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List of works by Rosemary A. Kozar

A High Fresh Frozen Plasma: Packed Red Blood Cell Transfusion Ratio Decreases Mortality in All Massively Transfused Trauma Patients Regardless of Admission International Normalized Ratio ⬇️

scientific article published on August 1, 2011

A multidisciplinary clinical pathway decreases rib fracture-associated infectious morbidity and mortality in high-risk trauma patients

scientific article published on 01 December 2006

A normal platelet count may not be enough: the impact of admission platelet count on mortality and transfusion in severely injured trauma patients

scientific article published on August 1, 2011

A predictive model for mortality in massively transfused trauma patients

scientific article published in August 2011

A randomized controlled pilot trial of modified whole blood versus component therapy in severely injured patients requiring large volume transfusions

scientific article published in October 2013

A randomized trial of supplemental parenteral nutrition in underweight and overweight critically ill patients: the TOP-UP pilot trial

scientific article

A survey of American Association for the Surgery of Trauma member practices in the management of blunt splenic injury

scientific article published in May 2011

ADAMTS-13 in traumatic brain injury?

scientific article published on 01 September 2018

Abdominal compartment syndrome: the cause or effect of postinjury multiple organ failure

scientific article published on December 2003

Abdominal complications after severe burns

scientific article published on 26 March 2009

Acute lower extremity compartment syndrome (ALECS) screening protocol in critically ill trauma patients

scientific article published on 01 August 2007

Adiponectin in Fresh Frozen Plasma Contributes to Restoration of Vascular Barrier Function After Hemorrhagic Shock

scientific article

Admission rapid thrombelastography can replace conventional coagulation tests in the emergency department: experience with 1974 consecutive trauma patients

scientific article published in September 2012

Admission rapid thrombelastography predicts development of pulmonary embolism in trauma patients

scientific article published on 01 June 2012

Age is a predictor for mortality after blunt splenic injury

scientific article published on 06 February 2020

Alpha-melanocyte-stimulating hormone protects against mesenteric ischemia-reperfusion injury

scientific article published on 01 June 2002

Alterations in content and localization of defensins in rat ileum and jejunum following ischemia-reperfusion. Specific peptides, in specific places, for specific jobs? ⬇️

scientific article published on February 23, 2011

American Society for Enhanced Recovery and Perioperative Quality Initiative Joint Consensus Statement on Nutrition Screening and Therapy Within a Surgical Enhanced Recovery Pathway

scientific article

American Society for Enhanced Recovery and Perioperative Quality Initiative Joint Consensus Statement on Patient-Reported Outcomes in an Enhanced Recovery Pathway.

scientific article published on 29 December 2017

American Society for Enhanced Recovery and Perioperative Quality Initiative Joint Consensus Statement on Postoperative Gastrointestinal Dysfunction Within an Enhanced Recovery Pathway for Elective Colorectal Surgery

scientific article published on 29 December 2017

Antithrombin III Contributes to the Protective Effects of Fresh Frozen Plasma Following Hemorrhagic Shock by Preventing Syndecan-1 Shedding and Endothelial Barrier Disruption

scientific article published on 01 February 2020

Are all deaths recorded equally? The impact of hospice care on risk-adjusted mortality

scientific article published on 01 March 2014

Arginine decreases peroxisome proliferator-activated receptor-γ activity via c-Jun ⬇️

scientific article published on October 26, 2011

Authors’ response

Bedside ultrasound is a practical and reliable measurement tool for assessing quadriceps muscle layer thickness

scientific article published on 26 August 2013

Blood Transfusion Indicators Following Trauma in the Non-Massively Bleeding Patient

scientific article published in May 2018

Blunt abdominal aortic injury: a Western Trauma Association multicenter study

scientific article published on December 2014

Blunt cardiac injuries that require operative intervention: an unsuspected injury

scientific article published on 01 February 2003

Bone Marrow Derived Mesenchymal Stem Cells Inhibit Inflammation and Preserve Vascular Endothelial Integrity in the Lungs after Hemorrhagic Shock ⬇️

