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List of works by Jacques Grosset

A postgenomic method for predicting essential genes at subsaturation levels of mutagenesis: application to Mycobacterium tuberculosis

scientific article

A reader's guide to the bactericidal activity of pyrazinamide and clofazimine alone and in combinations with pretomanid and bedaquiline.

scientific article published in April 2015

Accelerated detection of Mycobacterium tuberculosis genes essential for bacterial survival in guinea pigs, compared with mice

scientific article published on 23 April 2007

Accelerated detection of mycolactone production and response to antibiotic treatment in a mouse model of Mycobacterium ulcerans disease

scientific article (publication date: 2014)

Activities of rifampin, Rifapentine and clarithromycin alone and in combination against mycobacterium ulcerans disease in mice

scientific article

Activity of 5-chloro-pyrazinamide in mice infected with Mycobacterium tuberculosis or Mycobacterium bovis

scientific article published on November 2012

Activity of the fluoroquinolone DC-159a in the initial and continuation phases of treatment of murine tuberculosis

scientific article

Addition of PNU-100480 to first-line drugs shortens the time needed to cure murine tuberculosis.

scientific article

An enhanced regimen as post-exposure chemoprophylaxis for leprosy: PEP+

scientific article published on 05 October 2018

Antibiotics. Targeting DnaN for tuberculosis therapy using novel griselimycins

scientific article

Assessment of clofazimine activity in a second-line regimen for tuberculosis in mice.

scientific article published on September 2013

BCG-mediated protection against Mycobacterium ulcerans infection in the mouse

scientific article

Bactericidal activity does not predict sterilizing activity: the case of rifapentine in the murine model of Mycobacterium ulcerans disease

scientific article

Bactericidal activity of increasing daily and weekly doses of moxifloxacin in murine tuberculosis

scientific article

Bactericidal activity of rifampin-amikacin against Mycobacterium ulcerans in mice

scientific article

Benzothiazinones kill Mycobacterium tuberculosis by blocking arabinan synthesis

scientific journal article

Biphasic kill curve of isoniazid reveals the presence of drug-tolerant, not drug-resistant, Mycobacterium tuberculosis in the guinea pig.

scientific article

C-reactive protein as a screening test for HIV-associated pulmonary tuberculosis prior to antiretroviral therapy in South Africa

scientific article published on 01 August 2018

Characterization of mouse models of Mycobacterium avium complex infection and evaluation of drug combinations

scientific article

Clofazimine Contributes Sustained Antimicrobial Activity after Treatment Cessation in a Mouse Model of Tuberculosis Chemotherapy.

scientific article published on 29 February 2016

Clofazimine has delayed antimicrobial activity against Mycobacterium tuberculosis both in vitro and in vivo.

scientific article published on 25 October 2016

Clofazimine shortens the duration of the first-line treatment regimen for experimental chemotherapy of tuberculosis

scientific article

Combination chemotherapy with the nitroimidazopyran PA-824 and first-line drugs in a murine model of tuberculosis

scientific article

Comparison of the 'Denver regimen' against acute tuberculosis in the mouse and guinea pig.

scientific article

Contribution of moxifloxacin or levofloxacin in second-line regimens with or without continuation of pyrazinamide in murine tuberculosis

scientific article published on July 2013

Daily dosing of rifapentine cures tuberculosis in three months or less in the murine model

scientific article

Dormancy phenotype displayed by extracellular Mycobacterium tuberculosis within artificial granulomas in mice

scientific article

Dose-dependent activity of pyrazinamide in animal models of intracellular and extracellular tuberculosis infections.

scientific article

Dose-ranging activity of the newly registered antituberculosis drug bedaquiline (TMC207)

scientific article published on 01 July 2013

Dose-ranging comparison of rifampin and rifapentine in two pathologically distinct murine models of tuberculosis

scientific article

Effectiveness of tuberculosis chemotherapy correlates with resistance to Mycobacterium tuberculosis infection in animal models

scientific article

Efficacy of Rifampin Plus Clofazimine in a Murine Model of Mycobacterium ulcerans Disease

scientific article

Emergence of fluoroquinolone resistance in Mycobacterium tuberculosis during continuously dosed moxifloxacin monotherapy in a mouse model

scientific article

Enhanced bactericidal activity of rifampin and/or pyrazinamide when combined with PA-824 in a murine model of tuberculosis

scientific article published on 11 August 2008

Evaluation of new antituberculosis drugs in mouse models

scientific article published on January 2007

Evolution of Extensively Drug-Resistant Tuberculosis over Four Decades: Whole Genome Sequencing and Dating Analysis of Mycobacterium tuberculosis Isolates from KwaZulu-Natal

scientific article (publication date: September 2015)

Evolution of extensively drug-resistant tuberculosis over four decades revealed by whole genome sequencing of Mycobacterium tuberculosis from KwaZulu-Natal, South Africa

scholarly article by Keira A. Cohen et al published March 2015 in International journal of mycobacteriology

Fluoroquinolones, tuberculosis, and resistance

scientific article

Genomic and functional analyses of Mycobacterium tuberculosis strains implicate ald in D-cycloserine resistance.

scientific article published on 11 April 2016

Harnessing the full sterilising activity of rifamycins

scientific article published on 01 April 2011

High-Dose Rifamycins Enable Shorter Oral Treatment in a Murine Model of Mycobacterium ulcerans Disease

scientific article published on 29 January 2019

Impact of Clofazimine Dosing on Treatment-Shortening of the First-Line Regimen in a Mouse Model of Tuberculosis.

