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List of works by Frederic G. Barr

A Novel Algorithm for Simplification of Complex Gene Classifiers in Cancer ⬇️

scientific article published on August 2, 2013

A call to ARMS: targeting thePAX3-FOXO1gene in alveolar rhabdomyosarcoma ⬇️

scientific article published on February 25, 2013

A recurrent neomorphic mutation in MYOD1 defines a clinically aggressive subset of embryonal rhabdomyosarcoma associated with PI3K-AKT pathway mutations

scientific article

ALK expression in rhabdomyosarcomas: correlation with histologic subtype and fusion status.

scientific article

Analysis of genetic events that modulate the oncogenic and growth suppressive activities of the PAX3-FKHR fusion oncoprotein

scientific article published on 12 February 2007

Analysis of the transforming and growth suppressive activities of the PAX3-FKHR oncoprotein

scientific article published on September 2004

CDK4 Amplification Reduces Sensitivity to CDK4/6 Inhibition in Fusion-Positive Rhabdomyosarcoma

scientific article

CXCR4-SDF-1 signaling is active in rhabdomyosarcoma cells and regulates locomotion, chemotaxis, and adhesion.

scientific article published in October 2002

Chromosomal translocations and sarcomas

scientific article

Chromosome translocations in sarcomas and the emergence of oncogenic transcription factors

scientific article

Classification of rhabdomyosarcoma and its molecular basis.

scientific article

Clonality and evolutionary history of rhabdomyosarcoma

scientific article

Co-expression of alternatively spliced forms of PAX3, PAX7, PAX3-FKHR and PAX7-FKHR with distinct DNA binding and transactivation properties in rhabdomyosarcoma.

scientific article published on May 2005

Comprehensive genomic analysis of rhabdomyosarcoma reveals a landscape of alterations affecting a common genetic axis in fusion-positive and fusion-negative tumors

scientific article published on 23 January 2014

Contributors

Correlation between histology and PAX/FKHR fusion status in alveolar rhabdomyosarcoma: a report from the Children's Oncology Group

scientific article published in June 2007

Credentialing a preclinical mouse model of alveolar rhabdomyosarcoma

scientific article published on April 2009

Dense pattern of embryonal rhabdomyosarcoma, a lesion easily confused with alveolar rhabdomyosarcoma: a report from the Soft Tissue Sarcoma Committee of the Children's Oncology Group

scientific article

Desmoplastic small round cell tumor of the kidney in childhood

scientific article published on 01 April 2007

Detection and diagnostic utilization of placental alkaline phosphatase in muscular tissue and tumors with myogenic differentiation

scientific article published on 01 December 2002

Diagnostic applications of chromosomal translocations in bone and soft tissue sarcomas.

scientific article published in September 2004

Distinct methylation profiles characterize fusion-positive and fusion-negative rhabdomyosarcoma.

scientific article published on 31 July 2015

Embryonal and alveolar rhabdomyosarcoma of parameningeal sites in adults: a report of 13 cases

scientific article published on 22 October 2008

Evidence for an unanticipated relationship between undifferentiated pleomorphic sarcoma and embryonal rhabdomyosarcoma

scientific article

Examination of gene fusion status in archival samples of alveolar rhabdomyosarcoma entered on the Intergroup Rhabdomyosarcoma Study-III trial: a report from the Children's Oncology Group

scientific article published on May 2006

Fusion genes in solid tumors: the possibilities and the pitfalls.

scientific article

Fusion transcriptome profiling provides insights into alveolar rhabdomyosarcoma

scientific article

Fusion-negative alveolar rhabdomyosarcoma: modification of risk stratification is premature

scientific article published on 09 August 2010

Fusions involving PAX and FOX genes in the molecular pathogenesis of alveolar rhabdomyosarcoma: recent advances

scientific article

Genetic heterogeneity in the alveolar rhabdomyosarcoma subset without typical gene fusions

scientific article published on 01 August 2002

Genomic and clinical analyses of 2p24 and 12q13-q14 amplification in alveolar rhabdomyosarcoma: a report from the Children's Oncology Group

scientific article published on August 2009

Genomic and clinical analysis of amplification of the 13q31 chromosomal region in alveolar rhabdomyosarcoma: a report from the Children's Oncology Group

scientific article

Genomic and clinical analysis of fusion gene amplification in rhabdomyosarcoma: a report from the Children's Oncology Group

scientific article

Genomic gains and losses are similar in genetic and histologic subsets of rhabdomyosarcoma, whereas amplification predominates in embryonal with anaplasia and alveolar subtypes

scientific article published on 01 March 2002

Hedgehog pathway activity in pediatric embryonal rhabdomyosarcoma and undifferentiated sarcoma: a report from the Children's Oncology Group.

scientific article

High expression of the PAX3-FKHR oncoprotein is required to promote tumorigenesis of human myoblasts

scientific article

Histology, Fusion Status, and Outcome in Alveolar Rhabdomyosarcoma With Low-Risk Clinical Features: A Report From the Children's Oncology Group

scientific article

Histology, fusion status, and outcome in metastatic rhabdomyosarcoma: A report from the Children's Oncology Group.

