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List of works by Ronald T. Raines

1,3-Dipolar Cycloaddition with Diazo Groups: Noncovalent Interactions Overwhelm Strain

scientific article published on 06 September 2016

1,3-Dipolar Cycloadditions of Diazo Compounds in the Presence of Azides

scientific article (publication date: April 2016)

1,9-Bis(2-pyridyl)-1,2,8,9-tetrathia-5-oxanonane

scientific article

2005 Emil Thomas Kaiser Award

scientific article

4-chloroprolines: synthesis, conformational analysis, and effect on the collagen triple helix

scientific article

4-ketoproline: An electrophilic proline analog for bioconjugation

scientific article

5(6)-anti-Substituted-2-azabicyclo[2.1.1]hexanes: a nucleophilic displacement route

scientific article

A Boronic Acid Conjugate of Angiogenin that Shows ROS-Responsive Neuroprotective Activity

scientific article published on 25 January 2017

A Boronic Acid Conjugate of Angiogenin that Shows ROS-Responsive Neuroprotective Activity

A Divalent Protecting Group for Benzoxaboroles

scientific article

A Highly Active Immobilized Ribonuclease

article published in 2000

A Residue to Residue Hydrogen Bond Mediates the Nucleotide Specificity of Ribonuclease A

A conserved interaction with the chromophore of fluorescent proteins

scientific article published on 21 December 2011

A highly sensitive fluorogenic probe for cytochrome P450 activity in live cells

scientific article published on 10 June 2008

A key n→π* Interaction in N-acyl homoserine lactones

scientific article published on 26 February 2014

A misfolded but active dimer of bovine seminal ribonuclease.

scientific article

A novel fully human antitumor immunoRNase resistant to the RNase inhibitor

scientific article published on 11 December 2012

A phosphine-mediated conversion of azides into diazo compounds.

scientific article

A potent, versatile disulfide-reducing agent from aspartic acid

scientific article

A prevalent intraresidue hydrogen bond stabilizes proteins

scientific article

A ribonuclease zymogen activated by the NS3 protease of the hepatitis C virus

scientific article published in December 2006

A stereoelectronic effect in prebiotic nucleotide synthesis

scientific article

A synapomorphic disulfide bond is critical for the conformational stability and cytotoxicity of an amphibian ribonuclease

scientific article published on 01 July 2000

A tRNA splicing operon: Archease endows RtcB with dual GTP/ATP cofactor specificity and accelerates RNA ligation

scientific article

Activation of the prolyl hydroxylase oxygen-sensor results in induction of GLUT1, heme oxygenase-1, and nitric-oxide synthase proteins and confers protection from metabolic inhibition to cardiomyocytes

scientific article published on 20 March 2003

Adjacent cysteine residues as a redox switch

scientific article published in November 2001

Advances in Bioconjugation

scientific article

Affinity of monoclonal antibodies for Globo-series glycans

scientific article published on 14 July 2014

Amide-Amide and Amide-Water Hydrogen Bonds: Implications for Protein Folding and Stability

scientific article

An electronic effect on protein structure.

scientific article

An evaluation of peptide-bond isosteres

scientific article published on 12 July 2011

An evolved Mxe GyrA intein for enhanced production of fusion proteins

scientific article

An n→π* Interaction in the Bound Substrate of Aspartic Proteases Replicates the Oxyanion Hole

scientific article published on 29 November 2018

An n→π* interaction in aspirin: implications for structure and reactivity

scientific article published on 06 September 2011

An n→π* interaction reduces the electrophilicity of the acceptor carbonyl group

scientific article published on September 2013

Analysis of Receptor-Ligand Interactions

scientific article published on February 1995

Anchoring a cytoactive factor in a wound bed promotes healing

scientific article published on 27 March 2014

Angiogenin activates the astrocytic Nrf2/antioxidant-response element pathway and thereby protects murine neurons from oxidative stress

scientific article published on 20 August 2019

Antimicrobial Synergy of a Ribonuclease and a Peptide Secreted by Human Cells

scientific article published on 15 October 2020

Antitumor activity of ribonuclease multimers created by site-specific covalent tethering

scientific article

Arginine grafting to endow cell permeability

scientific article published on 23 February 2007

Arginine residues are more effective than lysine residues in eliciting the cellular uptake of onconase

scientific article

Assignments of RNase A by ADAPT-NMR and enhancer

scientific article

Binding energy and enzymatic catalysis

Binding of non-natural 3'-nucleotides to ribonuclease A.

