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List of works by Hua Zhang

A Cremophor-Free Self-Microemulsified Delivery System for Intravenous Injection of Teniposide: Evaluation In Vitro and In Vivo ⬇️

scientific article published on May 30, 2012

A Lipid Micellar System Loaded with Dexamethasone Palmitate Alleviates Rheumatoid Arthritis

scientific article published on 10 October 2019

A Nanosystem of Amphiphilic Oligopeptide-Drug Conjugate Actualizing Both αvβ3 Targeting and Reduction-Triggered Release for Maytansinoid.

scientific article

A combined "eat me/don't eat me" strategy based on extracellular vesicles for anticancer nanomedicine

scientific article published on 19 August 2020

A comparative investigation between paclitaxel nanoparticle- and nanocrystal-loaded thermosensitive PECT hydrogels for peri-tumoural administration

scientific article published in November 2016

A comparative study of the antitumor efficacy of peptide-doxorubicin conjugates with different linkers.

scientific article

A comparative study of thermo-sensitive hydrogels with water-insoluble paclitaxel in molecule, nanocrystal and microcrystal dispersions

scientific article

A comprehensive study of iRGD-modified liposomes with improved chemotherapeutic efficacy on B16 melanoma

scientific article published on 15 April 2014

A magnetism/laser-auxiliary cascaded drug delivery to pulmonary carcinoma

scientific article published on 03 January 2020

A multiaspect study on transcytosis mechanism of sorafenib nanogranules engineered by high-gravity antisolvent precipitation

scientific article published on 09 April 2020

A nanomedicine based combination therapy based on QLPVM peptide functionalized liposomal tamoxifen and doxorubicin against Luminal A breast cancer

scientific article published on 19 December 2015

A novel lanreotide-encoded micelle system targets paclitaxel to the tumors with overexpression of somatostatin receptors

scientific article

A novel localized co-delivery system with lapatinib microparticles and paclitaxel nanoparticles in a peritumorally injectable in situ hydrogel

scientific article published on 13 October 2015

A novel transdermal patch incorporating isosorbide dinitrate with bisoprolol: in vitro and in vivo characterization

scientific article published on 28 December 2006

A recombinant peptide, hirudin, potentiates the inhibitory effects of stealthy liposomal vinblastine on the growth and metastasis of melanoma

scientific article

A sensitive liquid chromatography/electrospray tandem mass spectroscopy method for simultaneous quantification of a disulfide bond doxorubicin conjugation prodrug and activated doxorubicin: Application to cellular pharmacokinetic and catabolism stud

scientific article published on 21 September 2017

A smart tumor targeting peptide-drug conjugate, pHLIP-SS-DOX: synthesis and cellular uptake on MCF-7 and MCF-7/Adr cells

scientific article

A specific peptide ligand-modified lipid nanoparticle carrier for the inhibition of tumor metastasis growth

scientific article

A tenascin C targeted nanoliposome with navitoclax for specifically eradicating of cancer-associated fibroblasts

scientific article published on 27 October 2015

Absorption mechanism of cyclosporine A loaded pH-sensitive nanoparticles in rats

scientific article published in May 2008

Anisotropic active ligandations in siRNA-Loaded hybrid nanodiscs lead to distinct carcinostatic outcomes by regulating nano-bio interactions

scientific article published on 03 April 2020

Bioavailability of tramadol hydrochloride after administration via different routes in rats

scientific article published on 27 September 2014

Bionano interactions of mcf-7 breast tumor cells with a transferrin receptor targeted nanoparticle

scientific article published on 06 April 2015

Circulating tumor DNA detection is correlated to histologic types in patients with early-stage non-small-cell lung cancer

scientific article published on 31 May 2019

Combination antitumor therapy with targeted dual-nanomedicines

scientific article published on 7 March 2017

Combined mTOR inhibitor rapamycin and doxorubicin-loaded cyclic octapeptide modified liposomes for targeting integrin α3 in triple-negative breast cancer.

scientific article

Comprehensively priming the tumor microenvironment by cancer-associated fibroblast-targeted liposomes for combined therapy with cancer cell-targeted chemotherapeutic drug delivery system.

scientific article

Controlled delivery of recombinant hirudin based on thermo-sensitive Pluronic F127 hydrogel for subcutaneous administration: In vitro and in vivo characterization

scientific article published on 05 December 2006

Cremophor-free intravenous self-microemulsions for teniposide: Safety, antitumor activity in vitro and in vivo.

