List of works - Baltazar Becerril

(1)H, (13)C and (15)N resonance assignment of 6aJL2(R25G), a highly fibrillogenic lambdaVI light chain variable domain

scientific article published on 22 August 2007

A novel class of peptide found in scorpion venom with neurodepressant effects in peripheral and central nervous system of the rat.

scientific article

A novel conotoxin from Conus delessertii with posttranslationally modified lysine residues

scientific article published in August 2005

A novel human recombinant antibody fragment capable of neutralizing Mexican scorpion toxins.

scientific article

A single mutation at the sheet switch region results in conformational changes favoring lambda6 light-chain fibrillogenesis

scientific article

A single mutation in framework 2 of the heavy variable domain improves the properties of a diabody and a related single-chain antibody

article

A strategy for the generation of specific human antibodies by directed evolution and phage display. An example of a single-chain antibody fragment that neutralizes a major component of scorpion venom

scientific article

Analysis of the immune response induced by a scorpion venom sub-fraction, a pure peptide and a recombinant peptide, against toxin Cn2 of Centruroides noxius Hoffmann

scientific article published in March 2003

Antibody BCF2 against scorpion toxin cn2 fromCentruroides noxius hoffmann: Primary structure and three-dimensional model as free fv fragment and complexed with its antigen

scholarly article by Barbara Selisko published in October 1999

Bacterial expression, purification and functional characterization of a recombinant chimeric Fab derived from murine mAb BCF2 that neutralizes the venom of the scorpion Centruroides noxius hoffmann

scientific article published in January 2004

Biochemical, electrophysiological and immunological characterization of the venom from Centruroides baergi, a new scorpion species of medical importance in Mexico

scientific article published on 29 May 2020

Broadening the neutralizing capacity of a family of antibody fragments against different toxins from Mexican scorpions

scientific article

Characterization of monoclonal anti-beta2-glycoprotein-I and anti-prothrombin antibody fragments generated by phage display from a patient with primary antiphospholipid syndrome.

scientific article published on 5 December 2005

Comparative assessment of the VH-VL and VL-VH orientations of single-chain variable fragments of scorpion toxin-neutralizing antibodies

scientific article published on 29 April 2020

Design and validation of a synthetic VH repertoire with tailored diversity for protein recognition

scientific article

Evaluation of three different formats of a neutralizing single chain human antibody against toxin Cn2: neutralization capacity versus thermodynamic stability

scientific article published on 28 January 2012

Exploiting cross-reactivity to neutralize two different scorpion venoms with one single chain antibody fragment

scientific article

Functional and immuno-reactive characterization of a previously undescribed peptide from the venom of the scorpion Centruroides limpidus

scientific article published on 18 November 2016

Gene cloning and functional characterization of four novel antimicrobial-like peptides from scorpions of the family Vaejovidae

scientific article

Generation of a Broadly Cross-Neutralizing Antibody Fragment against Several Mexican Scorpion Venoms

article

Generation of a recombinant antivenom against scorpion stings in Mexico

scientific article published on 01 April 2020

Identification of Bacillus thuringiensis Cry3Aa toxin domain II loop 1 as the binding site of Tenebrio molitor cadherin repeat CR12.

scientific article published on 17 February 2015

Influence of the germline sequence on the thermodynamic stability and fibrillogenicity of human lambda 6 light chains

scientific article published on 01 August 2008

Intraspecific variation of Centruroides sculpturatus scorpion venom from two regions of Arizona

scientific article published on 16 December 2017

Isolation and characterization of a human antibody fragment specific for Ts1 toxin from Tityus serrulatus scorpion ⬇️

scientific article published on May 19, 2011

Isolation, chemical and functional characterization of several new K(+)-channel blocking peptides from the venom of the scorpion Centruroides tecomanus

scientific article published on 24 February 2016

Novel alpha-KTx peptides from the venom of the scorpion Centruroides elegans selectively blockade Kv1.3 over IKCa1 K+ channels of T cells

scientific article published on September 2005

Novel alpha-conotoxins from Conus spurius and the alpha-conotoxin EI share high-affinity potentiation and low-affinity inhibition of nicotinic acetylcholine receptors.

