyria

scientific article published on January 1, 1977

Diet and cimetidine induce comparable changes in theophylline metabolism in normal subjects

scientific article published in May 1991

Diet-hormone interactions: protein/carbohydrate ratio alters reciprocally the plasma levels of testosterone and cortisol and their respective binding globulins in man

scientific article published on 01 May 1987

Dietary regulation of cytochrome P450.

scientific article published on January 1991

Differences in inducibility of cutaneous and hepatic drug metabolizing enzymes and cytochrome P-450 by polychlorinated biphenyls and 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (DDT)

scientific article published on 01 February 1974

Differential effect of heme oxygenase-1 in endothelial and smooth muscle cell cycle progression

scientific article published on 01 September 2002

Differential effects of heme oxygenase isoforms on heme mediation of endothelial intracellular adhesion molecule 1 expression

scientific article published on 01 October 1999

Differential heme oxygenase induction by stannous and stannic ions in the heart

scientific article published on 01 March 1995

Differential responses to inducers of delta-aminolaevulinate synthase and haem oxygenase during pregnancy

scientific article

Diminished Heme Oxygenase Potentiates Cell Death: Pyrrolidinedithiocarbamate Mediates Oxidative Stress ⬇️

scientific article published on May 1, 2003

Direct comparison of Sn-mesoporphyrin, an inhibitor of bilirubin production, and phototherapy in controlling hyperbilirubinemia in term and near-term newborns

scientific article published on 01 April 1995

Disposition of tin-protoporphyrin and suppression of hyperbilirubinemia in humans

scientific article published on 01 May 1986

Distribution of metalloporphyrin inhibitors of heme oxygenase among serum transport proteins

scientific article published on 01 October 1994

Downregulation of PGC-1α Prevents the Beneficial Effect of EET-Heme Oxygenase-1 on Mitochondrial Integrity and Associated Metabolic Function in Obese Mice

scientific article published on 20 December 2016

Drug metabolism by the human hepatoma cell, Hep G2

scientific article published on 01 February 1987

Drug metabolism in normal children, lead-poisoned children, and normal adults

scientific article published on 01 February 1975

Drug-induced alterations of steroid hormone metabolism in man ⬇️

scientific article published on January 1, 1973

Effect of brussels sprouts and cabbage on drug conjugation

scientific article published on 01 February 1984

Effect of charcoal-broiled beef on antipyrine and theophylline metabolism

scientific article published on 01 April 1978

Effect of charcoal-broiled beef on phenacetin metabolism in man

scientific article published on 01 December 1976

Effect of lead and genetic factors on heme biosynthesis in the human red cell

scientific article published on April 15, 1975

Effects of a series of metalloporphyrins on adrenal, testicular and thyroid function in rats

scientific article published on 01 March 1996

Effects of oral contraceptives on vitamin metabolism

scientific article published on January 1, 1976

Effects of polychlorinated biphenyl compounds, 2,3,7,8-tetrachlorodibenzo-p-dioxin, phenobarbital and iron on hepatic uroporphyrinogen decarboxylase. Implications for the pathogenesis of porphyria

scientific article

Effects of protein and carbohydrate content of diet on drug conjugation

scientific article published on 01 September 1991

Effects of tin-porphyrins on developmental changes in hepatic cytochrome P450 content, selected P450-dependent drug-metabolizing enzyme activities and brain glutathione levels in the newborn rat.

scientific article published in January 1989

Elevated levels of heme oxygenase-1 activity and mRNA in peripheral blood adherent cells of acquired immunodeficiency syndrome patients

scientific article

Endocrine-gene interaction in the pathogenesis of acute intermittent porphyria.