scientific article published on 4 August 2015

Dual targeting for metastatic breast cancer and tumor neovasculature by EphA2-mediated nanocarriers

scientific article published on 21 May 2015

Dual-targeting nanovesicles enhance specificity to dynamic tumor cells <i>in vitro</i> and <i>in vivo via</i> manipulation of <i>α</i>v<i>β</i>3-ligand binding

scientific article published on 25 July 2020

Dynamic bio-adhesion of polymer nanoparticles on MDCK epithelial cells and its impact on bio-membranes, endocytosis and paracytosis

Effects of PEGylated paclitaxel nanocrystals on breast cancer and its lung metastasis

scientific article published on June 2015

Effects of pH-sensitive nanoparticles prepared with different polymers on the distribution, adhesion and transition of Rhodamine 6G in the gut of rats

scientific article published on 01 May 2010

Enhanced intracellular delivery and improved antitumor efficacy of doxorubicin by sterically stabilized liposomes modified with a synthetic RGD mimetic

scientific article published in October 2005

Enhanced intracellular uptake of sterically stabilized liposomal Doxorubicin in vitro resulting in improved antitumor activity in vivo

scientific article published on 8 June 2005

Enhanced therapeutic effects on the multi-drug resistant human leukemia cells in vitro and xenograft in mice using the stealthy liposomal vincristine plus quinacrine

scientific article published in August 2008

Free paclitaxel loaded PEGylated-paclitaxel nanoparticles: preparation and comparison with other paclitaxel systems in vitro and in vivo

scientific article published on 22 May 2014

Hydrophobic penetrating peptide PFVYLI-modified stealth liposomes for doxorubicin delivery in breast cancer therapy

scientific article published on 19 December 2013

Hypoglycemic effects of bis(maltolato)oxovanadium administered by different routes upon diabetic rats

scientific article

Increase of the pharmacological and pharmacokinetic efficacy of negatively charged polypeptide recombinant hirudin in rats via parenteral route by association with cationic liposomes

scientific article published on 7 March 2008

Increased cellular uptake of peptide-modified PEGylated gold nanoparticles

scientific article

Inhibition of metastatic tumor growth and metastasis via targeting metastatic breast cancer by chlorotoxin-modified liposomes

scientific article published on 28 February 2014

Intracellular delivery of doxorubicin with RGD-modified sterically stabilized liposomes for an improved antitumor efficacy: in vitro and in vivo

scientific article published on August 2005

Kras mutations increase telomerase activity and targeting telomerase is a promising therapeutic strategy for Kras-mutant NSCLC.

scientific article published on 18 June 2016

Lanreotide-conjugated PEG-DSPE micelles: an efficient nanocarrier targeting to somatostatin receptor positive tumors

scientific article

Localized co-delivery of collagenase and trastuzumab by thermosensitive hydrogels for enhanced antitumor efficacy in human breast xenograft

scientific article published on 01 November 2018

Long-term studies on the stability and oral bioavailability of cyclosporine A nanoparticle colloid

scientific article published on 16 May 2006

LyP-1 modification to enhance delivery of artemisinin or fluorescent probe loaded polymeric micelles to highly metastatic tumor and its lymphatics

scientific article

Macrophage mediated biomimetic delivery system for the treatment of lung metastasis of breast cancer

scientific article

Nano-encapsulated tryptanthrin derivative for combined anticancer therapy via inhibiting indoleamine 2,3-dioxygenase and inducing immunogenic cell death

scientific article published on 06 September 2019

Nanotoxicity comparison of four amphiphilic polymeric micelles with similar hydrophilic or hydrophobic structure

scientific article published on 03 October 2013

Nasal insulin delivery in the chitosan solution: in vitro and in vivo studies.

scientific article

Novel free-paclitaxel-loaded redox-responsive nanoparticles based on a disulfide-linked poly(ethylene glycol)-drug conjugate for intracellular drug delivery: synthesis, characterization, and antitumor activity in vitro and in vivo

scientific article

Pharmaceutical and pharmacokinetic characteristics of different types of fenofibrate nanocrystals prepared by different bottom-up approaches

scientific article published on 09 December 2013

Pharmacodynamics and pharmacokinetics of recombinant hirudin via four non-parenteral routes

Pharmacokinetics and treatment efficacy of camptothecin nanocrystals on lung metastasis.

