List of works - Antoni Cortés

A hybrid indoloquinolizidine peptide as allosteric modulator of dopamine D1 receptors

scientific article

A solid-phase combinatorial approach for indoloquinolizidine-peptides with high affinity at D(1) and D(2) dopamine receptors.

scientific article published on 28 April 2015

A2A adenosine receptor ligand binding and signalling is allosterically modulated by adenosine deaminase

scientific article published in May 2011

Adenosine A2A receptor-antagonist/dopamine D2 receptor-agonist bivalent ligands as pharmacological tools to detect A2A-D2 receptor heteromers

scientific article published in September 2009

Allosteric interactions between agonists and antagonists within the adenosine A2A receptor-dopamine D2 receptor heterotetramer

scientific article

Basic concepts in G-protein-coupled receptor homo- and heterodimerization.

scientific article published on 2 November 2007

Biased G Protein-Independent Signaling of Dopamine D1-D3 Receptor Heteromers in the Nucleus Accumbens

scientific article published on 27 March 2019

Biotin ergopeptide probes for dopamine receptors

scientific article

Cannabinoid receptors CB1 and CB2 form functional heteromers in brain

scientific article published on 24 April 2012

Circadian-related heteromerization of adrenergic and dopamine D₄ receptors modulates melatonin synthesis and release in the pineal gland

scientific article

Cocaine disrupts histamine H3 receptor modulation of dopamine D1 receptor signaling: σ1-D1-H3 receptor complexes as key targets for reducing cocaine's effects.

scientific article published on March 2014

Cocaine inhibits dopamine D2 receptor signaling via sigma-1-D2 receptor heteromers

scientific article

Cross-communication between Gi and Gs in a G-protein-coupled receptor heterotetramer guided by a receptor C-terminal domain.

scientific article published on 28 February 2018

Design of a True Bivalent Ligand with Picomolar Binding Affinity for a G Protein-Coupled Receptor Homodimer

scholarly article by Daniel Pulido et al published 26 September 2018 in Journal of Medicinal Chemistry

Detection of heteromerization of more than two proteins by sequential BRET-FRET.

scientific article

Detection of heteromers formed by cannabinoid CB1, dopamine D2, and adenosine A2A G-protein-coupled receptors by combining bimolecular fluorescence complementation and bioluminescence energy transfer.

scientific article

Detection of receptor heteromers involving dopamine receptors by the sequential BRET-FRET technology

scientific article published in January 2013

Direct involvement of sigma-1 receptors in the dopamine D1 receptor-mediated effects of cocaine

scientific article

Dopamine D1-histamine H3 receptor heteromers provide a selective link to MAPK signaling in GABAergic neurons of the direct striatal pathway

scientific article

Effect of several anions on the activity of mitochondrial malate dehydrogenase from pig heart

Evidence for functional pre-coupled complexes of receptor heteromers and adenylyl cyclase.

scientific article published on 28 March 2018

Evidence for the heterotetrameric structure of the adenosine A2A-dopamine D2 receptor complex.

scientific article published on April 2016

Functional selectivity of allosteric interactions within G protein-coupled receptor oligomers: the dopamine D1-D3 receptor heterotetramer.

scientific article

Functional μ-Opioid-Galanin Receptor Heteromers in the Ventral Tegmental Area.

scientific article published on 22 December 2016

G protein-coupled receptor heteromers as new targets for drug development

scientific article published on January 2010

GPCR homomers and heteromers: a better choice as targets for drug development than GPCR monomers?

scientific article published on 05 August 2009

Gi protein coupling to adenosine A1-A2A receptor heteromers in human brain caudate nucleus.

scientific article published on 13 May 2010

Hints on the Lateralization of Dopamine Binding to D1 Receptors in Rat Striatum.

scientific article

Homodimerization of adenosine A₁ receptors in brain cortex explains the biphasic effects of caffeine

scientific article

Human adenosine deaminase as an allosteric modulator of human A(1) adenosine receptor: abolishment of negative cooperativity for [H](R)-pia binding to the caudate nucleus

scientific article

Hypoglycaemia after pancreas transplantation: usefulness of a continuous glucose monitoring system

scientific article published in December 2003

Interactions between calmodulin, adenosine A2A, and dopamine D2 receptors

scientific article

Interactions between intracellular domains as key determinants of the quaternary structure and function of receptor heteromers

scientific article

Intracellular calcium levels determine differential modulation of allosteric interactions within G protein-coupled receptor heteromers.