scientific article published on September 28, 2011

Both primary and secondary abdominal compartment syndrome can be predicted early and are harbingers of multiple organ failure

scientific article published in May 2003

Brief intervention by surgeons can influence students toward a career in surgery

scientific article published in May 2003

Central venous pressure versus pulmonary artery catheter-directed shock resuscitation

scientific article published in November 2009

Challenges to the care of the critically ill: novel staffing paradigms

scientific article published on 01 February 2008

Clinically Practical Approach for Screening of Low Muscularity Using Electronic Linear Measures on Computed Tomography Images in Critically Ill Patients

scientific article published on 6 December 2017

Complications of nonoperative management of high-grade blunt hepatic injuries

scientific article published in November 2005

Contemporary resuscitation of hemorrhagic shock: What will the future hold?

scientific article published on 11 May 2020

Conventional dose hypertonic saline provides optimal gut protection and limits remote organ injury after gut ischemia reperfusion

scientific article published on 01 July 2006

Cost-Utility Analysis of Levetiracetam and Phenytoin for Posttraumatic Seizure Prophylaxis ⬇️

scientific article published on August 1, 2011

Current Use of Damage-Control Laparotomy, Closure Rates, and Predictors of Early Fascial Closure at the First Take-Back ⬇️

scientific article published on June 1, 2011

Damage Control Resuscitation Is Associated With a Reduction in Resuscitation Volumes and Improvement in Survival in 390 Damage Control Laparotomy Patients ⬇️

scientific article published on October 1, 2011

Damage-control resuscitation increases successful nonoperative management rates and survival after severe blunt liver injury

scientific article published in February 2015

Defining Present Blood Component Transfusion Practices in Trauma Patients: Papers From the Trauma Outcomes Group ⬇️

scientific article published on August 1, 2011

Differential effects of luminal arginine and glutamine on metalloproteinase production in the postischemic gut.

scientific article published on July 2008

Diverse Activities of von Willebrand Factor in Traumatic Brain Injury and Associated Coagulopathy

scientific article published on 15 September 2020

Do not resuscitate status, not age, affects outcomes after injury: an evaluation of 15,227 consecutive trauma patients

scientific article published on May 2013

Dried plasma: state of the science and recent developments

scientific article published on April 2016

Driving perioperative nutrition quality improvement processes forward!

scientific article published on 01 September 2013

Early Anticoagulant Reversal After Trauma: A Western Trauma Association Critical Decisions Algorithm

scientific article published on 13 October 2020

Early cytokine production risk stratifies trauma patients for multiple organ failure.

scientific article

Early surgical intervention for blunt bowel injury: the Bowel Injury Prediction Score (BIPS).

scientific article published on January 2015

Effect of high product ratio massive transfusion on mortality in blunt and penetrating trauma patients

scientific article

Effects of poloxamer 188 on human PMN cells

scientific article published on August 2008

Enteral arginine modulates inhibition of AP-1/c-Jun by SP600125 in the postischemic gut ⬇️

scientific article published on October 29, 2010

Enteral glutamine but not alanine maintains small bowel barrier function after ischemia/reperfusion injury in rats

scientific article published in May 2004

Enteral glutamine during active shock resuscitation is safe and enhances tolerance of enteral feeding

scientific article published in January 2008

Enteral glutamine: a novel mediator of PPARgamma in the postischemic gut

scientific article published on 7 April 2008

Evaluation and management of peripheral vascular injury. Part 1. Western Trauma Association/critical decisions in trauma.

