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List of works by Kimiko Kobayashi

Activation of Src-family kinases in spinal microglia contributes to mechanical hypersensitivity after nerve injury.

scientific article published in August 2006

Activation of extracellular signal-regulated protein kinase in sensory neurons after noxious gastric distention and its involvement in acute visceral pain in rats

scientific article published on 17 January 2008

Activation of extracellular signal-regulated protein kinases 5 in primary afferent neurons contributes to heat and cold hyperalgesia after inflammation

scientific article published on 15 June 2007

Agonist of proteinase-activated receptor 2 increases painful behavior produced by alpha, beta-methylene adenosine 5'-triphosphate

scientific article published on 01 August 2006

Alteration of the cell adhesion molecule L1 expression in a specific subset of primary afferent neurons contributes to neuropathic pain

scientific article (publication date: February 2007)

Antisense knock down of TRPA1, but not TRPM8, alleviates cold hyperalgesia after spinal nerve ligation in rats

scientific article published on 20 March 2006

Axotomy increases plasma membrane Ca2+ pump isoform4 in primary afferent neurons.

scientific article published in January 2007

COX-1-dependent prostaglandin D2 in microglia contributes to neuropathic pain via DP2 receptor in spinal neurons

scientific article published on 18 March 2013

Changes in transient receptor potential channels in the rat geniculate ganglion after chorda tympani nerve injury.

scientific article

Comparative study of the distribution of the alpha-subunits of voltage-gated sodium channels in normal and axotomized rat dorsal root ganglion neurons

scientific article

Differential activation of p38 and extracellular signal-regulated kinase in spinal cord in a model of bee venom-induced inflammation and hyperalgesia

scientific article (publication date: 30 April 2008)

Differential expression of mGluRs in rat spinal dorsal horns and their modulatory effects on nocifensive behaviors

scientific article published on 01 January 2019

Differential expression patterns of mRNAs for P2X receptor subunits in neurochemically characterized dorsal root ganglion neurons in the rat

scientific article published on 01 January 2005

Distinct expression of TRPM8, TRPA1, and TRPV1 mRNAs in rat primary afferent neurons with adelta/c-fibers and colocalization with trk receptors

scientific article published in December 2005

Expression of ATP receptors in the rat dorsal root ganglion and spinal cord

scientific article published on November 20, 2012

Expression of Leukotriene Receptors in the Rat Dorsal Root Ganglion and the Effects on Pain Behaviors

scientific article published on September 17, 2010

Expression of mRNA for four subtypes of the proteinase-activated receptor in rat dorsal root ganglia

scientific article published in April 2005

Frequency-dependent ERK phosphorylation in spinal neurons by electric stimulation of the sciatic nerve and the role in electrophysiological activity

scientific article (publication date: 16 July 2007)

Increase of close homolog of cell adhesion molecule L1 in primary afferent by nerve injury and the contribution to neuropathic pain

scientific article published on 01 June 2011

Induction of the P2X7 receptor in spinal microglia in a neuropathic pain model

scientific article published on September 8, 2011

Inhibition of TRPA1 Channel Activity in Sensory Neurons by the Glial Cell Line-Derived Neurotrophic Factor Family Member, Artemin

scientific article published on May 27, 2011

Intensity-dependent activation of extracellular signal-regulated protein kinase 5 in sensory neurons contributes to pain hypersensitivity

scientific article published on 19 January 2007

Interleukin-18 and its receptor are expressed in gonadotropin-releasing hormone neurons of mouse and rat forebrain

scientific article published on 31 March 2017

Leukotriene enhances NMDA-induced inward currents in dorsal horn neurons of the rat spinal cord after peripheral nerve injury

scientific article published on 9 September 2015

Leukotriene synthases and the receptors induced by peripheral nerve injury in the spinal cord contribute to the generation of neuropathic pain

scientific journal article

Localization of prostaglandin E2 synthases and E-prostanoid receptors in the spinal cord in a rat model of neuropathic pain

scientific article published on 10 October 2020

Macrophage-Colony Stimulating Factor Derived from Injured Primary Afferent Induces Proliferation of Spinal Microglia and Neuropathic Pain in Rats

scientific article

Microglial TNFα Induces COX2 and PGI2 Synthase Expression in Spinal Endothelial Cells during Neuropathic Pain

scientific article

Multiple P2Y subtypes in spinal microglia are involved in neuropathic pain after peripheral nerve injury

scientific article published on June 26, 2012

Negative Regulation of TRPA1 by AMPK in Primary Sensory Neurons as a Potential Mechanism of Painful Diabetic Neuropathy.