scientific article published in November 2014

L-DOPA disrupts adenosine A(2A)-cannabinoid CB(1)-dopamine D(2) receptor heteromer cross-talk in the striatum of hemiparkinsonian rats: biochemical and behavioral studies

scientific article published on 9 January 2014

L-DOPA-treatment in primates disrupts the expression of A(2A) adenosine-CB(1) cannabinoid-D(2) dopamine receptor heteromers in the caudate nucleus

scientific article

Marked changes in signal transduction upon heteromerization of dopamine D1 and histamine H3 receptors

scientific article

Modulation of dopamine D1 receptors via histamine H3 receptors is a novel therapeutic target for Huntington's disease

scientific article published on 09 June 2020

Molecular Evidence of Adenosine Deaminase Linking Adenosine A2A Receptor and CD26 Proteins.

scientific article published on 15 February 2018

Moonlighting adenosine deaminase: a target protein for drug development

scientific article

Nature of artifactual bands in the electropherograms of malate dehydrogenase isoenzymes

Old and new ways to calculate the affinity of agonists and antagonists interacting with G-protein-coupled monomeric and dimeric receptors: the receptor-dimer cooperativity index.

scientific article published on 14 June 2007

Psychostimulant pharmacological profile of paraxanthine, the main metabolite of caffeine in humans

scientific article published on 19 December 2012

Quaternary structure of a G-protein-coupled receptor heterotetramer in complex with Gi and Gs.

scientific article

Reinterpreting anomalous competitive binding experiments within G protein-coupled receptor homodimers using a dimer receptor model

scientific article published on 22 November 2018

Striatal pre- and postsynaptic profile of adenosine A(2A) receptor antagonists

scientific article

Targeting the dopamine D3 receptor: an overview of drug design strategies

scientific article

Targeting the receptor-based interactome of the dopamine D1 receptor: looking for heteromer-selective drugs

scientific article published on 11 September 2019

The catalytic site structural gate of adenosine deaminase allosterically modulates ligand binding to adenosine receptors

scientific article published on 27 November 2012

The heterotetrameric structure of the adenosine A1-dopamine D1 receptor complex: Pharmacological implication for restless legs syndrome

scientific article published on 13 February 2019

The two-state dimer receptor model: a general model for receptor dimers

scientific article published on 24 February 2006

Useful pharmacological parameters for G-protein-coupled receptor homodimers obtained from competition experiments. Agonist-antagonist binding modulation.

scientific article published on 28 July 2009

α2A- and α2C-Adrenoceptors as Potential Targets for Dopamine and Dopamine Receptor Ligands

scientific article published on 18 March 2018

List of works by Antoni Cortés

A hybrid indoloquinolizidine peptide as allosteric modulator of dopamine D1 receptors

A solid-phase combinatorial approach for indoloquinolizidine-peptides with high affinity at D(1) and D(2) dopamine receptors.

A2A adenosine receptor ligand binding and signalling is allosterically modulated by adenosine deaminase

Adenosine A2A receptor-antagonist/dopamine D2 receptor-agonist bivalent ligands as pharmacological tools to detect A2A-D2 receptor heteromers

Allosteric interactions between agonists and antagonists within the adenosine A2A receptor-dopamine D2 receptor heterotetramer

Basic concepts in G-protein-coupled receptor homo- and heterodimerization.

Biased G Protein-Independent Signaling of Dopamine D1-D3 Receptor Heteromers in the Nucleus Accumbens

Biotin ergopeptide probes for dopamine receptors

Cannabinoid receptors CB1 and CB2 form functional heteromers in brain

Circadian-related heteromerization of adrenergic and dopamine D₄ receptors modulates melatonin synthesis and release in the pineal gland

Cocaine disrupts histamine H3 receptor modulation of dopamine D1 receptor signaling: σ1-D1-H3 receptor complexes as key targets for reducing cocaine's effects.

Cocaine inhibits dopamine D2 receptor signaling via sigma-1-D2 receptor heteromers

Cross-communication between Gi and Gs in a G-protein-coupled receptor heterotetramer guided by a receptor C-terminal domain.

