List of works - Assunta Lombardi

3,5 Diiodo-l-Thyronine (T₂) Promotes the Browning of White Adipose Tissue in High-Fat Diet-Induced Overweight Male Rats Housed at Thermoneutrality

scientific article published on 18 March 2019

3,5-Diiodo- l -thyronine and 3,5,3′-triiodo- l -thyronine both improve the cold tolerance of hypothyroid rats, but possibly via different mechanisms ⬇️

scientific article published on August 1, 1998

3,5-Diiodo-L-Thyronine Affects Structural and Metabolic Features of Skeletal Muscle Mitochondria in High-Fat-Diet Fed Rats Producing a Co-adaptation to the Glycolytic Fiber Phenotype

scientific article published on 9 March 2018

3,5-Diiodo-L-Thyronine Exerts Metabolically Favorable Effects on Visceral Adipose Tissue of Rats Receiving a High-Fat Diet

scientific article published on 27 January 2019

3,5-Diiodo-L-thyronine activates brown adipose tissue thermogenesis in hypothyroid rats

scientific article published in 2015

3,5-Diiodo-L-thyronine prevents high-fat-diet-induced insulin resistance in rat skeletal muscle through metabolic and structural adaptations.

scientific article

3,5-diiodo-L-thyronine powerfully reduces adiposity in rats by increasing the burning of fats.

scientific article

3,5-diiodo-l-thyronine, by modulating mitochondrial functions, reverses hepatic fat accumulation in rats fed a high-fat diet.

scientific article published on 3 May 2009

A proteomics approach to identify protein expression changes in rat liver following administration of 3,5,3'-triiodo-L-thyronine.

scientific article

Absence of Uncoupling Protein-3 at Thermoneutrality Impacts Lipid Handling and Energy Homeostasis in Mice

scientific article published on 17 August 2019

Absence of uncoupling protein 3 at thermoneutrality influences brown adipose tissue mitochondrial functionality in mice

scientific article published on 18 September 2020

Acute administration of 3,5-diiodo-L-thyronine to hypothyroid rats affects bioenergetic parameters in rat skeletal muscle mitochondria.

scientific article published on 3 December 2007

Age-related changes in renal and hepatic cellular mechanisms associated with variations in rat serum thyroid hormone levels.

scientific article published on 22 April 2008

Akap1 Deficiency Promotes Mitochondrial Aberrations and Exacerbates Cardiac Injury Following Permanent Coronary Ligation via Enhanced Mitophagy and Apoptosis

scientific article

Are the effects of T3 on resting metabolic rate in euthyroid rats entirely caused by T3 itself?

scientific article published in February 2002

BN-PAGE-based approach to study thyroid hormones and mitochondrial function

scientific article published in January 2015

Both 3,3',5-triiodothyronine and 3,5-diodo-L-thyronine Are Able to Repair Mitochondrial DNA Damage but by Different Mechanisms

Both 3,5-Diiodo-L-Thyronine and 3,5,3'-Triiodo-L-Thyronine Prevent Short-term Hepatic Lipid Accumulation via Distinct Mechanisms in Rats Being Fed a High-Fat Diet

scientific article published on 14 September 2017

Characterization of the binding of 3,3′-di-iodo-l-thyronine to rat liver mitochondria ⬇️

scientific article published on 01 July 1997

Combined cDNA array/RT-PCR analysis of gene expression profile in rat gastrocnemius muscle: relation to its adaptive function in energy metabolism during fasting

scientific journal article

Correction: Akap1 Deficiency Promotes Mitochondrial Aberrations and Exacerbates Cardiac Injury Following Permanent Coronary Ligation via Enhanced Mitophagy and Apoptosis

scientific article published on 6 July 2016

Differential 3,5,3'-triiodothyronine-mediated regulation of uncoupling protein 3 transcription: role of Fatty acids

scientific journal article

Differential Effects of 3,5-Diiodo-L-Thyronine and 3,5,3'-Triiodo-L-Thyronine On Mitochondrial Respiratory Pathways in Liver from Hypothyroid Rats

scientific article published on 10 July 2018

Editorial: Insights Into Brown Adipose Tissue Functions and Browning Phenomenon

scientific article published on 06 March 2020

Effect of 3,5-di-iodo-L-thyronine on the mitochondrial energy-transduction apparatus ⬇️

scientific article published on February 15, 1998

Effect of Iodothyronines on Thermogenesis: Focus on Brown Adipose Tissue.