scientific article published in February 2005

Bioavailable affinity label for collagen prolyl 4-hydroxylase

scientific article published on 30 April 2013

Boronate-mediated biologic delivery

scientific article published on 13 February 2012

Boronic Acid for the Traceless Delivery of Proteins into Cells

scientific article

Bovine brain ribonuclease is the functional homolog of human ribonuclease 1

scientific article

Bovine pancreatic ribonuclease: fifty years of the first enzymatic reaction mechanism

scientific article

Bovine seminal ribonuclease produced from a synthetic gene.

scientific article

Bright building blocks for chemical biology

scientific article

Bright ideas for chemical biology

scientific article

Carpe diubiquitin

scientific article published on November 2010

Catalysis by ribonuclease A is limited by the rate of substrate association

scientific article published in April 2003

Catalysis by the tumor-suppressor enzymes PTEN and PTEN-L.

scientific article published on 21 January 2015

Catalysis of Hydrogen-Deuterium Exchange Reactions by 4-Substituted Proline Derivatives

scientific article published on 14 January 2019

Catalysis of Protein Folding by Protein Disulfide Isomerase and Small-Molecule Mimics

scientific article (publication date: August 2003)

Catalysis of imido group hydrolysis in a maleimide conjugate

scientific article published on 7 September 2007

Catalysis of protein disulfide bond isomerization in a homogeneous substrate

scientific article published on September 2005

Catalysis of protein folding by an immobilized small-molecule dithiol

scientific article published in July 2003

Catalytic activity of bovine seminal ribonuclease is essential for its immunosuppressive and other biological activities

scientific article published on June 1995

Cellular uptake of ribonuclease A relies on anionic glycans

scientific article

Characterization of Protein Immobilization at Silver Surfaces by Near Edge X-ray Absorption Fine Structure Spectroscopy

Chemical Mechanism of DNA Cleavage by the Homing Endonuclease I-PpoI†

scientific article published on 01 December 1999

Chemical synthesis of proteins

scientific article

Chemoselectivity in chemical biology: acyl transfer reactions with sulfur and selenium

scientific article

Circular zymogens of human ribonuclease 1

scientific article published on 06 August 2019

Cleavage of 3',5'-pyrophosphate-linked dinucleotides by ribonuclease A and angiogenin

scientific article

Code for collagen's stability deciphered

scientific article published in Nature

Coevolution of RtcB and Archease created a multiple-turnover RNA ligase

scientific article

Collagen Prolyl 4-Hydroxylase as a Therapeutic Target.

scientific article published on 23 July 2018

Collagen stability: insights from NMR spectroscopic and hybrid density functional computational investigations of the effect of electronegative substituents on prolyl ring conformations

scientific article published in March 2002

Collagen structure and stability

scientific article

Compensating effects on the cytotoxicity of ribonuclease A variants

scientific article published in July 2003

Comprehensive comparison of the cytotoxic activities of onconase and bovine seminal ribonuclease

scientific article published on December 2003

Computer-aided breast cancer detection and diagnosis of masses using difference of Gaussians and derivative-based feature saliency

scientific article published in December 1997

Conformational Stability Is a Determinant of Ribonuclease A Cytotoxicity

scientific article published in Journal of Biological Chemistry

Conformational preferences of substrates for human prolyl 4-hydroxylase

scientific article

Conformational stability and catalytic activity of PTEN variants linked to cancers and autism spectrum disorders

scientific article

Conformational stability of collagen relies on a stereoelectronic effect

scientific article published in January 2001

Consequences of the Endogenous N-Glycosylation of Human Ribonuclease 1

scientific article published on 29 January 2019

Contrast Agents for Magnetic Resonance Imaging Synthesized with Ring-Opening Metathesis Polymerization

scientific article published in 2006

Contribution of a tyrosine side chain to ribonuclease A catalysis and stability

scientific article published on August 1996

Contribution of active-site residues to the function of onconase, a ribonuclease with antitumoral activity

scientific article published in October 2003

Contribution of electrostatics to the binding of pancreatic-type ribonucleases to membranes

scientific article published on 30 August 2013

Contribution of individual disulfide bonds to the oxidative folding of ribonuclease A.