scientific article

Pharmacokinetics, toxicity of nasal cilia and immunomodulating effects in Sprague-Dawley rats following intranasal delivery of thymopentin with or without absorption enhancers

scientific article published on 19 October 2005

Preparation and antitumor study of camptothecin nanocrystals ⬇️

scientific article published on June 14, 2011

Preparation and characterization of insulin nanoparticles employing chitosan and poly(methylmethacrylate/methylmethacrylic acid) copolymer

scientific article published on 01 September 2006

Preparation of doxorubicin-loaded stealth liposomes modified with RGD mimetic and cellular association in vitro

scientific article published in December 2005

Preparation of the albumin nanoparticle system loaded with both paclitaxel and sorafenib and its evaluationin vitroandin vivo ⬇️

scientific article published on June 27, 2011

Proteomic analysis of intracellular protein corona of nanoparticles elucidates nano-trafficking network and nano-bio interactions

scientific article published on 01 January 2020

Reduction Responsive Self-Assembled Nanoparticles Based on Disulfide-Linked Drug-Drug Conjugate with High Drug Loading and Antitumor Efficacy

scientific article published on 2 December 2015

Regulating Interactions Between Targeted Nanocarriers and Mononuclear Phagocyte System via an Esomeprazole-Based Preconditioning Strategy

scientific article published on 25 August 2020

Rho GTPases in A549 and Caco-2 cells dominating the endocytic pathways of nanocarbons with different morphologies

scientific article published on 27 July 2018

Serum Free or Not: Two Distinct Recycling Mechanisms Mediated by Alpha v Beta 3 Integrin.

scientific article

Small GTPases: Structure, biological function and its interaction with nanoparticles

scientific article published on 31 July 2018

Stabilized thiomer PAA-Cys-6MNA

scientific article

Sylysia 350/Eudragit S100 solid nanomatrix as a promising system for oral delivery of cyclosporine A

scientific article published on 15 November 2014

Targeting efficiency of RGD-modified nanocarriers with different ligand intervals in response to integrin αvβ3 clustering

scientific article published in May 2014

The Function and Mechanism of Preactivated Thiomers in Triggering Epithelial Tight Junctions Opening

article

The Improved Delivery to Breast Cancer Based on a Novel Nanocarrier Modified with High-Affinity Peptides Discovered by Phage Display

scientific article published on 28 June 2018

The Use ofa Hydrophobic Binding Peptide Modified Lipid Nanocarrier Improving Tumor Distribution and Antitumor Efficacy

scientific article published on June 2016

The development of site-specific drug delivery nanocarriers based on receptor mediation

scientific article published on 24 May 2014

The effect of hydrophilic and hydrophobic structure of amphiphilic polymeric micelles on their transport in epithelial MDCK cells

scientific article published on 25 May 2013

The effect of linkers on the self-assembling and anti-tumor efficacy of disulfide-linked doxorubicin drug-drug conjugate nanoparticles

scientific article published on 12 April 2018

The eradication of breast cancer and cancer stem cells using octreotide modified paclitaxel active targeting micelles and salinomycin passive targeting micelles ⬇️

scientific article published on October 22, 2011

The impact of a chlorotoxin-modified liposome system on receptor MMP-2 and the receptor-associated protein ClC-3.

scientific article published on 16 April 2014

The impact of receptor recycling on the exocytosis of αvβ3 integrin targeted gold nanoparticles.

scientific article

The modulation of tumor vessel permeability by thalidomide and its impacts on different types of targeted drug delivery systems in a sarcoma mouse model.

scientific article published on 12 July 2016

The reduction of tumor interstitial fluid pressure by liposomal imatinib and its effect on combination therapy with liposomal doxorubicin

scientific article published on 4 January 2013

The transport mechanisms of polymer nanoparticles in Caco-2 epithelial cells

scientific article published on 18 May 2013

The transport pathways of polymer nanoparticles in MDCK epithelial cells

scientific article published on 7 March 2013

The use of a tumor metastasis targeting peptide to deliver doxorubicin-containing liposomes to highly metastatic cancer

scientific article published on 31 August 2012

The use of electronic-neutral penetrating peptides cyclosporin A to deliver pro-apoptotic peptide: A possibly better choice than positively charged TAT.

scientific article published on 26 June 2017

The use of α-conotoxin ImI to actualize the targeted delivery of paclitaxel micelles to α7 nAChR-overexpressing breast cancer.

scientific article published on 13 December 2014

Thymopentin-loaded pH-sensitive chitosan nanoparticles for oral administration: preparation, characterization, and pharmacodynamics

scientific article

Transferrin receptor specific nanocarriers conjugated with functional 7peptide for oral drug delivery ⬇️

scientific article published on October 24, 2012

[Mechanism and clinical progress of molecular targeted cancer therapy].

scientific article

[The integrity study on PEG-PCL micelles transcellular transported across MDCK epithelial cell monolayer using FRET technology]

scientific article published in August 2016

[Transcellular process of coumarin 6 loaded PEG-PCL micelles on MDCK epithelial cells].

scientific article

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