scientific article published in June 2011

Evaluation of nutrition deficits in adult and elderly trauma patients

scientific article

Existing equations to estimate lean body mass are not accurate in the critically ill: Results of a multicenter observational study

scientific article published on 23 September 2016

Extreme Dysbiosis of the Microbiome in Critical Illness

scientific article published on July 2016

Feasibility of and Rationale for the Collection of Orthopaedic Trauma Surgery Quality of Care Metrics

scientific article published on June 2017

Feeding the Postoperative Patient on Vasopressor Support: Feeding and Pressor Support

scientific article published on 24 December 2015

Fibrinogen Protects Against Barrier Dysfunction Through Maintaining Cell Surface Syndecan-1 In Vitro

scientific article published on 01 June 2019

Freeze dried platelets promote clot formation, rescue thrombin induced endothelial cell permeability, and decrease pulmonary vascular leak in a murine model of hemorrhagic shock

scientific article published on 14 October 2020

Fresh Frozen Plasma Attenuates Lung Injury in a Novel Model of Prolonged Hypotensive Resuscitation: Plasma and Prolonged Hypotensive Resuscitation

scientific article published on 08 April 2020

Fresh frozen plasma and spray-dried plasma mitigate pulmonary vascular permeability and inflammation in hemorrhagic shock

scientific article published in June 2015

Fresh frozen plasma lessens pulmonary endothelial inflammation and hyperpermeability after hemorrhagic shock and is associated with loss of syndecan 1

scientific article published on September 2013

Fresh frozen plasma should be given earlier to patients requiring massive transfusion

scientific article published in January 2007

Gastric alkalinization after major trauma

scientific article

Gastric feeding as an extension of an established enteral nutrition protocol

scientific article published on 01 October 2004

Gender-Based Differences in Mortality in Response to High Product Ratio Massive Transfusion ⬇️

scientific article published on August 1, 2011

Geriatric traumatic brain injury—What we know and what we donʼt

scientific article published on 01 October 2018

Glutamine activates peroxisome proliferator-activated receptor-γ in intestinal epithelial cells via 15-S-HETE and 13-OXO-ODE: a novel mechanism

scientific article

Glutamine protects against apoptosis via downregulation of Sp3 in intestinal epithelial cells ⬇️

scientific article published on September 30, 2010

Gunshot wounds and blast injuries to the face are associated with significant morbidity and mortality: results of an 11-year multi-institutional study of 720 patients.

scientific article

High Ratios of Plasma and Platelets to Packed Red Blood Cells Do Not Affect Mortality in Nonmassively Transfused Patients ⬇️

scientific article published on August 1, 2011

Hypertonic saline prevents inflammation, injury, and impaired intestinal transit after gut ischemia/reperfusion by inducing heme oxygenase 1 enzyme

scientific article published in April 2004

Hypertonic saline resuscitation after mesenteric ischemia/reperfusion induces ileal apoptosis

scientific article published on 01 November 2005

Hypobaria Exposure Worsens Cardiac Function and Endothelial Injury in an Animal Model of Polytrauma: Implications for Aeromedical Evacuation

scientific article published on 23 December 2020

Hypothermia hype: is it worth it?

scientific article published on May 2008

Hypothermia protects against gut ischemia/reperfusion-induced impaired intestinal transit by inducing heme oxygenase-1

scientific article published on 01 November 2003

Immune-enhancing enteral nutrients differentially modulate the early proinflammatory transcription factors mediating gut ischemia/reperfusion

scientific article

Impact of closure at the first take back: complication burden and potential overutilization of damage control laparotomy

scientific article published on December 2011

Implementation of a National Trauma Research Action Plan (NTRAP).

scientific article published on 24 January 2018

Implementation of resuscitative endovascular balloon occlusion of the aorta as an alternative to resuscitative thoracotomy for noncompressible truncal hemorrhage

scientific article

Incidence and outcome of early acute kidney injury in critically-ill trauma patients

scientific article

Increased Platelet:RBC Ratios Are Associated With Improved Survival After Massive Transfusion ⬇️

scientific article published on August 1, 2011

Increased Transforming Growth Factor β Contributes to Deterioration of Refrigerated Fresh Frozen Plasma's Effects In Vitro on Endothelial Cells ⬇️

scientific article published on July 1, 2011

Increasing age is associated with worse outcomes in elderly patients with severe liver injury

scientific article published on 02 July 2020

Inducible nitric oxide synthase mediates gut ischemia/reperfusion-induced ileus only after severe insults

scientific article

Inhibition of ERK1/2 worsens intestinal ischemia/reperfusion injury

scientific article

Injury in the aged: Geriatric trauma care at the crossroads

scientific article published on June 2015

Intestinal ischemic preconditioning after ischemia/reperfusion injury in rat intestine: profiling global gene expression patterns.