scientific article published on 7 May 2018

Improving existing tools for Mycobacterium xenopi treatment: assessment of drug combinations and characterization of mouse models of infection and chemotherapy.

scientific article published on 5 November 2012

In vivo validation of the mutant selection window hypothesis with moxifloxacin in a murine model of tuberculosis

scientific article

Isoniazid or moxifloxacin in rifapentine-based regimens for experimental tuberculosis?

scientific article published on 21 August 2008

Latent tuberculosis infection

scientific article published on June 2004

Methionine aminopeptidases from Mycobacterium tuberculosis as novel antimycobacterial targets

scientific article

Microbiological, histological, immunological, and toxin response to antibiotic treatment in the mouse model of Mycobacterium ulcerans disease

scientific article

Modeling early bactericidal activity in murine tuberculosis provides insights into the activity of isoniazid and pyrazinamide

scientific article

Modeling in vivo pharmacokinetics and pharmacodynamics of moxifloxacin therapy for Mycobacterium tuberculosis infection by using a novel cartridge system

scientific article published on February 2005

Moxifloxacin-containing Regimen Greatly Reduces Time to Culture Conversion in Murine Tuberculosis ⬇️

scientific article published on October 24, 2003

Moxifloxacin-containing regimens of reduced duration produce a stable cure in murine tuberculosis

scientific article

Murine model to study the invasion and survival of Mycobacterium tuberculosis in the central nervous system

scientific journal article

Mutations in pepQ Confer Low-Level Resistance to Bedaquiline and Clofazimine in Mycobacterium tuberculosis

scientific article published on 16 May 2016

Mycobacterium tuberculosis in the Extracellular Compartment: an Underestimated Adversary

scientific article

New drugs for tuberculosis treatment

scientific article published on March 2011

Oxazolidinones Can Replace Clarithromycin in Combination with Rifampin in a Mouse Model of Buruli Ulcer

scientific article published on 26 February 2019

PA-824 Exhibits Time-Dependent Activity in a Murine Model of Tuberculosis ⬇️

scientific article published on October 11, 2010

Paradoxical effect of isoniazid on the activity of rifampin-pyrazinamide combination in a mouse model of tuberculosis

scientific article published on 20 July 2009

Pharmacokinetics and pharmacodynamics of clofazimine in a mouse model of tuberculosis

scientific article published on 9 March 2015

Potent twice-weekly rifapentine-containing regimens in murine tuberculosis

scientific article published on 30 March 2006

Powerful bactericidal and sterilizing activity of a regimen containing PA-824, moxifloxacin, and pyrazinamide in a murine model of tuberculosis

scientific article published on 19 February 2008

Promising clinical efficacy of streptomycin-rifampin combination for treatment of buruli ulcer (Mycobacterium ulcerans disease)

scientific article

Rapid assessment of antibacterial activity against Mycobacterium ulcerans by using recombinant luminescent strains

scientific article

Rapid, serial, non-invasive assessment of drug efficacy in mice with autoluminescent Mycobacterium ulcerans infection

scientific article (publication date: 2013)

Reply to "Contradictory results with high-dosage rifamycin in mice and humans".

scientific article published on February 2013

Revisiting Anti-tuberculosis Activity of Pyrazinamide in Mice

scientific article

Rifampicin and clarithromycin (extended release) versus rifampicin and streptomycin for limited Buruli ulcer lesions: a randomised, open-label, non-inferiority phase 3 trial

scientific article published on 12 March 2020

Rifapentine is not more active than rifampin against chronic tuberculosis in guinea pigs

scientific article

Rifapentine, moxifloxacin, or DNA vaccine improves treatment of latent tuberculosis in a mouse model

scientific article published on 8 September 2005

Role of the dosR-dosS two-component regulatory system in Mycobacterium tuberculosis virulence in three animal models.

scientific article published on 22 December 2008

Short-course therapy with daily rifapentine in a murine model of latent tuberculosis infection

scientific article published on 03 September 2009

Shorter-course treatment for Mycobacterium ulcerans disease with high-dose rifamycins and clofazimine in a mouse model of Buruli ulcer

scientific article published on 13 August 2018

Substitution of moxifloxacin for isoniazid during intensive phase treatment of pulmonary tuberculosis.

scientific article published on 30 April 2009

The chemotherapy of leprosy: an interpretive history

scientific article

The impact of mouse passaging of Mycobacterium tuberculosis strains prior to virulence testing in the mouse and guinea pig aerosol models

scientific article

The potent bactericidal activity of streptomycin in the guinea pig model of tuberculosis ceases due to the presence of persisters ⬇️

scientific article published on August 6, 2010

Treating Mycobacterium ulcerans disease (Buruli ulcer): from surgery to antibiotics, is the pill mightier than the knife?

scientific article published on October 2011

Treatment of tuberculosis and optimal dosing schedules

scientific article published on 17 December 2010

Treatment of tuberculosis with rifamycin-containing regimens in immune-deficient mice

scientific article

Treatment-Shortening Effect of a Novel Regimen Combining Clofazimine and High-Dose Rifapentine in Pathologically Distinct Mouse Models of Tuberculosis

scientific article published on 24 May 2019

Using Bioluminescence To Monitor Treatment Response in Real Time in Mice with Mycobacterium ulcerans Infection ⬇️

scientific article published on November 15, 2010

Weekly moxifloxacin and rifapentine is more active than the denver regimen in murine tuberculosis

scientific article published on September 2005

[World epidemiology of tuberculosis and resistance against anti-tuberculosis drugs].

scientific article

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