List of works - Stephen Michnick

A Nutrient-Responsive Pathway that Determines M Phase Timing through Control of B-Cyclin mRNA Stability ⬇️

scientific article published on May 23, 2013

A cDNA library functional screening strategy based on fluorescent protein complementation assays to identify novel components of signaling pathways

scientific article published in April 2004

A novel genetic screen implicates Elm1 in the inactivation of the yeast transcription factor SBF.

scientific article

A toolkit of protein-fragment complementation assays for studying and dissecting large-scale and dynamic protein-protein interactions in living cells.

scientific article published on March 2010

An in vivo map of the yeast protein interactome

scientific article

An infrared reporter to detect spatiotemporal dynamics of protein-protein interactions

scientific article (publication date: June 2014)

An interview with Stephen Michnick, Ph.D., associate professor, Department of Biochemistry, University of Montreal

scientific article

Atypical membrane topology and heteromeric function of Drosophila odorant receptors in vivo

scientific article

Beta-lactamase protein fragment complementation assays as in vivo and in vitro sensors of protein protein interactions

scientific article

Capturing protein interactions in the secretory pathway of living cells

scientific article

Chemical biology on PINs and NeeDLes

scientific article

Chemical genetic strategies to delineate MAP kinase signaling pathways using protein-fragment complementation assays (PCA).

scientific article published on November 2006

Chromatin- and transcription-related factors repress transcription from within coding regions throughout the Saccharomyces cerevisiae genome

scientific article (publication date: 11 November 2008)

Combining the Optimized Yeast Cytosine Deaminase Protein Fragment Complementation Assay and an In Vitro Cdk1 Targeting Assay to Study the Regulation of the γ-Tubulin Complex.

scientific article published on January 2016

Convergent preparation and photophysical characterization of dimaleimide dansyl fluorogens: elucidation of the maleimide fluorescence quenching mechanism

scientific article

De novo helical peptides as target sequences for a specific, fluorogenic protein labelling strategy

scientific article

Delineating functional principles of the bow tie structure of a kinase-phosphatase network in the budding yeast

scientific article

Detection of TAP family dimerizations by an in vivo assay in mammalian cells

scientific article

Displacement of N/Q-rich Peptides on TiO2Beads Enhances the Depth and Coverage of Yeast Phosphoproteome Analyses ⬇️

scientific article published on May 8, 2013

Dissection of Cdk1-cyclin complexes in vivo.

scientific article published on 09 September 2013

Dynamic visualization of expressed gene networks

scientific article

Evolution of domain-peptide interactions to coadapt specificity and affinity to functional diversity

scientific article

Exhaustive search of linear information encoding protein-peptide recognition

scientific article published on 20 April 2017

Exploration and optimization of substituted triazolothiadiazines and triazolopyridazines as PDE4 inhibitors

scientific article

Fast and accurate discovery of degenerate linear motifs in protein sequences

scientific article published on 10 September 2014

Hereditary inclusion body myopathy-linked p97/VCP mutations in the NH2 domain and the D1 ring modulate p97/VCP ATPase activity and D2 ring conformation

scientific article (publication date: August 2009)

IL23R (Interleukin 23 Receptor) Variants Protective against Inflammatory Bowel Diseases (IBD) Display Loss of Function due to Impaired Protein Stability and Intracellular Trafficking

scientific article published on 17 February 2016

Identification of ERGIC-53 as an intracellular transport receptor of alpha1-antitrypsin

scientific article

Identifying off-target effects and hidden phenotypes of drugs in human cells

scientific article published on 7 May 2006

In-vivo detection of binary PKA network interactions upon activation of endogenous GPCRs

scientific article published on 23 June 2015

Introduction to monitoring and manipulating signaling networks

scientific article published on 30 October 2006

Mapping biochemical networks with protein fragment complementation assays

scientific article published on January 2015

Mapping biochemical networks with protein-fragment complementation assays

scientific article published on January 2004

Mechanisms and Consequences of Macromolecular Phase Separation

scientific article published on May 2016

Molecular characterization of the evolution of phagosomes

scientific article

Overview of the Alliance for Cellular Signaling

scientific article

PKA regulatory subunits mediate synergy among conserved G-protein-coupled receptor cascades.