scientific article

Novel interactions between K+ channels and scorpion toxins

scientific article

Optimal Neutralization of Centruroides noxius Venom Is Understood through a Structural Complex between Two Antibody Fragments and the Cn2 Toxin.

scientific article

Peptides from the scorpion Vaejovis punctatus with broad antimicrobial activity.

scientific article published on 4 September 2015

Phage versus phagemid libraries for generation of human monoclonal antibodies.

scientific article

Precursor De13.1 from Conus delessertii defines the novel G gene superfamily.

scientific article published on 20 January 2013

Proteomic analysis of the venom from the fish eating coral snake Micrurus surinamensis: novel toxins, their function and phylogeny.

scientific article

Proteomics of the venom from the Amazonian scorpion Tityus cambridgei and the role of prolines on mass spectrometry analysis of toxins.

scientific article

Simple approach for ranking structure determining residues

scientific article published on 22 June 2016

Site-directed mutagenesis reveals regions implicated in the stability and fiber formation of human λ3r light chains

scientific article

Site-directed mutagenesis reveals regions implicated in the stability and fiber formation of human λ3r light chains.

scientific article

Specific epitopes of domains II and III of Bacillus thuringiensis Cry1Ab toxin involved in the sequential interaction with cadherin and aminopeptidase-N receptors in Manduca sexta

scientific article published on 12 September 2006

Stabilizing an amyloidogenic λ6 light chain variable domain

scientific article published on 12 September 2017

Structural Basis of Neutralization of the Major Toxic Component from the Scorpion Centruroides noxius Hoffmann by a Human-derived Single-chain Antibody Fragment

scientific article

The Dual α-Amidation System in Scorpion Venom Glands

scientific article published on 20 July 2019

The change of the scFv into the Fab format improves the stability and in vivo toxin neutralization capacity of recombinant antibodies

article by Veronica Quintero-Hernández et al published February 2007 in Molecular Immunology

The three-dimensional structure of the toxic peptide Cl13 from the scorpion Centruroides limpidus

scientific article published on 19 June 2020

Thermodynamic and kinetic characterization of a germ line human lambda6 light-chain protein: the relation between unfolding and fibrillogenesis.

scientific article published on 6 January 2009

Transcriptome analysis of scorpion species belonging to the Vaejovis genus

scientific article

Two novel ergtoxins, blockers of K+-channels, purified from the Mexican scorpion Centruroides elegans elegans

scientific article

Updating knowledge on new medically important scorpion species in Mexico

scientific article

List of works by Baltazar Becerril

(1)H, (13)C and (15)N resonance assignment of 6aJL2(R25G), a highly fibrillogenic lambdaVI light chain variable domain

A novel class of peptide found in scorpion venom with neurodepressant effects in peripheral and central nervous system of the rat.

A novel conotoxin from Conus delessertii with posttranslationally modified lysine residues

A novel human recombinant antibody fragment capable of neutralizing Mexican scorpion toxins.

A single mutation at the sheet switch region results in conformational changes favoring lambda6 light-chain fibrillogenesis

A single mutation in framework 2 of the heavy variable domain improves the properties of a diabody and a related single-chain antibody

A strategy for the generation of specific human antibodies by directed evolution and phage display. An example of a single-chain antibody fragment that neutralizes a major component of scorpion venom

Analysis of the immune response induced by a scorpion venom sub-fraction, a pure peptide and a recombinant peptide, against toxin Cn2 of Centruroides noxius Hoffmann

Antibody BCF2 against scorpion toxin cn2 fromCentruroides noxius hoffmann: Primary structure and three-dimensional model as free fv fragment and complexed with its antigen

Bacterial expression, purification and functional characterization of a recombinant chimeric Fab derived from murine mAb BCF2 that neutralizes the venom of the scorpion Centruroides noxius hoffmann

Biochemical, electrophysiological and immunological characterization of the venom from Centruroides baergi, a new scorpion species of medical importance in Mexico

Broadening the neutralizing capacity of a family of antibody fragments against different toxins from Mexican scorpions

Characterization of monoclonal anti-beta2-glycoprotein-I and anti-prothrombin antibody fragments generated by phage display from a patient with primary antiphospholipid syndrome.

