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List of works by Theodore E Gram

A comparison of the effects of halothane and CCl 4 on the hepatic drug metabolizing system

scientific article published in June 1971

A comparison of the pulmonary toxicity and chemotherapeutic activity of bleomycin-BAPP to bleomycin and pepleomycin ⬇️

scientific article published on January 1, 1984

A comprehensive study of in vitro drug metabolism in several laboratory species ⬇️

scientific article published on May 1, 1976

A possible role for membrane lipid peroxidation in anthracycline nephrotoxicity

scientific article published in December 1986

Activation of pharmacologic agents to radical intermediates. Implications for the role of free radicals in drug action and toxicity

scientific article published on November 1982

Acute toxicity of substrates of the mixed function oxidase system in normal and phenobarbital-pretreated mice

scientific article published on September 1, 1975

Alterations in kinetic constants for hepatic microsomal aniline hydroxylase and ethylmorphine N-demethylase associated with pregnancy in rats ⬇️

scientific article published on 01 August 1969

Analysis of platinum in biological materials by flameless atomic absorption spectrophotometry

scientific article published on 01 October 1977

Bleomycin-metal interaction: Ferrous iron-initiated chemiluminescence ⬇️

scientific article published on April 29, 1983

Bronchiolar epithelial damage and impairment of pulmonary microsomal monooxygenase activity in mice by naphthalene

scientific article published on 01 December 1982

Changes in Michaelis and spectral constants for aniline in hepatic microsomes from phenobarbital-treated rats ⬇️

scientific article published on 01 March 1969

Changes in certain kinetic properties of hepatic microsomal aniline hydroxylase and ethylmorphine demethylase associated with postnatal development and maturation in male rats ⬇️

scientific article published on July 1969

Clara cell damage and inhibition of pulmonary mixed-function oxidase activity by naphthalene

scientific article published on 01 June 1981

Comparative alterations in extrahepatic drug metabolism by factors known to affect hepatic activity ⬇️

scientific article published on April 15, 1977

Comparison of in vitro drug metabolism by lung, liver, and kidney of several common laboratory species ⬇️

scientific article published on July 1, 1975

Differential effects of anthracycline drugs on rat heart and liver microsomal reduced nicotinamide adenine dinucleotide phosphate-dependent lipid peroxidation

scientific article published on 01 September 1982

Distribution and disposition of platinum following intravenous administration of cis-diamminedichloroplatinum(II) (NSC 119875) to dogs ⬇️

scientific article published on 01 July 1976

Distribution of 14C-lomustine (14C-CCNU)-derived radioactivity following intravenous administration of three potential clinical formulations to rabbits

scientific article published on 01 November 1974

Drug metabolism by microsomes from extrahepatic organs of rat and rabbit prepared by calcium aggregation

scientific article published in September 1975

Effect of Strain Differences and Tumor Presence on Microsomal Drug Metabolism in the Guinea Pig: Brief Communication ⬇️

scientific article published on December 1, 1977

Effect of drug substrates on the reduction of hepatic microsomal cytochrome P-450 by NADPH

scientific article published on 01 May 1968

Effect of partial hepatectomy on the responsiveness of microsomal enzymes and cytochrome P-450 to phenobarbital or 3-methylcholanthrene ⬇️

scientific article

Effect of storage on microsomal mixed function oxidase activity in mouse liver

scientific article published on 01 September 1974

Effect of temperature on the relationship between hepatic microsomal cytochrome P-450 reduction and ethylmorphine demethylation

scientific article

Effect of whole-body hyperthermia on the disposition and metabolism of adriamycin in rabbits ⬇️

scientific article published on 01 May 1978

Effects of activators in vitro on rabbit lung and liver microsomal UDP-glucuronyltransferase activity

scientific article published on 01 September 1975

Effects of dietary ascorbic acid supplementation on hepatic drug-metabolizing enzymes in the guinea pig ⬇️

scientific article published on November 1, 1977

Enhancement of rat heart microsomal lipid peroxidation following doxorubicin treatment in vivo

scientific article published on 01 July 1983

Enhancement of reactive oxygen-dependent mitochondrial membrane lipid peroxidation by the anticancer drug adriamycin

scientific article published on 01 March 1985

Enzymatic conjugation of foreign chemical compounds by rabbit lung and liver

scientific article published on 01 May 1974

Enzymic and biochemical composition of smooth and rough microsomal membranes from monkey, guinea pig and mouse liver

scientific article published in July 1971

Further studies on the submicrosomal distribution of drug-metabolizing components in liver. Localization in fractions of smooth microsomes

scientific article

Hepatic Ethylmorphine Demethylase and A4-Steroid Reductase in the Androgen-Insensitive Pseudohermaphroditic Rat ⬇️

scientific article published on 01 June 1971

Hepatic cytochrome P-450-dependent metabolism and enzymatic conjugation of foreign compounds in vitamin A-deficient rats

scientific article published on 01 January 1980

Improved therapeutic index of bleomycin when administered by continuous infusion in mice

scientific article published on December 1, 1978

In vitro drug metabolism in male and female athymic, nude mice

scientific article published in May 1978

In vitro stimulation by paraquat of reactive oxygen-mediated lipid peroxidation in rat lung microsomes ⬇️