scientific article

Contribution of tertiary amides to the conformational stability of collagen triple helices

scientific article

Convenient synthesis of collagen-related tripeptides for segment condensation

scientific article

Conversion of Fructose into 5-(Hydroxymethyl)furfural in Sulfolane

Conversion of azides into diazo compounds in water

scientific article published on 27 September 2013

Coulombic Forces in Protein−RNA Interactions: Binding and Cleavage by Ribonuclease A and Variants at Lys7, Arg10, and Lys66†

scientific article published in 1998

Coulombic effects of remote subsites on the active site of ribonuclease A

scientific article

Coulombic effects on the traceless Staudinger ligation in water

scientific article

Creating site-specific isopeptide linkages between proteins with the traceless Staudinger ligation.

scientific article

Creation of a zymogen

scientific article published on February 2003

Crystal structure of N-(3-oxo-butano-yl)-l-homoserine lactone.

scientific article published on 09 January 2016

Cyclic Peptide Mimetic of Damaged Collagen

scientific article published on 19 March 2020

Cytosolic Delivery of Proteins by Bioreversible Esterification

scientific article published on 4 October 2017

Cytosolic Uptake of Large Monofunctionalized Dextrans.

scientific article published on 12 April 2018

Cytotoxic ribonucleases: the dichotomy of Coulombic forces

scientific article published on 18 August 2007

Cytotoxicity of Bovine Seminal Ribonuclease: Monomer versus Dimer†

scientific article published in 2005

Cytotoxicity of paclitaxel in breast cancer is due to chromosome missegregation on multipolar spindles

scientific article

Daniel S. Kemp (1936-2020): A Pioneer of Bioorganic Chemistry

scientific article published on 01 October 2020

Decavanadate Inhibits Catalysis by Ribonuclease A

article published in 2000

Decreasing Distortion Energies without Strain: Diazo-Selective 1,3-Dipolar Cycloadditions

scientific article (publication date: 15 July 2016)

Degenerate DNA recognition by I-PpoI endonuclease.

scientific article

Delivery of Proteins and Nucleic Acids: Achievements and Challenges

scientific article published on 01 February 2019

Design and characterization of an HIV-specific ribonuclease zymogen

scientific article published on November 2008

Detection of boronic acids through excited-state intramolecular proton-transfer fluorescence

scientific article published on 7 October 2013

Diazo Compounds as Highly Tunable Reactants in 1,3-Dipolar Cycloaddition Reactions with Cycloalkynes().

scientific article published on January 2012

Diazo compounds for the bioreversible esterification of proteins

scientific article

Diazo groups endure metabolism and enable chemoselectivity in cellulo

scientific article

Dibromobimane as a Fluorescent Crosslinking Reagent

scientific article published on 01 February 1995

Differential Effects of Nitrogen Substitution in 5- and 6-Membered Aromatic Motifs

scientific article published on 12 June 2020

Dimer formation by a "monomeric" protein

scientific article published on October 2000

Direct and continuous assay for prolyl 4-hydroxylase

scientific article published on 7 December 2008

Disruption and formation of surface salt bridges are coupled to DNA binding by the integration host factor: a computational analysis

scientific article

Disruption of shape-complementarity markers to create cytotoxic variants of ribonuclease A.

scientific article published on 24 August 2005

Effect of 3-hydroxyproline residues on collagen stability

scientific article

Effect of bovine seminal ribonuclease and bovine pancreatic ribonuclease A on bovine oocyte maturation

scientific article published in October 2000

Effects of a second-generation human anti-ErbB2 ImmunoRNase on trastuzumab-resistant tumors and cardiac cells

scientific article published on 12 January 2014

Electronic and Steric Optimization of Fluorogenic Probes for Biomolecular Imaging

scientific article

Electronic and steric effects on the rate of the traceless Staudinger ligation

scientific article published on 03 March 2008

Endowing human pancreatic ribonuclease with toxicity for cancer cells

scientific article

Energetics of Catalysis by Ribonucleases: Fate of the 2',3'-Cyclic Phosphodiester Intermediate

scientific article published on 01 June 1994

Energetics of an n --> pi interaction that impacts protein structure.

scientific article

Engineering ribonuclease A: production, purification and characterization of wild-type enzyme and mutants at Gln11.

scientific article published on March 1995

Enzyme relaxation in the reaction catalyzed by triosephosphate isomerase: detection and kinetic characterization of two unliganded forms of the enzyme.

