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List of works by Efstathios S. Gonos

A novel mitochondrial DNA-like sequence insertion polymorphism in Intron I of the FOXO1A gene

scientific article published in March 2004

Age-dependent expression of DNMT1 and DNMT3B in PBMCs from a large European population enrolled in the MARK-AGE study

scientific article

Aging and longevity between genetic background and lifestyle intervention.

scientific article

Analysis of the machinery and intermediates of the 5hmC-mediated DNA demethylation pathway in aging on samples from the MARK-AGE Study

scientific article published on 29 August 2016

Anti-ageing and rejuvenating effects of quercetin

scientific article published on 7 July 2010

Anti-ageing properties of Khelma Longevity™: treatment of human fibroblasts increases proteasome levels and decreases the levels of oxidized proteins

scientific article published on 5 March 2017

Antioxidants linked with physical, cognitive and psychological frailty: Analysis of candidate biomarkers and markers derived from the MARK-AGE study

scientific article published on 30 April 2018

Associations between Specific Redox Biomarkers and Age in a Large European Cohort: The MARK-AGE Project

scientific article published on 19 July 2017

Beneficial Effects of Elderly Tailored Mediterranean Diet on the Proteasomal Proteolysis.

scientific article published in May 2018

CRM1 Protein-mediated Regulation of Nuclear Clusterin (nCLU), an Ionizing Radiation-stimulated, Bax-dependent Pro-death Factor ⬇️

scientific article published on September 27, 2011

Central role of the proteasome in senescence and survival of human fibroblasts: induction of a senescence-like phenotype upon its inhibition and resistance to stress upon its activation.

scientific article published on 7 May 2003

Chemical analysis of Greek pollen - Antioxidant, antimicrobial and proteasome activation properties.

scientific article

Cloning of differentially expressed genes in skin fibroblasts from centenarians

scientific article

Clusterin/Apolipoprotein J up-regulation after zinc exposure, replicative senescence or differentiation of human haematopoietic cells

Comparative Meta-Analysis of Transcriptomics Data during Cellular Senescence and In Vivo Tissue Ageing

scientific article

Comparative effects of hypoxia on normal and immortalized human diploid fibroblasts

scientific article published on 01 May 2006

Corrigendum to “What evidence is there for the existence of individual genes with antagonistic pleiotropic effects?” [Mechanisms of Ageing and Development 126 (2005) 421–429]

article

Editorial

scientific article published on 14 September 2015

Exposure of human diploid fibroblasts to hypoxia extends proliferative life span

scientific article published on November 2007

Functional analysis of clusterin/apolipoprotein J in cellular death induced by severe genotoxic stress

scientific article published on June 2004

Gender- and age-dependencies of oxidative stress, as detected based on the steady state concentrations of different biomarkers in the MARK-AGE study

scientific article published on 15 April 2019

Genome-wide linkage analysis for human longevity: Genetics of Healthy Aging Study

scientific article published on 06 February 2013

Genome-wide transcriptome profile of the human osteosarcoma Sa OS and U-2 OS cell lines

scientific article

High-resolution quantitative metabolome analysis of urine by automated flow injection NMR.

scientific article published on 29 May 2013

Human mesenchymal stem cells with enhanced telomerase activity acquire resistance against oxidative stress-induced genomic damage.

scientific article

Identification of differentially expressed proteins in senescent human embryonic fibroblasts

scientific article published on 5 October 2005

Lack of consensus on an aging biology paradigm? A global survey reveals an agreement to disagree, and the need for an interdisciplinary framework

scientific article published on 18 July 2020

MARK-AGE biomarkers of ageing

scientific article

MARK-AGE population: From the human model to new insights

scientific article

Medication Intake Is Associated with Lower Plasma Carotenoids and Higher Fat-Soluble Vitamins in the Cross-Sectional MARK-AGE Study in Older Individuals

scientific article published on 01 July 2020

Mediterranean diet and inflammaging in the elderly: the European project NU-AGE. Preface.

scientific article

Micronutrient-gene interactions related to inflammatory/immune response and antioxidant activity in ageing and inflammation. A systematic review

scientific article published on 02 January 2014

Microwave-assisted synthesis of 3,5-disubstituted isoxazoles and evaluation of their anti-ageing activity

scientific article

Nuclear erythroid factor 2-mediated proteasome activation delays senescence in human fibroblasts

scientific article

Optimization of in vitro measurement of proteasome activity in mammalian cells using fluorogenic substrates

scientific article

Origin and pathophysiology of protein carbonylation, nitration and chlorination in age-related brain diseases and aging.