scientific article

Intraischemic hypothermia differentially modulates oxidative stress proteins during mesenteric ischemia/reperfusion

scientific article published in August 2002

Intraluminal tranexamic acid inhibits intestinal sheddases and mitigates gut and lung injury and inflammation in a rodent model of hemorrhagic shock

scientific article

Introduction: Olga M. Jonasson, MD, Lecture

scientific article published in February 2017

Is Tranexamic Acid Associated With Mortality or Multiple Organ Failure Following Severe Injury?

scientific article published on 01 January 2021

Is all plasma created equal? A pilot study of the effect of interdonor variability

scientific article published on 01 January 2020

Is low-molecular-weight heparin safe for venous thromboembolism prophylaxis in patients with traumatic brain injury? A Western Trauma Association multicenter study ⬇️

scientific article published on September 1, 2012

Ischemic preconditioning protects against gut dysfunction and mucosal injury after ischemia/reperfusion injury

scientific article published on 01 March 2005

Lack of species-specific difference in pulmonary function when using mouse versus human plasma in a mouse model of hemorrhagic shock

scientific article published in November 2016

Laparoscopic repair of traumatic diaphragmatic injuries

scientific article

Loss of Syndecan-1 Abrogates the Pulmonary Protective Phenotype Induced by Plasma After Hemorrhagic Shock.

scientific article published on 19 January 2017

Lyophilized plasma attenuates vascular permeability, inflammation and lung injury in hemorrhagic shock.

scientific article

Management of adult blunt hepatic trauma ⬇️

scientific article published on December 1, 2010

Massive transfusion policies at trauma centers participating in the American College of Surgeons Trauma Quality Improvement Program.

scientific article

Mesenchymal stem cells regulate blood-brain barrier integrity through TIMP3 release after traumatic brain injury

scientific article published on November 2012

Microvesicle phenotypes are associated with transfusion requirements and mortality in subjects with severe injuries

scientific article

Migrating Motility Complexes Persist after Severe Traumatic Shock in Patients Who Tolerate Enteral Nutrition ⬇️

scientific article published on December 1, 2001

Modulation of syndecan-1 shedding after hemorrhagic shock and resuscitation.

scientific article

Molecular mechanisms of pharmaconutrients

scientific article published on 17 July 2009

Morbidity from Rib Fractures Increases After Age 45 ⬇️

scientific article published on April 1, 2003

Multiple levels of degradation diminish hemostatic potential of thawed plasma

scientific article

Multitargeted Feeding Strategies Improve Nutrition Outcome and Are Associated With Reduced Pneumonia in a Level 1 Trauma Intensive Care Unit

scientific article published in March 2017

Natural history of splenic vascular abnormalities after blunt injury: A Western Trauma Association multicenter trial

scientific article published on 30 May 2017

Nontrauma open abdomens: A prospective observational study

scientific article published on 21 January 2016

Normal versus supranormal oxygen delivery goals in shock resuscitation: the response is the same

scientific article published in November 2002

Nutrition in the critically ill surgical patient

scientific article published on 29 September 2020

Nutrition support in adult trauma patients

scientific article published on October 2006

Organ injury scaling 2018 update: Spleen, liver, and kidney

scientific article published on 01 December 2018

Patients with impending abdominal compartment syndrome do not respond to early volume loading

scientific article

Peroxisome proliferator-activated receptor gamma mediates protection against cyclooxygenase-2-induced gut dysfunction in a rodent model of mesenteric ischemia/reperfusion

scientific journal article

Pharmaconutrition review: physiological mechanisms

scientific article published on September 2013

Plasma for burn shock resuscitation: is it time to go back to the future?