scientific article published in November 1987

Enzyme-Activated Fluorogenic Probes for Live-Cell and in Vivo Imaging

scientific article published on 06 July 2018

Esterification Delivers a Functional Enzyme into a Human Cell

scientific article published on 11 March 2019

Evans Osteotomy in the Adult Foot: An Anatomic Study of Structures at Risk

article

Evasion of ribonuclease inhibitor as a determinant of ribonuclease cytotoxicity

scientific article published on June 2008

Evolution of Ribonuclease Inhibitor by Exon Duplication

scientific article published in 2002

Evolutionary optimization of the catalytic effectiveness of an enzyme

scientific article

Excavating an active site: the nucleobase specificity of ribonuclease A

scientific article

Extending the Limits to Enzymatic Catalysis: Diffusion of Ribonuclease A in One Dimension†

scientific article published in 1999

Facile chemical functionalization of proteins through intein-linked yeast display

scientific article published on 22 August 2013

Fast, Facile, Hypersensitive Assays for Ribonucleolytic Activity

article

Fermentable sugars by chemical hydrolysis of biomass

scientific article

Fine-Tuning Strain and Electronic Activation of Strain-Promoted 1,3-Dipolar Cycloadditions with Endocyclic Sulfamates in SNO-OCTs

scientific article

Fluorescence assay for the binding of ribonuclease A to the ribonuclease inhibitor protein

scientific article

Fluorescence gel retardation assay to detect protein-protein interactions

scientific article published on January 2004

Fluorescence polarization assay to quantify protein-protein interactions

scientific article published on January 2004

Fluorogenic Assay for Inhibitors of HIV-1 Protease with Sub-picomolar Affinity

scientific article

Fluorogenic affinity label for the facile, rapid imaging of proteins in live cells

scientific article

Fluorogenic label for biomolecular imaging

scientific article

Fluorogenic label to quantify the cytosolic delivery of macromolecules

scientific article published on 22 January 2013

Fluorogenic probe for constitutive cellular endocytosis

scientific article published on April 2013

Functional Evolution of Ribonuclease Inhibitor: Insights from Birds and Reptiles

scientific article

Functional and structural analyses of N-acylsulfonamide-linked dinucleoside inhibitors of RNase A

scientific article

Gastric Inlet Patch Containing Submucosally Infiltrating Adenocarcinoma

article

General Acid/Base Catalysis in the Active Site ofEscherichia coliThioredoxin†

scientific article published on 01 December 1997

General Method for Site-Specific Protein Immobilization by Staudinger Ligation

Genetic screen to dissect protein-protein interactions: ribonuclease inhibitor-ribonuclease A as a model system

scientific article

Genetic selection for critical residues in ribonucleases.

scientific article

Genetic selection for dissociative inhibitors of designated protein-protein interactions

scientific article

Genetic selection for peptide inhibitors of angiogenin

scientific article

Genetic selection reveals the role of a buried, conserved polar residue

scientific article published on August 2007

Glycosylation of onconase increases its conformational stability and toxicity for cancer cells

scientific article published in March 2004

Green fluorescent protein chimeras to probe protein-protein interactions

scientific article

High-Level Soluble Production and Characterization of Porcine Ribonuclease Inhibitor

article

High-Yielding Staudinger Ligation of a Phosphinothioester and Azide To Form a Peptide

scientific article published on 01 January 2001

His···Asp Catalytic Dyad of Ribonuclease A: Conformational Stability of the Wild-Type, D121N, D121A, and H119A Enzymes†

scientific article published on 01 December 1998

Hox genes maintain critical roles in the adult skeleton

scientific article published on 13 March 2020

Human Collagen Prolyl 4-Hydroxylase Is Activated by Ligands for Its Iron Center

scientific article published on 16 May 2016

Human angiogenin is a potent cytotoxin in the absence of ribonuclease inhibitor

scientific article published on 10 May 2018

Human ribonuclease with a pendant poly(ethylene glycol) inhibits tumor growth in mice

scientific article published on August 2013

Hydrolytic stability of hydrazones and oximes

scientific article

Hyperconjugative Antiaromaticity Activates 4H-Pyrazoles as Inverse-Electron-Demand Diels-Alder Dienes

scientific article published on 07 October 2019

Hyperconjugative π → σ*CF Interactions Stabilize the Enol Form of Perfluorinated Cyclic Keto-Enol Systems

scientific article published on 02 May 2019

Identifying latent enzyme activities: substrate ambiguity within modern bacterial sugar kinases

scientific article

Imaging the binding ability of proteins immobilized on surfaces with different orientations by using liquid crystals

scientific article

Increasing the potency of a cytotoxin with an arginine graft

scientific article published on 22 October 2007

Increasing the secretory capacity of Saccharomyces cerevisiae for production of single-chain antibody fragments

scientific article published in August 1998

Inductive Effects on the Energetics of Prolyl Peptide Bond Isomerization:  Implications for Collagen Folding and Stability

scientific article

Inhibition of human pancreatic ribonuclease by the human ribonuclease inhibitor protein

scientific article

Insights on the conformational stability of collagen

scientific article

Interaction of nucleic acids with the glycocalyx

scientific article

Interaction of onconase with the human ribonuclease inhibitor protein

scientific article published on 16 October 2008

Interplay of hydrogen bonds and n→π* interactions in proteins

scientific article

Interstrand dipole-dipole interactions can stabilize the collagen triple helix

scientific article

Intimate interactions with carbonyl groups: dipole-dipole or n→π*?