scientific article published on September 15, 1981

Interaction of the oncolytic drug, 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea with the mixed-function oxidase system in rats

scientific article published on 01 April 1984

Kinetics and inelastic light-scattering studies of the role of phospholipids in the microsomal membrane structure

scientific article published on 01 January 1973

Lack of correlation between cortisol-induced precocious maturation of the fetal rabbit lung and drug metabolism ⬇️

scientific article published on March 1, 1979

Lung-selective impairment of cytochrome P-450-dependent monooxygenases and cellular injury by 1,1-dichloroethylene in mice

scientific article published on 01 January 1983

Mechanism of chloramphenicol prevention of carbon tetrachloride-induced liver damage

scientific article published on 01 June 1978

Metabolism and biliary excretion of sulfobromophthalein in vitamin A deficiency

scientific article published on 01 October 1980

Microsomal drug-metabolizing enzyme activity in livers of bats

scientific article

Protection by methylprednisolone against butylated hydroxytoluene-induced pulmonary damage and impairment of microsomal monooxygenase activities in the mouse: lack of effect on fibrosis

scientific article published on 01 January 1986

Pulmonary accumulation of drugs in vitamin A deficiency

scientific article published on 01 January 1980

Quantification of bleomycin pulmonary toxicity in mice by changes in lung hydroxyproline content and morphometric histopathology

scientific article published on March 1978

Relative pulmonary toxicity and antitumor effects of two new bleomycin analogs, pepleomycin and tallysomycin A

scientific article published on 01 April 1980

Selective damage to nonciliated bronchiolar epithelial cells in relation to impairment of pulmonary monooxygenase activities by 1,1-dichloroethylene in mice

scientific article published on 01 June 1984

Sex differences in the uptake and retention of imipramine and desmethylimipramine in the rat lung

scientific article published on 01 March 1982

Sex-dependent differences in the effects of portacaval anastomosis on hepatic monooxygenases in rats

scientific article published on 01 February 1982

Species and dose differences in the accumulation of imipramine by mammalian lungs ⬇️

scientific article published on July 1, 1981

Stimulation by adriamycin of rat heart and liver microsomal NADPH-dependent lipid peroxidation

scientific article published on 01 October 1981

Stimulation of mouse heart and liver microsomal lipid peroxidation by anthracycline anticancer drugs: characterization and effects of reactive oxygen scavengers

scientific article published on 01 September 1983

Studies of hepatic microsomal enzymes, serum proteins, and serum cholesterol after treatment of rats with L-asparaginase alone or in combination with phenobarbital

scientific article published in October 1970

Studies on the in vitro interaction of mitomycin C, nitrofurantoin and paraquat with pulmonary microsomes. Stimulation of reactive oxygen-dependent lipid peroxidation

scientific article published on 01 March 1982

Studies on the interaction of bleomycin A2 with rat lung microsomes. I. Characterization of factors which influence bleomycin-mediated DNA chain breakage ⬇️

scientific article published on 01 April 1982

Studies on the interaction of bleomycin A2 with rat lung microsomes. II. Involvement of adventitious iron and reactive oxygen in bleomycin-mediated DNA chain breakage.

scientific article published in April 1982

Studies on the rate of reduction of hepatic microsomal cytochrome P-450 by reduced nicotinamide adenine dinucleotide phosphate: effect of drug substrates.

scientific article

Studies on the role of protein syntheis in cell injury by toxic agents: I. Effect of cycloheximide administration on several factors modulating carbon tetrachloride-induced liver necrosis

scientific article published in August 1977

Submicrosomal distribution of hepatic drug-metabolizing components in the Gunn rat

scientific article published on 01 January 1973

The distribution of 14C-imipramine in mice bearing lewis lung carcinoma ⬇️

scientific article published on November 19, 1979

The distribution of the components of mixed-function oxidase between the rough and the smooth endoplasmic reticulum of liver cells

scientific article published on December 1968

The effect of chlorpromazine on the uptake and efflux of paraquat in rat lung slices ⬇️

scientific article published on September 30, 1979

The effect of starvation on the kinetics of drug oxidation by hepatic microsomal enzymes from male and female rats ⬇️

scientific article published on October 1, 1970

The effect of unilateral pneumonectomy on in vitro drug metabolism by the contralateral lung of rabbits ⬇️

scientific article published on July 1, 1979

The effect of vitamin A deficiency on hepatic, renal and pulmonary glutathione S-transferase activities in the rat.

scientific article published on June 1980

The effects of adriamycin in vitro and in vivo on hepatic microsomal drug-metabolizing enzymes: Role of microsomal lipid peroxidation ⬇️

scientific article published on 01 December 1981

The effects of ascorbic acid deficiency and repletion on pulmonary, renal, and hepatic drug metabolism in the guinea pig ⬇️

scientific article published on March 1, 1977

The effects of α-tocopherol on the toxicity, disposition, and metabolism of adriamycin in mice ⬇️

scientific article published on June 15, 1979

The kinetics of 32P incorporation into the phospholipids of hepatic rough and smooth microsomal membranes of male and female rats

scientific article

Uptake and efflux of 14C-paraquat by rat lung slices: The effect of imipramine and other drugs ⬇️

scientific article published on July 1, 1979

Vehicle alteration of paraquat lethality in mice ⬇️

scientific article published on May 1, 1979

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