scientific article published in May 2018

Overexpression of apolipoprotein J in human fibroblasts protects against cytotoxicity and premature senescence induced by ethanol and tert-butylhydroperoxide

scientific article published on January 2002

Overexpression of hUMP1/POMP proteasome accessory protein enhances proteasome-mediated antioxidant defence

scientific article

Overexpression of proteasome beta5 assembled subunit increases the amount of proteasome and confers ameliorated response to oxidative stress and higher survival rates

scientific article published on 20 January 2005

Partial proteasome inhibition in human fibroblasts triggers accelerated M1 senescence or M2 crisis depending on p53 and Rb status

scientific article

Pharmacological intervention in a transgenic mouse model improves Alzheimer's-associated pathological phenotype: involvement of proteasome activation

scientific article published on 03 December 2020

Plasma Carotenoids, Tocopherols, and Retinol in the Age-Stratified (35-74 Years) General Population: A Cross-Sectional Study in Six European Countries

scientific article

Prevalence and loads of torquetenovirus (TTV) in the European MARK-AGE Study population

scientific article published on 15 December 2019

Proteasome activation delays aging in vitro and in vivo

scientific article published on 27 March 2014

Proteasome activation enhances stemness and lifespan of human mesenchymal stem cells

scientific article published on 27 December 2016

Proteasome activation: An innovative promising approach for delaying aging and retarding age-related diseases.

scientific article published on 23 December 2014

Proteasome dysfunction in mammalian aging: steps and factors involved

scientific article

Proteasome inhibition induces a senescence-like phenotype in primary human fibroblasts cultures

scientific article published on January 2004

Proteasome response to interferon-gamma is altered in senescent human fibroblasts

scientific article published on 21 June 2006

Protection against Tetanus and Diphtheria in Europe: The impact of age, gender and country of origin based on data from the MARK-AGE Study

scientific article published on 7 October 2017

Protein damage, repair and proteolysis.

scientific article published on 26 October 2012

Protein degradation during aging: the lysosome-, the calpain- and the proteasome-dependent cellular proteolytic systems

scientific article

Protein modification and maintenance systems as biomarkers of ageing.

scientific article

Protein synthesis inhibition induces proteasome assembly and function

scientific article published on 24 April 2019

Quality control data of physiological and immunological biomarkers measured in serum and plasma

scientific article

Reduced expression levels of the senescence biomarker clusterin/apolipoprotein j in lymphocytes from healthy centenarians

scientific article published on 01 May 2006

Report of Society for Free Radical Research Europe Summer School

scientific article published on 01 January 2008

Serum levels of the senescence biomarker clusterin/apolipoprotein J increase significantly in diabetes type II and during development of coronary heart disease or at myocardial infarction

scientific article published on 01 October 2002

Signaling pathways of dietary energy restriction and metabolism on brain physiology and in age-related neurodegenerative diseases

scientific article published on 26 September 2020

Silencing expression of the clusterin/apolipoprotein j gene in human cancer cells using small interfering RNA induces spontaneous apoptosis, reduced growth ability, and cell sensitization to genotoxic and oxidative stress

scientific article published on March 2004

Stress and Senescence: A Special Issue dedicated to Olivier Toussaint

scientific article published in March 2018

The co-occurrence of mtDNA mutations on different oxidative phosphorylation subunits, not detected by haplogroup analysis, affects human longevity and is population specific

scientific article

The conundrum of human immune system "senescence"

scientific article published on 16 September 2020

The genetics of human longevity

scientific article published on May 2006

The olive constituent oleuropein exhibits proteasome stimulatory properties in vitro and confers life span extension of human embryonic fibroblasts

scientific article published on June 2007

The proteasome is an integral part of solar ultraviolet a radiation-induced gene expression

scientific article published on 18 August 2009

Vitamin E-gene interactions in aging and inflammatory age-related diseases: implications for treatment. A systematic review

scientific article published on 11 January 2014

What evidence is there for the existence of individual genes with antagonistic pleiotropic effects?

scientific article

What studies on human longevity tell us about the risk for cancer in the oldest old: data and hypotheses on the genetics and immunology of centenarians

scientific article

Where ageing goes nowadays: Mechanisms, pathways, biomarkers and anti-ageing strategies

scientific article published on 18 December 2018

Zinc, metallothioneins, and longevity--effect of zinc supplementation: zincage study.

scientific article

Zinc-induced Metallothionein in centenarian offspring from a large European population: the MARK-AGE Project

scientific article

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