scientific article published on 10 December 2012

Intraspecies regulation of ribonucleolytic activity

scientific article published on 23 October 2007

Intrinsic site-selectivity of ubiquitin dimer formation

scientific article published on 15 January 2015

Is glycine a surrogate for a D-amino acid in the collagen triple helix?

scientific article

Jeremy R. Knowles (1935-2008).

scientific article

KFERQ sequence in ribonuclease A-mediated cytotoxicity

scientific article published on 18 January 2002

Kinetics and thermodynamics of the interaction of 5-fluoro-2'-deoxyuridylate with thymidylate synthase

scientific article published in December 1987

Latent Fluorophore Based on the Trimethyl Lock

article published in 2005

Latent blue and red fluorophores based on the trimethyl lock

scientific article

Limits to Catalysis by Ribonuclease A.

scientific article published on December 1995

Macrocyclic Scaffold for the Collagen Triple Helix

scientific article published in 2006

Mechanism of Ribonuclease Cytotoxicity

scientific article published in Journal of Biological Chemistry

Mechanism of ribonuclease A endocytosis: analogies to cell-penetrating peptides

scientific article

Mechanistic studies on the pyridoxal phosphate enzyme 1-aminocyclopropane-1-carboxylate deaminase from Pseudomonas sp.

scientific article published on December 1981

Mechanistic studies on the reactions of bacterial methionine .gamma.-lyase with olefinic amino acids

scientific article published on 01 July 1981

Microscopic pKa values of Escherichia coli thioredoxin.

scientific article published in December 1997

Modulating collagen triple-helix stability with 4-chloro, 4-fluoro, and 4-methylprolines

scientific article published on January 2009

Modulation of an n→π* interaction with α-fluoro groups

scientific article published on 01 July 2010

Molecular basis for catabolism of the abundant metabolite trans-4-hydroxy-L-proline by a microbial glycyl radical enzyme

scientific article published on 17 March 2020

Multilayered films fabricated from an oligoarginine-conjugated protein promote efficient surface-mediated protein transduction

scientific article published on 2 February 2007

Native disulfide bond formation in proteins

scientific article

Nature of amide carbonyl--carbonyl interactions in proteins

scientific article published on June 2009

Nature's transitory covalent bond

scientific article published on 01 June 1997

Nucleoside Tetra- and Pentaphosphates Prepared Using a Tetraphosphorylation Reagent Are Potent Inhibitors of Ribonuclease A

scientific article published on 11 November 2019

O-acylation of hydroxyproline residues: effect on peptide-bond isomerization and collagen stability

scientific article

Olefin metathesis for chemical biology

scientific article published on 18 October 2008

Olefin metathesis in homogeneous aqueous media catalyzed by conventional ruthenium catalysts

scientific article published on 19 October 2007

Oligomers of a 5-carboxy-methanopyrrolidine β-amino acid. A search for order

scientific article published on 2 November 2010

Onconase cytotoxicity relies on the distribution of its positive charge

scientific article

Optimal interstrand bridges for collagen-like biomaterials.

scientific article

Optimized diazo scaffold for protein esterification

scientific article

Organocatalysts of oxidative protein folding inspired by protein disulfide isomerase

scientific article

Organocatalytic Conversion of Cellulose into a Platform Chemical

scientific article (publication date: 2013)

Origin of the stability conferred upon collagen by fluorination

scientific article published on 21 April 2009

Origin of the ‘inactivation’ of ribonuclease A at low salt concentration

scientific article published on 01 February 2000

PTENpred: A Designer Protein Impact Predictor for PTEN-related Disorders

scientific article published on 16 June 2016

Palladium-Protein Oxidative Addition Complexes by Amine-Selective Acylation

scientific article published on 15 December 2020

Pathway for polyarginine entry into mammalian cells

scientific article

Pauli Exclusion by n→π* Interactions: Implications for Paleobiology

scientific article published on 4 September 2024

Pentavalent Organo-Vanadates as Transition State Analogues for Phosphoryl Transfer Reactions

scientific article published on October 2000

Peptide Bond Isosteres:  Ester or (E)-Alkene in the Backbone of the Collagen Triple Helix

scientific article published in 2005

Peptide tags for a dual affinity fusion system.