scientific article

Enhanced phenacetin metabolism in human subjects fed charcoal-broiled beef

scientific article published on December 1, 1976

Enzymatic defect in a child with hereditary hepatic porphyria due to homozygous delta-aminolevulinic acid dehydratase deficiency: immunochemical studies

scientific article published on 01 December 1987

Epoxyeicosatrienoic Acids Regulate Adipocyte Differentiation of Mouse 3T3 Cells, Via PGC-1α Activation, Which Is Required for HO-1 Expression and Increased Mitochondrial Function

scientific article published on 25 May 2016

Erythrocyte uroporphyrinogen decarboxylase activity in porphyria cutanea tarda: a study of 40 consecutive patients

scientific article published on 01 September 1989

Ethnic differences in reactions to drugs and xenobiotics. Nutrition as an environmental influence on chemical metabolism in man.

scientific article

Exacerbation of Hereditary Hepatic Porphyria by Surreptitious Ingestion of an Unusual Provocative Agent — A Mouthwash Preparation ⬇️

scientific article published on May 22, 1975

Experimental hepatic porphyria: studies with steroids of physiological origin in man.

scientific article published in July 1968

Fluorometric measurement of tin-protoporphyrin in biological samples

scientific article published on 01 August 1984

Genetic, metabolic, and biochemical aspects of the porphyrias.

scientific article published on January 1981

Growth-promoting effects of iron- and cobalt- protoporphyrins on cultured embryonic cells

scientific article published on 01 August 1983

HO-1 Induction Improves The Type-1 Cardiorenal Syndrome in Mice With Impaired Angiotensin II–Induced Lymphocyte Activation ⬇️

scientific article published on June 10, 2013

HO-1 expression increases mesenchymal stem cell-derived osteoblasts but decreases adipocyte lineage

scientific article

Heat shock induction of heme oxygenase mRNA in human Hep 3B hepatoma cells

scientific article published on 01 November 1989

Heme binding to murine erythroleukemia cells. Evidence for a heme receptor

scientific article published on 01 October 1985

Heme biosynthesis and drug metabolism in mice with hereditary hemolytic anemia. Heme oxygenase induction as an adaptive response for maintaining cytochrome P-450 in chronic hemolysis ⬇️

scientific article published on February 10, 1979

Heme inhibits human immunodeficiency virus 1 replication in cell cultures and enhances the antiviral effect of zidovudine

scientific article (publication date: March 1991)

Heme oxygenase (HO-1) rescue of adipocyte dysfunction in HO-2 deficient mice via recruitment of epoxyeicosatrienoic acids (EETs) and adiponectin

scientific article published on March 2012

Heme oxygenase and the cardiovascular-renal system

scientific article

Heme oxygenase gene targeting to adipocytes attenuates adiposity and vascular dysfunction in mice fed a high-fat diet

scientific article

Heme oxygenase induction with attenuation of experimentally induced corneal inflammation

scientific article published on April 1997

Heme oxygenase inhibitors transiently increase serum ferritin concentrations without altering other acute-phase reactants in man

scientific article published on 01 July 1999

Heme oxygenase is a positive acute-phase reactant in human Hep3B hepatoma cells.

scientific article published on March 1992

Heme oxygenase-1 induction remodels adipose tissue and improves insulin sensitivity in obesity-induced diabetic rats

scientific article published on 26 January 2009

Hepatoerythropoietic porphyria: clinical, biochemical, and enzymatic studies in a three-generation family lineage

scientific article published on 01 March 1987

Hereditary hepatic porphyria due to homozygous delta-aminolevulinic acid dehydratase deficiency: studies in lymphocytes and erythrocytes

scientific article published on 01 April 1991

Hereditary tyrosinemia and the heme biosynthetic pathway. Profound inhibition of delta-aminolevulinic acid dehydratase activity by succinylacetone

scientific article

Hereditary tyrosinemia. Formation of succinylacetone-amino acid adducts

scientific article published on September 1985

Hormonal regulation of heme oxygenase induction in avian hepatocyte culture

scientific article

Human heme oxygenase-1 gene transfer lowers blood pressure and promotes growth in spontaneously hypertensive rats

scientific article

Human heme oxygenase: cell cycle-dependent expression and DNA microarray identification of multiple gene responses after transduction of endothelial cells.

