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List of works by Chikako Harada

ASK1 in neurodegeneration

scientific article

Brimonidine suppresses loss of retinal neurons and visual function in a murine model of optic neuritis

scientific article

Caloric restriction promotes cell survival in a mouse model of normal tension glaucoma

scientific article published on 27 September 2016

DOCK8 is expressed in microglia, and it regulates microglial activity during neurodegeneration in murine disease models

scientific article published on 23 July 2019

Delayed Onset of Experimental Autoimmune Encephalomyelitis in Olig1 Deficient Mice ⬇️

scientific article published on September 29, 2010

Differential effects of N-acetylcysteine on retinal degeneration in two mouse models of normal tension glaucoma

Disappearance of p27(KIP1) and increase in proliferation of the lens cells after extraction of most of the fiber cells of the lens

scientific article published in June 2005

Distribution of p27(KIP1), cyclin D1, and proliferating cell nuclear antigen after retinal detachment

scientific article published on 17 March 2004

Diverse NF-kappaB expression in epiretinal membranes after human diabetic retinopathy and proliferative vitreoretinopathy

scientific article published on 15 January 2004

Dock GEFs and their therapeutic potential: neuroprotection and axon regeneration

scientific article published on 11 July 2014

Dock3 induces axonal outgrowth by stimulating membrane recruitment of the WAVE complex

scientific article

Dock3 overexpression and p38 MAPK inhibition synergistically stimulate neuroprotection and axon regeneration after optic nerve injury

scientific article published on 27 August 2014

Dock3 regulates BDNF-TrkB signaling for neurite outgrowth by forming a ternary complex with Elmo and RhoG.

scientific article published on 27 June 2012

Dock3 stimulates axonal outgrowth via GSK-3β-mediated microtubule assembly.

scientific article

Dock3-NMDA receptor interaction as a target for glaucoma therapy

scientific article published on 9 September 2016

Edaravone Prevents Retinal Degeneration in Adult Mice Following Optic Nerve Injury

scientific article

Edaravone suppresses retinal ganglion cell death in a mouse model of normal tension glaucoma.

scientific article

Effect of geranylgeranylacetone on optic neuritis in experimental autoimmune encephalomyelitis.

scientific article published on 16 July 2009

Effect of p75NTR on the regulation of naturally occurring cell death and retinal ganglion cell number in the mouse eye.

scientific article

Effect of p75NTR on the regulation of photoreceptor apoptosis in the rd mouse

scientific article published on 29 December 2005

Effect of photoreceptor degeneration on RNA splicing and expression of AMPA receptors.

scientific article published on 13 December 2006

Expression of NG2-positive cells during optic neuritis.

scientific article published in January 2010

Expression of intraocular peroxisome proliferator-activated receptor gamma in patients with proliferative diabetic retinopathy

scientific article published on 29 October 2014

Expression of maf-B mRNA in the epithelium around the eyelid closure of the mouse eye at embryonic day 18.

scientific article published on 19 November 2004

Expression of olig2 in retinal progenitor cells

scientific article published in March 2006

Expression of promyelocytic leukemia protein and vascular endothelial growth factor in aqueous humor and vitreous fluid in patients with proliferative diabetic retinopathy ⬇️

scientific article published on October 23, 2012

Function of glial cell network as a modulator of neural cell death during retinal degeneration

scientific article published in November 2004

Glia- and neuron-specific functions of TrkB signalling during retinal degeneration and regeneration ⬇️

scientific article published on February 8, 2011

Glycated albumin induces activation of activator protein-1 in retinal glial cells

scientific article published on 01 May 2007

Inactivation of NF1 in CNS causes increased glial progenitor proliferation and optic glioma formation

scientific article published on December 2005

Inhibition of glial cell activation ameliorates the severity of experimental autoimmune encephalomyelitis.

scientific article published on 30 August 2007

Interleukin-1 attenuates normal tension glaucoma-like retinal degeneration in EAAC1-deficient mice

scientific article published on 17 September 2009

Interleukin-1 stimulates glutamate uptake in glial cells by accelerating membrane trafficking of Na+/K+-ATPase via actin depolymerization

scientific article published on 10 March 2008

Involvement of p27(KIP1) degradation by Skp2 in the regulation of proliferation in response to wounding of corneal epithelium.