scientific article

Peptides and peptidomimetics as prototypes

scientific article published on 6 November 2008

Peptides on the Rise

scientific article

Peptides that anneal to natural collagen in vitro and ex vivo

scientific article

Phenotype of ribonuclease 1 deficiency in mice

scientific article published on 03 May 2019

Polyarginine as a multifunctional fusion tag.

scientific article published in June 2005

Potent inhibition of ribonuclease A by oligo(vinylsulfonic acid).

scientific article published on 20 March 2003

Potentiation of ribonuclease cytotoxicity by a poly(amidoamine) dendrimer

scientific article published on 12 November 2010

Practical syntheses of 4-fluoroprolines

scientific article published on September 2008

Production of Rat Protein Disulfide Isomerase in Saccharomyces cerevisiae

article

Production of human pancreatic ribonuclease in Saccharomyces cerevisiae and Escherichia coli.

scientific article

Production of human prolyl 4-hydroxylase in Escherichia coli

scientific article published in December 2004

Prolyl 4-Hydroxylase: Substrate Isosteres in Which an (E)- or (Z)-Alkene Replaces the Prolyl Peptide Bond

scientific article published on 21 December 2016

Prolyl 4-hydroxylase

scientific article

Prolyl 4-hydroxylase is required for viability and morphogenesis in Caenorhabditis elegans

scientific article published on April 2000

Protein assembly by orthogonal chemical ligation methods

scientific article published in May 2003

Protein disulfide isomerase in spore germination and cell division

scientific article published on May 1997

Protein engineering with the traceless Staudinger ligation

scientific article published on January 2009

Protein prosthesis: 1,5-disubstituted[1,2,3]triazoles as cis-peptide bond surrogates

scientific article published on 3 October 2007

Protein prosthesis: a nonnatural residue accelerates folding and increases stability

scientific article

Protein prosthesis: a semisynthetic enzyme with a beta-peptide reverse turn

scientific article

Protein prosthesis: β-peptides as reverse-turn surrogates

scientific article published on 17 January 2013

Pyramidalization of a carbonyl C atom in (2S)-N-(seleno-acet-yl)proline methyl ester

scientific article published on 30 April 2013

Pyrazine-derived disulfide-reducing agent for chemical biology

scientific article

Quantitative analysis of the effect of salt concentration on enzymatic catalysis.

scientific article published in November 2001

Quantum mechanical origin of the conformational preferences of 4-thiaproline and its S-oxides

scientific article published on 12 March 2010

RNS2: a senescence-associated RNase of Arabidopsis that diverged from the S-RNases before speciation

scientific article

ROMP from ROMP: A New Approach to Graft Copolymer Synthesis

scientific article published on June 2009

Rapid cycloaddition of a diazo group with an unstrained dipolarophile

scientific article published on 28 April 2016

Rational design and evaluation of mammalian ribonuclease cytotoxins

scientific article

Reaction energetics of a mutant triosephosphate isomerase in which the active-site glutamate has been changed to aspartate

scientific article published in November 1986

Reaction mechanism and kinetics of the traceless Staudinger ligation

scientific article

Reactivity of intein thioesters: appending a functional group to a protein

scientific article

Reciprocity of steric and stereoelectronic effects in the collagen triple helix

scientific article published on June 2006

Reconstitution of a defunct glycolytic pathway via recruitment of ambiguous sugar kinases

scientific article published in August 2005

Replacing a Surface Loop Endows Ribonuclease A with Angiogenic Activity

scientific article published in Journal of Biological Chemistry

Replacing a single atom accelerates the folding of a protein and increases its thermostability

scientific article published on 23 June 2016

Review collagen-based biomaterials for wound healing

scientific article

Ribonuclease A

scientific article (publication date: 7 May 1998)

Ribonuclease S redux

scientific article published on 16 November 2010

Ribonuclease S-peptide as a carrier in fusion proteins.