scientific article published on 01 April 2019

Plasma restoration of endothelial glycocalyx in a rodent model of hemorrhagic shock

scientific article

Plasma-Mediated Gut Protection After Hemorrhagic Shock is Lessened in Syndecan-1-/- Mice.

scientific article published on 10 August 2015

Poloxamer 188 inhibition of ischemia/reperfusion injury: evidence for a novel anti-adhesive mechanism

scientific article published on 01 January 2010

Position statement of the American College of Surgeons Committee on Trauma on the National Academies of Sciences, Engineering and Medicine Report, A National Trauma Care System: Integrating Military and Civilian Trauma Systems to Achieve Zero Preven

scientific article published on 16 August 2016

Postinjury Primary Abdominal Compartment Syndrome

scientific article published on 30 July 2008

Postinjury enteral tolerance is reliably achieved by a standardized protocol

scientific article published on 01 May 2002

Potential targets to encourage a surgical career

scientific article

Preclinical predictors of surgery NBME exam performance

scientific article published on June 2007

Preclinical students: who are surgeons?

scientific article published on 01 June 2004

Prehospital resuscitation in adult patients following injury: A Western Trauma Association critical decisions algorithm

scientific article published on 01 November 2019

Preload optimization using "starling curve" generation during shock resuscitation: can it be done?

scientific article published in April 2004

Profoundly abnormal initial physiologic and biochemical data cannot be used to determine futility in massively transfused trauma patients.

scientific article

Protection by enteral glutamine is mediated by intestinal epithelial cell peroxisome proliferator-activated receptor-γ during intestinal ischemia/reperfusion

scientific article

Protective Role of p70S6K in Intestinal Ischemia/Reperfusion Injury in Mice ⬇️

scientific article published on July 27, 2012

Protective effects of fresh frozen plasma on vascular endothelial permeability, coagulation, and resuscitation after hemorrhagic shock are time dependent and diminish between days 0 and 5 after thaw

scientific article published on July 2010

Rapid Thrombelastography Delivers Real-Time Results That Predict Transfusion Within 1 Hour of Admission ⬇️

scientific article published on August 1, 2011

Re: ADAM-17: A potential therapeutic target to prevent organ injury after hemorrhagic shock?

scientific article

Reply to Letter: Organ injury scaling 2018 update: Spleen, liver, and kidney

scientific article published on 01 October 2019

Resuscitative Strategies to Modulate the Endotheliopathy of Trauma: From Cell to Patient

scientific article published on 10 May 2019

Risk factors for hepatic morbidity following nonoperative management: multicenter study

scientific article

Role of anabolic testosterone agents and structured exercise to promote recovery in ICU survivors

scientific article published on 06 August 2020

Role of level IV trauma centers in an inclusive trauma system: the injured elderly

scientific article

Role of von Willebrand Factor after Injury: It may do More than we Think

scientific article published on 04 November 2020

Secondary abdominal compartment syndrome is an elusive early complication of traumatic shock resuscitation

scientific article

Skeletal muscle predicts ventilator-free days, ICU-free days, and mortality in elderly ICU patients

scientific article

Solitary Blunt Rupture of an Accessory Spleen ⬇️

scientific article published on 01 January 1998

Specific abbreviated injury scale values are responsible for the underestimation of mortality in penetrating trauma patients by the injury severity score

scientific article published in August 2011

Specific intraluminal nutrients alter mucosal blood flow during gut ischemia/reperfusion

scientific article

Standardized trauma resuscitation: female hearts respond better

scientific article

Summary points and consensus recommendations from the North American Surgical Nutrition Summit

scientific article published on 01 September 2013

Superior mesenteric artery occlusion models shock-induced gut ischemia-reperfusion

