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List of works by Blanka Říhová

Antitumor activity of IL-2/anti-IL-2 mAb immunocomplexes exerts synergism with that of N-(2-hydroxypropyl)methacrylamide copolymer-bound doxorubicin conjugate due to its low immunosuppressive activity

scientific article published on 13 April 2011

Biocompatibility of N-(2-hydroxypropyl) methacrylamide copolymers containing adriamycin. Immunogenicity, and effect on haematopoietic stem cells in bone marrow in vivo and mouse splenocytes and human peripheral blood lymphocytes in vitro

scientific article published on 01 July 1989

Biological evaluation of polymeric micelles with covalently bound doxorubicin

scientific article published on 01 November 2009

Bloodstream Stability Predetermines the Antitumor Efficacy of Micellar Polymer-Doxorubicin Drug Conjugates with pH-Triggered Drug Release

scientific article published on 21 March 2018

Cancer-associated fibroblasts are not formed from cancer cells by epithelial-to-mesenchymal transition in nu/nu mice

article published in 2014

Chemotherapy based on HPMA copolymer conjugates with pH-controlled release of doxorubicin triggers anti-tumor immunity

scientific article published on 2 November 2005

Chimera of IL-2 linked to light chain of anti-IL-2 mAb mimics IL-2/anti-IL-2 mAb complexes both structurally and functionally.

scientific article published on 5 March 2013

Clinical experience with anthracycline antibiotics-HPMA copolymer-human immunoglobulin conjugates

scientific article published on 12 August 2009

Colorectal cancer patients show decrease in cellular immunity and enhanced plasma level of transforming growth factor – beta and vascular endothelial growth factor (VEGF).

scientific article

Czech Immunological Society (CIS): Immunological "enthusiasm" that began in the 1950s and 60s.

scientific article published in July 2012

Dimerization of an immunoactivating peptide derived from mycobacterial hsp65 using N-hydroxysuccinimide based bifunctional reagents is critical for its antitumor properties.

scientific article

Doxorubicin attached to HPMA copolymer via amide bond modifies the glycosylation pattern of EL4 cells

scientific article published on 24 February 2010

Effect of age on antibody responses in low responder C57BL/10ScSn and high responder A/J strains of mice

scientific article published on 01 October 1993

Ellipticine-aimed polymer-conjugated auger electron emitter: multistage organelle targeting approach.

scientific article published on 4 May 2011

Establishment of imageable model of T-cell lymphoma growing in syngenic mice

scientific article

Fine needle aspiration biopsy proves increased T-lymphocyte proliferation in tumor and decreased metastatic infiltration after treatment with doxorubicin bound to PHPMA copolymer carrier

scientific article published on 26 April 2013

HPMA copolymer-bound doxorubicin induces immunogenic tumor cell death

scientific article published on January 2013

High level of Tregs is a positive prognostic marker in patients with HPV-positive oral and oropharyngeal squamous cell carcinomas.

scientific article

History of Immuno-therapy -  from Coley Toxins to Check-points of the Immune Reaction

scientific article

Immunocompatibility evaluation of hydrogel-coated polyimide implants for applications in regenerative medicine

scientific article published on 30 July 2013

Immunological problems of polymer-bound drugs.

scientific article published on January 1985

Implantation of ultrathin, biofunctionalized polyimide membranes into the subretinal space of rats.

scientific article

In vivo expansion of activated naive CD8+ T cells and NK cells driven by complexes of IL-2 and anti-IL-2 monoclonal antibody as novel approach of cancer immunotherapy

scientific article published on October 2009

Induction of systemic antitumour resistance with targeted polymers

scientific article

Novel IL-2-Poly(HPMA)Nanoconjugate Based Immunotherapy

scientific article published in September 2015

Novel star HPMA-based polymer conjugates for passive targeting to solid tumors

scientific article published on 06 October 2011

Overcoming immunoescape mechanisms of BCL1 leukemia and induction of CD8+ T-cell-mediated BCL1-specific resistance in mice cured by targeted polymer-bound doxorubicin

scientific article published on 01 December 2008

Overcoming multidrug resistance via simultaneous delivery of cytostatic drug and P-glycoprotein inhibitor to cancer cells by HPMA copolymer conjugate

scientific article published on 12 November 2016

Polymer carriers for anticancer drugs targeted to EGF receptor

scientific article

Polymer conjugates of the highly potent cytostatic drug 2-pyrrolinodoxorubicin ⬇️

scientific article published on November 12, 2010

Polymer donors of nitric oxide improve the treatment of experimental solid tumours with nanosized polymer therapeutics

scientific article published on 07 August 2017

Polymer inhibitors of ABC transporter overcoming multidrug resistance: Synthesis, characterization and in vitro evaluation.

scientific article published on 19 August 2015

Polymer nanomedicines based on micelle-forming amphiphilic or water-soluble polymer-doxorubicin conjugates: Comparative study of in vitro and in vivo properties related to the polymer carrier structure, composition, and hydrodynamic properties

scientific article published on 03 March 2020

Polymer therapeutics - Sixth International Symposium: from laboratory to clinical practice.

scientific article published in February 2004

Polymeric anticancer drugs with pH-controlled activation

scientific article published on June 2004

Preclinical evaluation of linear HPMA-doxorubicin conjugates with pH-sensitive drug release: efficacy, safety, and immunomodulating activity in murine model

scientific article

Regulatory T cells and their prognostic value for patients with squamous cell carcinoma of the head and neck

scientific article published on 14 January 2009

SYNTHETIC POLYMER MATRICES FOR NEURAL CELL TRANSPLANTATION.

scientific article published in May 1993

Surface Modification of Polyimide Sheets for Regenerative Medicine Applications ⬇️

scientific article published on October 11, 2010

Synergistic effect of EMF-BEMER-type pulsed weak electromagnetic field and HPMA-bound doxorubicin on mouse EL4 T-cell lymphoma

scientific article published on 10 October 2011

The comparison of in vivo properties of water-soluble HPMA-based polymer conjugates with doxorubicin prepared by controlled RAFT or free radical polymerization.

scientific article published in January 2015

The effects of 5-fluorouracil on immunocompetent cells depend on the genotype of experimental animals used

scientific article published on 01 May 1988

The structure of polymer carriers controls the efficacy of the experimental combination treatment of tumors with HPMA copolymer conjugates carrying doxorubicin and docetaxel

scientific article published on 6 December 2016

The structure-dependent toxicity, pharmacokinetics and anti-tumour activity of HPMA copolymer conjugates in the treatment of solid tumours and leukaemia.

scientific article published on 18 December 2015

Thermoresponsive, hydrolytically degradable polymer micelles intended for radionuclide delivery.

scientific article published in October 2009

Treatment with HPMA copolymer-based doxorubicin conjugate containing human immunoglobulin induces long-lasting systemic anti-tumour immunity in mice.

scientific article published on 25 April 2006

[Escape Strategies of Tumors from Immune Surveillence]

scientific article published on 01 January 2015

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