Comparative assessment of the VH-VL and VL-VH orientations of single-chain variable fragments of scorpion toxin-neutralizing antibodies

Design and validation of a synthetic VH repertoire with tailored diversity for protein recognition

Evaluation of three different formats of a neutralizing single chain human antibody against toxin Cn2: neutralization capacity versus thermodynamic stability

Exploiting cross-reactivity to neutralize two different scorpion venoms with one single chain antibody fragment

Functional and immuno-reactive characterization of a previously undescribed peptide from the venom of the scorpion Centruroides limpidus

Gene cloning and functional characterization of four novel antimicrobial-like peptides from scorpions of the family Vaejovidae

Generation of a Broadly Cross-Neutralizing Antibody Fragment against Several Mexican Scorpion Venoms

Generation of a recombinant antivenom against scorpion stings in Mexico

Identification of Bacillus thuringiensis Cry3Aa toxin domain II loop 1 as the binding site of Tenebrio molitor cadherin repeat CR12.

Influence of the germline sequence on the thermodynamic stability and fibrillogenicity of human lambda 6 light chains

Intraspecific variation of Centruroides sculpturatus scorpion venom from two regions of Arizona

Isolation and characterization of a human antibody fragment specific for Ts1 toxin from Tityus serrulatus scorpion ⬇️

Isolation, chemical and functional characterization of several new K(+)-channel blocking peptides from the venom of the scorpion Centruroides tecomanus

Novel alpha-KTx peptides from the venom of the scorpion Centruroides elegans selectively blockade Kv1.3 over IKCa1 K+ channels of T cells

Novel alpha-conotoxins from Conus spurius and the alpha-conotoxin EI share high-affinity potentiation and low-affinity inhibition of nicotinic acetylcholine receptors.

Novel interactions between K+ channels and scorpion toxins

Optimal Neutralization of Centruroides noxius Venom Is Understood through a Structural Complex between Two Antibody Fragments and the Cn2 Toxin.

Peptides from the scorpion Vaejovis punctatus with broad antimicrobial activity.

Phage versus phagemid libraries for generation of human monoclonal antibodies.

Precursor De13.1 from Conus delessertii defines the novel G gene superfamily.

Proteomic analysis of the venom from the fish eating coral snake Micrurus surinamensis: novel toxins, their function and phylogeny.

Proteomics of the venom from the Amazonian scorpion Tityus cambridgei and the role of prolines on mass spectrometry analysis of toxins.

Simple approach for ranking structure determining residues

Site-directed mutagenesis reveals regions implicated in the stability and fiber formation of human λ3r light chains

Site-directed mutagenesis reveals regions implicated in the stability and fiber formation of human λ3r light chains.

Specific epitopes of domains II and III of Bacillus thuringiensis Cry1Ab toxin involved in the sequential interaction with cadherin and aminopeptidase-N receptors in Manduca sexta

Stabilizing an amyloidogenic λ6 light chain variable domain

Structural Basis of Neutralization of the Major Toxic Component from the Scorpion Centruroides noxius Hoffmann by a Human-derived Single-chain Antibody Fragment

The Dual α-Amidation System in Scorpion Venom Glands

The change of the scFv into the Fab format improves the stability and in vivo toxin neutralization capacity of recombinant antibodies

The three-dimensional structure of the toxic peptide Cl13 from the scorpion Centruroides limpidus

Thermodynamic and kinetic characterization of a germ line human lambda6 light-chain protein: the relation between unfolding and fibrillogenesis.

Transcriptome analysis of scorpion species belonging to the Vaejovis genus

Two novel ergtoxins, blockers of K+-channels, purified from the Mexican scorpion Centruroides elegans elegans

Updating knowledge on new medically important scorpion species in Mexico