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List of works by Lutz Frölich

1st Conference Clinical Trials on Alzheimer’s Disease September 17-18-19, 2008 School of Medecine Montpellier, France

article

A metabolite-based machine learning approach to diagnose Alzheimer-type dementia in blood: Results from the European Medical Information Framework for Alzheimer disease biomarker discovery cohort

scientific article published on 18 December 2019

A multicenter (1)H-MRS study of the medial temporal lobe in AD and MCI.

scientific article

APOE ε4 genotype-dependent cerebrospinal fluid proteomic signatures in Alzheimer's disease

scientific article published on 27 May 2020

APOE-dependent phenotypes in subjects with mild cognitive impairment converting to Alzheimer's disease

scientific article

Alzheimer's disease associated with mutations in presenilin 2 is rare and variably penetrant.

scientific article published on July 1996

Alzheimer's disease risk variants modulate endophenotypes in mild cognitive impairment

scientific article

Amyloid beta peptide ratio 42/40 but not A beta 42 correlates with phospho-Tau in patients with low- and high-CSF A beta 40 load

scientific article published on 24 January 2007

Amyloid beta peptides in plasma in early diagnosis of Alzheimer's disease: A multicenter study with multiplexing

scientific article published on 5 August 2009

Apolipoprotein E-dependent load of white matter hyperintensities in Alzheimer's disease: a voxel-based lesion mapping study

scientific article published on 15 May 2015

Association of Cerebral Amyloid-β Aggregation With Cognitive Functioning in Persons Without Dementia

scientific article published on 29 November 2017

Association of N-acetylaspartate and cerebrospinal fluid Aβ42 in dementia

scientific article published in January 2011

Association of SORL1 gene variants with Alzheimer's disease

scientific article published on 3 February 2009

Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17

scientific article

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 01 September 2019

Biomarker validation of a cued recall memory deficit in prodromal Alzheimer disease

scientific article published on 11 January 2012

Biomarker-based prognosis for people with mild cognitive impairment (ABIDE): a modelling study

scientific article published on 13 September 2019

Cerebrospinal Fluid Biomarkers and Clinical Progression in Patients with Subjective Cognitive Decline and Mild Cognitive Impairment

scientific article published on 13 May 2017

Cerebrospinal fluid biomarkers of neurodegeneration, synaptic integrity, and astroglial activation across the clinical Alzheimer's disease spectrum

scientific article published on 08 March 2019

Cerebrospinal fluid total tau levels indicate aberrant neuronal plasticity in Alzheimer's disease

scientific article published on 03 November 2020

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

scientific article (publication date: May 2011)

Common variants in Alzheimer's disease and risk stratification by polygenic risk scores

scientific article published on 7 June 2021

Comparison of Different Matrices as Potential Quality Control Samples for Neurochemical Dementia Diagnostics

scientific article published in March 2016

Consensus guidelines for lumbar puncture in patients with neurological diseases

scientific article

Dickkopf-1 Overexpression in vitro Nominates Candidate Blood Biomarkers Relating to Alzheimer's Disease Pathology

scientific article published on 20 August 2020

Discovery and validation of plasma proteomic biomarkers relating to brain amyloid burden by SOMAscan assay

scientific article published on 05 September 2019

Drug development in Alzheimer's disease: the path to 2025

scientific article

Early and differential diagnosis of dementia and mild cognitive impairment: design and cohort baseline characteristics of the German Dementia Competence Network

scientific article

Erratum: Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

scholarly article published in Nature Genetics

Evolution of Abeta42 and Abeta40 levels and Abeta42/Abeta40 ratio in plasma during progression of Alzheimer's disease: a multicenter assessment

scientific article

Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease

scientific article (publication date: 15 November 2010)

Genetic interaction of PICALM and APOE is associated with brain atrophy and cognitive impairment in Alzheimer's disease

scientific article published on 6 March 2014

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 28 February 2019

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

scientific article

Incremental value of biomarker combinations to predict progression of mild cognitive impairment to Alzheimer's dementia

scientific article published on 10 October 2017

Inflammatory biomarkers in Alzheimer's disease plasma.

scientific article published on 30 April 2019

Influence of SORL1 gene variants: association with CSF amyloid-beta products in probable Alzheimer's disease

scientific article

Investigation of the role of rare TREM2 variants in frontotemporal dementia subtypes

scientific article published on 20 June 2014

Left anterior temporal lobe sustains naming in Alzheimer's dementia and mild cognitive impairment

scientific article published on December 2011

Lithium trial in Alzheimer's disease: a randomized, single-blind, placebo-controlled, multicenter 10-week study.

scientific article published on June 2009

Longitudinal cerebrospinal fluid biomarker trajectories along the Alzheimer's disease continuum in the BIOMARKAPD study

scientific article published on 06 April 2019

Measurement of ERK 1/2 in CSF from patients with neuropsychiatric disorders and evidence for the presence of the activated form

scientific article

Measurements of medial temporal lobe atrophy for prediction of Alzheimer's disease in subjects with mild cognitive impairment

scientific article

Multicentre variability of MRI-based medial temporal lobe volumetry in Alzheimer's disease

scientific article

On the path to 2025: understanding the Alzheimer's disease continuum

scientific article published on 9 August 2017

Performance and complications of lumbar puncture in memory clinics: Results of the multicenter lumbar puncture feasibility study

scientific article published on 11 September 2015

Prediction of Alzheimer disease in subjects with amnestic and nonamnestic MCI.

scientific article published on 27 February 2013

Prevalence and prognosis of Alzheimer's disease at the mild cognitive impairment stage

scientific article published on 17 February 2015

Primary fatty amides in plasma associated with brain amyloid burden, hippocampal volume, and memory in the European Medical Information Framework for Alzheimer's Disease biomarker discovery cohort

scientific article published on 08 May 2019

SNAP-25 is a promising novel cerebrospinal fluid biomarker for synapse degeneration in Alzheimer's disease

scientific article

SUCLG2 identified as both a determinator of CSF Aβ1-42 levels and an attenuator of cognitive decline in Alzheimer's disease

scientific article

Soluble amyloid precursor proteins in the cerebrospinal fluid as novel potential biomarkers of Alzheimer's disease: a multicenter study

scientific article published on 29 July 2008

Targets of antidementive therapy: drugs with a specific pharmacological mechanism of action

scientific article published on January 2004

The Central Biobank and Virtual Biobank of BIOMARKAPD: A Resource for Studies on Neurodegenerative Diseases

scientific article

The European DTI Study on Dementia - A multicenter DTI and MRI study on Alzheimer's disease and Mild Cognitive Impairment

scientific article published on April 2016

The frequency and influence of dementia risk factors in prodromal Alzheimer's disease

scientific article published on 08 April 2017

The future of Alzheimer's disease: the next 10 years

scientific article

The role of variation at AβPP, PSEN1, PSEN2, and MAPT in late onset Alzheimer's disease

scientific article

Validation of Plasma Proteomic Biomarkers Relating to Brain Amyloid Burden in the EMIF-Alzheimer's Disease Multimodal Biomarker Discovery Cohort

scientific article published on 01 January 2020

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