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List of works by Raymond W. Tennant

12-O-Tetradecanoylphorbol-13-acetate and UV Radiation-induced Nucleoside Diphosphate Protein Kinase B Mediates Neoplastic Transformation of Epidermal Cells ⬇️

scientific article published on November 17, 2003

A farnesyl transferase inhibitor suppresses TPA-mediated skin tumor development without altering hyperplasia in the ras transgenic Tg.AC mouse

scientific article published on 01 January 2000

A novel role for the T-box transcription factor Tbx1 as a negative regulator of tumor cell growth in mice.

scientific article

A transgenic mouse model (TG.AC) for skin carcinogenesis: inducible transgene expression as a second critical event

scientific article published on January 1995

Age-dependent skin tumorigenesis and transgene expression in the Tg.AC (v-Ha-ras) transgenic mouse

scientific article

Arsenic exposure in utero exacerbates skin cancer response in adulthood with contemporaneous distortion of tumor stem cell dynamics

scientific article

Association of tumor development with increased cellular proliferation and transgene overexpression, but not c-Ha-ras mutations, in v-Ha-ras transgenic Tg.AC mice

scientific article published on 01 September 1996

Biological, cellular, and molecular characteristics of an inducible transgenic skin tumor model: a review

scientific article

Blood gene expression signatures predict exposure levels.

scholarly article

CD34 Antigen: Determination of Specific Sites of Phosphorylation In Vitro and In Vivo.

scientific article

CD34 expression by hair follicle stem cells is required for skin tumor development in mice

scientific article

CEBS--Chemical Effects in Biological Systems: a public data repository integrating study design and toxicity data with microarray and proteomics data.

scientific article

Cadmium-induced toxicity in rat primary mid-brain neuroglia cultures: role of oxidative stress from microglia.

scientific article published on 5 May 2007

Chemically induced skin carcinogenesis in a transgenic mouse line (TG.AC) carrying a v-Ha-ras gene

scientific article published on July 1993

Chemoprevention of UV light-induced skin tumorigenesis by inhibition of the epidermal growth factor receptor.

scientific article

Comparative evaluation of genetic toxicity patterns of carcinogens and noncarcinogens: strategies for predictive use of short-term assays.

scientific article

Comparative evaluation of three mammalian cell transformation assay systems.

scientific article

Comparison of multiple parameters of rodent carcinogenicity and in vitro genetic toxicity.

scientific article published in January 1986

Comprehensive microarray transcriptome profiling of CD34-enriched mouse keratinocyte stem cells

scientific article published on 21 June 2007

Cytogenetic analysis of malignant skin tumors induced in chemically treated TG-AC transgenic mice

scientific article published on 01 December 1994

Decreases in phorbol ester–induced papilloma development in v-Ha-ras transgenic TG.AC mice during reduced gene dosage ofbcl-2 ⬇️

scientific article published on September 1, 1997

Development of a transgenic mouse model for carcinogenesis bioassays: evaluation of chemically induced skin tumors in Tg.AC mice

scientific article published on 01 June 1999

Enrichment for living murine keratinocytes from the hair follicle bulge with the cell surface marker CD34.

scientific article published on April 2003

Erbb2 suppresses DNA damage-induced checkpoint activation and UV-induced mouse skin tumorigenesis

scientific article published on 30 April 2009

Evaluation of four in vitro genetic toxicity tests for predicting rodent carcinogenicity: confirmation of earlier results with 41 additional chemicals

scientific article published on January 1990

Evidence that toxic injury is not always associated with induction of chemical carcinogenesis ⬇️

scientific article published on January 1, 1991

Gene expression analysis reveals chemical-specific profiles

scientific article published on 01 June 2002

Gene expression profiling of rat livers reveals indicators of potential adverse effects.

scientific article published on 14 April 2004

Gene expression response in target organ and whole blood varies as a function of target organ injury phenotype

scientific article published on 20 June 2008

Genetic toxicology: current status of methods of carcinogen identification

scientific article

Genetically altered mouse models for identifying carcinogens

scientific article

Global gene expression associated with hepatocarcinogenesis in adult male mice induced by in utero arsenic exposure

scientific article

Hemizygous Tg.AC transgenic mouse as a potential alternative to the two-year mouse carcinogenicity bioassay: evaluation of husbandry and housing factors ⬇️

scientific article published on 01 January 1998

Identification of Dss1 as a 12-O-tetradecanoylphorbol-13-acetate-responsive gene expressed in keratinocyte progenitor cells, with possible involvement in early skin tumorigenesis

scientific article published on 4 November 2002

Identification of a specific motif of the DSS1 protein required for proteasome interaction and p53 protein degradation.