scientific article published in December 2003

Human skin aryl hydrocarbon hydroxylase. Induction by coal tar ⬇️

scientific article published on November 1, 1978

Hyperbeta-lipoproteinemia in acute intermittent porphyria; preliminary report

scientific article published on 01 February 1970

Hypothalamic mechanism for cobalt protoporphyrin-induced hypophagia and weight loss: inhibition of the feeding response to NPY

scientific article published on October 1, 1992

Identification of binding sites for transcription factors NF-kappa B and AP-2 in the promoter region of the human heme oxygenase 1 gene

scientific article published on June 1994

Immunochemical detection of cytochrome P450C-M/F and NADPH-cytochrome P450 reductase in rat liver and kidney

scientific article published on 01 February 1988

Immunochemical study of uroporphyrinogen decarboxylase in a patient with mild hepatoerythropoietic porphyria

scientific article

In memoriam: Sam Granick 1909-1977 ⬇️

scientific article published on September 1, 1977

Incorporation of metalloporphyrin inhibitors of heme oxygenase into micelles and liposomes

scientific article published on 01 October 1994

Increased HO-1 levels ameliorate fatty liver development through a reduction of heme and recruitment of FGF21.

scientific article published on 02 December 2013

Increased erythrocyte uroporphyrinogen-l-synthetase, delta-aminolevulinic acid dehydratase and protoporphyrin in hemolytic anemias

scientific article published on 01 September 1977

Induction of a deficiency of steroid delta 4-5 alpha-reductase activity in liver by a porphyrinogenic drug

scientific article published in January 1977

Induction of aminolevulinate synthase and porphyrins in cultured liver cells maintained in chemically defined medium. Permissive effects of hormones on induction process ⬇️

scientific article published on April 10, 1977

Induction of drug-metabolizing enzymes and aryl hydrocarbon hydroxylase by microscope immersion oil.

scientific article published on March 1974

Induction of haem synthesis in Hep G2 human hepatoma cells by dimethyl sulphoxide. A transcriptionally activated event ⬇️

scientific article published on July 1986

Induction of hepatic cytochrome P-450 by natural steroids: relationship to the induction of delta-aminolevulinate synthase and porphyrin accumulation in the avian embryo

scientific article published on 01 September 1982

Influence of dietary protein and carbohydrate on antipyrine and theophylline metabolism in man

scientific article published on December 1, 1976

Inhibited induction of hepatic delta-aminolevulinate synthetase in pregnancy

scientific article published on May 1974

Inhibition of human immunodeficiency virus-1 reverse transcriptase by heme and synthetic heme analogs

scientific article published on January 1996

Injection of cobalt protoporphyrin into the medial nuclei of the hypothalamus elicits weight loss

scientific article published on October 1, 1992

Interactions between nutritional factors and drug biotransformations in man ⬇️

scientific article published on July 1, 1976

Interdiction of the diabetic state in NOD mice by sustained induction of heme oxygenase: possible role of carbon monoxide and bilirubin

scientific article published on 01 July 2007

Interleukin-6 down regulates the expression of transcripts encoding cytochrome P450 IA1, IA2 and IIIA3 in human hepatoma cells

scientific article published on April 30, 1992

Intestinal heme oxygenase inhibition and increased biliary iron excretion by metalloporphyrins.

