List of works by Jaime A. Escobedo

A PDGF receptor domain essential for mitogenesis but not for many other responses to PDGF.

scientific article published in September 1988

A common PDGF receptor is activated by homodimeric A and B forms of PDGF

scientific article

A phosphatidylinositol-3 kinase binds to platelet-derived growth factor receptors through a specific receptor sequence containing phosphotyrosine ⬇️

scientific article published on February 1, 1991

A region of the 85-kilodalton (kDa) subunit of phosphatidylinositol 3-kinase binds the 110-kDa catalytic subunit in vivo

scientific article

Activation of Na+/H+ exchange by platelet-derived growth factor involves phosphatidylinositol 3'-kinase and phospholipase C gamma

scientific article published in December 1994

Biosynthetic and glycosylation studies of cell surface platelet-derived growth factor receptors.

scientific article

Cardiac myocyte hypertrophy is associated with c-myc protooncogene expression

scientific article

Characterization of a new member of the TNF family expressed on antigen presenting cells

scientific article (publication date: December 1999)

Chromosomal localization of the gene for AA-type platelet-derived growth factor receptor (PDGFRA) in humans and mice ⬇️

scientific article published on January 1, 1991

Direct activation of the serine/threonine kinase activity of Raf-1 through tyrosine phosphorylation by the PDGF beta-receptor

scientific article published on August 1989

Distinct phosphotyrosines on a growth factor receptor bind to specific molecules that mediate different signaling pathways

scientific article (publication date: May 1992)

Dominant-negative mutations of platelet-derived growth factor (PDGF) receptors. Inhibition of receptor function by ligand-dependent formation of heterodimers between PDGF alpha- and beta-receptors.

scientific article published on October 1993

Elevated expression of axin2 and hnkd mRNA provides evidence that Wnt/beta -catenin signaling is activated in human colon tumors

scientific article

Evidence for both tyrosine kinase and G-protein-coupled pathways leading to starfish egg activation

scientific article

Identification of Tyr-397 as the primary site of tyrosine phosphorylation and pp60src association in the focal adhesion kinase, pp125FAK.

scientific article published on May 1995

Identification of phosphotyrosine residues during protein sequence analysis

scientific article published in January 1991

Inhibition of PDGF β Receptor Signal Transduction by Coexpression of a Truncated Receptor ⬇️

scientific article published on May 10, 1991

Interactions of Growth Factor Receptors with Cytoplasmic Signaling Molecules ⬇️

scientific article published on January 1, 1991

Interactions of PDGF and FGF receptors with cytoplasmic signaling molecules

scientific article published on January 1, 1992

Ligand activation causes a phosphorylation-dependent change in platelet-derived growth factor receptor conformation

scientific article published on September 1988

Ligand activation causes a phosphorylation-dependent change in platelet-derived growth factor receptor conformation

scientific article published on January 1988

Long-term correction of obesity and diabetes in genetically obese mice by a single intramuscular injection of recombinant adeno-associated virus encoding mouse leptin

scientific article

Modification of the 85-kilodalton subunit of phosphatidylinositol-3 kinase in platelet-derived growth factor-stimulated cells ⬇️

scientific article published on August 1, 1992

Molecular mechanisms of platelet-derived growth factor action

scientific article

Mutations of the platelet-derived growth factor receptor that cause a loss of ligand-induced conformational change, subtle changes in kinase activity, and impaired ability to stimulate DNA synthesis

scientific article published on October 1989

Phosphatidylinositol linkage of a truncated form of the platelet-derived growth factor receptor.

scientific article published in October 1988

Phospholipase C gamma activation, phosphotidylinositol hydrolysis, and calcium mobilization are not required for FGF receptor-mediated chemotaxis.

scientific article published on January 1994

Platelet derived growth factor (PDGF) autocrine components in human tumor cell lines

scientific article published on February 1990

Platelet-derived growth factor receptor mediates activation of ras through different signaling pathways in different cell types

scientific journal article

Platelet-derived growth factor receptors expressed by cDNA transfection couple to a diverse group of cellular responses associated with cell proliferation

scientific article published in January 1988

Platelet-derived growth factor triggers translocation of the insulin-regulatable glucose transporter (type 4) predominantly through phosphatidylinositol 3-kinase binding sites on the receptor

scientific article

Point mutation of an FGF receptor abolishes phosphatidylinositol turnover and Ca2+ flux but not mitogenesis

scientific article published on August 20, 1992

Receptor tyrosine kinase stimulates cell-matrix adhesion by phosphatidylinositol 3 kinase and phospholipase C-gamma 1 pathways

scientific article published on 01 September 1995

Regulation of chemotaxis by the platelet-derived growth factor receptor-beta

scientific article published on February 1994

Role of phosphatidylinositol kinase in PDGF receptor signal transduction

scientific journal article

Role of tyrosine kinase and membrane-spanning domains in signal transduction by the platelet-derived growth factor receptor

scientific article

Signal transduction by the platelet-derived growth factor receptor

scientific article published on January 1988

Structure of the receptor for platelet-derived growth factor helps define a family of closely related growth factor receptors

scientific article (publication date: September 1986)

The C-terminal SH2 domain of p85 accounts for the high affinity and specificity of the binding of phosphatidylinositol 3-kinase to phosphorylated platelet-derived growth factor beta receptor ⬇️

scientific article published on April 1, 1992

The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor

scientific article published on February 21, 1992

The interaction of small domains between the subunits of phosphatidylinositol 3-kinase determines enzyme activity

scientific article published on April 1994

The stimulation of paracrine and autocrine mitogenic pathways by the platelet-derived growth factor receptor

scientific article published on January 1987

Viability of transgenic mice expressing a platelet derived growth factor (PDGF) antagonist in plasma

scientific article published on 01 April 1996

beta-Catenin regulates vascular endothelial growth factor expression in colon cancer

scientific article

cDNA cloning of a Novel 85 kd protein that has SH2 domains and regulates binding of PI3-kinase to the PDGF β-receptor ⬇️

scientific article published on April 5, 1991

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