scientific article

Human Rhabdomyosarcoma Cell Lines for Rhabdomyosarcoma Research: Utility and Pitfalls ⬇️

scientific article published on July 17, 2013

Human rhabdomyosarcoma cells express functional erythropoietin receptor: Potential therapeutic implications

scientific article published on 24 September 2015

Human rhabdomyosarcoma cells express functional pituitary and gonadal sex hormone receptors: Therapeutic implications

scientific article published on 11 March 2016

Identification of PAX3-FKHR-regulated genes differentially expressed between alveolar and embryonal rhabdomyosarcoma: focus on MYCN as a biologically relevant target

scientific article

Identification of target genes regulated by PAX3 and PAX3-FKHR in embryogenesis and alveolar rhabdomyosarcoma

scientific article

Immunophenotype of desmoplastic small round cell tumors as detected in cases with EWS-WT1 gene fusion product

scientific article published on 01 March 2003

Impact of SYT-SSX fusion type on the clinical behavior of synovial sarcoma: a multi-institutional retrospective study of 243 patients.

scientific article

Inducible short-term and stable long-term cell culture systems reveal that the PAX3-FKHR fusion oncoprotein regulates CXCR4, PAX3, and PAX7 expression

scientific article

Looking downstream of sarcoma-associated chimeric transcription factors: when is a target really a target?

scientific article

Malignant round cell tumor of bone with EWSR1-NFATC2 gene fusion.

scientific article published on 4 July 2014

Mediastinal synovial sarcoma: report of two cases with molecular genetic analysis

scientific article published in February 2002

Molecular diagnosis of ewing family tumors: too many fusions... ?

scientific article

Molecular pathogenesis of rhabdomyosarcoma

scientific article

Myogenin, AP2β, NOS-1, and HMGA2 are surrogate markers of fusion status in rhabdomyosarcoma: a report from the soft tissue sarcoma committee of the children's oncology group

scientific article

New Treatments for Rhabdomyosarcoma: the Importance of Target Practice

scientific article published on 13 December 2011

Oncogene Mutation Profiling of Pediatric Solid Tumors Reveals Significant Subsets of Embryonal Rhabdomyosarcoma and Neuroblastoma with Mutated Genes in Growth Signaling Pathways ⬇️

scientific article published on December 5, 2011

Overlapping and distinct role of CXCR7-SDF-1/ITAC and CXCR4-SDF-1 axes in regulating metastatic behavior of human rhabdomyosarcomas

scientific article published in December 2010

PAX-FOXO1fusion status drives unfavorable outcome for children with rhabdomyosarcoma: A children's oncology group report ⬇️

scientific article published on March 22, 2013

PAX3-FKHR and PAX7-FKHR gene fusions are prognostic indicators in alveolar rhabdomyosarcoma: a report from the children's oncology group

scientific article (publication date: June 2002)

PAX3-FOXO1 Establishes Myogenic Super Enhancers and Confers BET Bromodomain Vulnerability.

scientific article published on 26 April 2017

PAX3-FOXO1 is essential for tumour initiation and maintenance but not recurrence in a human myoblast model of rhabdomyosarcoma

scientific article published on 31 January 2017

PDGF-A, PDGF-Rbeta, TGFbeta3 and bone morphogenic protein-4 in desmoplastic small round cell tumors with EWS-WT1 gene fusion product and their role in stromal desmoplasia: an immunohistochemical study.

scientific article published in March 2005

Phenotypic profiling with a living biobank of primary rhabdomyosarcoma unravels disease heterogeneity and AKT sensitivity

scientific article published on 15 September 2020

RasGRF1 regulates proliferation and metastatic behavior of human alveolar rhabdomyosarcomas

scientific article published on 28 June 2012

Refinement of risk stratification for childhood rhabdomyosarcoma using FOXO1 fusion status in addition to established clinical outcome predictors: A report from the Children's Oncology Group

scientific article published on 27 August 2019

Regulation of expression of stromal-derived factor-1 receptors: CXCR4 and CXCR7 in human rhabdomyosarcomas

scientific article published on 12 January 2010

Relationship of DNA methylation to mutational changes and transcriptional organization in fusion-positive and fusion-negative rhabdomyosarcoma

scientific article published on 15 January 2019

Rhabdomyosarcoma

scientific article published on 7 January 2019

Rhabdomyosarcoma: current challenges and their implications for developing therapies.

scientific article

Rhabdomyosarcomas utilize developmental, myogenic growth factors for disease advantage: a report from the Children's Oncology Group

scientific article published on March 2006

Role of fusion subtype in Ewing sarcoma

scientific article published on 22 March 2010

Sclerosing rhabdomyosarcomas in children and adolescents: a clinicopathologic review of 13 cases from the Intergroup Rhabdomyosarcoma Study Group and Children's Oncology Group

scientific article

Sclerosing rhabdomyosarcomas in children and adolescents: a clinicopathologic review of 13 cases from the Intergroup Rhabdomyosarcoma Study Group and Children's Oncology Group

scientific article published on 01 January 2005

TRIG on TRACK: educating pathology residents in genomic medicine

scientific article published on 01 May 2012

The HDAC3–SMARCA4–miR-27a axis promotes expression of the PAX3:FOXO1 fusion oncogene in rhabdomyosarcoma

scientific article published on 20 November 2018

The expression and function of PAX3 in development and disease.

scientific article published on 5 August 2018

The impact of genetics on sarcoma diagnosis: an evolving science

scientific article published on 01 September 2006

The paternally imprinted DLK1-GTL2 locus is differentially methylated in embryonal and alveolar rhabdomyosarcomas

scientific article published on 29 October 2013

Therapeutic Approaches Targeting PAX3-FOXO1 and Its Regulatory and Transcriptional Pathways in Rhabdomyosarcoma

scientific article published on 28 October 2018

Unique patterns of allelic imbalance distinguish type 1 from type 2 sporadic papillary renal cell carcinoma

scientific article published on September 2002

Use of a novel FISH assay on paraffin-embedded tissues as an adjunct to diagnosis of alveolar rhabdomyosarcoma

scientific article published on 01 June 2006

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