Search filters

List of works by Leah M. Hesse

Apparent mechanism-based inhibition of human CYP3A in-vitro by lopinavir ⬇️

scientific article published on March 1, 2003

CYP2B6 mediates the in vitro hydroxylation of bupropion: potential drug interactions with other antidepressants.

scientific article

CYP3A4 is the major CYP isoform mediating the in vitro hydroxylation and demethylation of flunitrazepam.

scientific article

Clinically Important Drug Interactions with Zopiclone, Zolpidem and Zaleplon

scientific article published on January 1, 2003

Cytochrome P-450 2B6 is responsible for interindividual variability of propofol hydroxylation by human liver microsomes

scientific article

Effect of age on in vitro triazolam biotransformation in male human liver microsomes

scientific article published on 21 November 2003

Effect of bupropion on CYP2B6 and CYP3A4 catalytic activity, immunoreactive protein and mRNA levels in primary human hepatocytes: comparison with rifampicin

scientific article published in September 2003

Effect of zolpidem on human cytochrome P450 activity, and on transport mediated by P-glycoprotein

scientific article published on December 2002

Evidence for oxazepam as an in vivo probe of UGT2B15: oxazepam clearance is reduced by UGT2B15 D85Y polymorphism but unaffected by UGT2B17 deletion

scientific article

Nicotine glucuronidation and the human UDP-glucuronosyltransferase UGT2B10.

scientific article

Pharmacogenetic determinants of interindividual variability in bupropion hydroxylation by cytochrome P450 2B6 in human liver microsomes

scientific article

Pharmacokinetic properties of zolpidem in elderly and young adults: possible modulation by testosterone in men.

scientific article published in September 2003

Quantitation of CYP2B6, Constitutive Androstane Receptor, and Pregnane X Receptor mRNA levels ⬇️

scientific article published on May 1, 2003

Quantitative distribution of mRNAs encoding the 19 human UDP-glucuronosyltransferase enzymes in 26 adult and 3 fetal tissues

scientific article published on October 13, 2011

Ritonavir has minimal impact on the pharmacokinetic disposition of a single dose of bupropion administered to human volunteers

scientific article published on 01 May 2006

Ritonavir, efavirenz, and nelfinavir inhibit CYP2B6 activity in vitro: potential drug interactions with bupropion

scientific article

UDP glucuronosyltransferase (UGT) 1A6 pharmacogenetics: I. Identification of polymorphisms in the 5'-regulatory and exon 1 regions, and association with human liver UGT1A6 gene expression and glucuronidation

scientific article

UDP glucuronosyltransferase (UGT) 1A6 pharmacogenetics: II. Functional impact of the three most common nonsynonymous UGT1A6 polymorphisms (S7A, T181A, and R184S).

scientific article

Paulina is supported by:

About Paulina

Help