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List of works by Maureen Dempster

1H-imidazo[4,5-c]pyridine-4-carbonitrile as cathepsin S inhibitors: separation of desired cellular activity from undesired tissue accumulation through optimization of basic nitrogen pka

scientific article published on 19 December 2010

2-Phenyl-9H-purine-6-carbonitrile derivatives as selective cathepsin S inhibitors

scientific article published on 15 June 2010

4-(3-Trifluoromethylphenyl)-pyrimidine-2-carbonitrile as cathepsin S inhibitors: N3, not N1 is critically important

scientific article

6-Phenyl-1H-imidazo[4,5-c]pyridine-4-carbonitrile as cathepsin S inhibitors

scientific article

Design and optimization of a series of novel 2-cyano-pyrimidines as cathepsin K inhibitors

scientific article

Dioxo-triazines as a novel series of cathepsin K inhibitors

scientific article

Discovery of potent, soluble and orally active TRPV1 antagonists. Structure-activity relationships of a series of isoxazoles

scientific article published on 26 January 2011

High-resolution crystal structures of factor XIa coagulation factor in complex with nonbasic high-affinity synthetic inhibitors

scientific article

Identification of potent, soluble, and orally active TRPV1 antagonists

scientific article published on 31 January 2011

Optimisation of 2-cyano-pyrimidine inhibitors of cathepsin K: improving selectivity over hERG

scientific article

Structure-activity studies of a novel series of isoxazole-3-carboxamide derivatives as TRPV1 antagonists

scientific article published on 23 December 2010

Therapeutic dosing of an orally active, selective cathepsin S inhibitor suppresses disease in models of autoimmunity

scientific article published on 24 March 2011

Trifluoromethylphenyl as P2 for ketoamide-based cathepsin S inhibitors

scientific article

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