scientific article

Exercise with food withdrawal at thermoneutrality impacts fuel use, the microbiome, AMPK phosphorylation, muscle fibers, and thyroid hormone levels in rats

scientific article published on 01 February 2020

Fasting, lipid metabolism, and triiodothyronine in rat gastrocnemius muscle: interrelated roles of uncoupling protein 3, mitochondrial thioesterase, and coenzyme Q ⬇️

scientific article published on April 8, 2003

Fenofibrate activates the biochemical pathways and the de novo expression of genes related to lipid handling and uncoupling protein-3 functions in liver of normal rats

scientific journal article

Fuel economy in food-deprived skeletal muscle: signaling pathways and regulatory mechanisms.

scientific article published on 26 June 2007

Genetic deletion of uncoupling protein 3 exaggerates apoptotic cell death in the ischemic heart leading to heart failure.

scientific article published on 20 May 2013

Identification of 3,5-Diiodo-l-Thyronine-Binding Proteins in Rat Liver Cytosol by Photoaffinity Labeling ⬇️

scientific article published on June 1, 2003

Interrelated influence of superoxides and free fatty acids over mitochondrial uncoupling in skeletal muscle.

scientific article published on 18 April 2008

Loss of Akap1 Exacerbates Pressure Overload-Induced Cardiac Hypertrophy and Heart Failure.

scientific article

Metabolic effects of the iodothyronine functional analogue TRC150094 on the liver and skeletal muscle of high-fat diet fed overweight rats: an integrated proteomic study.

scientific article published on 27 April 2012

Metabolic effects of thyroid hormone derivatives.

scientific article published on February 2008

Nonthyrotoxic prevention of diet-induced insulin resistance by 3,5-diiodo-L-thyronine in rats.

scientific article

PPARs: Nuclear Receptors Controlled by, and Controlling, Nutrient Handling through Nuclear and Cytosolic Signaling ⬇️

scientific article published on January 1, 2010

Pathways affected by 3,5-diiodo-l-thyronine in liver of high fat-fed rats: evidence from two-dimensional electrophoresis, blue-native PAGE, and mass spectrometry

scientific article published on 16 September 2010

Peroxisome Proliferator-Activated Receptor Delta: A Conserved Director of Lipid Homeostasis through Regulation of the Oxidative Capacity of Muscle

scientific article published on January 2008

Rapid activation by 3,5,3'-L-triiodothyronine of adenosine 5'-monophosphate-activated protein kinase/acetyl-coenzyme a carboxylase and akt/protein kinase B signaling pathways: relation to changes in fuel metabolism and myosin heavy-chain protein con

scientific article published on 14 August 2008

Regulation of skeletal muscle mitochondrial activity by thyroid hormones: focus on the "old" triiodothyronine and the "emerging" 3,5-diiodothyronine

scientific article

Responses of skeletal muscle lipid metabolism in rat gastrocnemius to hypothyroidism and iodothyronine administration: a putative role for FAT/CD36.