Design of a True Bivalent Ligand with Picomolar Binding Affinity for a G Protein-Coupled Receptor Homodimer

Detection of heteromerization of more than two proteins by sequential BRET-FRET.

Detection of heteromers formed by cannabinoid CB1, dopamine D2, and adenosine A2A G-protein-coupled receptors by combining bimolecular fluorescence complementation and bioluminescence energy transfer.

Detection of receptor heteromers involving dopamine receptors by the sequential BRET-FRET technology

Direct involvement of sigma-1 receptors in the dopamine D1 receptor-mediated effects of cocaine

Dopamine D1-histamine H3 receptor heteromers provide a selective link to MAPK signaling in GABAergic neurons of the direct striatal pathway

Effect of several anions on the activity of mitochondrial malate dehydrogenase from pig heart

Evidence for functional pre-coupled complexes of receptor heteromers and adenylyl cyclase.

Evidence for the heterotetrameric structure of the adenosine A2A-dopamine D2 receptor complex.

Functional selectivity of allosteric interactions within G protein-coupled receptor oligomers: the dopamine D1-D3 receptor heterotetramer.

Functional μ-Opioid-Galanin Receptor Heteromers in the Ventral Tegmental Area.

G protein-coupled receptor heteromers as new targets for drug development

GPCR homomers and heteromers: a better choice as targets for drug development than GPCR monomers?

Gi protein coupling to adenosine A1-A2A receptor heteromers in human brain caudate nucleus.

Hints on the Lateralization of Dopamine Binding to D1 Receptors in Rat Striatum.

Homodimerization of adenosine A₁ receptors in brain cortex explains the biphasic effects of caffeine

Human adenosine deaminase as an allosteric modulator of human A(1) adenosine receptor: abolishment of negative cooperativity for [H](R)-pia binding to the caudate nucleus

Hypoglycaemia after pancreas transplantation: usefulness of a continuous glucose monitoring system

Interactions between calmodulin, adenosine A2A, and dopamine D2 receptors

Interactions between intracellular domains as key determinants of the quaternary structure and function of receptor heteromers

Intracellular calcium levels determine differential modulation of allosteric interactions within G protein-coupled receptor heteromers.

L-DOPA disrupts adenosine A(2A)-cannabinoid CB(1)-dopamine D(2) receptor heteromer cross-talk in the striatum of hemiparkinsonian rats: biochemical and behavioral studies

L-DOPA-treatment in primates disrupts the expression of A(2A) adenosine-CB(1) cannabinoid-D(2) dopamine receptor heteromers in the caudate nucleus

Marked changes in signal transduction upon heteromerization of dopamine D1 and histamine H3 receptors

Modulation of dopamine D1 receptors via histamine H3 receptors is a novel therapeutic target for Huntington's disease

Molecular Evidence of Adenosine Deaminase Linking Adenosine A2A Receptor and CD26 Proteins.

Moonlighting adenosine deaminase: a target protein for drug development

Nature of artifactual bands in the electropherograms of malate dehydrogenase isoenzymes

Old and new ways to calculate the affinity of agonists and antagonists interacting with G-protein-coupled monomeric and dimeric receptors: the receptor-dimer cooperativity index.

Psychostimulant pharmacological profile of paraxanthine, the main metabolite of caffeine in humans

Quaternary structure of a G-protein-coupled receptor heterotetramer in complex with Gi and Gs.

Reinterpreting anomalous competitive binding experiments within G protein-coupled receptor homodimers using a dimer receptor model

Striatal pre- and postsynaptic profile of adenosine A(2A) receptor antagonists

Targeting the dopamine D3 receptor: an overview of drug design strategies

Targeting the receptor-based interactome of the dopamine D1 receptor: looking for heteromer-selective drugs

The catalytic site structural gate of adenosine deaminase allosterically modulates ligand binding to adenosine receptors

The heterotetrameric structure of the adenosine A1-dopamine D1 receptor complex: Pharmacological implication for restless legs syndrome

The two-state dimer receptor model: a general model for receptor dimers

Useful pharmacological parameters for G-protein-coupled receptor homodimers obtained from competition experiments. Agonist-antagonist binding modulation.

α2A- and α2C-Adrenoceptors as Potential Targets for Dopamine and Dopamine Receptor Ligands