scientific article

Intracerebroventricular administration of cobalt protoporphyrin elicits prolonged weight reduction in rats

scientific article published in December 1991

Intraindividual variation in drug disposition ⬇️

scientific article published on October 1, 1979

Investigations on the role of hemopexin and albumin in plasma clearance and tissue distribution of Sn-protoporphyrin

scientific article published on 01 August 1993

Lack of effect of pregnancy or hematin therapy on erythrocyte porphobilinogen deaminase activity in acute intermittent porphyria

scientific article published on 01 July 1989

Lead hazard among ironworkers. Dismantling lead-painted elevated subway line in New York City

scientific article published on July 1, 1978

Lead intoxication among demolition workers: the effect of lead on the hepatic cytochrome P-450 system in humans

scientific article published on October 1, 1977

Lead intoxication: effects on cytochrome P-450-mediated hepatic oxidations

scientific article published on February 1, 1976

Lead poisoning from art restoration and pottery work: unusual exposure source and household risk

scientific article published on January 1, 1992

Lead poisoning in an art conservator

scientific article published on 01 April 1982

Lentiviral-human heme oxygenase targeting endothelium improved vascular function in angiotensin II animal model of hypertension

scientific article

Long-lasting expression of HO-1 delays progression of type I diabetes in NOD mice

scientific article published on 29 March 2007

Long-term administration of massive doses of Sn-protoporphyrin in anemic mutant mice (sphha/sphha)

scientific article

Long-term bone marrow stromal and hemopoietic toxicity to AZT: protective role of heme and IL-1

scientific article published on February 1, 1993

Manganese and zinc blockade of enzyme induction: Studies with microsomal heme oxygenase ⬇️

scientific article published on October 1, 1979

Mechanism of Heme-Heme Oxygenase System Impairment of Endothelium Contraction in the Spontaneously Hypertensive Rat ⬇️

scientific article published on September 26, 2011

Message amplification phenotyping of an inherited delta-aminolevulinate dehydratase deficiency in a family with acute hepatic porphyria

scientific article published on October 1990

Metabolism of estradiol in liver cell culture. Differential responses of C-2 and C-16 oxidations to drugs and other chemicals that induce selective species of cytochrome P-450

scientific article

Metal induction of haem oxygenase without concurrent degradation of cytochrome P-450. Protective effects of compound SKF 525A on the haem protein

scientific article published on January 1982

Metal ion interactions in the control of haem oxygenase induction in liver and kidney

scientific article published on November 1980

Metal ion-mediated regulation of heme oxygenase induction in cultured avian liver cells

scientific article published on 01 May 1982

Microscope immersion oils: effects of skin application on cutaneous and hepatic drug-metabolizing enzymes

scientific article published on April 1975

Modulation of corneal heme oxygenase expression by oxidative stress agents

scientific article published on January 1995

Molecular aspects of the inherited porphyrias

scientific article (publication date: February 2000)

Molecular defects of uroporphyrinogen decarboxylase in a patient with mild hepatoerythropoietic porphyria

scientific article

Naive human T cells are activated and proliferate in response to the heme oxygenase-1 inhibitor tin mesoporphyrin.

scientific article published on 4 October 2010

Negative regulation of human heme oxygenase in microvessel endothelial cells by dexamethasone

scientific article published on 01 November 1999

Neurophysiological abnormalities in adolescents with type I Crigler-Najjar syndrome ⬇️

scientific article published on November 1, 1990

Nutrient regulation of chemical metabolism in humans

scientific article

Nutrition and chemical biotransformations in man ⬇️

scientific article published on November 1, 1977

Nutrition and oxidative drug metabolism in man: relative influence of dietary lipids, carbohydrate, and protein

scientific article published on 01 October 1979

Nutrition-endocrine interactions: induction of reciprocal changes in the delta 4-5 alpha-reduction of testosterone and the cytochrome P-450-dependent oxidation of estradiol by dietary macronutrients in man.