scientific article published on 11 September 2012

Sequential changes in the signal transduction responses of skeletal muscle following food deprivation

scientific article published on 25 October 2006

Studies of complex biological systems with applications to molecular medicine: the need to integrate transcriptomic and proteomic approaches

scientific article

TRC150094, a novel functional analog of iodothyronines, reduces adiposity by increasing energy expenditure and fatty acid oxidation in rats receiving a high-fat diet

scientific article published on 7 May 2010

The saturation degree of fatty acids and their derived acylcarnitines determines the direct effect of metabolically active thyroid hormones on insulin sensitivity in skeletal muscle cells

scientific article published on 11 September 2018

Thyroid-state influence on protein-expression profile of rat skeletal muscle

scientific article

UCP3 translocates lipid hydroperoxide and mediates lipid hydroperoxide-dependent mitochondrial uncoupling.

scientific article

Uncoupling protein 3 expression levels influence insulin sensitivity, fatty acid oxidation, and related signaling pathways.

scientific article

Uncoupling proteins: a complex journey to function discovery.

scientific article published on September 2009

List of works by Assunta Lombardi

3,5 Diiodo-l-Thyronine (T₂) Promotes the Browning of White Adipose Tissue in High-Fat Diet-Induced Overweight Male Rats Housed at Thermoneutrality

3,5-Diiodo- l -thyronine and 3,5,3′-triiodo- l -thyronine both improve the cold tolerance of hypothyroid rats, but possibly via different mechanisms ⬇️

3,5-Diiodo-L-Thyronine Affects Structural and Metabolic Features of Skeletal Muscle Mitochondria in High-Fat-Diet Fed Rats Producing a Co-adaptation to the Glycolytic Fiber Phenotype

3,5-Diiodo-L-Thyronine Exerts Metabolically Favorable Effects on Visceral Adipose Tissue of Rats Receiving a High-Fat Diet

3,5-Diiodo-L-thyronine activates brown adipose tissue thermogenesis in hypothyroid rats

3,5-Diiodo-L-thyronine prevents high-fat-diet-induced insulin resistance in rat skeletal muscle through metabolic and structural adaptations.

3,5-diiodo-L-thyronine powerfully reduces adiposity in rats by increasing the burning of fats.

3,5-diiodo-l-thyronine, by modulating mitochondrial functions, reverses hepatic fat accumulation in rats fed a high-fat diet.

A proteomics approach to identify protein expression changes in rat liver following administration of 3,5,3'-triiodo-L-thyronine.

Absence of Uncoupling Protein-3 at Thermoneutrality Impacts Lipid Handling and Energy Homeostasis in Mice

Absence of uncoupling protein 3 at thermoneutrality influences brown adipose tissue mitochondrial functionality in mice

Acute administration of 3,5-diiodo-L-thyronine to hypothyroid rats affects bioenergetic parameters in rat skeletal muscle mitochondria.

Age-related changes in renal and hepatic cellular mechanisms associated with variations in rat serum thyroid hormone levels.

Akap1 Deficiency Promotes Mitochondrial Aberrations and Exacerbates Cardiac Injury Following Permanent Coronary Ligation via Enhanced Mitophagy and Apoptosis

Are the effects of T3 on resting metabolic rate in euthyroid rats entirely caused by T3 itself?

BN-PAGE-based approach to study thyroid hormones and mitochondrial function

Both 3,3',5-triiodothyronine and 3,5-diodo-L-thyronine Are Able to Repair Mitochondrial DNA Damage but by Different Mechanisms

Both 3,5-Diiodo-L-Thyronine and 3,5,3'-Triiodo-L-Thyronine Prevent Short-term Hepatic Lipid Accumulation via Distinct Mechanisms in Rats Being Fed a High-Fat Diet

Characterization of the binding of 3,3′-di-iodo-l-thyronine to rat liver mitochondria ⬇️

Combined cDNA array/RT-PCR analysis of gene expression profile in rat gastrocnemius muscle: relation to its adaptive function in energy metabolism during fasting

Correction: Akap1 Deficiency Promotes Mitochondrial Aberrations and Exacerbates Cardiac Injury Following Permanent Coronary Ligation via Enhanced Mitophagy and Apoptosis

Differential 3,5,3'-triiodothyronine-mediated regulation of uncoupling protein 3 transcription: role of Fatty acids

Differential Effects of 3,5-Diiodo-L-Thyronine and 3,5,3'-Triiodo-L-Thyronine On Mitochondrial Respiratory Pathways in Liver from Hypothyroid Rats

Editorial: Insights Into Brown Adipose Tissue Functions and Browning Phenomenon

Effect of 3,5-di-iodo-L-thyronine on the mitochondrial energy-transduction apparatus ⬇️

Effect of Iodothyronines on Thermogenesis: Focus on Brown Adipose Tissue.