scientific article published on 12 October 2017

Neurons and glial cells differentially express P2Y receptor mRNAs in the rat dorsal root ganglion and spinal cord

scientific article published on 01 October 2006

P2Y12 receptor upregulation in activated microglia is a gateway of p38 signaling and neuropathic pain

scientific article published in March 2008

Peripherally increased artemin is a key regulator of TRPA1/V1 expression in primary afferent neurons

scientific article

Phospholipase C and protein kinase A mediate bradykinin sensitization of TRPA1: a molecular mechanism of inflammatory pain.

scientific article published on 20 March 2008

Phosphorylation of ezrin/radixin/moesin (ERM) protein in spinal microglia following peripheral nerve injury and lysophosphatidic acid administration

scientific article published on October 12, 2012

Possible involvement of P2Y2 metabotropic receptors in ATP-induced transient receptor potential vanilloid receptor 1-mediated thermal hypersensitivity.

scientific article

Potentiation of the P2X3 ATP receptor by PAR-2 in rat dorsal root ganglia neurons, through protein kinase-dependent mechanisms, contributes to inflammatory pain

scientific article published on 23 May 2012

Proteinase-activated receptor 2-mediated potentiation of transient receptor potential vanilloid subfamily 1 activity reveals a mechanism for proteinase-induced inflammatory pain.

scientific article

Re-evaluation of the phenotypic changes in L4 dorsal root ganglion neurons after L5 spinal nerve ligation

scientific article published on 03 November 2011

Recombinant interleukin-4 alleviates mechanical allodynia via injury-induced interleukin-4 receptor alpha in spinal microglia in a rat model of neuropathic pain.

scientific article

RhoA/ROCK pathway mediates p38 MAPK activation and morphological changes downstream of P2Y12/13 receptors in spinal microglia in neuropathic pain.

scientific article published on 14 August 2014

Role of Rho-associated coiled-coil containing protein kinase in the spinal cord injury induced neuropathic pain

scientific article published on 24 August 2020

Role of mitogen-activated protein kinase activation in injured and intact primary afferent neurons for mechanical and heat hypersensitivity after spinal nerve ligation.

scientific article published in November 2004

Roles of extracellular signal-regulated protein kinases 5 in spinal microglia and primary sensory neurons for neuropathic pain

scientific article published on 17 May 2007

Sensitization of TRPA1 by PAR2 contributes to the sensation of inflammatory pain

scientific article (publication date: July 2007)

Sensitization of TRPA1 by PAR2 contributes to the sensation of inflammatory pain.

scientific article published in October 2007

Suppression of the p75 neurotrophin receptor in uninjured sensory neurons reduces neuropathic pain after nerve injury.

scientific article

TRPA1 induced in sensory neurons contributes to cold hyperalgesia after inflammation and nerve injury

scientific article

TRPA1-expressing lamina propria mesenchymal cells regulate colonic motility

scientific article published on 02 May 2019

The role of ERK signaling and the P2X receptor on mechanical pain evoked by movement of inflamed knee joint

scientific article published on 17 April 2006

Tissue plasminogen activator in primary afferents induces dorsal horn excitability and pain response after peripheral nerve injury

scientific article published on 01 January 2004

Tissue type plasminogen activator induced in rat dorsal horn astrocytes contributes to mechanical hypersensitivity following dorsal root injury

scientific article published on 01 April 2007

Toll-like receptor 3 contributes to spinal glial activation and tactile allodynia after nerve injury

scientific journal article

Transforming growth factor-activated kinase 1 induced in spinal astrocytes contributes to mechanical hypersensitivity after nerve injury

scientific article published on 01 May 2008

Up-Regulation of Platelet-Activating Factor Synthases and its Receptor in Spinal Cord Contribute to Development of Neuropathic Pain following Peripheral Nerve Injury

scientific article published on February 2, 2012