scientific article

Involvement of p27(KIP1) in proliferation of the retinal pigment epithelium and ciliary body

scientific article published on 9 March 2004

Involvement of p27KIP1 in the proliferation of the developing corneal endothelium

scientific article

Microglia-Müller glia cell interactions control neurotrophic factor production during light-induced retinal degeneration.

scientific article published on November 2002

Molecular regulation of visual system development: more than meets the eye.

scientific article published on February 2007

Neuroprotection, Growth Factors and BDNF-TrkB Signalling in Retinal Degeneration

scientific article

Neuroprotective effect of geranylgeranylacetone against ischemia-induced retinal injury.

scientific article published on 7 September 2007

Neurotrophic factor receptors in epiretinal membranes after human diabetic retinopathy

scientific article

Neurotrophin-3 is required for appropriate establishment of thalamocortical connections

scientific article published in November 2002

Normal tension glaucoma-like degeneration of the visual system in aged marmosets

scientific article published on 16 October 2019

Phosphorylation of extracellular signal-regulated kinase and p27(KIP1) after retinal detachment

scientific article published on 2 August 2005

Phosphorylation of p27(KIP1) in the developing retina and retinoblastoma

scientific article published in August 2005

Recent advances in genetically modified animal models of glaucoma and their roles in drug repositioning

scientific article published on 26 October 2018

Regulation of the severity of neuroinflammation and demyelination by TLR-ASK1-p38 pathway

scientific article

Role of apoptosis signal-regulating kinase 1 (ASK 1)-mediated signaling pathway during ischemic retinal injury

scientific article

Role of apoptosis signal-regulating kinase 1 in stress-induced neural cell apoptosis in vivo

scientific article published on January 2006

Role of cytokines and trophic factors in the pathogenesis of diabetic retinopathy

scientific article published on February 2005

Role of monocyte chemotactic protein-1 and nuclear factor kappa B in the pathogenesis of proliferative diabetic retinopathy

scientific article published on 30 May 2006

Role of neuritin in retinal ganglion cell death in adult mice following optic nerve injury.

scientific article published on 4 July 2018

Role of neurotrophin-4/5 in neural cell death during retinal development and ischemic retinal injury in vivo

scientific article published in February 2005

Role of ubiquitin carboxy terminal hydrolase-L1 in neural cell apoptosis induced by ischemic retinal injury in vivo

scientific journal article

Roles of the DOCK-D family proteins in a mouse model of neuroinflammation

scientific article published on 02 April 2020

Spermidine Alleviates Severity of Murine Experimental Autoimmune Encephalomyelitis ⬇️

scientific article published on 01 April 2011

Spermidine Ameliorates Neurodegeneration in a Mouse Model of Normal Tension Glaucoma

scientific article published in July 2015

Suppression of Oxidative Stress as Potential Therapeutic Approach for Normal Tension Glaucoma

scientific article published on 16 September 2020

Survival of Alpha and Intrinsically Photosensitive Retinal Ganglion Cells in NMDA-Induced Neurotoxicity and a Mouse Model of Normal Tension Glaucoma

scientific article published on 01 September 2019

Targeting Oxidative Stress for Treatment of Glaucoma and Optic Neuritis.

scientific article published on 8 February 2017

The Renin-Angiotensin System Regulates Neurodegeneration in a Mouse Model of Optic Neuritis

scientific article published on 14 September 2017

The potential role of glutamate transporters in the pathogenesis of normal tension glaucoma

scientific article

The role of cytokines and trophic factors in epiretinal membranes: involvement of signal transduction in glial cells

scientific article

Topical Ripasudil Suppresses Retinal Ganglion Cell Death in a Mouse Model of Normal Tension Glaucoma.

scientific article

Topical ripasudil stimulates neuroprotection and axon regeneration in adult mice following optic nerve injury

scientific article published on 24 September 2020

Transcription factor, SP1, in epiretinal membranes of patients with proliferative diabetic retinopathy

scientific article published on 4 January 2010

TrkB Signaling in Retinal Glia Stimulates Neuroprotection after Optic Nerve Injury

scientific article

Valproic acid and ASK1 deficiency ameliorate optic neuritis and neurodegeneration in an animal model of multiple sclerosis

scientific article published on 28 December 2016

Valproic acid prevents NMDA-induced retinal ganglion cell death via stimulation of neuronal TrkB receptor signaling

scientific journal article

Valproic acid prevents retinal degeneration in a murine model of normal tension glaucoma

scientific article published on 30 December 2014

[Proliferative regulation in the cornea and lens]

scientific article published on 01 November 2003

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