scientific article published on 26 August 2008

Identification of genes and gene ontology processes critical to skin papilloma development in Tg.AC transgenic mice

scientific article published on February 2006

Identification of putative gene based markers of renal toxicity

scientific article

Identifying chemical carcinogens and assessing potential risk in short-term bioassays using transgenic mouse models

scientific article

Induction of transgene expression in Tg.AC (v-Ha-ras) transgenic mice concomitant with DNA hypomethylation ⬇️

scientific article published on April 1, 1998

Kinetics of wound-induced v-Ha-ras transgene expression and papilloma development in transgenic Tg.AC mice ⬇️

scientific article published on September 1, 1997

Loss of heterozygosity frequency at the Trp53 locus in p53-deficient (+/-) mouse tumors is carcinogen-and tissue-dependent

scientific article

Mechanism of skin tumorigenesis by contact sensitizers: the effect of the corticosteroid fluocinolone acetonide on inflammation and tumor induction by 2,4 dinitro-1-fluorobenzene in the skin of the TG.AC (v-Ha-ras) mouse

scientific article

Methapyrilene toxicity: anchorage of pathologic observations to gene expression alterations.

scientific article published in July 2002

Morphological Characterization of Spindle Cell Tumors Induced in Transgenic Tg.AC Mouse Skin ⬇️

scientific article published on July 1, 1998

Mouse population-guided resequencing reveals that variants in CD44 contribute to acetaminophen-induced liver injury in humans

scientific article published on 05 May 2009

New animals, new uses, and old issues

scientific article published on 01 January 1996

Oral administration of dimethylvinyl chloride increases frequency of forestomach papillomas in Tg.AC mice

scientific article

Photocarcinogenesis and Susceptibility to UV Radiation in the v-Ha-ras Transgenic Tg.AC Mouse ⬇️

scientific article published on 01 September 1998

Photocarcinogenesis in the Tg.AC mouse: lomefloxacin and 8-methoxypsoralen

scientific article published on January 2003

Predicting chemical carcinogenesis in rodents

scientific article

Prediction of chemical carcinogenicity in rodents from in vitro genetic toxicity assays.

scientific article published in May 1987

Prediction of compound signature using high density gene expression profiling

scientific article published on June 2002

Predictions for the outcome of rodent carcinogenicity bioassays: identification of trans-species carcinogens and noncarcinogens

scientific article

Reduced skin tumor development in cyclin D1-deficient mice highlights the oncogenic ras pathway in vivo ⬇️

scientific article published on August 15, 1998

Response: do short-term tests predict rodent carcinogenicity?

scientific article published on 01 September 1988

Responses of transgenic mouse lines p53(+/-) and Tg.AC to agents tested in conventional carcinogenicity bioassays

scientific article

Standardizing global gene expression analysis between laboratories and across platforms.

scientific article

Statistical analysis of skin tumor data from Tg.AC mouse bioassays

scientific article

Systems Toxicology and the Chemical Effects in Biological Systems (CEBS) Knowledge Base

scientific article published in 2002

Systems toxicology and the Chemical Effects in Biological Systems (CEBS) knowledge base

scientific article published on January 1, 2003

TGFα is Dispensable for Skin Tumorigenesis in Tg.AC Mice ⬇️

scientific article published on 01 July 1998

Tg.AC genetically altered mouse: assay working group overview of available data

scientific article

The Tg.AC (v-Ha-ras) transgenic mouse: nature of the model

scientific article (publication date: 2001)

The transgenic Tg.AC mouse model for identification of chemical carcinogens.

scientific article published in December 1998

The use of transgenic animals in cancer testing

scientific article

Toward a checklist for exchange and interpretation of data from a toxicology study

scientific article

Transformation of BALB/c-3T3 cells: IV. Rank-ordered potency of 24 chemical responses detected in a sensitive new assay procedure

scientific article

Transformation of BALB/c-3T3 cells: V. Transformation responses of 168 chemicals compared with mutagenicity in Salmonella and carcinogenicity in rodent bioassays

scientific article

Transplacental exposure to inorganic arsenic at a hepatocarcinogenic dose induces fetal gene expression changes in mice indicative of aberrant estrogen signaling and disrupted steroid metabolism

scientific article published on 06 February 2007

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