List of works - Magnus Abrink

A key role for mast cell chymase in the activation of pro-matrix metalloprotease-9 and pro-matrix metalloprotease-2.

scientific article published on 22 December 2004

A novel Krüppel-Associated Box identified in a panel of mammalian zinc finger proteins

scientific article published in January 2004

A role for serglycin proteoglycan in granular retention and processing of mast cell secretory granule components

scientific journal article

Age-related enlargement of lymphoid tissue and altered leukocyte composition in serglycin-deficient mice

article

Bcl-2 and Bcl-XL are indispensable for the late phase of mast cell development from mouse embryonic stem cells

scientific article published on 01 March 2007

Cooperation between mast cell carboxypeptidase A and the chymase mouse mast cell protease 4 in the formation and degradation of angiotensin II

scientific journal article

Critical role of mast cell chymase in mouse abdominal aortic aneurysm formation

scientific article published on 31 August 2009

Delayed contraction of the CD8+ T cell response toward lymphocytic choriomeningitis virus infection in mice lacking serglycin

scientific journal article

Dual targets for mouse mast cell protease-4 in mediating tissue damage in experimental bullous pemphigoid

scientific article

Generation and characterization of a Gdf1 conditional null allele

scientific article

IGF-1 degradation by mouse mast cell protease 4 promotes cell death and adverse cardiac remodeling days after a myocardial infarction

scientific article published on 06 June 2016

Independent degeneration of photoreceptors and retinal pigment epithelium in conditional knockout mouse models of choroideremia

scientific article

KRAB zinc finger proteins: an analysis of the molecular mechanisms governing their increase in numbers and complexity during evolution

scientific article published on December 2002

Loss of Bladder Epithelium Induced by Cytolytic Mast Cell Granules.

scientific article published on 25 November 2016

Loss of Serglycin Promotes Primary Tumor Growth and Vessel Functionality in the RIP1-Tag2 Mouse Model for Spontaneous Insulinoma Formation

scientific article published on 15 May 2015

Lowered Expression of Heparan Sulfate/Heparin Biosynthesis Enzyme N-Deacetylase/N-Sulfotransferase 1 Results in Increased Sulfation of Mast Cell Heparin ⬇️

scientific article published on November 2, 2011

MZF6D, a novel KRAB zinc-finger gene expressed exclusively in meiotic male germ cells

scientific article published on 01 August 2003

Mast Cell Chymase Decreases The Severity Of Group B Streptococcus Infections

scientific article published on 12 September 2017

Mast cell chymase contributes to the antibody response and the severity of autoimmune arthritis

scientific article

Mast cell chymase protects against acute ischemic kidney injury by limiting neutrophil hyperactivation and recruitment

scientific article published on 10 October 2019

Mast cell chymase reduces the toxicity of Gila monster venom, scorpion venom, and vasoactive intestinal polypeptide in mice

scientific article

Mast cell proteases

scientific article published on January 2007

Mast cell-dependent activation of pro matrix metalloprotease 2: A role for serglycin proteoglycan-dependent mast cell proteases

scientific journal article

Mast cells can enhance resistance to snake and honeybee venoms

scientific article

Mast cells contribute to bleomycin-induced lung inflammation and injury in mice through a chymase/mast cell protease 4-dependent mechanism

scientific article published on 22 January 2014

Mast cells regulate homeostatic intestinal epithelial migration and barrier function by a chymase/Mcpt4-dependent mechanism

scientific article

Mouse mast cell protease 4 is the major chymase in murine airways and has a protective role in allergic airway inflammation

scientific article published on 19 October 2009

Mouse mast cell protease-4 deteriorates renal function by contributing to inflammation and fibrosis in immune complex-mediated glomerulonephritis

scientific article

Neurotensin increases mortality and mast cells reduce neurotensin levels in a mouse model of sepsis

scientific article

Neutrophil elastase depends on serglycin proteoglycan for localization in granules

scientific article published on 01 February 2007

Proteome analysis of mast cell releasates reveals a role for chymase in the regulation of coagulation factor XIIIA levels via proteolytic degradation.