scientific article published in January 2004

Supranormal trauma resuscitation causes more cases of abdominal compartment syndrome

scientific article published on 01 June 2003

Surgical education research

scientific article published on 02 September 2005

Syndecan 1 Plays a Novel Role in Enteral Glutamine’s Gut-Protective Effects of the Postischemic Gut ⬇️

scientific article published on July 1, 2012

Syndecan-1 limits the progression of liver injury and promotes liver repair in acetaminophen-induced liver injury in mice

scientific article published on 22 May 2017

Syndecan-1 restitution by plasma after hemorrhagic shock

scientific article published on June 2015

The American Association for the Surgery of Trauma Renal Grading System: Should Segmental Kidney Infarction be Classified as a Grade IV Injury?

scientific article published on 10 July 2020

The Coalition for National Trauma Research (CNTR) Supports the Call for a National Trauma Research Action Plan

scientific article published on 23 December 2016

The association between Chance fractures and intra-abdominal injuries revisited: a multicenter review

scientific article

The association of blood component use ratios with the survival of massively transfused trauma patients with and without severe brain injury

scientific article published in August 2011

The changing face of surgical education: simulation as the new paradigm

scientific article

The immune-enhancing enteral agents arginine and glutamine differentially modulate gut barrier function following mesenteric ischemia/reperfusion

scientific article published in December 2004

The role of computed tomographic scan in ongoing triage of operative hepatic trauma: A Western Trauma Association multicenter retrospective study

scientific article published on 02 September 2015

The splenic injury outcomes trial: An American Association for the Surgery of Trauma multi-institutional study

scientific article published on September 2015

The surgically induced stress response

scientific article published on September 2013

The type of sodium-coupled solute modulates small bowel mucosal injury, transport function, and ATP after ischemia/reperfusion injury in rats

scientific article published in September 2002

Thrombin Generation Kinetics are Predictive of Rapid Transfusion in Trauma Patients Meeting Critical Administration Threshold

scientific article published on 20 August 2020

Training future surgical scientists: realities and recommendations

scientific article published on May 2008

Transitions of Care in Geriatric Medicine

scientific article published on 03 October 2018

Trauma hemostasis and oxygenation research position paper on remote damage control resuscitation: definitions, current practice, and knowledge gaps

scientific article

Traumatic hematuria in patients with polycystic kidney disease.

scientific article

Underappreciation of sleep disorders as a cause of motor vehicle crashes ⬇️

scientific article published on November 1, 2001

Unique pattern of complications in elderly trauma patients at a Level I trauma center ⬇️

scientific article published on January 1, 2012

Update on postinjury nutrition

scientific article published on December 2008

Updated Guidelines to Reduce Venous Thromboembolism in Trauma Patients: A Western Trauma Association Critical Decisions Algorithm

scientific article published on 24 June 2020

Vacuum-assisted wound closure achieves early fascial closure of open abdomens after severe trauma

scientific article published on December 2003

Vacuum-assisted wound closure provides early fascial reapproximation in trauma patients with open abdomens

scientific article published in December 2001

Validation of Bedside Ultrasound of Muscle Layer Thickness of the Quadriceps in the Critically Ill Patient (VALIDUM Study).

scientific article published on 9 March 2016

Variations Between Level I Trauma Centers in 24-Hour Mortality in Severely Injured Patients Requiring a Massive Transfusion ⬇️

scientific article published on August 1, 2011

Western Trauma Association critical decisions in trauma: nonoperative management of adult blunt hepatic trauma

scientific article published on December 2009

Western Trauma Association critical decisions in trauma: screening for and treatment of blunt cerebrovascular injuries.

scientific article published on December 2009

Western Trauma Association/critical decisions in trauma: operative management of adult blunt hepatic trauma.

scientific article published on July 2011

What'S New in SHOCK, AUGUST 2017?

scientific article published in August 2017

What's New in Shock, September 2019?

scientific article published on 01 September 2019

What's new in Shock, December 2014?

scientific article published on 01 December 2014

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