scientific article published on December 1983

Nutritional influences on chemical biotransformations in humans

scientific article published on June 1982

Overexpression of human heme oxygenase-1 attenuates endothelial cell sloughing in experimental diabetes

scientific article

Oxidative drug metabolism and inducibility by phenobarbital in sickle cell anemia

scientific article published on 01 November 1977

Partial purification of cytochrome P450 from rat brain and demonstration of estradiol hydroxylation

scientific article published in September 1987

Pharmacokinetics of tin-mesoporphyrin in man and the effects of tin-chelated porphyrins on hyperexcretion of heme pathway precursors in patients with acute inducible porphyria

scientific article published in June 1989

Pharmacologic effects of the red blood cell substitutes cross-linked and non-cross-linked hemoglobins on hematopoiesis in rabbits

scientific article published on 01 June 1999

Pharmacological and clinical aspects of heme oxygenase

scientific article

Photodynamic properties of Sn-protoporphyrin: clinical investigations and phototesting in human subjects

scientific article published on 01 February 1993

Photophysical properties of Sn-porphyrins: potential clinical implications ⬇️

scientific article published on 01 April 1988

Plumbism from airborne lead in a firing range. An unusual exposure to a toxic heavy metal

scientific article published in August 1977

Polychlorinated biphenyls: a new type of inducer of cytochrome P-448 in the liver

scientific article

Polychlorinated biphenyls: comparative effects of high and low chlorine containing Aroclors on hepatic mixed function oxidase

scientific article published on 01 May 1972

Porphyria cutanea tarda associated with the acquired immune deficiency syndrome

scientific article published on 01 May 1987

Porphyrin-heme biosynthesis in organotypic cultures of mouse dorsal root ganglia. Effects of heme and lead on porphyrin synthesis and peripheral myelin

scientific article published on August 1984

Potent heme-degrading action of antimony and antimony-containing parasiticidal agents

scientific article published on February 1981

Prenatal diagnosis of acute intermittent porphyria ⬇️

scientific article published on 01 December 1976

Preparation and properties of a solubilized form of cytochrome P-450 from chick embryo liver microsomes

scientific article published on 01 May 1971

Prevention of cyclical attacks of acute intermittent porphyria with a long-acting agonist of luteinizing hormone-releasing hormone

scientific article published on 01 September 1984

Prevention of neonatal hyperbilirubinemia by tin protoporphyrin IX, a potent competitive inhibitor of heme oxidation

scientific article

Prolonged clinical use of a heme oxygenase inhibitor: hematological evidence for an inducible but reversible iron-deficiency state

scientific article published on 01 March 1993

Prolonged induction of hepatic haem oxygenase and decreases in cytochrome P-450 content by organotin compounds

scientific article published on August 1980

Proof that Sn-protoporphyrin inhibits the enzymatic catabolism of heme in vivo. Suppression of 14CO generation from radiolabeled endogenous and exogenous heme sources

scientific article published on April 1987

Protective effect of HO-1 against oxidative stress in human hepatoma cell line (HepG2) is independent of telomerase enzyme activity

scientific article published on December 2002

Protective effect of Sn-protoporphyrin against doxorubicin-induced perturbations of heme metabolism

scientific article published on 01 January 1990

Purification and properties of bovine spleen heme oxygenase. Amino acid composition and sites of action of inhibitors of heme oxidation

scientific article published on 01 July 1982

Purification and properties of human erythrocyte uroporphyrinogen decarboxylase: immunological demonstration of the enzyme defect in porphyria cutanea tarda

scientific article published on 01 January 1983

Purification and properties of uroporphyrinogen decarboxylase from human erythrocytes. A single enzyme catalyzing the four sequential decarboxylations of uroporphyrinogens I and III

scientific journal article

Radiometric analysis of biological oxidations in man: sex differences in estradiol metabolism

scientific article

Recent Advances in Porphyrin Metabolism ⬇️

scientific article published on January 1, 1971

Reduction of the C2 and C4 vinyl groups of Sn-protoporphyrin to form Sn-mesoporphyrin markedly enhances the ability of the metalloporphyrin to inhibit in vivo heme catabolism

scientific article published on 01 May 1987

Regulation of Cyclooxygenase by the Heme-Heme Oxygenase System in Microvessel Endothelial Cells ⬇️

scientific article published on January 1, 2002

Regulation of drug metabolism in man by environmental factors

scientific article

Regulation of food intake and body weight by cobalt porphyrins in animals

scientific article

Regulation of food intake and body weight in rats by the synthetic heme analogue cobalt protoporphyrin

scientific article published in December 1991

Regulation of human drug metabolism by dietary factors.