scientific article

Ribonuclease a: revealing structure-function relationships with semisynthesis

scientific article published on August 1995

Ribonuclease inhibitor as an intracellular sentry

scientific article

Ribonuclease inhibitor regulates neovascularization by human angiogenin

scientific article published on May 2009

Ribonuclease inhibitor: structure and function

scientific article

Ribonuclease-Activated Cancer Prodrug

scientific article

Ribonucleases as novel chemotherapeutics : the ranpirnase example

scientific article

Ribonucleases endowed with specific toxicity for spermatogenic layers

scientific article

Ribonucleoside 3'-phosphates as pro-moieties for an orally administered drug

scientific article

Salicylaldimine Ruthenium Alkylidene Complexes: Metathesis Catalysts Tuned for Protic Solvents

scientific article

Secondary Forces in Protein Folding

scientific article published on 19 June 2019

Secretory ribonucleases are internalized by a dynamin-independent endocytic pathway

scientific article published on January 2003

Selective Inhibition of Collagen Prolyl 4-Hydroxylase in Human Cells

scientific article published on 4 November 2015

Selective inhibition of prolyl 4-hydroxylases by bipyridinedicarboxylates

scientific article

Selenocysteine in native chemical ligation and expressed protein ligation

scientific article published in May 2001

Self-Assembled Collagen-like Peptide Fibers as Templates for Metallic Nanowires

scientific article

Self-assembly of synthetic collagen triple helices

scholarly article

Semisynthesis and characterization of mammalian thioredoxin reductase

scientific article published on April 2006

Semisynthesis of Human Ribonuclease-S

scientific article published on 09 December 2020

Semisynthesis of Proteins Containing Selenocysteine

article

Semisynthesis of ribonuclease A using intein-mediated protein ligation.

scientific article

Sensitive fluorogenic substrate for alkaline phosphatase

scientific article

Separation of Lignin from Corn Stover Hydrolysate with Quantitative Recovery of Ionic Liquid

scientific article

Signature of n→π* interactions in α-helices

scientific article published on 26 April 2011

Signatures of n→π* interactions in proteins.

scientific article

Silencing an inhibitor unleashes a cytotoxic enzyme

scientific article published on June 2009

Simple chemical transformation of lignocellulosic biomass into furans for fuels and chemicals

scientific article published in February 2009

Simulated moving bed chromatography: separation and recovery of sugars and ionic liquid from biomass hydrolysates

scientific article

Site-Specific Protein Immobilization by Staudinger Ligation

scientific article published on 01 October 2003

Site-specific PEGylation endows a mammalian ribonuclease with antitumor activity

scientific article published on August 2011

Site-specific folate conjugation to a cytotoxic protein

scientific article published on 24 April 2011

Solvent Effects on the Energetics of Prolyl Peptide Bond Isomerization

scientific article

Stabilization of the collagen triple helix by O-methylation of hydroxyproline residues

scientific article

Staudinger Ligation of α-Azido Acids Retains Stereochemistry

scientific article published on 01 July 2002

Staudinger ligation of peptides at non-glycyl residues

scientific article

Staudinger ligation: a peptide from a thioester and azide.

scientific article published in June 2000

Stereoelectronic Effects Impact Glycan Recognition

scientific article published on 24 January 2020

Stereoelectronic and steric effects in side chains preorganize a protein main chain

scientific article

Stereoelectronic and steric effects in the collagen triple helix: toward a code for strand association

scientific article published in November 2005

Stereoelectronic effects on collagen stability: the dichotomy of 4-fluoroproline diastereomers

scientific article published in August 2003

Stereoelectronic effects on polyproline conformation

scientific article

Stilbene Boronic Acids Form a Covalent Bond with Human Transthyretin and Inhibit Its Aggregation

scientific article published on 18 September 2017

Stringency of the 2-His-1-Asp active-site motif in prolyl 4-hydroxylase

scientific article

Stronger and (now) longer synthetic collagen.

scientific article published on January 2009

Structural Basis for Catalysis by Onconase

scientific article

Structural Determinants of Enzymic Processivity

scientific article published on 01 May 1994

Structural changes to ribonuclease A and their effects on biological activity

scientific article published on 01 June 1999

Structure and function of Bacillus subtilis YphP, a prokaryotic disulfide isomerase with a CXC catalytic motif

scientific article

Structure and stability of the P93G variant of ribonuclease A.

scientific article

Structure of RNA 3′-phosphate cyclase bound to substrate RNA

scientific article (publication date: October 2014)

Structures of the Noncanonical RNA Ligase RtcB Reveal the Mechanism of Histidine Guanylylation

scientific article

Sub-picomolar Inhibition of HIV-1 Protease with a Boronic Acid

article

Substituted 2-azabicyclo[2.1.1]hexanes as constrained proline analogues: implications for collagen stability

scientific article published in December 2004

Substrate binding and turnover by the highly specific I-PpoI endonuclease.

