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List of works by Kurt R. Klimpel

Anthrax toxin lethal factor contains a zinc metalloprotease consensus sequence which is required for lethal toxin activity

scientific journal article

Anthrax toxin mechanisms of receptor binding and internalization

Anthrax toxin protective antigen is activated by a cell surface protease with the sequence specificity and catalytic properties of furin

scientific article published on November 1, 1992

Cell walls from avirulent variants of Histoplasma capsulatum lack alpha-(1,3)-glucan

scientific article

Characterization of lethal factor binding and cell receptor binding domains of protective antigen of Bacillus anthracis using monoclonal antibodies

scientific article published on 01 March 1996

Cloning and characterization of a gene whose product is a trans-activator of anthrax toxin synthesis

scientific article

Crystal structure of the anthrax toxin protective antigen

scientific article

Delivery of Antigens to the MHC Class I Pathway Using Bacterial Toxins

scientific article published on May 1, 1997

Detection and quantification of infectious hypodermal and hematopoietic necrosis virus and white spot virus in shrimp using real-time quantitative PCR and SYBR Green chemistry

scientific article

Functional mapping of anthrax toxin lethal factor by in-frame insertion mutagenesis.

scientific article published on October 1991

Fusions of anthrax toxin lethal factor to the ADP-ribosylation domain of Pseudomonas exotoxin A are potent cytotoxins which are translocated to the cytosol of mammalian cells

scientific article published on August 1992

Genetic variation and immunohistochemical differences among geographic isolates of Taura syndrome virus of penaeid shrimp

scientific article published in December 2002

Hemolymph analysis and evaluation of newly formulated media for culture of shrimp cells (Penaeus stylirostris).

scientific article published on June 2001

Human furin is a calcium-dependent serine endoprotease that recognizes the sequence Arg-X-X-Arg and efficiently cleaves anthrax toxin protective antigen

scientific journal article

Identification of differentially expressed genes in shrimp (Penaeus stylirostris) infected with White spot syndrome virus by cDNA microarrays

scientific article published on 09 October 2003

Improvement in the specificity and sensitivity of detection for the Taura syndrome virus and yellow head virus of penaeid shrimp by increasing the amplicon size in SYBR Green real-time RT-PCR.

scientific article published in August 2003

In vitro processing of anthrax toxin protective antigen by recombinant PC1 (SPC3) and bovine intermediate lobe secretory vesicle membranes

scientific article published on January 1995

Infectious hypodermal and hematopoietic necrosis virus of shrimp is related to mosquito brevidensoviruses.

scientific article published on November 2000

Isolation and characterization of spontaneous avirulent variants of Histoplasma capsulatum

scientific article published on March 1987

Isolation of differentially expressed genes from white spot virus (WSV) infected Pacific blue shrimp (Penaeus stylirostris).

scientific article

Nucleotide sequence of 3'-end of the genome of Taura syndrome virus of shrimp suggests that it is related to insect picornaviruses

scientific article

Oligomerization of anthrax toxin protective antigen and binding of lethal factor during endocytic uptake into mammalian cells

scientific article

Proteolytic activation of bacterial toxins by eukaryotic cells is performed by furin and by additional cellular proteases

scientific article

Proteolytic inactivation of MAP-kinase-kinase by anthrax lethal factor

scientific article

Quantitative assay for measuring the Taura syndrome virus and yellow head virus load in shrimp by real-time RT-PCR using SYBR Green chemistry

scientific article published in June 2002

RAPD markers as predictors of infectious hypodermal and hematopoietic necrosis virus (IHHNV) resistance in shrimp (Litopenaeus stylirostris).

scientific article published in February 2002

Targeting HIV proteins to the major histocompatibility complex class I processing pathway with a novel gp120-anthrax toxin fusion protein

scientific article published on October 28, 1997

The Lipopolysaccharide and β-1,3-Glucan Binding Protein Gene Is Upregulated in White Spot Virus-Infected Shrimp (Penaeus stylirostris).

scientific article published in September 2002

The carboxyl-terminal end of protective antigen is required for receptor binding and anthrax toxin activity.

scientific article published in August 1991

The chymotrypsin-sensitive site, FFD315, in anthrax toxin protective antigen is required for translocation of lethal factor

scientific article published on 01 November 1994

The lipopolysaccharide and beta-1,3-glucan binding protein gene is upregulated in white spot virus-infected shrimp (Penaeus stylirostris)

scientific article