scientific article published in January 1980

Regulation of human heme oxygenase in endothelial cells by using sense and antisense retroviral constructs

scientific article

Relationship of suppression of the androgenic axis by cobalt-protoporphyrin to its effects on weight loss and hepatic heme oxygenase induction

scientific article published in January 1987

Sequential induction of enzymes in the heme biosynthetic pathway during erythroid differentiation

scientific article published on 01 December 1975

Small interfering RNA targeting heme oxygenase-1 enhances ischemia-reperfusion-induced lung apoptosis.

scientific article published on 18 December 2003

Sn-Mesoporphyrin Interdiction of Severe Hyperbilirubinemia in Jehovah’s Witness Newborns as an Alternative to Exchange Transfusion ⬇️

scientific article published on December 1, 2001

Sn-mesoporphyrin Suppression of Hyperbilirubinemia in EHBR/Eis Rats, an Animal Model of Dubin-Johnson Syndrome ⬇️

scientific article published on March 1, 1998

Sn-protoporphyrin blocks the increase in serum bilirubin levels that develops postnatally in homozygous Gunn rats

scientific article published on March 1988

Sn-protoporphyrin inhibition of fetal and neonatal brain heme oxygenase. Transplacental passage of the metalloporphyrin and prenatal suppression of hyperbilirubinemia in the newborn animal

scientific article

Sn-protoporphyrin lowers serum bilirubin levels, decreases biliary bilirubin output, enhances biliary heme excretion and potently inhibits hepatic heme oxygenase activity in normal human subjects

scientific article published in May 1988

Sn-protoporphyrin rapidly and markedly enhances the heme saturation of hepatic tryptophan pyrrolase. Evidence that this synthetic metalloporphyrin increases the functional content of heme in the liver

scientific article

Sn-protoporphyrin suppresses chemically induced experimental hepatic porphyria. Potential clinical implications

scientific article

Sn-protoporphyrin use in the management of hyperbilirubinemia in term newborns with direct Coombs-positive ABO incompatibility

scientific article published on 01 April 1988

Some Biochemical and Clinical Aspects of Lead Intoxication

scientific article published on January 1, 1978

Steroid control of porphyrin and heme biosynthesis: a new biological function of steroid hormone metabolites ⬇️

scientific article

Steroid induction of delta-aminolevulinic acid synthase and porphyrins in liver. Structure-activity studies and the permissive effects of hormones on the induction process ⬇️

scientific article (publication date: 25 October 1979)

Steroid induction of porphyrin synthesis in liver cell culture

scientific article published on 01 January 1967

Steroid induction of porphyrin synthesis in liver cell culture. I. Structural basis and possible physiological role in the control of heme formation

scientific article published on 01 October 1967

Steroid induction of porphyrin synthesis in liver cell culture. II. The effects of heme, uridine diphosphate glucuronic acid, and inhibitors of nucleic acid and protein synthesis on the induction process.

scientific article

Stimulation of hemoglobin synthesis in chick blastoderms by certain 5beta androstane and 5beta pregnane steroids ⬇️

scientific article

Stimulation of hepatic porphyrin synthesis in tissue culture by sera of patients with acute porphyria

scientific article published on 01 January 1969

Stimulation of mammalian erythropoiesis by 5beta-H steroid metabolites

scientific article

Stimulation of mammalian erythropoiesis by metabolites of steroid hormones

scientific article published in January 1970

Stimulators and Inhibitors of Hepatic Porphyrin Formation in Human Sera ⬇️

scientific article published on April 1, 1974

Stimulatory effect of brussels sprouts and cabbage on human drug metabolism

scientific article published on 01 January 1979

Studies in lead poisoning. I. Microanalysis of erythrocyte protoporphyrin levels by spectrophotometry in the detection of chronic lead intoxication in the subclinical range