scientific article

Sulfur Shuffle: Modulating Enzymatic Activity by Thiol-Disulfide Interchange

scientific article published on 01 May 2000

Symbiosis: Chemical biology at Wisconsin.

scientific article published in September 2006

Synthesis and characterization of a novel class of reducing agents that are highly neuroprotective for retinal ganglion cells

scientific article published on 24 August 2006

Synthesis and utility of fluorogenic acetoxymethyl ethers

scientific article published on January 2011

Synthesis of 5-fluoro- and 5-hydroxymethanoprolines via lithiation of N-BOC-methanopyrrolidines. Constrained Cγ-exo and Cγ-endo Flp and Hyp conformer mimics

scientific article published on 25 May 2012

Synthesis of conformationally constrained 5-fluoro- and 5-hydroxymethanopyrrolidines. Ring-puckered mimics of gauche- and anti-3-fluoro- and 3-hydroxypyrrolidines

scientific article published on 18 April 2011

Synthesis of furfural from xylose and xylan

scientific article

Synthetic surfaces for ribonuclease adsorption

scientific article published in January 2005

Target selection by natural and redesigned PUF proteins

scientific article

Templated Collagen "Double Helices" Maintain Their Structure

scientific article published on 08 January 2020

Terbium(III) Luminescence-Based Assay for Esterase Activity

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The CXC motif: a functional mimic of protein disulfide isomerase

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The CXXC motif: a rheostat in the active site.

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The CXXC motif: crystal structure of an active-site variant of Escherichia coli thioredoxin

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The CXXC motif: imperatives for the formation of native disulfide bonds in the cell.

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The Extent to Which Ribonucleases Cleave Ribonucleic Acid

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The Mechanistic Pathway of a Mutant Triosephosphate Isomerase

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The Ribonucleolytic Activity of Angiogenin†

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The aberrance of the 4S diastereomer of 4-hydroxyproline

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The essential function of protein-disulfide isomerase is to unscramble non-native disulfide bonds.

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The n→π* Interaction

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Thermodynamic Origin of Prolyl Peptide Bond Isomers

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Thioamides in the collagen triple helix

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Thiols and selenols as electron-relay catalysts for disulfide-bond reduction

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Translocation of a beta-peptide across cell membranes

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Trimethyl lock: a stable chromogenic substrate for esterases

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Trimethyl lock: a trigger for molecular release in chemistry, biology, and pharmacology

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Triosephosphate isomerase catalysis is diffusion controlled. Appendix: Analysis of triose phosphate equilibria in aqueous solution by 31P NMR.

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Triple, Mutually Orthogonal Bioorthogonal Pairs through the Design of Electronically Activated Sulfamate-Containing Cycloalkynes

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Tunable, post-translational hydroxylation of collagen Domains in Escherichia coli

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Tuning the pK(a) of fluorescein to optimize binding assays

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Using measurements of anchoring energies of liquid crystals on surfaces to quantify proteins captured by immobilized ligands

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Value of general Acid-base catalysis to ribonuclease a.

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Variants of ribonuclease inhibitor that resist oxidation

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Water-soluble phosphinothiols for traceless staudinger ligation and integration with expressed protein ligation

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X-ray structure of two crystalline forms of a streptomycete ribonuclease with cytotoxic activity

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Zinc(II)-mediated inhibition of a ribonuclease by an N-hydroxyurea nucleotide

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Zinc(II)-mediated inhibition of ribonuclease Sa by an N-hydroxyurea nucleotide and its basis

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[23] The S·tag fusion system for protein purification

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n --> pi* Interaction and n)(pi Pauli repulsion are antagonistic for protein stability

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n-->pi* interactions in proteins

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n→π* Interactions Are Competitive with Hydrogen Bonds

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n→π* interactions engender chirality in carbonyl groups

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n→π* interactions in poly(lactic acid) suggest a role in protein folding

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n→π* interactions of amides and thioamides: implications for protein stability

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n➝ π* Interactions Modulate the Properties of Cysteine Residues and Disulfide Bonds in Proteins

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tRNA ligase catalyzes the GTP-dependent ligation of RNA with 3'-phosphate and 5'-hydroxyl termini

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α/β-Peptide Foldamers Targeting Intracellular Protein-Protein Interactions with Activity in Living Cells

scientific article published on 28 August 2015