scientific article published on 13 May 2016

Rab27b regulates mast cell granule dynamics and secretion

scientific article

Rab27b regulates number and secretion of platelet dense granules

scholarly article

Reduction with dithiothreitol causes serglycin-specific defects in secretory granule integrity of bone marrow derived mast cells

scientific article published on 6 December 2008

Serglycin is essential for maturation of mast cell secretory granule

scientific journal article

Serglycin is the major secreted proteoglycan in macrophages and has a role in the regulation of macrophage tumor necrosis factor-alpha secretion in response to lipopolysaccharide

scientific journal article

Serglycin proteoglycan deletion induces defects in platelet aggregation and thrombus formation in mice

scientific article published on 19 December 2007

Serglycin proteoglycan is not implicated in localizing exocrine pancreas enzymes to zymogen granules.

scientific article published on 14 May 2009

Serglycin proteoglycan is required for secretory granule integrity in mucosal mast cells

scientific article published on April 2007

Serglycin proteoglycan: regulating the storage and activities of hematopoietic proteases

scientific article published on January 2009

Serglycin-deficient cytotoxic T lymphocytes display defective secretory granule maturation and granzyme B storage

scientific journal article

Serotonin and histamine storage in mast cell secretory granules is dependent on serglycin proteoglycan

scientific article published on 30 January 2008

Targeted disruption of a murine glucuronyl C5-epimerase gene results in heparan sulfate lacking L-iduronic acid and in neonatal lethality

scientific journal article

The 5'-AMP-activated protein kinase gamma3 isoform has a key role in carbohydrate and lipid metabolism in glycolytic skeletal muscle

scientific article

The chymase mouse mast cell protease 4 degrades TNF, limits inflammation, and promotes survival in a model of sepsis

scientific article

The chymase, mouse mast cell protease 4, constitutes the major chymotrypsin-like activity in peritoneum and ear tissue. A role for mouse mast cell protease 4 in thrombin regulation and fibronectin turnover

scientific journal article

The inflammatory response after an epidermal burn depends on the activities of mouse mast cell proteases 4 and 5.

scientific article

The αvβ6 integrin modulates airway hyperresponsiveness in mice by regulating intraepithelial mast cells.

scientific article published on 9 January 2012

Vaccination against the extra domain-B of fibronectin as a novel tumor therapy.

scientific article published on 15 July 2010

List of works by Magnus Abrink

A key role for mast cell chymase in the activation of pro-matrix metalloprotease-9 and pro-matrix metalloprotease-2.

A novel Krüppel-Associated Box identified in a panel of mammalian zinc finger proteins

A role for serglycin proteoglycan in granular retention and processing of mast cell secretory granule components

Age-related enlargement of lymphoid tissue and altered leukocyte composition in serglycin-deficient mice

Bcl-2 and Bcl-XL are indispensable for the late phase of mast cell development from mouse embryonic stem cells

Cooperation between mast cell carboxypeptidase A and the chymase mouse mast cell protease 4 in the formation and degradation of angiotensin II

Critical role of mast cell chymase in mouse abdominal aortic aneurysm formation

Delayed contraction of the CD8+ T cell response toward lymphocytic choriomeningitis virus infection in mice lacking serglycin

Dual targets for mouse mast cell protease-4 in mediating tissue damage in experimental bullous pemphigoid

Generation and characterization of a Gdf1 conditional null allele

IGF-1 degradation by mouse mast cell protease 4 promotes cell death and adverse cardiac remodeling days after a myocardial infarction

Independent degeneration of photoreceptors and retinal pigment epithelium in conditional knockout mouse models of choroideremia

KRAB zinc finger proteins: an analysis of the molecular mechanisms governing their increase in numbers and complexity during evolution

Loss of Bladder Epithelium Induced by Cytolytic Mast Cell Granules.

