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List of works by Calogera M. Simonaro

Acid ceramidase maintains the chondrogenic phenotype of expanded primary chondrocytes and improves the chondrogenic differentiation of bone marrow-derived mesenchymal stem cells

scientific article

Acid ceramidase treatment enhances the outcome of autologous chondrocyte implantation in a rat osteochondral defect model.

scientific article published on 30 October 2015

Acid sphingomyelinase deficiency: prevalence and characterization of an intermediate phenotype of Niemann-Pick disease

scientific article published on 01 October 2006

Acid sphingomyelinase-deficient Niemann-Pick disease: novel findings in a Greek child.

scientific article

Anti-TNF-alpha therapy enhances the effects of enzyme replacement therapy in rats with mucopolysaccharidosis type VI

scientific article

Articular chondrocytes from animals with a dermatan sulfate storage disease undergo a high rate of apoptosis and release nitric oxide and inflammatory cytokines: a possible mechanism underlying degenerative joint disease in the mucopolysaccharidoses

scientific article published on 01 September 2001

Arylsulfatase B activities and glycosaminoglycan levels in retrovirally transduced mucopolysaccharidosis type VI cells. Prospects for gene therapy

scientific article published on July 1996

Autologous transplantation of retrovirally transduced bone marrow or neonatal blood cells into cats can lead to long-term engraftment in the absence of myeloablation

scientific article published in January 1999

Bone marrow transplantation in newborn rats with mucopolysaccharidosis type VI: biochemical, pathological, and clinical findings

scientific article published on 01 May 1997

Cartilage and chondrocyte pathology in the mucopolysaccharidoses: The role of glycosaminoglycan-mediated inflammation ⬇️

scientific article published on 01 January 2010

Dose responsive effects of subcutaneous pentosan polysulfate injection in mucopolysaccharidosis type VI rats and comparison to oral treatment

scientific article

Efficacy of pentosan polysulfate in in vitro models of lysosomal storage disorders: Fabry and Gaucher Disease

scientific article published on 31 May 2019

Enzyme replacement therapy for Farber disease: Proof-of-concept studies in cells and mice

scientific article published on 13 February 2017

Farber disease is characterized by typical features but a broad phenotypic spectrum: Selected information from a cohort of 37 patients

scientific article published in February 2016

Growth Plate Pathology in the Mucopolysaccharidosis Type VI Rat Model-An Experimental and Computational Approach

scientific article published on 31 May 2020

Identification and characterization of eight novel SMPD1 mutations causing types A and B Niemann-Pick disease

scientific article

Identification and characterization of the molecular lesion causing mucopolysaccharidosis type I in cats

scientific article

Imprinting at the SMPD1 locus: implications for acid sphingomyelinase-deficient Niemann-Pick disease

scientific article

Infusion of recombinant human acid sphingomyelinase into niemann-pick disease mice leads to visceral, but not neurological, correction of the pathophysiology

scientific article published on 01 October 2000

Insertional mutagenesis of the mouse acid ceramidase gene leads to early embryonic lethality in homozygotes and progressive lipid storage disease in heterozygotes

scientific article published in February 2002

Intra-articular enzyme replacement therapy with rhIDUA is safe, well-tolerated, and reduces articular GAG storage in the canine model of mucopolysaccharidosis type I.

scientific article

Involvement of the Toll-like receptor 4 pathway and use of TNF-alpha antagonists for treatment of the mucopolysaccharidoses

scientific article

Joint and bone disease in mucopolysaccharidoses VI and VII: identification of new therapeutic targets and biomarkers using animal models

scientific article published on 3 March 2005

Mechanism of glycosaminoglycan-mediated bone and joint disease: implications for the mucopolysaccharidoses and other connective tissue diseases

scientific article

Mucopolysaccharidosis type VI in rats: isolation of cDNAs encoding arylsulfatase B, chromosomal localization of the gene, and identification of the mutation

scientific journal article

N-acetylgalactosamine-4-sulfatase: identification of four new mutations within the conserved sulfatase region causing mucopolysaccharidosis type VI

scientific article published on 01 December 1995

Oral glycotoxins are a modifiable cause of dementia and the metabolic syndrome in mice and humans

scientific article

Pentosan Polysulfate Treatment of Mucopolysaccharidosis Type IIIA Mice

scientific article published on 14 April 2018

Pentosan Polysulfate: Oral Versus Subcutaneous Injection in Mucopolysaccharidosis Type I Dogs

scientific article

Pentosan polysulfate: a novel therapy for the mucopolysaccharidoses

scientific article (publication date: 2013)

Polyarticular arthritis as presenting feature of farber disease: a lysosomal storage disease involving inflammation.

scientific article published on 17 September 2014

SAT0493 Farber Disease: First Natural History Cohort Demonstrates a Broad Clinical Spectrum with Implications for Juvenile Idiopathic Arthritis Patients

scientific article published in June 2015

Safety Study of Sodium Pentosan Polysulfate for Adult Patients with Mucopolysaccharidosis Type II

scientific article published on 17 December 2019

Structural, compositional, and biomechanical alterations of the lumbar spine in rats with mucopolysaccharidosis type VI (Maroteaux–Lamy syndrome) ⬇️

scientific article published on November 28, 2012

Systemic ceramide accumulation leads to severe and varied pathological consequences.

scientific article published on 16 May 2013

The Genetics of Sphingolipid Hydrolases and Sphingolipid Storage Diseases ⬇️

scientific article published on January 1, 2013

The demographics and distribution of type B Niemann-Pick disease: novel mutations lead to new genotype/phenotype correlations

scientific article published on 04 October 2002

Treatment with pentosan polysulphate in patients with MPS I: results from an open label, randomized, monocentric phase II study

scientific article published on 2 September 2016

Two Siblings with Niemann-Pick Disease (NPD) Type B: Clinical Findings and Novel Mutations of the Acid Sphingomyelinase Gene ⬇️

scientific article published on February 25, 2012

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