scientific article published on 20 December 2011

PKB/Akt modulates TGF-beta signalling through a direct interaction with Smad3.

scientific article published on 28 March 2004

Phosphorylation network rewiring by gene duplication

scientific article published on 05 July 2011

Protein Kinase C ζ Interacts with a Novel Binding Region of Gαq to Act as a Functional Effector

scientific article published on 17 February 2016

Protein abundance is key to distinguish promiscuous from functional phosphorylation based on evolutionary information

scientific article

Protein folding: defining a "standard" set of experimental conditions and a preliminary kinetic data set of two-state proteins

scientific article

Protein fragment complementation strategies for biochemical network mapping

scientific article published on December 2003

Proteomic characterization of phagosomal membrane microdomains during phagolysosome biogenesis and evolution

scientific article (publication date: November 2012)

Proteomics in living cells

scientific article published on March 2004

Regulation of apoptosis by the Ft1 protein, a new modulator of protein kinase B/Akt

scientific article

Sample preparation and analytical strategies for large-scale phosphoproteomics experiments

scientific article published on 06 June 2012

Specific targeting of the IL-23 receptor, using a novel small peptide noncompetitive antagonist, decreases the inflammatory response

scientific article published on 20 August 2014

Submitting antibodies to binding arbitration

scientific article

Synthesis of degenerated libraries of the ras-binding domain of raf and rapid selection of fast-folding and stable clones with the dihydrofolate reductase protein fragment complementation assay

scientific article published in January 2007

The antidepressant sertraline inhibits translation initiation by curtailing mammalian target of rapamycin signaling.

scientific article

The dichotomous pattern of IL-12r and IL-23R expression elucidates the role of IL-12 and IL-23 in inflammation

scientific article

The scaffold protein Ste5 directly controls a switch-like mating decision in yeast

scientific article

Universal strategies in research and drug discovery based on protein-fragment complementation assays

scientific article published on July 2007

Unravelling the Mechanism of TrkA-Induced Cell Death by Macropinocytosis in Medulloblastoma Daoy Cells

scientific article published on 8 August 2016

Using the beta-lactamase protein-fragment complementation assay to probe dynamic protein-protein interactions

scientific article

iVici: Interrelational Visualization and Correlation Interface

scientific article published on 30 December 2005

List of works by Stephen Michnick

A Nutrient-Responsive Pathway that Determines M Phase Timing through Control of B-Cyclin mRNA Stability ⬇️

A cDNA library functional screening strategy based on fluorescent protein complementation assays to identify novel components of signaling pathways

A novel genetic screen implicates Elm1 in the inactivation of the yeast transcription factor SBF.

A toolkit of protein-fragment complementation assays for studying and dissecting large-scale and dynamic protein-protein interactions in living cells.

An in vivo map of the yeast protein interactome

An infrared reporter to detect spatiotemporal dynamics of protein-protein interactions

An interview with Stephen Michnick, Ph.D., associate professor, Department of Biochemistry, University of Montreal

Atypical membrane topology and heteromeric function of Drosophila odorant receptors in vivo

Beta-lactamase protein fragment complementation assays as in vivo and in vitro sensors of protein protein interactions

Capturing protein interactions in the secretory pathway of living cells

Chemical biology on PINs and NeeDLes

Chemical genetic strategies to delineate MAP kinase signaling pathways using protein-fragment complementation assays (PCA).