Loss of Serglycin Promotes Primary Tumor Growth and Vessel Functionality in the RIP1-Tag2 Mouse Model for Spontaneous Insulinoma Formation

Lowered Expression of Heparan Sulfate/Heparin Biosynthesis Enzyme N-Deacetylase/N-Sulfotransferase 1 Results in Increased Sulfation of Mast Cell Heparin ⬇️

MZF6D, a novel KRAB zinc-finger gene expressed exclusively in meiotic male germ cells

Mast Cell Chymase Decreases The Severity Of Group B Streptococcus Infections

Mast cell chymase contributes to the antibody response and the severity of autoimmune arthritis

Mast cell chymase protects against acute ischemic kidney injury by limiting neutrophil hyperactivation and recruitment

Mast cell chymase reduces the toxicity of Gila monster venom, scorpion venom, and vasoactive intestinal polypeptide in mice

Mast cell proteases

Mast cell-dependent activation of pro matrix metalloprotease 2: A role for serglycin proteoglycan-dependent mast cell proteases

Mast cells can enhance resistance to snake and honeybee venoms

Mast cells contribute to bleomycin-induced lung inflammation and injury in mice through a chymase/mast cell protease 4-dependent mechanism

Mast cells regulate homeostatic intestinal epithelial migration and barrier function by a chymase/Mcpt4-dependent mechanism

Mouse mast cell protease 4 is the major chymase in murine airways and has a protective role in allergic airway inflammation

Mouse mast cell protease-4 deteriorates renal function by contributing to inflammation and fibrosis in immune complex-mediated glomerulonephritis

Neurotensin increases mortality and mast cells reduce neurotensin levels in a mouse model of sepsis

Neutrophil elastase depends on serglycin proteoglycan for localization in granules

Proteome analysis of mast cell releasates reveals a role for chymase in the regulation of coagulation factor XIIIA levels via proteolytic degradation.

Rab27b regulates mast cell granule dynamics and secretion

Rab27b regulates number and secretion of platelet dense granules

Reduction with dithiothreitol causes serglycin-specific defects in secretory granule integrity of bone marrow derived mast cells

Serglycin is essential for maturation of mast cell secretory granule

Serglycin is the major secreted proteoglycan in macrophages and has a role in the regulation of macrophage tumor necrosis factor-alpha secretion in response to lipopolysaccharide

Serglycin proteoglycan deletion induces defects in platelet aggregation and thrombus formation in mice

Serglycin proteoglycan is not implicated in localizing exocrine pancreas enzymes to zymogen granules.

Serglycin proteoglycan is required for secretory granule integrity in mucosal mast cells

Serglycin proteoglycan: regulating the storage and activities of hematopoietic proteases

Serglycin-deficient cytotoxic T lymphocytes display defective secretory granule maturation and granzyme B storage

Serotonin and histamine storage in mast cell secretory granules is dependent on serglycin proteoglycan

Targeted disruption of a murine glucuronyl C5-epimerase gene results in heparan sulfate lacking L-iduronic acid and in neonatal lethality

The 5'-AMP-activated protein kinase gamma3 isoform has a key role in carbohydrate and lipid metabolism in glycolytic skeletal muscle

The chymase mouse mast cell protease 4 degrades TNF, limits inflammation, and promotes survival in a model of sepsis

The chymase, mouse mast cell protease 4, constitutes the major chymotrypsin-like activity in peritoneum and ear tissue. A role for mouse mast cell protease 4 in thrombin regulation and fibronectin turnover

The inflammatory response after an epidermal burn depends on the activities of mouse mast cell proteases 4 and 5.

The αvβ6 integrin modulates airway hyperresponsiveness in mice by regulating intraepithelial mast cells.

Vaccination against the extra domain-B of fibronectin as a novel tumor therapy.