Exercise with food withdrawal at thermoneutrality impacts fuel use, the microbiome, AMPK phosphorylation, muscle fibers, and thyroid hormone levels in rats

Fasting, lipid metabolism, and triiodothyronine in rat gastrocnemius muscle: interrelated roles of uncoupling protein 3, mitochondrial thioesterase, and coenzyme Q ⬇️

Fenofibrate activates the biochemical pathways and the de novo expression of genes related to lipid handling and uncoupling protein-3 functions in liver of normal rats

Fuel economy in food-deprived skeletal muscle: signaling pathways and regulatory mechanisms.

Genetic deletion of uncoupling protein 3 exaggerates apoptotic cell death in the ischemic heart leading to heart failure.

Identification of 3,5-Diiodo-l-Thyronine-Binding Proteins in Rat Liver Cytosol by Photoaffinity Labeling ⬇️

Interrelated influence of superoxides and free fatty acids over mitochondrial uncoupling in skeletal muscle.

Loss of Akap1 Exacerbates Pressure Overload-Induced Cardiac Hypertrophy and Heart Failure.

Metabolic effects of the iodothyronine functional analogue TRC150094 on the liver and skeletal muscle of high-fat diet fed overweight rats: an integrated proteomic study.

Metabolic effects of thyroid hormone derivatives.

Nonthyrotoxic prevention of diet-induced insulin resistance by 3,5-diiodo-L-thyronine in rats.

PPARs: Nuclear Receptors Controlled by, and Controlling, Nutrient Handling through Nuclear and Cytosolic Signaling ⬇️

Pathways affected by 3,5-diiodo-l-thyronine in liver of high fat-fed rats: evidence from two-dimensional electrophoresis, blue-native PAGE, and mass spectrometry

Peroxisome Proliferator-Activated Receptor Delta: A Conserved Director of Lipid Homeostasis through Regulation of the Oxidative Capacity of Muscle

Rapid activation by 3,5,3'-L-triiodothyronine of adenosine 5'-monophosphate-activated protein kinase/acetyl-coenzyme a carboxylase and akt/protein kinase B signaling pathways: relation to changes in fuel metabolism and myosin heavy-chain protein con

Regulation of skeletal muscle mitochondrial activity by thyroid hormones: focus on the "old" triiodothyronine and the "emerging" 3,5-diiodothyronine

Responses of skeletal muscle lipid metabolism in rat gastrocnemius to hypothyroidism and iodothyronine administration: a putative role for FAT/CD36.

Sequential changes in the signal transduction responses of skeletal muscle following food deprivation

Studies of complex biological systems with applications to molecular medicine: the need to integrate transcriptomic and proteomic approaches

TRC150094, a novel functional analog of iodothyronines, reduces adiposity by increasing energy expenditure and fatty acid oxidation in rats receiving a high-fat diet

The saturation degree of fatty acids and their derived acylcarnitines determines the direct effect of metabolically active thyroid hormones on insulin sensitivity in skeletal muscle cells

Thyroid-state influence on protein-expression profile of rat skeletal muscle

UCP3 translocates lipid hydroperoxide and mediates lipid hydroperoxide-dependent mitochondrial uncoupling.

Uncoupling protein 3 expression levels influence insulin sensitivity, fatty acid oxidation, and related signaling pathways.

Uncoupling proteins: a complex journey to function discovery.