scientific article published on 01 August 1973

Studies in lead poisoning. II. Correlation between the ratio of activated to inactivated delta-aminolevulinic acid dehydratase of whole blood and the blood lead level

scientific article published on 01 August 1973

Studies in porphyria IX: Detection of the gene defect of erythropoietic protoporphyria in mitogen-stimulated human lymphocytes

scientific article published on 01 January 1979

Studies in porphyria. IV. Expression of the gene defect of acute intermittent porphyria in cultured human skin fibroblasts and amniotic cells: prenatal diagnosis of the porphyric trait ⬇️

scientific article (publication date: September 1975)

Studies in porphyria. V. Drug oxidation rates in hereditary hepatic porphyria.

scientific article published in January 1976

Studies in porphyria. VI. Biosynthesis of porphyrins in mammalian skin and in the skin of porphyric patients

scientific article

Studies in porphyria. VII. Induction of uroporphyrinogen-I synthase and expression of the gene defect of acute intermittent porphyria in mitogen-stimulated human lymphocytes ⬇️

scientific article published on February 1, 1978

Studies in porphyria. VIII. Relationship of the 5 alpha-reductive metabolism of steroid hormones to clinical expression of the genetic defect in acute intermittent porphyria

scientific article published on April 1979

Studies in porphyria: functional evidence for a partial deficiency of ferrochelatase activity in mitogen-stimulated lymphocytes from patients with erythropoietic protoporphyria

scientific article published on April 1982

Studies of the influence of chloro-substituent sites and conformational energy in polychlorinated biphenyls on uroporphyrin formation in chick-embryo liver cell cultures

scientific article

Studies on porphyrin-heme biosynthesis in organotypic cultures of chick dorsal root ganglia. II. The effect of lead

scientific article published on August 1979

Studies on porphyrin-heme biosynthesis in organotypic cultures of chick dorsal root ganglion. I. Observations on neuronal and non-neuronal elements ⬇️

scientific article published on 01 September 1978

Studies on the inheritance of human erythrocyte delta-aminolevulinate dehydratase and uroporphyrinogen synthetase

scientific article published on 01 January 1973

Studies on the mechanism of Sn-protoporphyrin suppression of hyperbilirubinemia. Inhibition of heme oxidation and bilirubin production

scientific article

Studies with the haeme oxygenase inhibitor Sn-protoporphyrin in patients with primary biliary cirrhosis and idiopathic haemochromatosis

scientific article

Study of differences of estradiol metabolism between men and women by means of in vivo radiometric analysis

scientific article published on 01 January 1980

Succinylacetone and delta-aminolevulinic acid dehydratase in hereditary tyrosinemia: immunochemical study of the enzyme

scientific article published on 01 July 1990

Succinylacetone inhibits delta-aminolevulinate dehydratase and potentiates the drug and steroid induction of delta-aminolevulinate synthase in liver

scientific article published on 01 January 1982

Suppression of bilirubin production in the Crigler-Najjar type I syndrome: studies with the heme oxygenase inhibitor tin-mesoporphyrin ⬇️

scientific article published on February 1, 1992

Suppression of hyperbilirubinemia in the rat neonate by chromium-protoporphyrin. Interactions of metalloporphyrins with microsomal heme oxygenase of human spleen

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Synergistic effect of heme and IL-1 on hematopoietic stromal regeneration after radiation

scientific article published on 01 November 1993

Synthetic metalloporphyrins: a class of compounds of pharmacological interest

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THE INDUCTION OF delta-AMINOLEVULINIC ACID SYNTHETASE in vivo IN CHICK EMBRYO LIVER BY NATURAL STEROIDS.