Chromatin- and transcription-related factors repress transcription from within coding regions throughout the Saccharomyces cerevisiae genome

Combining the Optimized Yeast Cytosine Deaminase Protein Fragment Complementation Assay and an In Vitro Cdk1 Targeting Assay to Study the Regulation of the γ-Tubulin Complex.

Convergent preparation and photophysical characterization of dimaleimide dansyl fluorogens: elucidation of the maleimide fluorescence quenching mechanism

De novo helical peptides as target sequences for a specific, fluorogenic protein labelling strategy

Delineating functional principles of the bow tie structure of a kinase-phosphatase network in the budding yeast

Detection of TAP family dimerizations by an in vivo assay in mammalian cells

Displacement of N/Q-rich Peptides on TiO2Beads Enhances the Depth and Coverage of Yeast Phosphoproteome Analyses ⬇️

Dissection of Cdk1-cyclin complexes in vivo.

Dynamic visualization of expressed gene networks

Evolution of domain-peptide interactions to coadapt specificity and affinity to functional diversity

Exhaustive search of linear information encoding protein-peptide recognition

Exploration and optimization of substituted triazolothiadiazines and triazolopyridazines as PDE4 inhibitors

Fast and accurate discovery of degenerate linear motifs in protein sequences

Hereditary inclusion body myopathy-linked p97/VCP mutations in the NH2 domain and the D1 ring modulate p97/VCP ATPase activity and D2 ring conformation

IL23R (Interleukin 23 Receptor) Variants Protective against Inflammatory Bowel Diseases (IBD) Display Loss of Function due to Impaired Protein Stability and Intracellular Trafficking

Identification of ERGIC-53 as an intracellular transport receptor of alpha1-antitrypsin

Identifying off-target effects and hidden phenotypes of drugs in human cells

In-vivo detection of binary PKA network interactions upon activation of endogenous GPCRs

Introduction to monitoring and manipulating signaling networks

Mapping biochemical networks with protein fragment complementation assays

Mapping biochemical networks with protein-fragment complementation assays

Mechanisms and Consequences of Macromolecular Phase Separation

Molecular characterization of the evolution of phagosomes

Overview of the Alliance for Cellular Signaling

PKA regulatory subunits mediate synergy among conserved G-protein-coupled receptor cascades.

PKB/Akt modulates TGF-beta signalling through a direct interaction with Smad3.

Phosphorylation network rewiring by gene duplication

Protein Kinase C ζ Interacts with a Novel Binding Region of Gαq to Act as a Functional Effector

Protein abundance is key to distinguish promiscuous from functional phosphorylation based on evolutionary information

Protein folding: defining a "standard" set of experimental conditions and a preliminary kinetic data set of two-state proteins

Protein fragment complementation strategies for biochemical network mapping

Proteomic characterization of phagosomal membrane microdomains during phagolysosome biogenesis and evolution

Proteomics in living cells

Regulation of apoptosis by the Ft1 protein, a new modulator of protein kinase B/Akt

Sample preparation and analytical strategies for large-scale phosphoproteomics experiments

Specific targeting of the IL-23 receptor, using a novel small peptide noncompetitive antagonist, decreases the inflammatory response

Submitting antibodies to binding arbitration

Synthesis of degenerated libraries of the ras-binding domain of raf and rapid selection of fast-folding and stable clones with the dihydrofolate reductase protein fragment complementation assay

The antidepressant sertraline inhibits translation initiation by curtailing mammalian target of rapamycin signaling.

The dichotomous pattern of IL-12r and IL-23R expression elucidates the role of IL-12 and IL-23 in inflammation

The scaffold protein Ste5 directly controls a switch-like mating decision in yeast

Universal strategies in research and drug discovery based on protein-fragment complementation assays

Unravelling the Mechanism of TrkA-Induced Cell Death by Macropinocytosis in Medulloblastoma Daoy Cells

Using the beta-lactamase protein-fragment complementation assay to probe dynamic protein-protein interactions

iVici: Interrelational Visualization and Correlation Interface