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Targeted delivery of a heme oxygenase inhibitor with a lyophilized liposomal tin mesoporphyrin formulation

scientific article published on 01 May 1993

Targeting of heme oxygenase inhibitors to the spleen markedly increases their ability to diminish bilirubin production

scientific article published on 01 December 1989

The Biological Significance and Physiological Role of Heme Oxygenase

scientific article published in 1996

The Influence of Dietary Protein and Carbohydrate on the Principal Oxidative Biotransformations of Estradiol in Normal Subjects*

The cytochrome P-450-depleted animal: an experimental model for in vivo studies in chemical biology

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The effect of environmental light exposure on drug-induced porphyria in the rat

scientific article published on 01 December 1976

The effects of acute-phase inducers and dimethyl sulphoxide on delta-aminolaevulinate synthase activity in human HepG2 hepatoma cells

scientific article published on April 1989

The in vitro and in vivo inhibition of intestinal heme oxygenase by tin-protoporphyrin

scientific article published on 01 January 1989

The induction of a carcinogen-metabolizing enzyme in human skin

scientific article published on January 1973

The influence of organometals on heme metabolism. In vivo and in vitro studies with organotins

scientific article published on 01 January 1982

The influence of steroid hormone metabolites on the in vitro development of erythroid colonies derived from human bone marrow ⬇️

scientific article published on June 1, 1979

The liver excretes large amounts of heme into bile when heme oxygenase is inhibited competitively by Sn-protoporphyrin

scientific article published on February 1985

The molecular defect of ferrochelatase in a patient with erythropoietic protoporphyria

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The occurrence of molecular interactions among NADPH-cytochrome c reductase, heme oxygenase, and biliverdin reductase in heme degradation

scientific article published on 01 July 1982

The occurrence of substances in human plasma capable of inducing the enzyme delta-aminolevulinate synthetase in liver cells

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The oxidative degradation of heme c by the microsomal heme oxygenase system

scientific article published on 01 July 1982

The potent heme oxygenase inducing action of arsenic and parasiticidal arsenicals

scientific article published on 01 January 1981

The potent induction of intestinal heme oxygenase by the organotin compound, bis(tri-n-butyltin)oxide

scientific article published on 01 March 1984

The regulation of porphyrin and heme synthesis

scientific article published on 01 October 1968

The role of inorganic metals and metalloporphyrins in the induction of haem oxygenase and heat-shock protein 70 in human hepatoma cells

scientific article published on March 1993

Thyroid hormone regulation of heme oxidation in the liver

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Tin(Sn+4)-diiododeuteroporphyrin; an in vitro and in vivo inhibitor of heme oxygenase with substantially reduced photoactive properties

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Tin-mesoporphyrin inhibits heme oxygenase activity and heme-iron absorption in the intestine.

scientific article published in November 1993

Tin-protoporphyrin and long wave length ultraviolet light in treatment of psoriasis

scientific article published on June 1989

Tin-protoporphyrin inhibits heme oxygenase and prevents the decline in hepatic heme and cytochrome P-450 contents produced in nude mice by tumor transplantation

scientific article published on 01 January 1988

Tin-protoporphyrin suppression of hyperbilirubinemia in mutant mice with severe hemolytic anemia

scientific article published on 01 May 1983

Tissue distribution and disposition of tin-protoporphyrin, a potent competitive inhibitor of heme oxygenase

scientific article published on 01 February 1984

Tissue distribution of synthetic heme analogues: studies with tin, chromium, and zinc mesoporphyrins

scientific article published in March 1996

Transfection of the human heme oxygenase gene into rabbit coronary microvessel endothelial cells: protective effect against heme and hemoglobin toxicity

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Treatment of hyperbilirubinemia pharmacologic approach SnMP(tin-mesoporphyrin).

scientific article published in December 2001

Up-regulation of heme oxygenase provides vascular protection in an animal model of diabetes through its antioxidant and antiapoptotic effects

scientific article published on 07 September 2006

Zinc porphyrins: potent inhibitors of hematopoieses in animal and human bone marrow

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delta-Aminolaevulinate synthase in human HepG2 hepatoma cells. Repression by haemin and induction by chemicals

scientific article published on September 1989

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